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https://www.readbyqxmd.com/read/29789779/outcomes-in-cardiogenic-shock-patients-with-extracorporeal-membrane-oxygenation-use-a-matched-cohort-study-in-hospitals-across-the-united-states
#1
Rayan El Sibai, Rana Bachir, Mazen El Sayed
Background: ECMO is increasingly used for patients with critical illnesses. This study examines ECMO use in patients with cardiogenic shock in US hospitals and associated outcomes (mortality, hospital length of stay, and total hospital charges). Methods: A matched cohort retrospective study was conducted using the 2013 Nationwide Emergency Department Sample. Cardiogenic shock visits were matched (1 : 1) and compared based on ECMO use. Results: Patients with ECMO ( N = 802) were compared to patients without ECMO ( N = 805)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29764456/a-scoping-review-of-reporting-ethical-research-practices-in-research-conducted-among-refugees-and-war-affected-populations-in-the-arab-world
#2
Jihad Makhoul, Rana F Chehab, Zahraa Shaito, Abla M Sibai
BACKGROUND: Ethical research conduct is a cornerstone of research practice particularly when research participants include vulnerable populations. This study mapped the extent of reporting ethical research practices in studies conducted among refugees and war-affected populations in the Arab World, and assessed variations by time, country of study, and study characteristics. METHODS: An electronic search of eight databases resulted in 5668 unique records published between 2000 and 2013...
May 15, 2018: BMC Medical Ethics
https://www.readbyqxmd.com/read/29701045/-effects-of-subcutaneous-embedding-of-thumb-tack-needle-on-tear-film-in-patients-with-dry-eye
#3
Hongjie Ma, Lei Feng, Jialiang Wang, Zhimin Yang
OBJECTIVE: To observe the effects of subcutaneous embedding of thumb-tack needle combined with mytear and simple mytear on tear film in patients with dry eye. METHODS: Eighty patients of dry eye (160 eyes) were randomly divided into an observation group and a control group, 40 cases in each group. The 0.1% sodium hyaluronate eye drop (alice) was applied in the control group, four times per day for two weeks. On the basis of the control group, the subcutaneous embedding of thumb-tack needle was used at ① Cuanzhu (BL 2), Sizhukong (SJ 23), Sibai (ST 2), ② Yintang (EX-HN 3), Yuyao (EX-HN 4), Taiyang (EX-HN 5)...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29701044/-special-penetration-needling-for-refractory-peripheral-facial-paralysis
#4
Rongjuan Cao, Xiaohu Qiu, Xiaokun Xie
OBJECTIVE: To observe the clinical effect difference between special penetration needling and conventional penetration needling for the refractory peripheral facial paralysis. METHODS: A total of 97 patients with intractable facial paralysis were randomized into an observation group (49 cases and 2 dropping) and a control group (48 cases and 4 dropping). In the observation group, special penetration needling at an angle about 45° between the penetration needle and paralysis muscle bundle was used, Yangbai (GB 14) through Touwei (ST 8), Yangbai (GB 14) through Shangxing (GV 23), Sizhukong (TE 23) through Yuyao (EX-HN 4), Qianzhen (Extra) through Yingxiang (LI 20), mutual penetration between Yingxiang (LI 20) and Jiache (ST 6)...
March 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29674280/the-chemotherapeutic-effect-of-%C3%AE-2-himachalen-6-ol-in-chemically-induced-skin-tumorigenesis
#5
Hamid E Daaboul, Carole Dagher, Robin I Taleb, Kikki Bodman-Smith, Wassim N Shebaby, Mirvat El-Sibai, Mohamad A Mroueh, Costantine F Daher
β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. The present study investigates the in vitro anticancer activity of HC and its effect on papillomas induced using a DMBA/TPA skin carcinogenesis mouse model. HaCaT-ras II-4 epidermal squamous cell viability was assessed using WST-1 kit. Cell cycle was analyzed by flow cytometry, and pro/anti-apoptotic proteins were measured using western blot. Mice papillomas were induced by DMBA and promoted with TPA for 18 weeks...
