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https://www.readbyqxmd.com/read/29668036/optimization-of-extraction-of-hypoglycemic-ingredients-from-grape-seeds-and-evaluation-of-%C3%AE-glucosidase-and-%C3%AE-amylase-inhibitory-effects-in-vitro
#1
Fansheng Kong, Yaru Qin, Zhipeng Su, Zhengxiang Ning, Shujuan Yu
Grape seeds full with oil and also rich in hypoglycemic ingredients. This study is to improve the comprehensive utilization of grape seeds and the quality of grape seeds oil. Extract water soluble active substances before extracting oil from grape seeds, which show the grape seeds in water soluble extracts containing TP, TC, PC contents, respectively, are 171.1 ± 1.1, 658.8 ± 0.2, 482.3 ± 0.2 (mg GSAE/g). Also we found GSAE samples containing catechin and epicatechin were 44.12 ± 0.21 mg/mL, 111.23 ± 1...
April 18, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29668030/uv-c-irradiation-on-the-quality-of-green-tea-effect-on-catechins-antioxidant-activity-and-cytotoxicity
#2
Matthew J Vergne, Ankit Patras, Manreet S Bhullar, Lincoln M Shade, Michael Sasges, Kanyasiri Rakariyatham, Che Pan, Hang Xiao
Short-wavelength ultraviolet (UV-C) irradiation is a nonthermal processing technique that is a possible alternative to the heat-pasteurization of tea beverages. This study investigated the effect of UV-C irradiation on the polyphenolic and total phenolic contents of a green tea beverage and analyzed cytotoxicity of irradiated green tea using a novel continuous flow-through UV system. UV-C fluence levels ranging from 0 to 240 mJ/cm2 were delivered to green tea, and polyphenols were chemically profiled. Continuous-flow UV-C irradiation of the green tea beverage at a fluence of 68 mJ/cm2  induced a minor reduction in the concentration of the most abundant catechin in green tea, (-)-epigallocatechin gallate (EGCG), from 145 to 131...
April 18, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29667548/flavonoids-and-platelet-derived-thrombotic-disorders
#3
Jose J Lopez, Mohammed El Haouari, Isaac Jardin, Nieves Alonso, Sergio Regodon, Raquel Diez Bello, Pedro Cosme Redondo, Juan A Rosado
Thrombotic disorders are characterized by an increase in the probability of the formation of unnecessary thrombi that might be due to the activation of the coagulation cascade or the circulating platelets. Platelets or thrombocytes play an essential role in hemostasis but abnormal platelet function leads to the development of a number of cardiovascular complications, including thrombotic disorders. Under pathological conditions, platelets are associated with the development of different thrombotic disorders, including atherosclerosis, arterial thrombosis and stroke, deep venous thrombosis and pulmonary embolism; therefore, platelets are the target of a number of anti-thrombotic strategies...
April 17, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29666514/taste-characteristics-of-chinese-bayberry-juice-characterized-by-sensory-evaluation-chromatography-analysis-and-an-electronic-tongue
#4
Haiyan Yu, Yan Zhang, Jie Zhao, Huaixiang Tian
To evaluate the taste characteristics of Chinese bayberry juice, four types of bayberry juice sourced from different origins and varieties were analysed using sensory evaluation, chromatography, spectroscopy analysis and an electronic tongue (E-tongue). Nine organic acids and three sugars were assessed using high performance liquid chromatography. Total polyphenols were measured by spectrophotometry. The overall taste profile was collected using the E-tongue. The four types of bayberry juice differed in the sensory attributes of sour, sweet, bitter, and astringent...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29665407/3-4-dihydroxybenzaldehyde-quenches-ros-and-rns-and-protects-human-blood-cells-from-cr-vi-induced-cytotoxicity-and-genotoxicity
#5
Nazim Husain, Riaz Mahmood
Hexavalent chromium [Cr(VI)] is the most toxic and potent form of chromium and induces multiple organ damage in humans and experimental animals. Oxidative stress has been implicated in the toxicity of Cr(VI). We have examined the potential role of 3,4-dihydroxybenzaldehyde (DHB), a plant polyphenolic antioxidant, in protecting human erythrocytes and lymphocytes from Cr(VI)-induced cytotoxicity and genotoxicity. Erythrocytes were treated with potassium dichromate, a Cr(VI) compound, in presence and absence of DHB...
