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Developmental trauma

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https://www.readbyqxmd.com/read/29775876/childhood-abuse-and-depression-in-adulthood-the-mediating-role-of-allostatic-load
#1
Sandra Scheuer, Nicole Wiggert, Tanja Maria Brückl, Yvonne Awaloff, Manfred Uhr, Susanne Lucae, Stefan Kloiber, Florian Holsboer, Marcus Ising, Frank H Wilhelm
BACKGROUND: Traumatic experiences during childhood are considered a major risk factor for depression in adulthood. Childhood trauma may induce physiological dysregulation with long-term effects of increased allostatic load until adulthood, which may lead to depression. Thus, our aim was to investigate whether allostatic load - which represents a multi-system measure of physiological dysregulation - mediates the association between childhood trauma and adult depression. METHODS: The study sample consisted of 324 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project and 261 mentally healthy control participants...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29775870/adverse-and-adaptive-childhood-experiences-are-associated-with-parental-reflective-functioning-in-mothers-with-substance-use-disorder
#2
Ulrika Håkansson, Reidulf Watten, Kerstin Söderström, Finn Skårderud, Merete Glenne Øie
Mothers with a substance use disorder (SUD) are at risk for maladaptive parenting practices, and have heightened likelihood of having experienced childhood adversity themselves. In addition, parental reflective functioning (PRF), a capacity underlying sensitive caregiving, is often low in mothers with SUD. This study examines the relationship between PRF and aversive (emotional, physical, sexual abuse and neglect) and adaptive (safety and competence) experiences, in different developmental phases (early childhood, latency, and adolescence) in mothers with a SUD...
May 15, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29761341/the-prevalence-of-developmental-defects-of-enamel-a-prospective-cohort-study-of-adolescents-in-western-sweden-a-barn-i-tanadvarden-bita-children-in-dental-care-study
#3
B Jälevik, A Szigyarto-Matei, A Robertson
AIM: To describe the prevalence of different types of developmental defects of the enamel (DDE) in varying age-cohorts and habitations, and to analyse if early trauma to the primary teeth and early subsequent serious health problems were related to DDE in the permanent dentition. Dental fear and anxiety, and aesthetic problems as a consequence of DDE were also investigated. METHODS: DDE was registered over 5 years annually in three age cohorts (796 children). The DDE index (FDI Commision on Oral Health, Research and Epidemiology, Int Dent J 42:411-426, 1992) was used...
May 14, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29759022/compassion-focused-therapy-for-trauma-in-people-with-intellectual-disabilities-a-conceptual-review
#4
Megan Cowles, Cathy Randle-Phillips, Andrew Medley
Trauma exposure and post-traumatic stress disorder are more prevalent in people with intellectual disabilities (PWID) than in the general population, yet the evidence base for trauma interventions in this population is sparse. Compassion-focused therapy (CFT) may be particularly well-suited to PWID for a number of reasons, including its adaptability to different developmental levels. PWID are more likely to have issues with self-relating (e.g. shame and self-criticism) and attachment than the general population, two issues that are compounded by trauma and which CFT explicitly seeks to address...
January 1, 2018: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/29738289/tgf%C3%AE-3-msx1-and-mmp3-as-candidates-for-nscl%C3%A2-p-in-an-indian-population
#5
Priyanka Kumari, Subodh Kumar Singh, Rajiva Raman
OBJECTIVE: To evaluate the association of transforming growth factor β3 ( TGFβ3), muscle segment homeobox 1 ( MSX1), Metalloproteinases 3 ( MMP3), and MMP9 genes as candidates for nonsyndromic cleft lip and/or palate in an Indian population. DESIGN: Case-control association study, mutational screening, and functional evaluation of obtained mutations. SETTING: Mutational screening of the developmental genes, TGFβ3 and MSX1, along with functional evaluation and association of promoter region SNPs-one each in MMP3 and MMP9...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29733675/implications-of-attachment-theory-and-neuroscience-for-the-psychotherapeutic-treatment-of-obesity-and-overeating
#6
Fran Weiss
This article examines psychological sequelae underlying dysregulated eating in the overweight and obese patient and proposes a psychotherapy approach informed by classical and modern attachment theory, developmental trauma, and neuroscience to address these structural deficits.
