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https://www.readbyqxmd.com/read/29325263/-analysis-of-2-204-stillbirths-in-11-hospitals-of-guangdong-province
#1
L Yu, M Tang, X H Fan, H M Du, H Tang, P Chen, S L Xing, C H Su, D J Chen
Objective: To analyze the incidence and causes of stillbirth in 11 hospitals of Guangdong province, and to explore the appropriate interventions. Methods: Clinical data of stillbirth in 11 hospitals of Guangdong province were collected from January 2014 to December 2016. The gestational weeks, causes, maternal conditions and other factors were analyzed. Results: (1) From 2014 to 2016, 103 472 newborns were delivered in the 11 hospitals, and the number of stillbirth was 2 204, with the incidence of 2.13%. Among them, 0...
December 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29304769/a-comparison-of-misoprostol-vaginal-insert-and-misoprostol-vaginal-tablets-for-induction-of-labor-in-nulliparous-women-a-retrospective-cohort-study
#2
Kjersti Engen Marsdal, Ingvil Krarup Sørbye, Lise C Gaudernack, Mirjam Lukasse
BACKGROUND: Since Misoprostol Vaginal Insert (MVI - Misodel ®) was approved for labor induction in Europe in 2013, to date, no study has been published comparing MVI to Misoprostol vaginal tablets (MVT). The aim of this study, performed as part of a quality improvement project, was to compare the efficacy and safety of 200 μg MVI versus 25 μg MVT for labor induction in nulliparous women. METHODS: This retrospective cohort study included 171 nulliparous singleton term deliveries induced with MVI (n = 85) versus MVT (n = 86) at Oslo University Hospital Rikshospitalet, Norway, from November 2014 to December 2015...
January 5, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29286493/twenty-five-years-of-the-national-academy-of-medical-sciences-of-ukraine-progress-and-priorities-for-future-of-radiation-medicine-and-biology
#3
D Bazyka
After the creation of the Academy of Medical Sciences of Ukraine in 1993 the Research Center for Radiation Medicine was among the first institutions to join the Academy (fig. 1). Estab lishing the Academy was among the first steps of the independent Ukrainian government and aimed to provide a high level health care for population. It was extremely needed for the minimization of Chornobyl medical consequences. This choice was related to a growing recognition of the scientific research in fulfilling the Сenter's mission - study of the effects of low dose radiation on human body and radiation protection of the exposed population...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29272996/spontaneous-first-trimester-miscarriage-rates-per-woman-among-parous-women-with-1-or-more-pregnancies-of-24-weeks-or-more
#4
Judy Slome Cohain, Rina E Buxbaum, David Mankuta
BACKGROUND: The purpose of this study was to quantify spontaneous first trimester miscarriage rates per woman among parous women. A vast amount of data has accumulated regarding miscarriage rates per recognized pregnancy as well as about recurrent miscarriage. This is the second study of miscarriage rates per woman in a parous population and the first study of recurrent and non-recurrent, spontaneous first trimester miscarriage rates per woman in a large parous population. METHODS: Extraction of the following variables from all delivery room admissions from both Hadassah Medical Centers in Jerusalem Israel, 2004-2014: # of first trimester spontaneous miscarriages, # live births; # living children; age on admission, pre-pregnancy height and weight, any smoking this pregnancy, any alcohol or drug abuse this pregnancy, blood type, history of ectopic pregnancy, history of cesarean surgery (CS) and use of any fertility treatment(s)...
December 22, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29211491/complications-and-care-related-to-pregnancy-labor-and-delivery-among-active-component-service-women-u-s-armed-forces-2012-2016
#5
Shauna Stahlman, Catherine T Witkop, Leslie L Clark, Stephen B Taubman
Diagnoses of "complications of pregnancy, childbirth, and the puerperium" include both morbid complications and indications for routine care of pregnant women. During 2012-2016, a total of 55,601 U.S. service members with live births (n=63,879) had 657,060 medical encounters with primary diagnoses of "pregnancy complications." The most frequent diagnoses were "other" specified conditions complicating pregnancy, childbirth, or the puerperium. Numbers of medical encounters with a primary (first-listed) diagnosis of any pregnancy-related complication or indication for care decreased marginally each year between 2012 (n=178,703) and 2016 (n=146,282)...
