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https://www.readbyqxmd.com/read/29144874/evaluation-of-interfacial-gap-volume-of-two-low-shrinkage-composites-using-micro-computed-tomography
#1
Hna Al Nahedh, N S Sibai
OBJECTIVES: To investigate the efficacy of X-ray micro-computed tomography (μCT) in the detection and quantification of interfacial gap formation in standardized Class I and Class II resin composite restorations, to compare the interfacial gaps for two low-shrinkage resin composites with a methacrylate composite material, and to determine any correlation between the cavity configuration factor (C-factor) and the volume of gaps formed. METHODS AND MATERIALS: Sixty standardized Class I and Class II cavities were prepared and divided into six groups...
November 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28980314/haematopoietic-cell-transplantation-for-blastic-plasmacytoid-dendritic-cell-neoplasm-a-north-american-multicentre-collaborative-study
#2
Mohamed A Kharfan-Dabaja, Monzr M Al Malki, Uday Deotare, Renju V Raj, Najla El-Jurdi, Navneet Majhail, Mohamad A Cherry, Qaiser Bashir, Justin Darrah, Taiga Nishihori, Hassan Sibai, Mehdi Hamadani, Marcos de Lima, Aaron T Gerds, George Selby, Muzaffar H Qazilbash, Stephen J Forman, Ernesto Ayala, Jeffrey H Lipton, Parameswaran N Hari, Tariq Muzzafar, Ling Zhang, Horatiu Olteanu, Janelle Perkins, Lubomir Sokol, Ambuj Kumar, Sairah Ahmed
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is incurable with conventional therapies. Limited retrospective data have shown durable remissions after haematopoietic cell transplantation (HCT) [allogeneic (allo) or autologous (auto)]. We conducted a multicentre retrospective study in BPDCN patients treated with allo-HCT and auto-HCT at 8 centres in the United States and Canada. Primary endpoint was overall survival (OS). The population consisted of 45 consecutive patients who received an allo-HCT (n = 37) or an auto-HCT (n = 8) regardless of age, pre-transplant therapies, or remission status at transplantation...
October 4, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28942717/composite-neonatal-and-maternal-morbidities-with-small-versus-appropriate-for-gestational-age-among-uncomplicated-obese-women-undergoing-repeat-cesarean-delivery
#3
Ziad A Haidar, Oscar A Viteri, Susan Hosseini Nasab, Hind N Moussa, Baha M Sibai, Janice E Whitty
PURPOSE: Our goal was to compare composite neonatal and maternal morbidities (composite neonatal morbidity (CNM), composite maternal morbidity (CMM)) among deliveries with small for age (SGA) versus appropriate for gestational age (AGA; birthweight 10-89%) among obese versus non-obese women undergoing repeat cesarean delivery (CD). STUDY DESIGN: This is a secondary analysis of a prospective observational study. Women who had elective CD ≥37 weeks were studied...
October 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28942691/twin-transvaginal-cervical-length-at-16-20-weeks-and-prediction-of-preterm-birth
#4
Ashley E Hester, Nana-Ama E Ankumah, Suneet P Chauhan, Sean C Blackwell, Baha M Sibai
OBJECTIVE: Our objective was to determine if transvaginal cervical length at 16-20 weeks is predictive of preterm birth <34 weeks in a large cohort of twin pregnancies. STUDY DESIGN: This is a secondary analysis from a randomized trial of 17 alpha-hydroxyprogesterone caproate in twins to prevent preterm birth. Transvaginal cervical length was performed at 16-20-week gestation. The inclusion criteria were non-anomalous twins with transvaginal cervical length at 16-20 weeks...
October 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28885783/uterine-balloon-tamponade-for-the-management-of-postpartum-haemorrhage-a-challenge-and-an-opportunity-for-better-evidence
#5
O A Viteri, B M Sibai
No abstract text is available yet for this article.
