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Pulmonary vein isolation

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https://www.readbyqxmd.com/read/27900452/microparticles-from-splenectomized-%C3%AE-thalassemia-hbe-patients-play-roles-on-procoagulant-activities-with-thrombotic-potential
#1
Phatchanat Klaihmon, Kunwadee Phongpao, Wasinee Kheansaard, Egarit Noulsri, Archrob Khuhapinant, Suthat Fucharoen, Noppawan Phumala Morales, Saovaros Svasti, Kovit Pattanapanyasat, Pornthip Chaichompoo
Thromboembolic events including cerebral thrombosis, deep vein thrombosis, and pulmonary embolism are major complications in β-thalassemia. Damaged red blood cells and chronic platelet activation in splenectomized β-thalassemia/HbE patients were associated with increased microparticles (MPs) releases into blood circulation. MPs are small membrane vesicles, which play important roles on coagulation. However, the role of MP in thalassemia is poorly understood. In this study, the effects of splenectomized-MPs on platelet activation and aggregation were investigated...
November 29, 2016: Annals of Hematology
https://www.readbyqxmd.com/read/27893055/assessment-of-use-vs-discontinuation-of-oral-anticoagulation-after-pulmonary-vein-isolation-in-patients-with-atrial-fibrillation
#2
Sara Själander, Fredrik Holmqvist, J Gustav Smith, Pyotr G Platonov, Milos Kesek, Peter J Svensson, Carina Blomström-Lundqvist, Fariborz Tabrizi, Jari Tapanainen, Dritan Poci, Anders Jönsson, Anders Själander
Importance: Pulmonary vein isolation (PVI) is a recommended treatment for patients with atrial fibrillation, but it is unclear whether it results in a lower risk of stroke. Objectives: To investigate the proportion of patients discontinuing anticoagulation treatment after PVI in association with the CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75 years [doubled], diabetes, stroke [doubled], vascular disease, age 65-74 years, sex category [female]) score, identify factors predicting stroke after PVI, and explore the risk of cardiovascular events after PVI in patients with and without guideline-recommended anticoagulation treatment...
November 23, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27889688/management-of-distal-deep-vein-thrombosis
#3
REVIEW
Helia Robert-Ebadi, Marc Righini
Isolated distal deep vein thrombosis (DVT), also known as calf DVT, represents up to 50% of all lower limb DVT in ultrasound series and is therefore a frequent medical condition. Unlike proximal DVT and pulmonary embolism (PE), which have been extensively studied and for which management is well standardized, much less is known on the optimal management of isolated calf DVT. Recent data arising from registries and non-randomized studies suggest that most distal DVTs do not extend to the proximal veins and have an uneventful follow-up when left untreated...
November 10, 2016: Thrombosis Research
https://www.readbyqxmd.com/read/27889553/long-term-outcomes-from-catheter-ablation-of-very-longstanding-persistent-atrial-fibrillation
#4
Karen P Phillips, Daniel T Walker
INTRODUCTION: Success rates for catheter ablation of longstanding persistent atrial fibrillation (AF) are significantly poorer than for recently persistent or paroxysmal forms. We report on single centre long term outcomes from ablation of very longstanding (> 2years) persistent AF. MATERIAL AND METHODS: A retrospective analysis of outcomes for patients undergoing catheter ablation for symptomatic very longstanding persistent AF between 2008 and 2013 was performed...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27886924/how-to-improve-cardiac-resynchronization-therapy-benefit-in-atrial-fibrillation-patients-pulmonary-vein-isolation-and-beyond
#5
REVIEW
Carola Gianni, Luigi Di Biase, Sanghamitra Mohanty, Yalçın Gökoğlan, Mahmut Fatih Güneş, Amin Al-Ahmad, J David Burkhardt, Andrea Natale
Although cardiac resynchronization therapy (CRT) is an important treatment of symptomatic heart failure patients in sinus rhythm with low left ventricular ejection fraction and ventricular dyssynchrony, its role is not well defined in patients with atrial fibrillation (AF). CRT is not as effective in patients with AF because of inadequate biventricular capture and loss of atrioventricular synchrony. Both can be addressed with catheter ablation of AF. It is still unclear if these therapies offer additive benefits in patients with ventricular dyssynchrony...