April 16, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29658615/the-integration-and-management-of-noncommunicable-diseases-in-primary-health-care
#6
EDITORIAL
Slim Slama, Asmus Hammerich, Ahmed Mandil, Abla Mehio Sibai, Jaakko Tuomilehto, Kremlin Wickramasinghe, Tom McGee
No abstract text is available yet for this article.
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29611286/high-responsivity-photodetection-by-a-self-catalyzed-phase-pure-p-gaas-nanowire
#7
Hassan Ali, Yunyan Zhang, Jing Tang, Kai Peng, Sibai Sun, Yue Sun, Feilong Song, Attia Falak, Shiyao Wu, Chenjiang Qian, Meng Wang, Zhanchun Zuo, Kui-Juan Jin, Ana M Sanchez, Huiyun Liu, Xiulai Xu
Defects are detrimental for optoelectronics devices, such as stacking faults can form carrier-transportation barriers, and foreign impurities (Au) with deep-energy levels can form carrier traps and nonradiative recombination centers. Here, self-catalyzed p-type GaAs nanowires (NWs) with a pure zinc blende (ZB) structure are first developed, and then a photodetector made from these NWs is fabricated. Due to the absence of stacking faults and suppression of large amount of defects with deep energy levels, the photodetector exhibits room-temperature high photoresponsivity of 1...
April 3, 2018: Small
https://www.readbyqxmd.com/read/29579757/liberal-versus-indicated-maternal-oxygen-supplementation-in-labor-a-before-and-after-trial
#8
Nana-Ama E Ankumah, Sean C Blackwell, Mesk A Alrais, Farah H Amro, Rachel L Wiley, Patricia Heale, Maria Hutchinson, Baha M Sibai
BACKGROUND:  Although supplemental oxygen (SO2 ) is routinely administered to laboring gravidas, benefits and harms are not well studied. OBJECTIVE:  This article compares strategies of liberal versus indicated SO2 therapy during labor on cesarean delivery (CD) rate and neonatal outcomes. STUDY DESIGN:  A controlled, before-and-after trial of laboring women with term, singleton pregnancies. During an initial 8-week period, maternal SO2 was administered at the discretion of the provider followed by an 8-week period where SO2 was to be given only for protocol indications...
March 26, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29562260/towards-an-optimal-luteal-support-modality-in-agonist-triggered-cycles-a-randomized-clinical-trial
#9
E A Elgindy, H Sibai, M I Mostafa, A Gibreel, E Darwish, H Maghraby
STUDY QUESTION: In ICSI patients with high risk of ovarian hyperstimulation syndrome (OHSS), are antagonist cycles triggered by gonadotropin releasing hormone (GNRH) agonist with a specialized luteal support regimen associated with comparable ongoing pregnancy rate (OPR) and less OHSS than those triggered by hCG? SUMMARY ANSWER: In antagonist ICSI cycles, GnRH agonist triggering with a specialized luteal support regimen is associated with comparable OPR to those triggered by hCG but may be less likely to be associated with OHSS...
June 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29557474/a-long-lived-cuprous-bis-phenanthroline-complex-for-the-photodynamic-therapy-of-cancer
#10
Cynthia Al Hageh, Majd Al Assaad, Zeinab El Masri, Nawar Samaan, Mirvat El-Sibai, Christian Khalil, Rony S Khnayzer
Copper is an earth-abundant and a biologically essential metal that offers a promising alternative to noble metals in photochemistry and photobiology. In this work, a series of sterically encumbered Cu(i) bis-phenanthroline complexes were investigated for their use in photochemotherapy (PCT). It was found that Cu(dsbtmp)2+ [dsbtmp = 2,9-disec-butyl-3,4,7,8-tetramethyl-1,10-phenanthroline] (compound 3), which possessed the longest excited state lifetime, exhibited significant in vitro photocytotoxicity on A375 (human malignant melanoma) and A549 (human lung carcinoma) cell lines...
