keyword
MENU ▼
Read by QxMD icon Read
search

Developmental trauma

keyword
https://www.readbyqxmd.com/read/28331572/environmental-risk-factors-for-autism-an-evidence-based-review-of-systematic-reviews-and-meta-analyses
#1
REVIEW
Amirhossein Modabbernia, Eva Velthorst, Abraham Reichenberg
BACKGROUND: According to recent evidence, up to 40-50% of variance in autism spectrum disorder (ASD) liability might be determined by environmental factors. In the present paper, we conducted a review of systematic reviews and meta-analyses of environmental risk factors for ASD. We assessed each review for quality of evidence and provided a brief overview of putative mechanisms of environmental risk factors for ASD. FINDINGS: Current evidence suggests that several environmental factors including vaccination, maternal smoking, thimerosal exposure, and most likely assisted reproductive technologies are unrelated to risk of ASD...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28331499/qualitative-reflections-casa-s-trauma-and-attachment-group-tag-program-for-youth-who-have-experienced-early-developmental-trauma
#2
Chandra K Ashton, Anna O'Brien-Langer, Karin Olson, Peter H Silverstone
OBJECTIVE: We demonstrated previously that the Trauma and Attachment Group (TAG) program for youth in middle childhood significantly improved caregiver/child attachment relationships, reduced children's symptoms of attachment trauma, and increased the caregiver's ability for self-reflection. Here we examine the perspectives of both those administering and those taking part in this intensive dyad-based group intervention. METHODS: Utilizing an ethnographic design we collected and analyzed qualitative data obtained through a focus group and interviews with program facilitators, as well as interviews with participating caregivers...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28318055/menkes-disease-mimicking-child-abuse
#3
Rebecca J Droms, Jillian F Rork, Riley McLean, Madelena Martin, Leah Belazarian, Karen Wiss
Althouygh Menkes disease has well-recognized neurologic, developmental, and cutaneous features, the initial presentation may resemble child abuse. We describe a 5-month-old boy with multiple fractures indicative of nonaccidental trauma who was ultimately diagnosed with Menkes disease. Copper deficiency leads to connective tissue abnormalities and may result in subdural hematomas, wormian bones, cervical spine defects, rib fractures, and spurring of the long bone metaphyses. Several of these findings, including fractures and subdural hematomas, may be misinterpreted as child abuse...
March 20, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28300479/knowing-and-not-knowing-a-frequent-human-arrangement
#4
Sylvia Solinski
The paradigmatic system of societal abuse occurs in totalitarian state systems. The relational systems of subjugation that maintain such states of terror must, of necessity, destroy any authentic civic space in which individuals can flourish. Similar dynamics characterize child abuse within families. Survival requires the use of varied strategies, the most extreme of which are dissociative in nature, and that result in marked distortions of developmental trajectories across all psychological domains. Such dynamics are mirrored in dissociative systems that, in the absence of intervention, perpetuate the trauma of non-recognition by subjugation and self-objectification, or by omnipotent denial of others' subjectivity...
February 23, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28279865/post-traumatic-stress-as-a-pathway-to-psychopathology-among-adolescents-at-high-risk-for-victimization
#5
Kelly D Cromer, Miguel T Villodas
OBJECTIVE: Victimization by violence elevates adolescents' risk for developing internalizing and externalizing psychopathology. Recent findings suggest that disruptions in developmental processes associated with post-traumatic stress (PTS) reactions may partially account for the relationship between victimization and the subsequent development of psychopathology during adolescence. The present study tested the temporal sequencing of these associations using multi-informant measurements in a large, diverse sample of adolescents at high-risk for victimization...
March 6, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28261144/parallel-distinct-structures-of-internal-world-and-external-reality-disavowing-and-re-claiming-the-self-identity-in-the-aftermath-of-trauma-generated-dissociation
#6
Vedat Şar
The nature of consciousness and the autonomy of the individual's mind have been a focus of interest throughout the past century and inspired many theories and models. Revival of studies on psychological trauma and dissociation, which remained outside mainstream psychiatry, psychology, and psychoanalysis for the most part of the past century, has provided a new opportunity to revisit this intellectual and scientific endeavor. This paper attempts to integrate a series of empirical and theoretical studies on psychological consequences of developmental traumatization, which may yield further insight into factors which threaten the integrity of human consciousness...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28239630/from-attachment-to-independence-stress-hormone-control-of-ecologically-relevant-emergence-of-infants-responses-to-threat
#7
Adrienne Santiago, Chiye Aoki, Regina M Sullivan
Young infant rat pups learn to approach cues associated with pain rather than learning amygdala-dependent fear. This approach response is considered caregiver-seeking and ecologically relevant within the context of attachment. With maturation, increases in the stress hormone corticosterone permit amygdala-dependent fear, which is crucial for survival during independent living. During the developmental transition from attachment to fear learning, maternal presence suppresses corticosterone elevation to block amygdala-dependent fear learning and re-engage the attachment circuitry...