January 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/27886610/integration-of-intracardiac-echocardiography-and-computed-tomography-during-atrial-fibrillation-ablation-combining-ultrasound-contours-obtained-from-the-right-atrium-and-ventricular-outflow-tract
#6
Kohki Nakamura, Shigeto Naito, Kenichi Kaseno, Yosuke Nakatani, Takehito Sasaki, Naofumi Anjo, Eiji Yamashita, Koji Kumagai, Nobusada Funabashi, Yoshio Kobayashi, Shigeru Oshima
BACKGROUND: We aimed to optimize the acquisition of the left atrial (LA) and pulmonary vein (PV) ultrasound contours for more accurate integration of intracardiac echocardiography (ICE) and computed tomography (CT) using the CARTO(®) 3 system during atrial fibrillation (AF) ablation. METHODS: Eighty-five AF patients underwent integration of ICE and CT using (1) the LA roof and posterior wall contours acquired from the right atrium (RA), (2) all LA/PV contours from the RA (Whole-RA-integration), (3) the LA roof/posterior wall contours from the RA and right ventricular outflow tract (RVOT) (Posterior-RA/RV-integration), and (4) all LA/PV contours from the RA and RVOT (Whole-RA/RV-integration)...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27878420/a-5-year-clinical-follow-up-after-duty-cycled-phased-rf-ablation-of-paroxysmal-atrial-fibrillation
#7
Antoine Lepillier, Xavier Copie, Gilles Lascault, Olivier Paziaud, Olivier Piot
PURPOSE: Catheter radiofrequency ablation (RFA) is an effective treatment for symptomatic paroxysmal atrial fibrillation (AF). It has been demonstrated that the multielectrode pulmonary vein ablation catheter (PVAC) has favourable outcomes at 6-12 months post-ablation, but there are only few studies with a long-term follow-up. METHODS: We retrospectively reviewed 77 consecutive PVAC procedures in our centre, from November 2007 to December 2012. RFA was attempted in patients with symptomatic paroxysmal AF (mean age 58...
November 22, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27871986/second-generation-cryoballoon-ablation-without-the-use-of-real-time-recordings-a-novel-strategy-based-on-a-temperature-guided-approach-to-ablation
#8
Saverio Iacopino, Giacomo Mugnai, Ken Takarada, Gaetano Paparella, Erwin Ströker, Valentina De Regibus, Hugo Enrique Coutino-Moreno, Rajin Choudhury, Juan Pablo Abugattas de Torres, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia
BACKGROUND: The achievement of -40°C within 60 seconds has proven to independently predict durable PV isolation in the setting of second generation cryoballoon (CB-A; Medtronic; USA) ablation. OBJECTIVE: In the present study, we sought to evaluate a strategy based on the attainment of the specific parameter of -40°C within the first 60 seconds during cryoenergy applications in the setting of CB-A without the use of an inner lumen mapping catheter (ILMC) (Achieve; Medtronic, USA) for the visualisation of real time recordings (RTR)...
November 18, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27870975/comparisons-of-the-underlying-mechanisms-of-left-atrial-remodeling-after-repeat-circumferential-pulmonary-vein-isolation-with-or-without-additional-left-atrial-linear-ablation-in-patients-with-recurrent-atrial-fibrillation
#9
Chia-Hung Yang, Chung-Chuan Chou, Kuo-Chun Hung, Ming-Shien Wen, Po-Cheng Chang, Hung-Ta Wo, Cheng-Hung Lee, Fen-Chiung Lin
BACKGROUND: Radiofrequency catheter ablation (RFCA) is a potentially curative treatment for atrial fibrillation (AF), however, whether or not additional left atrial (LA) linear ablation for recurrent AF adversely affects LA remodeling is unknown. METHODS: Thirty-eight patients experiencing AF recurrence after the 1st circumferential pulmonary vein isolation (CPVI) underwent a repeat RFCA, including 20 and 18 patients receiving a repeat CPVI (group I) or CPVI plus LA linear ablation (group II), respectively...
November 7, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27863291/adenosine-guided-pulmonary-vein-isolation-versus-conventional-pulmonary-vein-isolation-in-patients-undergoing-atrial-fibrillation-ablation-an-updated-meta-analysis
#10
Nikolaos Papageorgiou, Rui Providência, Neil Srinivasan, Kostas Bronis, Francisco Moscoso Costa, Diogo Cavaco, Pedro Adragão, Dimitris Tousoulis, Ross J Hunter, Richard J Schilling, Oliver R Segal, Anthony Chow, Edward Rowland, Martin Lowe, Pier D Lambiase
BACKGROUND: Recurrent atrial fibrillation episodes following pulmonary vein isolation (PVI) are frequently due to reconnection of PVs. Adenosine can unmask dormant conduction, leading to additional ablation to improve AF-free survival. We performed a meta-analysis of the literature to assess the role of adenosine testing in patients undergoing atrial fibrillation (AF) ablation. METHODS: PubMed, EMBASE, and Cochrane databases were searched through until December 2015 for studies reporting on the role of adenosine guided-PVI versus conventional PVI in AF ablation...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27862561/long-term-outcome-of-left-atrial-voltage-guided-substrate-ablation-during-atrial-fibrillation-a-novel-adjunctive-ablation-strategy
#11
Atsuhiko Yagishita, J Rod Gimbel, Samer DE Oliveira, Harish Manyam, Dina Sparano, Ivan Cakulev, Judith Mackall, Mauricio Arruda
INTRODUCTION: Left atrium (LA) low voltage area (LVA) on 3-D electroanatomic bipolar voltage mapping (EAVM), as a surrogate for scar, is associated with poor AF ablation outcome. We evaluated the long-term outcome of a LVA-guided atrial fibrillation (AF) substrate modification strategy as an adjunct to pulmonary vein isolation (PVI). METHODS AND RESULTS: Two hundred and one consecutive patients with AF (82% persistent / Non-PAF, age 65 years), who underwent EAVM during AF prior to PVI, were divided into two groups according to the presence or absence of LVA outside the PV antra, defined as bipolar voltage of < 0...