April 14, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29663876/phytochemical-screening-antiproliferative-and-antioxidant-properties-of-various-extracts-from-endemic-origanum-acutidens
#6
Feyza Oke-Altuntas, Mehmet Ali Demirci, Ibrahim Demirtas, Ayse Sahin Yaglioglu, Lutfi Behcet
AIM AND OBJECTIVE: Origanum acutidens (Hand.-Mazz.) Ietsw. is an endemic and perennial plant grown mainly in East Anatolia. Recently, natural plant products have attracted interest due to their safety and therapeutic effects. Therefore, the aim of this study was to investigate phytochemical contents and biological effects of Origanum acutidens. MATERIALS AND METHODS: The aerial parts of O. acutidens were extracted with water, ethyl acetate, n-butanol, and methanol/chloroform solvents...
April 16, 2018: Combinatorial Chemistry & High Throughput Screening
https://www.readbyqxmd.com/read/29663499/resveratrol-inhibits-the-proliferation-and-induces-the-apoptosis-in-ovarian-cancer-cells-via-inhibiting-glycolysis-and-targeting-ampk-mtor-signaling-pathway
#7
Yu Liu, Lin Tong, Yan Luo, Xin Li, Gaowen Chen, Yifeng Wang
Aerobic glycolysis is an important metabolic rewiring in cancer cells to promote glucose uptake and lactate production, and targeting aerobic glycolysis becomes a promising therapeutic approach for cancer. Here we reported that a small polyphenol resveratrol exhibited profound anti-tumor efficacy on human ovarian cancer. Resveratrol markedly inhibited the proliferation, migration, and invasion of A2780 and SKOV3 ovarian cancer cells, while impaired glycolysis, and induced apoptosis in these cells. Exposure to resveratrol increased the expression and activation of AMPK and Caspase 3, and decreased the expression and activation of AMPK downstream kinase mTOR...
April 16, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29663159/evaluation-of-the-effect-of-polyphenol-of-escin-compared-with-ibuprofen-and-dexamethasone-in-synoviocyte-model-for-osteoarthritis-an-in-vitro-study
#8
Hossein Maghsoudi, Jamal Hallajzadeh, Mozhghan Rezaeipour
Osteoarthritis (OA) is a chronic degenerative joint disease with inflammatory component. It is associated with progressive histological alterations and disabling symptoms. Today, drugs such as glucocorticoids (GCs) and nonsteroidal anti-inflammatory drugs (NSIADs) are commonly employed for treatment of osteoarthritis, but have serious and life-threatening side effects. The aim of the current study is to evaluate the effects of escin on cyclooxygenase-2 (COX-2, isoform), inducible nitric oxide synthase (iNOS), interleukin-1β (IL-1β), interleukin-18 (IL-18), tumor necrosis factor-alpha (TNF-α), and nitric oxide (NO) (1), as well as prostaglandin E2 (PGE2) on inflammatory cells, similar osteoarthritis in synoviocytes, and monocytes/macrophages, and to compare it with dexamethasone (DEX) and ibuprofen (IBP)...
April 16, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29662848/cooking-characteristics-and-antioxidant-activity-of-rice-barley-mix-at-different-cooking-method-and-mixing-ratio
#9
Koan Sik Woo, Hyun-Joo Kim, Ji Hae Lee, Jee Yeon Ko, Byong Won Lee, Byoung Kyu Lee
This study aimed to compare the phenolic compounds and antioxidant activity of barley at different proportion (0, 5, 10, 15, and 20%), and using different cooking methods. The grains used in this experiment are barley ( Hordeum vulgare L. cv. Huinchalssal) and Samkwang rice. The rice-barley mixture was cooked using general and high pressure cooking methods with and without fermented alcohol. The quality characteristics such as water binding capacity, pasting characteristic, water solubility, and swelling power of different proportions of barley were evaluated...
March 2018: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29662845/suppressive-effects-of-vaccinium-angustifolium-root-extract-via-down-regulation-of-activation-of-syk-lyn-and-nf-%C3%AE%C2%BAb-in-fc%C3%A9-ri-mediated-allergic-reactions
#10
Sun-Yup Shim
Vaccinium angustifolium , reported as the lowbush blueberry, has a rich polyphenolic content with which biological activities have been closely associated. In this study, the effects of V. angustifolium root extract (VAE) on the anti-FcɛRI α chain antibody (CRA-1)-induced FcɛRI-mediated signaling factors, protein tyrosine kinases (PTK), Lyn, Syk, and nuclear factor kappa-B cells (NF-κB) in KU812F cells were investigated. The total phenolic content of VAE was found to be 170±1.9 mg gallic acid equivalents/g...