April 3, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29544730/liberal-red-blood-cell-transfusions-impair-quality-of-life-after-cardiac-surgery
#11
A González-Pérez, J Z Al-Sibai, P Álvarez-Fernández, P Martínez-Camblor, M Argüello-Junquera, J M García-Gala, E Martínez-Revuelta, J Silva, C Morís, G M Albaiceta
BACKGROUND: The optimal blood management after cardiac surgery remains controversial. Moreover, blood transfusions may have an impact on long-term outcomes. OBJECTIVE: The aim of this study is to characterize the impact of liberal red blood cell transfusions on Health-Related Quality of life (HRQoL) after cardiac surgery. METHODS: We studied a cohort of 205 consecutive patients after ICU discharge. Baseline characteristics and clinical data were recorded, and HRQoL was assessed using the EuroQoL-5D instrument, applied 6 months after ICU discharge...
March 12, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29518628/aml-refractory-to-primary-induction-with-ida-flag-has-a-poor-clinical-outcome
#12
Simon Kavanagh, Emily Heath, Rose Hurren, Marcela Gronda, Samir H Barghout, Sanduni U Liyanage, Thirushi P Siriwardena, Jaime Claudio, Tong Zhang, Mahadeo Sukhai, Tracy L Stockley, Suzanne Kamel-Reid, Amr Rostom, Andrzej Lutynski, Dina Khalaf, Anna Rydlewski, Steven M Chan, Vikas Gupta, Dawn Maze, Hassan Sibai, Andre C Schuh, Karen Yee, Mark D Minden, Aaron D Schimmer
We evaluated outcomes of 100 patients with high risk AML treated with Ida-FLAG induction as first-line therapy. 72 achieved remission with one cycle; 19 did not. High risk cytogenetics and TP53 mutations were associated with failure to achieve remission. In those reaching remission, allogeneic bone marrow transplantation was associated with better relapse-free and overall survival. Those not achieving remission with induction therapy were extremely unlikely to reach remission with further therapy and had a dismal prognosis...
May 2018: Leukemia Research
https://www.readbyqxmd.com/read/29452731/submersion-injuries-in-the-united-states-patients-characteristics-and-predictors-of-mortality-and-morbidity
#13
Rayan El Sibai, Rana Bachir, Mazen El Sayed
INTRODUCTION: Drowning leads to 372,000 deaths annually worldwide and to severe morbidity secondary to asphyxiation or aspiration. Previous studies described submersion injuries mainly in the pediatric population. This study describes characteristics of patients presenting with submersion injuries to United States emergency departments (EDs) and identifies predictors of poor outcomes (death or long term neurologic deficits) after drowning. METHODS: This retrospective cross-sectional study included ED visits for submersion injuries from the United States 2013 Nationwide Emergency Department Sample (NEDS) dataset using discharge data (CCS diagnosis codes)...
March 2018: Injury
https://www.readbyqxmd.com/read/29421927/twin-gestation-in-a-swyer-syndrome-patient-with-superimposed-pre-eclampsia
#14
Jaimin S Shah, Oscar A Viteri, Monica Longo, Mazen Abdallah, Baha Sibai
No abstract text is available yet for this article.
February 8, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29350489/bioderived-dna-nanomachines-for-potential-uses-in-biosensing-diagnostics-and-therapeutic-applications
#15
REVIEW
Chava Angell, Mingxuan Kai, Sibai Xie, Xiangyi Dong, Yi Chen
Beside its genomic properties, DNA is also recognized as a novel material in the field of nanoengineering. The specific bonding of base pairs can be used to direct the assembly of highly structured materials with specific nanoscale features such as periodic 2D arrays, 3D nanostructures, assembly of nanomaterials, and DNA nanomachines. In recent years, a variety of DNA nanomachines are developed because of their many potential applications in biosensing, diagnostics, and therapeutic applications. In this review, the fuel-powered motors and secondary structure motors, whose working mechanisms are inspired or derived from natural phenomena and nanomachines, are discussed...
January 19, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29298455/preterm-preeclampsia-with-severe-features-composite-maternal-and-neonatal-morbidities-associated-with-fetal-growth-restriction
#16
Olaide Ashimi Balogun, Raminder K Khanagura, Heather R Kregel, Farah H Amro, Baha M Sibai, Suneet P Chauhan
OBJECTIVE:  The objective of this study was to compare adverse pregnancy outcomes between fetuses with estimated fetal weight (EFW) < 10 to > 10% in women with preterm preeclampsia (PE) with severe features. MATERIALS AND METHODS:  All women with preterm PE with severe features and nonanomalous singletons with EFW were identified at a tertiary center. Women with oligohydramnios or absent/reversed umbilical Doppler velocimetry were excluded. Using multivariable analysis, we compared the composite maternal and neonatal morbidities (CMM and CNM) between those with appropriate for gestational age (AGA) fetal growth, defined as EFW at 10 to 90th versus those with fetal growth restriction (FGR), defined as EFW < 10th percentile for gestational age (GA)...