April 2017: Current Opinion in Behavioral Sciences
https://www.readbyqxmd.com/read/28235660/targeting-the-tlr4-signaling-pathway-by-polyphenols-a-novel-therapeutic-strategy-for-neuroinflammation
#8
REVIEW
Mahban Rahimifard, Faheem Maqbool, Shermineh Moeini-Nodeh, Kamal Niaz, Mohammad Abdollahi, Nady Braidy, Seyed Mohammad Nabavi, Seyed Fazel Nabavi
A wide array of cell signaling mediators and their interactions play vital roles in neuroinflammation associated with ischemia, brain trauma, developmental disorders and age-related neurodegeneration. Along with neurons, microglia and astrocytes are also affected by the inflammatory cascade by releasing pro-inflammatory cytokines, chemokines and reactive oxygen species. The release of pro-inflammatory mediators in response to neural dysfunction may be helpful, neutral or even deleterious to normal cellular survival...
February 21, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28216171/toward-a-unified-theory-of-childhood-trauma-and-psychosis-a-comprehensive-review-of-epidemiological-clinical-neuropsychological-and-biological-findings
#9
REVIEW
Błażej Misiak, Maja Krefft, Tomasz Bielawski, Ahmed A Moustafa, Maria M Sąsiadek, Dorota Frydecka
There is a growing body of research focused on the relationship between childhood trauma and the risk of developing psychosis. Numerous studies, including many large-scale population-based studies, controlling for possible mediating variables, provide persuasive evidence of a dose-response association and are indicative of a causal relationship. Existing evidence supports the specificity model, showing differential associations between particular adversities and clinical symptoms, with cumulative adversity causing less favorable clinical and functional outcomes in psychotic patients...
February 16, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28215878/neuroactive-steroids-and-ptsd-treatment
#10
REVIEW
Ann M Rasmusson, Christine E Marx, Suzanne L Pineles, Andrea Locci, Erica R Scioli-Salter, Yael I Nillni, Jennifer J Liang, Graziano Pinna
This review highlights early efforts to translate pre-clinical and clinical findings regarding the role of neuroactive steroids in stress adaptation and PTSD into new therapeutics for PTSD. Numerous studies have demonstrated PTSD-related alterations in resting levels or the reactivity of neuroactive steroids and their targets. These studies also have demonstrated substantial variability in the dysfunction of specific neuroactive steroid systems among PTSD subpopulations. These variabilities have been related to the developmental timing of trauma, severity and type of trauma, genetic background, sex, reproductive state, lifestyle influences such as substance use and exercise, and the presence of comorbid conditions such as depression and chronic pain...
February 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28199428/-complex-trauma
#11
María V Chiappe, Germán L Teti
The effects of trauma have been the focus of study by several researchers. However, at present, there is no diagnostic criteria that includes all forms of clinical presentations of subjects who have been victims of prolonged trauma or that have started at developmentally vulnerable times in the victim's life. Unlike those individuals who are victims of a single traumatic event, individuals who suffer multiple traumas that occur at vulnerable times, are at risk of developing a complex trauma. The concept of complex trauma was introduced in the last decades and is characterized by a symptomatic pleomorphism: emotional instability, somatization, dissociation; changes in identity, pathological changes in interpersonal relationships and suicidal behavior...
March 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28195013/betrayal-trauma-in-youth-and-negative-communication-during-a-stressful-task
#12
Vanessa M Jacoby, Elisa Krackow, Joseph R Scotti
Attachment-based theories and related research illustrate that emotion regulation develops in the context of a secure relationship between a child and caregiver. When a secure bond is broken, such as in the context of betrayal trauma, children fail to develop necessary emotion regulation skills which can lead to an array of relational problems. The current study examined the relations between betrayal trauma history, type of communication during a stressful interpersonal laboratory task, and emotion regulation difficulties in a sample of trauma-exposed adolescents...
March 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28193459/epileptiform-activity-and-behavioral-arrests-in-mice-overexpressing-the-calcium-channel-subunit-%C3%AE-2%C3%AE-1
#13
Leonardo C Faria, Feng Gu, Isabel Parada, Ben Barres, Z David Luo, David A Prince
The alpha2delta-1 subunit (α2δ-1) of voltage-gated calcium channels is a receptor for astrocyte-secreted thrombospondins that promote developmental synaptogenesis. Alpha2delta-1 receptors are upregulated in models of injury-induced peripheral pain and epileptogenic neocortical trauma associated with an enhancement of excitatory synaptic connectivity. These results lead to the hypothesis that overexpression of α2δ-1 alone in neocortex of uninjured transgenic (TG) mice might result in increased excitatory connectivity and consequent cortical hyperexcitability and epileptiform activity...