September 8, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28885417/association-of-nonsteroidal-antiinflammatory-drugs-and-postpartum-hypertension-in-women-with-preeclampsia-with-severe-features
#6
Oscar A Viteri, Joey A England, Mesk A Alrais, Kayla A Lash, Maria I Villegas, Olaide A Ashimi Balogun, Suneet P Chauhan, Baha M Sibai
OBJECTIVE: To estimate whether nonsteroidal antiinflammatory drugs (NSAIDs) are associated with persistent postpartum hypertension in a cohort of women with preeclampsia and severe features. METHODS: We conducted a retrospective cohort study at a single, tertiary center from January 2013 to December 2015. All women diagnosed with severe preeclampsia who remained hypertensive for greater than 24 hours after delivery were included. The primary outcome was the rate of persistent postpartum hypertension, defined as systolic blood pressure 150 mm Hg or greater or diastolic 100 mm Hg or greater (or both), on two occasions, at least 4 hours apart...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28872682/%C3%AE-2-himachalen-6-ol-protects-against-skin-cancer-development-in%C3%A2-vitro-and-in%C3%A2-vivo
#7
Hamid E Daaboul, Costantine F Daher, Robin I Taleb, Joelle Boulos, Kikki Bodman-Smith, Petra Boukamp, Wassim N Shebaby, Carol Dagher, Mirvat El-Sibai, Mohamad A Mroueh
BACKGROUND: Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses remarkable in-vitro anticancer activity and antitumour promoting effect against DMBA/TPA skin carcinogenesis in mice. Chemical analysis of DCOE led to the isolation of the β-2-himachalen-6-ol (HC), major sesquiterpene with a potent anticancer activity against various colon, breast, brain and skin cancer cells. This study investigated the anticancer activity of HC against invasive epidermal squamous cell carcinoma cells and evaluated its effect in a DMBA/TPA skin carcinogenesis Balb/c murine model...
September 5, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28872218/adolescents-self-perceived-and-actual-weight-which-plays-a-dominant-role-in-weight-loss-behaviour-in-lebanon
#8
S Assaad, S Anouti, F Naja, L Nasreddine, N Hwalla, A M Sibai
BACKGROUND: The decision to lose weight among adolescents is complex and is guided by a number of body-related factors. This study examined the extent of agreement between actual weight, measured as body mass index, and self-perceived weight and assessed their relative importance in weight loss behaviour among Lebanese adolescents. METHODS: Data on 278 adolescents aged 13-17 years were drawn from the nationwide Nutrition and Non-Communicable Disease Risk Factor Survey (Lebanon, 2009)...
September 4, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28865040/the-impact-of-peri-operative-dexamethasone-administration-on-the-normal-hypothalamic-pituitary-adrenal-response-to-major-surgical-procedures
#9
Katia El-Sibai, Aman Rajpal, Ribal Al-Aridi, Warren R Selman, Baha M Arafah
BACKGROUND: Surgical procedures are associated with activation of the hypothalamic-pituitary-adrenal axis (HPA). Studies examining HPA dynamics peri-operatively are limited and the modulating influence of peri-operatively administered glucocorticoids on that is not well established. This investigation examined alterations in HPA function and the impact of dexamethasone (DEX) administration during the peri-operative period. METHODS: We examined HPA function in 297 patients with normal function who had surgical procedures including pituitary mass resection (n = 191), craniotomy (n = 17) and other thoracic/ abdominal/ pelvic surgeries (n = 89)...
October 2017: Endocrine
https://www.readbyqxmd.com/read/28852635/parental-perception-of-oral-health-related-quality-of-life-of-syrian-refugee-children
#10
Sharat Chandra Pani, Salam Atef Al-Sibai, Akanksha S Rao, Samira Najeebullah Kazimoglu, Hezekiah Adeyemi Mosadomi
AIMS AND OBJECTIVES: The conflict in Syria has resulted in the displacement of over 5 million people, many of whom intend to return home at the cessation of hostilities. Oral health plays a critical role in early childhood and this study aimed to qualitatively and quantitatively assess the oral health-related quality of life (OHRQoL) of these children. MATERIALS AND METHODS: The quantitative assessment of OHRQoL was done using a validated Arabic version of the short-form Parental-Caregiver Perceptions Questionnaire-8 (P-CPQ-8)...