January 3, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29296819/impact-of-genomic-alterations-on-outcomes-in-myelofibrosis-patients-undergoing-jak1-2-inhibitor-therapy
#17
Jay Y Spiegel, Caroline McNamara, James A Kennedy, Tony Panzarella, Andrea Arruda, Tracy Stockley, Mahadeo Sukhai, Mariam Thomas, Justyna Bartoszko, Jenny Ho, Nancy Siddiq, Dawn Maze, Aaron Schimmer, Andre Schuh, Hassan Sibai, Karen Yee, Jamie Claudio, Rebecca Devlin, Mark D Minden, Suzanne Kamel-Reid, Vikas Gupta
In myelofibrosis (MF), driver mutations in JAK2, MPL, or CALR impact survival and progression to blast phase, with the greatest risk conferred by triple-negative status. Subclonal mutations, including mutations in high-molecular risk (HMR) genes, such as ASXL1, EZH2, IDH1/2, and SRSF2 have also been associated with inferior prognosis. However, data evaluating the impact of next-generation sequencing in MF patients treated with JAK1/2 inhibitors are lacking. Using a 54-gene myeloid panel, we performed targeted sequencing on 100 MF patients treated with ruxolitinib (n = 77) or momelotinib (n = 23) and correlated mutational profiles with treatment outcomes...
September 12, 2017: Blood Advances
https://www.readbyqxmd.com/read/29284265/wannier-koopmans-method-calculations-of-2d-material-band-gaps
#18
Mouyi Weng, Sibai Li, Jiaxin Zheng, Feng Pan, Lin-Wang Wang
A major drawback of the widely successful density functional theory is its underestimation of the material band gap. Various methods have been proposed to correct its band gap predictions. Wannier Koopmans method (WKM) is recently developed for this purpose to predict the band gap of extended 3D bulk systems. While the WKM has also been shown to be successful for isolated molecules, it is still a question whether it will work for 2D materials that are in between the 0D molecules and 3D bulk systems. We apply the WKM to 16 commonly known well studied 2D materials and find that the WKM predicted band gaps are on par with their GW calculated results...
January 18, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29276165/caesarean-delivery-surgical-site-infection-what-are-expected-rates-and-potentially-modifiable-risk-factors
#19
Ziad A Haidar, Susan Hosseini Nasab, Hind N Moussa, Baha M Sibai, Sean C Blackwell
OBJECTIVE: This study sought to determine baseline Caesarean delivery (CD) surgical site infection (SSI) rates in various patient subgroups and to identify potentially modifiable and non-modifiable risk factors for SSI. METHODS: This is a secondary analysis of a multicentre CD registry. Women who underwent CD were divided into SSI versus no SSI. SSI was defined as an infection that occurred in the part of the body where the surgery took place, within 30 days of surgery...
December 21, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29241573/gaps-and-opportunities-for-nutrition-research-in-relation-to-non-communicable-diseases-in-arab-countries-call-for-an-informed-research-agenda
#20
REVIEW
Farah Naja, Hibeh Shatila, Lokman Meho, Mohamad Alameddine, Sally Haber, Lara Nasreddine, Abla Mehio Sibai, Nahla Hwalla
Effective public health nutrition interventions are needed to curb the escalating prevalence of non-communicable diseases (NCDs) in many Arab countries. In order to generate the scientific evidence needed for the success of these interventions, an informed research agenda should be developed. The purpose of this review is to identify gaps and opportunities for research on nutrition and NCDs among Arab countries, which is an important step towards the formulation of this research agenda. Published papers that addressed nutrition and NCDs in Arab countries between the years 2006 and 2015 were reviewed (n=824)...
November 2017: Nutrition Research
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