May 7, 2018: American Journal of Psychotherapy
https://www.readbyqxmd.com/read/29689499/is-subthreshold-bipolar-ii-disorder-more-difficult-to-differentiate-from-borderline-personality-disorder-than-formal-bipolar-ii-disorder
#7
Adam Bayes, Rebecca K Graham, Gordon B Parker, Stacey McCraw
Recent research indicates that borderline personality disorder (BPD) can be diagnostically differentiated from the bipolar disorders. However, no studies have attempted to differentiate participants with sub-threshold bipolar disorder or SubT BP (where hypomanic episodes last less than 4 days) from those with a BPD. In this study, participants were assigned a SubT BP, bipolar II disorder (BP II) or BPD diagnosis based on clinical assessment and DSM-IV criteria. Participants completed self-report measures and undertook a clinical interview which collected socio-demographic information, a mood history, family history, developmental history, treatment information, and assessed cognitive, emotional and behavioural functioning...
April 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29683375/-developmental-trauma-disorder-dtd-in-children-and-adolescents-results-from-a-patient-population-at-the-special-consultation-hour-for-traumatized-children-and-adolescents
#8
Franka Metzner, Kristina Dahm, Hertha Richter-Appelt, Silke Pawils, Miriam Juliane Moulaa-Edmondson, Kerstin Stellermann-Strehlow
Objective: Children and adolescents who have experienced interpersonal Type-II-trauma often develop symptoms going far beyond the Post-Traumatic Stress Disorder (PTSD). Van der Kolk (2009) suggested the Developmental Trauma Disorder (DTD) to define the extensive symptomatology; however, research on DTD is limited. Method: Frequency and group differences of DTD were examined based on physicians’ letters of n = 161 patients between one and 18 years (61 % female) from an out-patient unit for traumatized patients at a paediatric and adolescent psychiatry...
April 23, 2018: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/29682226/surgical-approach-to-malformation-of-maxillary-central-incisor-following-trauma-to-its-predecessor-two-case-reports
#9
Gerardo La Monaca, Iole Vozza, Susanna Annibali, Rita Giardino, Nicola Pranno, Maria Paola Cristalli
In the case reports, two different approaches have been described to treat the developmental disturbances in the maxillary central incisors due to trauma to its predecessor. The treatment plan was chosen according to the type and severity of the malformations, the exact location and the morphology of the involved teeth. In the first case, the disimpaction of the maxillary right central incisor was achieved with the combined of surgical and orthodontic therapy, that was planned in two consecutive stages. In the second case the severe root angulation and the failure of the previous orthodontic traction made impossible the repositioning of the upper right central incisor, which was surgical removed...
September 2017: Annali di Stomatologia
https://www.readbyqxmd.com/read/29681251/behavior-problems-in-sexually-abused-preschoolers-over-a-1-year-period-the-mediating-role-of-attachment-representations
#10
Florence Charest, Martine Hébert, Annie Bernier, Rachel Langevin, Raphaële Miljkovitch
According to the developmental psychopathology framework, adverse childhood experiences, including child sexual abuse (CSA), may alter the course of normal development in children. Attachment security has been identified as a protective factor against psychopathology and may thus play a critical role in predicting victims' adaptation. The main objective of the present study was to investigate the mediating effect of attachment representations in the relation between CSA and behavior problems over a 1-year period...
April 23, 2018: Development and Psychopathology
https://www.readbyqxmd.com/read/29672100/childhood-trauma-pubertal-timing-and-cardiovascular-risk-in-adulthood
#11
Man-Kit Lei, Steven R H Beach, Ronald L Simons
OBJECTIVE: An association between childhood trauma and adult health outcomes has been widely reported, but little is known about the developmental pathways through which childhood trauma influences adult cardiovascular disease (CVD). METHOD: Hypotheses were tested with a sample of 405 African Americans from the Family and Community Health Study (FACHS). Path modeling was used to test our theoretical model. RESULTS: Replicating prior research, exposure to childhood trauma was associated positively with increases in symptoms of CVD risk across young adulthood even after controlling for a variety of health-related and health behavior covariates...
April 19, 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29661835/sexual-differentiation-of-contextual-fear-responses
#12
Lorianna Colon, Natalie Odynocki, Anthony Santarelli, Andrew M Poulos
Development and sex differentiation impart an organizational influence on the neuroanatomy and behavior of mammalian species. Prior studies suggest that brain regions associated with fear motivated defensive behavior undergo a protracted and sex-dependent development. Outside of adult animals, evidence for developmental sex differences in conditioned fear is sparse. Here, we examined in male and female Long-Evans rats how developmental age and sex affect the long-term retention and generalization of Pavlovian fear responses...