July 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28782499/antitumor-activity-of-%C3%AE-2-himachalen-6-ol-in-colon-cancer-is-mediated-through-its-inhibition-of-the-pi3k-and-mapk-pathways
#11
Hamid E Daaboul, Costantine F Daher, Kikki Bodman-Smith, Robin I Taleb, Wassim N Shebaby, Joelle Boulos, Carole Dagher, Mohamad A Mroueh, Mirvat El-Sibai
Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses in vitro and in vivo anticancer activities. Chemical analysis of DCOE led to the isolation of β-2-himachalen-6-ol (HC) which exhibited potent anticancer activity against colon, breast, brain and skin cancer cells. The present study investigates the anticancer activity of HC against SW1116 colon cancer cell lines, and evaluates its effect in a 1,2-dimethylhydrazine (DMH) colon carcinogenesis black6 mice model. The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit...
September 25, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28748239/phototoxicity-of-strained-ru-ii-complexes-is-it-the-metal-complex-or-the-dissociating-ligand
#12
Daniel F Azar, Hassib Audi, Stephanie Farhat, Mirvat El-Sibai, Ralph J Abi-Habib, Rony S Khnayzer
A photochemically dissociating ligand in Ru(bpy)2(dmphen)Cl2 [bpy = 2,2'-bipyridine; dmphen = 2,9-dimethyl-1,10-phenanthroline] was found to be more cytotoxic on the ML-2 Acute Myeloid Leukemia cell line than Ru(bpy)2(H2O)2(2+) and prototypical cisplatin. Our findings illustrate the potential potency of diimine ligands in photoactivatable Ru(ii) complexes.
September 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28715482/impact-of-maternal-body-mass-index-and-gestational-weight-gain-on-neonatal-outcomes-among-healthy-middle-eastern-females
#13
Tatiana Papazian, Georges Abi Tayeh, Darine Sibai, Hala Hout, Imad Melki, Lydia Rabbaa Khabbaz
BACKGROUND: Studies on the relative impact of body mass index in women in childbearing age and gestational weight gain on neonatal outcomes are scarce in the Middle East. OBJECTIVES: The primary objective of this research was to assess the impact of maternal body mass index (BMI) and gestational weight gain (GWG) on neonatal outcomes. The effect of maternal age and folic acid supplementation before and during pregnancy was also examined. SUBJECTS AND METHODS: This is a retrospective cross sectional observational study of 1000 full term deliveries of women enrolled thru the National Collaborative Perinatal Neonatal Network, in Lebanon...
2017: PloS One
https://www.readbyqxmd.com/read/28711573/distribution-and-impact-of-comorbidities-on-survival-and-leukemic-transformation-in-myeloproliferative-neoplasm-associated-myelofibrosis-a-retrospective-cohort-study
#14
Justyna Bartoszko, Tony Panzarella, Caroline Jane McNamara, Anthea Lau, Aaron D Schimmer, Andre C Schuh, Hassan Sibai, Dawn Maze, Karen W L Yee, Rebecca Devlin, Vikas Gupta
BACKGROUND: We sought to describe the distribution and impact of comorbidities on outcomes in patients with myelofibrosis, a disease characterized by aberrant bone marrow function with eventual fibrosis. Comorbidities were scored using the Adult Comorbidity Evaluation-27 (ACE-27) and the Hematopoietic Cell Transplant Comorbidity Index (HCT-CI), in which a score ≥ 3 indicates severe comorbidities. PATIENTS AND METHODS: We conducted a retrospective study of 306 patients with a confirmed diagnosis of myelofibrosis...
June 29, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28708975/short-term-costs-of-preeclampsia-to-the-united-states-health-care-system
#15
Warren Stevens, Tiffany Shih, Devin Incerti, Thanh G N Ton, Henry C Lee, Desi Peneva, George A Macones, Baha M Sibai, Anupam B Jena
BACKGROUND: Preeclampsia is a leading cause of maternal morbidity and mortality and adverse neonatal outcomes. Little is known about the extent of the health and cost burden of preeclampsia in the United States. OBJECTIVE: This study sought to quantify the annual epidemiological and health care cost burden of preeclampsia to both mothers and infants in the United States in 2012. STUDY DESIGN: We used epidemiological and econometric methods to assess the annual cost of preeclampsia in the United States using a combination of population-based and administrative data sets: the National Center for Health Statistics Vital Statistics on Births, the California Perinatal Quality Care Collaborative Databases, the US Health Care Cost and Utilization Project database, and a commercial claims data set...