March 2018: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29662844/mineral-elements-bio-accessibility-and-antioxidant-indices-of-blanched-basella-rubra-at-different-phases-of-in-vitro-gastrointestinal-digestion
#11
Sule Ola Salawu, Bukola Eugenia Olukemi, Ikuosho Charity Asikhia, Akintunde Afolabi Akindahunsi
The present investigation was designed to evaluate the mineral element bio-accessibility and antioxidant indices of blanched Basella rubra at different phases of simulated in vitro digestion (oral, gastric, and intestinal). The phenolic composition of processed vegetable was determined using high-performance liquid chromatography (HPLC)-diode-array detection method. Mineral composition, total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power (FRAP), and total antioxidant activity (TAA) of the in vitro digested blanched and raw vegetable were also determined...
March 2018: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29660942/the-role-of-the-gut-microbiota-in-the-metabolism-of-polyphenols-as-characterized-by-gnotobiotic-mice
#12
Giulio Maria Pasinetti, Risham Singh, Susan Westfall, Francis Herman, Jeremiah Faith, Lap Ho
A growing body of experimental data suggests that microbes in the gut influence behavior and can alter brain physiology and neurochemistry. Although promising, researchers are only starting to understand the potential of the gut microbiota for use in neurological disease. Recent evidence demonstrated that gastrointestinal activities are linked to mood disorders such as anxiety, depression, and most recently, cognitive functions in age-related neurodegenerative disorders. Studies from our group and others are uncovering new evidence suggesting that the gut microbiota plays a crucial role in the metabolism and bioavailability of certain dietary compounds and synthetic drugs...
April 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29660865/effect-of-genotype-and-crop-year-on-the-nutritional-value-of-walnut-virgin-oil-and-defatted-flour
#13
Adrián Rabadán, José E Pardo, Arturo Pardo-Giménez, Manuel Álvarez-Ortí
The present study analyses the health-promoting compounds of walnut oil and walnut defatted flour obtained using hydraulic pressing. To identify the cultivar effect, nine walnut varieties were harvested in the same plot for two years to control environmental and agricultural management effects on kernel chemical traits. Beyond the variability reported in the products obtained from the different cultivars analysed, the crop year showed a crucial effect in the nutritional value of walnut products. Specifically, the variability caused for the crop year in the concentration of oleic and linoleic acids, phytosterols, polyphenols, tocopherols, proteins and essential minerals (K, Mg, P, S, Cu, Fe, Mn, Mo, Ni) was greater that the reported for the genotype...
April 12, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29660828/storage-stability-of-dietary-nitrate-and-phenolic-compounds-in-beetroot-beta-vulgaris-and-arugula-eruca-sativa-juices
#14
Karen A Corleto, Jashbir Singh, G K Jayaprakasha, Bhimanagouda S Patil
Nitrate and polyphenols from the diet may enhance the production and bioavailability of nitric oxide, a radical signaling molecule critical for cardiovascular health. Understanding the stability of these bioactives in beetroot and arugula juices is important for their functions. In this study, the stability of nitrate and phenolics in beetroot and arugula juices was measured for 32 days at different temperatures (25, 4, -20, and -80 °C). The levels of nitrate were measured by reversed-phase HPLC and initial levels were found to be 4965...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29660809/prosopis-nigra-mesocarp-fine-flour-a-source-of-phytochemicals-with-potential-effect-on-enzymes-linked-to-metabolic-syndrome-oxidative-stress-and-inflammatory-process
#15
María J Pérez, Iris C Zampini, Maria R Alberto, María I Isla
This work is part of the search in native food matrices from arid regions of Argentina of interest to improve human health. Prosopis species are ethnic food resources in South America capable of growing in arid and semi-arid environments. This work was focused to determine the nutritional and phytochemical composition of Prosopis nigra fine flour and to evaluate its biological properties. Flour showed a high level of sucrose (30.35 g/100 g flour), fiber (6.34 g/100 g flour), polyphenols (0.45 g GAE/100 g flour), and minerals (potassium, calcium, and magnesium)...