November 12, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27862043/pulmonary-vein-isolation-with-the-cryoballoon-technique-feasibility-procedural-outcomes-and-adoption-in-the-real-world-data-from-one-shot-technologies-to-pulmonary-vein-isolation-1stop-project
#12
Luigi Padeletti, Antonio Curnis, Claudio Tondo, Maurizio Lunati, Stefano Porcellini, Roberto Verlato, Luigi Sciarra, Gaetano Senatore, Domenico Catanzariti, Loira Leoni, Maurizio Landolina, Pietro Delise, Saverio Iacopino, Paolo Pieragnoli, Giuseppe Arena
BACKGROUND: Catheter ablation (CA) is recommended for patients with drug refractory symptomatic atrial fibrillation (AF). "One Shot" catheters have been introduced to simplify CA and cryoballoon-ablation (CBA) is spreading rapidly. Few real-world data are available on standard clinical practice, mainly from single center experience. We aimed to evaluate clinical settings, demographics and acute procedural outcomes in a large cohort of patients treated with CBA. METHODS: 903 patients (73% male, mean age 59±11) underwent pulmonary veins CBA...
November 10, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27853943/endocardial-voltage-mapping-of-pulmonary-veins-with-an-ultra-high-resolution-system-to-evaluate-atrial-myocardial-extensions
#13
Francesco Santoro, Christian Sohns, Ardan M Saguner, Natale Daniele Brunetti, Christine Lemes, Shibu Mathew, Christian-H Heeger, Bruno Reißmann, Tilman Maurer, Johannes Riedl, Thomas Fink, Kentaro Hayashi, Feifan Ouyang, Matteo Di Biase, Karl-Heinz Kuck, Andreas Metzner
INTRODUCTION: Atrial fibrillation (AF) is mainly triggered by arrhythmogenic foci originating from atrial myocardial extensions (MEs) into the pulmonary veins (PVs). Aim of the study was to evaluate endocardial voltage maps of PVs as a surrogate parameter for the extent of MEs in subjects with AF through a ultra-high-density mapping system. METHODS: Sixty-four bipolar electrograms were recorded simultaneously from the Orion mini-basket catheter placed in 72 PVs of 18 consecutive patients with paroxysmal/persistent AF undergoing PV isolation (PVI)...
November 16, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27830886/anomalous-left-brachiocephalic-vein-important-vascular-anomaly-concomitant-with-congenital-anomalies-and-heart-diseases
#14
Shahram Kahkouee, Makan Sadr, Elham Pedarzadeh, Sara Fardin, Ali Borhani, Saeid Gholami, Ghazaleh Amjad
BACKGROUND: Anomalous left brachiocephalic vein (ALBCV) is a rare and less known systemic venous anomaly. Infrequently, this vein takes an abnormal course and passes to the right behind or beneath the aortic arch to create the superior vena cava (SVC). Its incidence was reported much higher in patients with congenital heart disease (CHD) especially in conotruncal and aortic arch anomalies. It could be misdiagnosed with normal or abnormal mediastinal structures. It also could make complication during surgeries or invasive strategies...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27828828/anatomic-relationship-between-left-coronary-artery-and-left-atrium-in-patients-undergoing-atrial-fibrillation-ablation
#15
Matteo Anselmino, Federica Torri, Federico Ferraris, Leonardo Calò, Davide Castagno, Sebastiano Gili, Chiara Rovera, Carla Giustetto, Fiorenzo Gaita
BACKGROUND: Atrial fibrillation transcatheter ablation (TCA) is, within available atrial fibrillation rhythm control strategies, one of the most effective. To potentially improve ablation outcome in case of recurrent atrial fibrillation after a first procedure or in presence of structural myocardial disease, isolation of the pulmonary veins may be associated with extensive lesions within the left atrium. To avoid rare, but potentially life-threatening, complications, thorough knowledge and assessment of left atrium anatomy and its relation to structures in close proximity are, therefore, mandatory...