September 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28697235/preclinical-evaluation-of-spatial-frequency-domain-enabled-wide-field-quantitative-imaging-for-enhanced-glioma-resection
#16
Mira Sibai, Carl Fisher, Israel Veilleux, Jonathan T Elliott, Frederic Leblond, David W Roberts, Brian C Wilson
5-Aminolevelunic acid-induced protoporphyrin IX (PpIX) fluorescence-guided resection (FGR) enables maximum safe resection of glioma by providing real-time tumor contrast. However, the subjective visual assessment and the variable intrinsic optical attenuation of tissue limit this technique to reliably delineating only high-grade tumors that display strong fluorescence. We have previously shown, using a fiber-optic probe, that quantitative assessment using noninvasive point spectroscopic measurements of the absolute PpIX concentration in tissue further improves the accuracy of FGR, extending it to surgically curable low-grade glioma...
July 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28690885/cancer-research-in-the-arab-world-a-review-of-publications-from-seven-countries-between-2000-2013
#17
REVIEW
Randah R Hamadeh, Saif M Borgan, Abla M Sibai
This review aimed to examine trends in cancer research in the Arab world and identify existing research gaps. A search of the MEDLINE® database (National Library of Medicine, Bethesda, Maryland, USA) was undertaken for all cancer-related publications published between January 2000 and December 2013 from seven countries, including Bahrain, Kuwait, Iraq, Lebanon, Morocco, Palestine and Sudan. A total of 1,773 articles were identified, with a significant increase in yearly publications over time (P <0.005)...
May 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28651448/adverse-pregnancy-outcomes-in-deliveries-prior-to-at-and-beyond-39-weeks-low-and-high-risk-women
#18
Hind N Moussa, Susan Hosseini Nasab, Farah H Amro, Jennifer Hoayek, Ziad A Haidar, Sean C Blackwell, Baha M Sibai
BACKGROUND: Hypertensive disorders are associated with maternal and neonatal complications. Though they are more common in women with history of prior preeclampsia, they can occur in uncomplicated pregnancies. OBJECTIVE: To determine the proportion of adverse pregnancy outcomes in deliveries prior to or at ≥39 weeks, in uncomplicated singleton nulliparous women (low-risk), as well as women with history of preeclampsia in a prior gestation (high-risk). STUDY DESIGN: This was a secondary analysis from the multicenter trials of low dose aspirin for preeclampsia prevention in low and high-risk pregnancies...
July 18, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28648694/removal-notice-to-the-relationship-between-primary-cesarean-delivery-skin-incision-type-and-wound-complications%C3%A2-in%C3%A2-women-with-morbid-obesity-am-j-obstet-gynecol-2014-210-319-e1-4
#19
Caroline C Marrs, Hind N Moussa, Baha M Sibai, Sean C Blackwell
This article has been removed: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been removed at the request of the Editors-in-Chief and Authors. The original publication reported that univariate analysis showed that a vertical skin incision in obese women undergoing Cesarean delivery was associated with a higher odds ratio for wound complications than a transverse skin incision. Multivariable analyses showed a reversal of the association (i...
July 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28595467/remissions-after-third-induction-chemotherapy-for-primary-non-responders-with-acute-myeloid-leukemia-aml-are-uncommon-and-short-lived
#20
Sara Farshchi Zarabi, Steven Chan, Vikas Gupta, Dina Khalaf, Andrzej Lutynski, Mark D Minden, Amr Rostom, Anna Rydlewski, Andre C Schuh, Hassan Sibai, Karen W L Yee, Aaron D Schimmer
No abstract text is available yet for this article.
June 9, 2017: Leukemia & Lymphoma
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