November 2017: MSMR
https://www.readbyqxmd.com/read/29201427/predictors-of-long-acting-and-permanent-contraceptive-methods-utilization-among-women-in-rural-north-shoa-ethiopia
#6
Fantahun Ayenew Mekonnen, Wassie Negash Mekonnen, Solomon Hailemeskel Beshah
Background: According to available evidence, one in three married women in Ethiopia tends to avoid multiple children. On the other hand, women using Long Acting and Permanent Contraceptive Methods (LAPMs) are just 5 %. So, we aimed at identifying the factors associated with the utilization of LAPMs. Methods: We conducted a community based unmatched case control study among married women living in the rural areas of North Shoa zone, Ethiopia, in March 2015. The cases were married women using LAPMs, while controls were married women who were using modern short term methods...
2017: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29182088/perinatal-maternal-mortality-in-sickle-cell-anemia-two-case-reports-and-review-of-the-literature
#7
Sanaa Rizk, Elizabeth D Pulte, David Axelrod, Samir K Ballas
As outcomes of patients with sickle cell anemia improve and survival into adulthood with good quality of life and expectation of long-term survival becomes more common, challenges have developed, including issues related to reproduction. Pregnancy is frequently complicated in patients with sickle cell anemia with mortality up to 4.0%. Here we report maternal perinatal mortality in two women with sickle cell anemia who died post-partum due to acute chest syndrome (ACS), caused by bone marrow fat embolism and review the literature pertinent to this subject...
November 28, 2017: Hemoglobin
https://www.readbyqxmd.com/read/29179271/-relationship-between-the-risk-of-emergency-cesarean-section-for-nullipara-with-the-prepregnancy-body-mass-index-or-gestational-weight-gain
#8
R F Zhao, W Y Zhang, L Zhou
Objective: To investigate the risk of emergency cesarean section during labor with the pre-pregnancy body mass index or gestational weight gain. Methods: A total of 6 908 healthy nullipara with singleton pregnancy and cephalic presentation who was in term labor in Beijing Obstetrics and Gynecology Hospital from August 1(st), 2014 to September 30(th), 2015 were recruited. They were divided into two groups, the vaginal delivery group (92.88%, 6 416/6 908) and the emergency cesarean section group (7.12%, 492/6 908)...
November 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29176767/h1n1-influenza-virus-infection-results-in-adverse-pregnancy-outcomes-by-disrupting-tissue-specific-hormonal-regulation
#9
Elizabeth Q Littauer, E Stein Esser, Olivia Q Antao, Elena V Vassilieva, Richard W Compans, Ioanna Skountzou
Increased susceptibility to influenza virus infection during pregnancy has been attributed to immunological changes occurring before and during gestation in order to "tolerate" the developing fetus. These systemic changes are most often characterized by a suppression of cell-mediated immunity and elevation of humoral immune responses referred to as the Th1-Th2 shift. However, the underlying mechanisms which increase pregnant mothers' risk following influenza virus infection have not been fully elucidated. We used pregnant BALB/c mice during mid- to late gestation to determine the impact of a sub-lethal infection with A/Brisbane/59/07 H1N1 seasonal influenza virus on completion of gestation...
November 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29153674/labor-therapeutics-and-bmi-as-risk-factors-for-postpartum-preeclampsia-a-case-control-study
#10
Geraldine Skurnik, Shelley Hurwitz, Thomas F McElrath, Lawrence C Tsen, Stacey Duey, Aditi R Saxena, Ananth Karumanchi, Janet W Rich-Edwards, Ellen W Seely
OBJECTIVES: This study aims at identifying associations between therapeutics used during labor and the occurrence of postpartum preeclampsia (PPPE), a poorly understood entity. STUDY DESIGN AND MAIN OUTCOME MEASURES: This is a case-control study of women who received an ICD-9 code for PPPE (cases) during the years 2009-2011, compared to women with a normotensive term pregnancy, delivery and postpartum period until discharge (controls), matched on age (±1year) and delivery date (±3months)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/28970134/a-comparison-of-the-effects-of-lindane-and-fecl3-adp-on-spontaneous-contractions-in-isolated-rat-or-human-term-myometrium
#11
Rebecca A Fanning, Deirdre P Campion, Maeve O'Shea, Michael F Carey, John J O'Connor
Oxidative stress affects the contractile behavior of smooth muscle resulting in complications during labor. Toxicants such as lindane and ferric chloride (FeCl3)/adenosine diphosphate (ADP) cause oxidative stress and have previously been shown to inhibit smooth muscle contraction. In this study we examined the effects of the oxygen species scavengers, ascorbic acid and N-acetylcysteine on lindane and FeCl3/ADP's inhibition of spontaneous myometrial contractions in rat and human myometrium. Lindane and FeCl3/ADP gave rise to concentration-dependent reductions in rat (EC50 11...