February 11, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28185206/what-you-don-t-know-can-hurt-you-the-risk-of-language-deprivation-by-impairing-sign-language-development-in-deaf-children
#14
Wyatte C Hall
A long-standing belief is that sign language interferes with spoken language development in deaf children, despite a chronic lack of evidence supporting this belief. This deserves discussion as poor life outcomes continue to be seen in the deaf population. This commentary synthesizes research outcomes with signing and non-signing children and highlights fully accessible language as a protective factor for healthy development. Brain changes associated with language deprivation may be misrepresented as sign language interfering with spoken language outcomes of cochlear implants...
February 9, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28179708/a-rare-congenital-liver-anomaly-hypoplasia-of-left-hepatic-lobe
#15
Tugrul Ormeci, Secil Telli Erdogan, Asli Ormeci, Cem Aygun
Morphologic anomalies of liver, as opposed to many other visceral organs, are very rare. Hypoplasia or agenesis of left lobe of the liver is defined as the absence of liver tissue on the left side of liver without previous disease or surgery. It is usually an incidental finding revealed by imaging exams or during abdominal surgery. A 44-year-old female patient was admitted to the hospital for abdominal pain and discomfort. Physical examination revealed no specific abnormality. Routine laboratory tests were normal...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28170306/evaluating-diagnostic-and-statistical-manual-of-mental-disorders-fifth-edition-posttraumatic-stress-disorder-diagnostic-criteria-in-older-children-and-adolescents
#16
Amy J Mikolajewski, Michael S Scheeringa, Carl F Weems
OBJECTIVES: Few studies have assessed how the diagnostic criteria for posttraumatic stress disorder (PTSD) apply to older children and adolescents. With the introduction of a new, developmentally sensitive set of criteria for very young children (age 6 years and younger) in Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), this raises new questions about the validity of the criteria for older children and adolescents. The current study investigated how diagnostic changes in DSM-5 impact diagnosis rates in 7-18-year olds...
February 7, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28167863/biomechanical-cell-regulatory-networks-as-complex-adaptive-systems-in-relation-to-cancer
#17
REVIEW
Liviu Feller, Razia Abdool Gafaar Khammissa, Johan Lemmer
Physiological structure and function of cells are maintained by ongoing complex dynamic adaptive processes in the intracellular molecular pathways controlling the overall profile of gene expression, and by genes in cellular gene regulatory circuits. Cytogenetic mutations and non-genetic factors such as chronic inflammation or repetitive trauma, intrinsic mechanical stresses within extracellular matrix may induce redirection of gene regulatory circuits with abnormal reactivation of embryonic developmental programmes which can now drive cell transformation and cancer initiation, and later cancer progression and metastasis...
2017: Cancer Cell International
https://www.readbyqxmd.com/read/28163912/the-benefits-of-youth-are-lost-on-the-young-cardiac-arrest-patient
#18
REVIEW
Brian Griffith, Patrick Kochanek, Cameron Dezfulian
Children and young adults tend to have reduced mortality and disability after acquired brain injuries such as trauma or stroke and across other disease processes seen in critical care medicine. However, after out-of-hospital cardiac arrest (OHCA), outcomes are remarkably similar across age groups. The consistent lack of witnessed arrests and a high incidence of asphyxial or respiratory etiology arrests among pediatric and young adult patients with OHCA account for a substantial portion of the difference in outcomes...
2017: F1000Research
https://www.readbyqxmd.com/read/28160586/eruption-cysts-a-series-of-66-cases-with-clinical-features
#19
E Şen-Tunç, H Açikel, I Şaroğlu-Sönmez, Ş Bayrak, N Tüloğlu
BACKGROUND: An eruption cyst (EC) is a benign, developmental cyst associated with a primary or permanent tooth. This paper presents 66 ECs in 53 patients who reported to 3 different centers in Turkey between 2014-2015. MATERIAL AND METHODS: 53 patients (31 male, 22 female) with 66 ECs were diagnosed and treated over a 1-year period. The mean age of patients was 5.4 years (minimum 5 months, maximum 11 years). Clinical examination and periapical radiographs were used to establish diagnosis...
March 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28153932/parental-engagement-and-early-interactions-with-preterm-infants-during-the-stay-in-the-neonatal-intensive-care-unit-protocol-of-a-mixed-method-and-longitudinal-study
#20
Alberto Stefana, Manuela Lavelli
INTRODUCTION: The preterm infants' developmental outcomes depend on biological and environmental risk factors. The environmental factors include prolonged parental separation, less exposure to early mother/father-infant interactions and the parents' ability to respond to the trauma of premature birth. In the case of premature birth, the father's ability to take an active part in the care of the infant from the start is essential. The parents' emotional closeness to the preterm infant hospitalised in the neonatal intensive care unit (NICU) may be crucial to the well-being of the newborn, the development of mutual regulation, the establishment of a functioning parent-infant affective relationship and the parents' confidence in their ability to provide care for their baby...
February 2, 2017: BMJ Open
keyword
keyword
34823
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"