April 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29660118/effects-of-high-power-ultrasound-on-microflora-enzymes-and-some-quality-attributes-of-a-strawberry-drink
#16
Liyi Chen, Xiufang Bi, Xiamin Cao, Lei Liu, Zhenming Che
BACKGROUND: The objective of the present work was to study the effect of high power ultrasound (HPU) on microflora, enzymes and some quality attributes of a strawberry drink and to provide a theoretical basis for strawberry drinks processing, which was conducive to the development of more nutritious and healthier strawberry drinks. RESULTS: Fresh strawberry drink was subjected to HPU treatment at 20 kHz (242 W cm-2 , 605 W cm-2 and 968 W cm-2 ) for 2, 4, 6, 8, 10 min in an ice bath...
April 16, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29659956/polyphenols-have-no-impact-on-endothelial-function-in-patients-with-obstructive-sleep-apnea-a-randomized-controlled-trial
#17
Wojciech Trzepizur, Vanessa Bironneau, Sylvain Recoquillon, Pascaline Priou, Nicole Meslier, Jean-François Hamel, Samir Henni, Astrid Darsonval, Khaled Messaoudi, Maria Carmen Martínez, Ramaroson Andriantsitohaina, Frédéric Gagnadoux
Background: Endothelial dysfunction, a pathophysiologic determinant of atherogenesis, has been found to occur in obstructive sleep apnea syndrome (OSA) and is improved by continuous positive airway pressure (CPAP). However, the efficacy of CPAP therapy is limited by variable adherence. Alternative treatment strategies are needed. The impact of polyphenols on endothelial function has never been evaluated in OSA. Objective: We evaluated the impact of 1-mo supplementation with grape juice polyphenols (GJPs) on the reactive hyperemia index (RHI), a validated measure of endothelial function in patients with severe OSA...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29659685/can-curcumin-counteract-cognitive-decline-clinical-trial-evidence-and-rationale-for-combining-%C3%AF-3-fatty-acids-with-curcumin
#18
Julia Christina Kuszewski, Rachel Heloise Xiwen Wong, Peter Ranald Charles Howe
The rate of cognitive decline in the elderly is highly variable. One potential factor contributing to accelerated cognitive decline is chronic systemic inflammation, because it has been linked to cognitive impairment and increased dementia risk. Certain lifestyle factors, such as excess body weight and sedentary behavior, can exacerbate a proinflammatory state in older adults, resulting in chronic low-grade inflammation. Supplementing the diet with curcumin, an anti-inflammatory polyphenolic compound from the curry spice turmeric, is a potential approach to prevent accelerated cognitive decline by counteracting chronic inflammatory processes...
March 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29659550/use-of-olive-oil-industrial-by-product-for-pasta-enrichment
#19
Lucia Padalino, Isabella D'Antuono, Miriana Durante, Amalia Conte, Angela Cardinali, Vito Linsalata, Giovanni Mita, Antonio F Logrieco, Matteo Alessandro Del Nobile
BACKGROUND: During recent years food industries generally produce a large volume of wastes both solid and liquid, representing a disposal and potential environmental pollution problem. OBJECTIVE: The goal of the study was to optimize, from both sensory and nutritional points of view, the formulation of durum wheat spaghetti enriched with an olive oil industrial by-product, indicated as olive paste. METHODS: Three consecutive steps were carried out...
April 16, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29659549/blackcurrant-anthocyanins-increase-the-levels-of-collagen-elastin-and-hyaluronic-acid-in-human-skin-fibroblasts-and-ovariectomized-rats
#20
Naoki Nanashima, Kayo Horie, Hayato Maeda, Toshiko Tomisawa, Maiko Kitajima, Toshiya Nakamura
Blackcurrants ( Ribes nigrum L.) contain high levels of anthocyanin polyphenols, which have beneficial effects on health, owing to their antioxidant and anticarcinogenic properties. Phytoestrogens are plant-derived substances with estrogenic activity, which could have beneficial effects on the skin. Estradiol secretion decreases during menopause, reducing extracellular matrix (ECM) component production by skin fibroblasts. Using a normal human female skin fibroblast cell line (TIG113) and ovariectomized rats, the present study investigated whether an anthocyanin-rich blackcurrant extract (BCE) and four blackcurrant anthocyanins have novel phytoestrogenic activities that could benefit the skin in menopausal women...
April 16, 2018: Nutrients
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