September 29, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28931404/a-cluster-randomized-trial-to-reduce-major-perinatal-morbidity-among-women-with-one-prior-cesarean-delivery-in-qu%C3%A3-bec-prisma-trial-study-protocol-for-a-randomized-controlled-trial
#12
N Chaillet, E Bujold, B Masse, W A Grobman, P Rozenberg, J C Pasquier, A Shorten, M Johri, F Beaudoin, H Abenhaim, S Demers, W Fraser, M Dugas, S Blouin, E Dubé, R Gauthier
BACKGROUND: Rates of cesarean delivery are continuously increasing in industrialized countries, with repeated cesarean accounting for about a third of all cesareans. Women who have undergone a first cesarean are facing a difficult choice for their next pregnancy, i.e.: (1) to plan for a second cesarean delivery, associated with higher risk of maternal complications than vaginal delivery; or (b) to have a trial of labor (TOL) with the aim to achieve a vaginal birth after cesarean (VBAC) and to accept a significant, but rare, risk of uterine rupture and its related maternal and neonatal complications...
September 20, 2017: Trials
https://www.readbyqxmd.com/read/28832100/consensus-on-use-of-insulins-in-gestational-diabetes
#13
Kalyan Kumar Gangopadhyay, J J Mukherjee, R K Sahay
INTRODUCTION: Gestational Diabetes Mellitus (GDM), diabetes diagnosed during pregnancy is associated with maternal (caesarean delivery, hypoglycaemia, hyperbilirubinaemia, shoulder dystocia, pre-term delivery and birth trauma) and fetal (Hyperbilirubinaemia in offspring, Neonatal hypoglycaemia, Macrosomia) complications. Despite, insulin being the standard treatment for GDM cases, there is no existing comprehensive consensus update on use of insulin in Indian patients with GDM. OBJECTIVE: To provide simple and easily implementable guidelines to healthcare physicians on use of insulin in GDM...
March 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28819943/the-mmp-9-timp-1-imbalance-and-the-reduced-level-of-tgf-%C3%AE-in-the-cervical-area-of-amniotic-membrane-is-a-possible-risk-factor-of-prom-and-premature-labor-proof-of-concept-study
#14
Małgorzata Litwiniuk, Małgorzata Radowicka, Alicja Krejner, Mirosław Wielgoś, Tomasz Grzela
OBJECTIVES: To assess the level MMP-9, TIMP-1 and TGF-β in placental and cervical region of amniotic membranes derived from at-term, pre-term and PROM deliveries. MATERIAL AND METHODS: 14 amniotic membranes have been assessed; the quantitative analysis of MMP-9, TGF-β and TIMP-1 was assayed using respective Quantikine Immunoassay Kit. RESULTS: The MMP-9 level in PROM samples was similar to the level of MMP-9 in at-term membranes and comparable between the cervical and placental region of these membranes...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28797150/-expression-of-peroxisome-proliferator-activated-receptors-fatty-acid-binding-protein-4-in-placenta-and-their-correlations-with-the-prognosis-of-pre-eclampsia
#15
Y Li, W L Chen, L Liu, H Gu
Objective: To examine the mRNA and protein expression of peroxisome proliferator-activated receptors (PPAR) and fatty acid binding protein-4 (FABP-4) in placenta, and to investigate their correlation with the prognosis of pre-eclampsia. Methods: The data of 177 women who delivered from January 2013 to December 2015 in Chinese People's Liberation Army No.94 Hospital were collected. Among them, 60 cases were term pregnancy and not in labor (TN); 46 cases were term pregnancy with preeclampsia and not in labor (TPE); 42 cases were preterm pregnancy and not in labor (PN); 29 cases were preterm pregnancy with pre-eclampsia and not in labor (PPE)...