November 8, 2016: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/27826130/focal-impulse-and-rotor-modulation-acute-procedural-observations-and-extended-clinical-follow-up
#16
Jonathan S Steinberg, Yash Shah, Advay Bhatt, Tina Sichrovsky, Aysha Arshad, Emily Hansinger, Dan Musat
BACKGROUND: Focal impulse and rotor modulation (FIRM) was based on the premise that atrial fibrillation (AF) is sustained by rotors which are sufficiently stable to be eliminated by targeted ablation. Early experience reported high success as compared to conventional strategies. OBJECTIVE: To report on a single-center experience with extended follow-up using FIRM in a variety of AF pts. METHODS: All FIRM-guided ablation procedures were included...
November 5, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27826128/durability-of-wide-area-left-atrial-appendage-isolation-results-from-extensive-catheter-ablation-for-the-treatment-of-persistent-atrial-fibrillation
#17
Bruno Reissmann, Andreas Rillig, Erik Wissner, Roland Tilz, Michael Schlüter, Christian Sohns, Christian Heeger, Shibu Mathew, Tilman Maurer, Christine Lemes, Thomas Fink, Peter Wohlmuth, Francesco Santoro, Johannes Riedl, Feifan Ouyang, Karl-Heinz Kuck, Andreas Metzner
BACKGROUND: Extensive ablation strategies are currently performed in addition to pulmonary vein isolation (PVI) to improve the clinical outcome of patients with drug-refractory persistent atrial fibrillation (AF). Ablation of complex fractionated atrial electrograms (CFAE), linear lesions and/or isolation of the left atrial appendage (LAA) are thought to improve arrhythmia-free survival. OBJECTIVE: This study sought to assess the durability of wide-area LAA isolation (LAAI) achieved by PVI, an anterior line and a mitral isthmus line...
November 5, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27823597/frequency-of-deep-vein-thrombosis-and-or-pulmonary-embolism-after-coronary-artery-bypass-grafting-investigation-regardless-of-clinical-suspicion
#18
Vitor B Viana, Emanoel R Melo, Mario Terra-Filho, Luis A Dallan, Maria M Gonzalez, Ludhmila A Hajjar, Fabio B Jatene, Luiz A Cesar, Caio B Vianna
Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and/or pulmonary embolism (PE). Many surgeons and clinicians believe that VTE after coronary artery bypass grafting (CABG) has little clinical significance because it is seldom diagnosed. This study aimed to identify VTE after CABG, independent of clinical suspicion. In this prospective, observational, single-center study, 100 patients underwent computed tomographic pulmonary angiography (multidetector-64) and lower extremity venous compressive ultrasound after elective CABG...
October 8, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27817752/right-aortic-arch-with-isolation-of-the-left-subclavian-artery-a-rare-association-with-airway-obstruction
#19
Putri Yubbu, Haifa A Latiff, Abdel Moneim Adam Abbaker
We present two interesting cases of isolated left subclavian artery from the pulmonary artery with symptoms of upper airway obstruction. The first patient had tetralogy of Fallot, pulmonary artery sling, bilateral superior caval veins, and left bronchial isomerism, suggesting heterotaxy syndrome. The second patient had a right aortic arch, isolated left subclavian artery, and bilateral arterial ducts. These two cases are interesting because of their rarity and uncommon presentation.
November 7, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27816321/safety-and-efficacy-of-contemporary-catheter-ablation-for-atrial-fibrillation-patients-with-a-history-of-cardioembolic-stroke-in-the-era-of-direct-oral-anticoagulants
#20
Kimitaka Nishizaki, Taihei Itoh, Masaomi Kimura, Yuichi Tsushima, Yoshihiro Shoji, Takahiko Kinjo, Yuji Ishida, Kenichi Sasaki, Daisuke Horiuchi, Shingo Sasaki, Hirofumi Tomita, Ken Okumura
BACKGROUND: The safety and efficacy of the contemporary atrial fibrillation (AF) ablation in patients with a recent or previous history of cardioembolic stroke (CS) or transient ischemic attack (TIA) remain to be established. METHODS: A total of 447 patients who underwent first-ever contact force (CF)-guided AF ablation with circumferential pulmonary vein isolation were included. Of these, 17 had CS or TIA within 6 months before ablation (Group 1), 30 more than 6 months before ablation (Group 2), and the other 400 without CS or TIA (Group 3)...
November 2, 2016: Journal of Cardiology
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