July 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28757105/-double-balloon-catheter-compared-to-vaginal-dinoprostone-for-cervical-ripening-in-obese-women-at-term
#16
J Grange, J Dimet, M Vital, A Le Thuaut, G Ducarme
OBJECTIVE: To compare the efficacy of a double-balloon catheter versus vaginal prostaglandin E2 (dinoprostone) for cervical ripening in obese patients with unfavorable cervix at term. METHODS: The study had an open-label, prospective combined with retrospective, observational design. From January 2013 until May 2016, a prospective cohort study of 46 women with pre-pregnancy BMI>30kg/m(2), live singleton term fetuses (>37 weeks) in vertex presentation and unfavorable cervix (Bishop score<6), who underwent labor induction for conventional indications using a double-balloon catheter...
July 27, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28727132/analysis-of-intravaginal-misoprostol-0-2-mg-versus-intracervical-dinoprostone-0-5-mg-doses-for-labor-induction-at-term-pregnancies
#17
Teresa Górnisiewicz, Andrzej Jaworowski, Małgorzata Zembala-Szczerba, Dorota Babczyk, Hubert Huras
OBJECTIVES: Labor-induction methods are used in about 23% of labors. Most commonly, pharmacological methods are used to pre-induct the labor with dinoprostone - a PGE2 analog, and misoprostol - a PGE1 analog. The aim of this study was to evaluate two pharmacological methods of labor induction with the use of prostaglandins applied via an intravagi-nal insert containing misoprostol at a dose of 0.2 mg and intracervical gel containing dinoprostone at a dose of 0.5 mg. MATERIAL AND METHODS: This retrospective study was conducted on a group of 50 adult patients qualified for the pre-induction of labor...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28723278/a-case-of-cannabinoid-hyperemesis-syndrome-with-heliobacter-pylori-and-preeclampsia-during-pregnancy
#18
Madeline Manning Meurer, Kalyan Chakrala, Dinesh Gowda, Charles Burns, Randall Kelly, Natalia Schlabritz-Loutsevitch
BACKGROUND: The condition termed cannabinoid hyperemesis syndrome (CHS) was characterized a decade ago by Allen et al. and includes cyclic episodes of nausea and vomiting and the learned behavior of hot bathing in individuals with chronic cannabis abuse. During pregnancy, the differential diagnosis of this syndrome is challenging, since it can be masked by typical symptoms of early pregnancy or by hyperemesis gravidarum, a complication of early pregnancy associated with excessive nausea and vomiting...
July 19, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28720399/prenatal-and-postnatal-administration-of-prebiotics-and-probiotics
#19
REVIEW
Kristin Sohn, Mark A Underwood
Colonization of the neonatal gut by beneficial bacteria is important for the establishment and maintenance of the mucosal barrier, thus protecting the neonate from enteric pathogens and local and systemic inflammation. The neonatal microbiome is influenced by infant diet, environment, and the maternal microbiome. Dysbiosis in pregnancy increases the risk of pre-eclampsia, diabetes, infection, preterm labor, and later childhood atopy. Dysbiosis of the neonatal gut plays an important role in colic in the term infant, in the disease processes which plague preterm infants, including necrotizing enterocolitis and sepsis, and in the long-term outcomes of neonates...
October 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28699378/reasons-for-cesarean-and-medically-indicated-deliveries-in-pregnancies-in-women-with-systemic-lupus-erythematosus
#20
A M Eudy, M Jayasundara, T Haroun, L Neil, A H James, M E B Clowse
Objective To determine reasons for cesarean and medically indicated deliveries in a registry of pregnant women with SLE compared to RA. Methods Pregnant women with SLE or RA were prospectively followed, and pregnancy outcomes were collected, including whether labor was spontaneous or medically indicated and delivery was vaginal or cesarean. Preterm birth was defined as a birth <37 weeks gestation. Differences in reasons for cesarean delivery and indication of delivery between term and preterm births were determined by Fisher's exact test...
January 1, 2017: Lupus
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