May 2018: Learning & Memory
https://www.readbyqxmd.com/read/29657515/trauma-informed-temporary-assistance-for-needy-families-tanf-a-randomized-controlled-trial-with-a-two-generation-impact
#13
Layla G Booshehri, Jerome Dugan, Falguni Patel, Sandra Bloom, Mariana Chilton
Temporary Assistance for Needy Families (TANF) has limited success in building self-sufficiency, and rarely addresses exposure to trauma as a barrier to employment. The objective of the Building Wealth and Health Network randomized controlled trial was to test effectiveness of financial empowerment combined with trauma-informed peer support against standard TANF programming. Through the method of single-blind randomization we assigned 103 caregivers of children under age six into three groups: control (standard TANF programming), partial (28-weeks financial education), and full (same as partial with simultaneous 28-weeks of trauma-informed peer support)...
2018: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/29651949/nerve-growth-factor-early-studies-and-recent-clinical-trials
#14
Maria Luisa Rocco, Marzia Soligo, Luigi Manni, Luigi Aloe
Since its discovery, nerve growth factor (NGF) has long occupied a critical role in developmental and adult neurobiology for its many important regulatory functions on the survival, growth and differentiation of nerve cells in the peripheral and central nervous system. NGF is the first discovered member of a family of neurotrophic factors, collectively indicated as neurotrophins, (which include brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin 4/5). NGF was discovered for its action on the survival and differentiation of selected populations of peripheral neurons...
April 11, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29651520/-surface-modifications-of-implants-part-2-clinical-application
#15
Marcus Jäger
The chemical composition, surface structure and topography of a biomaterial have an essential influence on the effects of an implant in the human body. In orthopedic and trauma surgery they make a relevant contribution to solve the current and future challenges. Particularly high are the requirements of permanent implants in bone. Besides material aging due to oxidation, implants are subjected to cyclic loading that leads to relevant biomechanical wear and abrasion. To date significant efforts have been made to minimize adverse implant-associated immunoreactions as well as the risk of periprosthetic infections...
April 12, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29643529/-retrospective-study-of-dental-treatment-under-general-anesthesia-of-62-disabled-children-and-adolescents
#16
N Wang, Y M Zhao
OBJECTIVE: To retrospectively figure out the oral health status, treatment and follow-ups after dental treatment under general anesthesia (DGA) of disabled children or adolescents. METHODS: Clinical data of disabled children or adolescents and normal children as control received DGA in the Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology from August 2008 to September 2015 were recorded, including: gender, birth date, treatment date, disability type, oral health status before treatment, treatment content and follow-ups (in 1 year)...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29626828/higher-concentration-of-interleukin-6-a-possible-link-between-major-depressive-disorder-and-childhood-abuse
#17
Ana Munjiza, Milutin Kostic, Danilo Pesic, Milan Gajic, Ivanka Markovic, Dusica Lecic Tosevski
Little is known about the correlation between IL-6 and childhood abuse and neglect which may be risk factors for the development of affective disorders in adulthood. The aim of this study was to analyze differences in serum concentrations of IL-6 between patients with major depressive disorder and healthy controls, and to investigate possible correlations with adverse childhood experiences. Peripheral venous blood samples were obtained from 64 patients who fulfilled DSM-IV-R criteria for a current major depressive episode without psychotic symptoms (MDD) and 53 healthy controls, matched for age and gender...
March 28, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29626785/men-s-experiences-of-early-life-trauma-and-pathways-into-long-term-homelessness
#18
Julia Woodhall-Melnik, James R Dunn, Stephen Svenson, Caroline Patterson, Flora I Matheson
Previous studies that have explored the association between childhood trauma and homelessness indicate that traumatic events can lead to survivor distrust of interpersonal relationships and institutions, prolonged homelessness and poor health and social outcomes. The majority of this literature relies on quantitative data and fails to investigate the personal experiences of childhood trauma that are found to impact housing status later in life. Semi-structured, qualitative interviews were conducted with 25 men living in an urban area in Ontario who had spent more than 30 consecutive nights in an emergency shelter over the course of their housing histories...
April 4, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29616497/malformed-vertebrae-a-clinical-and-imaging-review
#19
REVIEW
Apeksha Chaturvedi, Nina B Klionsky, Umakanthan Nadarajah, Abhishek Chaturvedi, Steven P Meyers
A variety of structural developmental anomalies affect the vertebral column. Malformed vertebrae can arise secondary to errors of vertebral formation, fusion and/or segmentation and developmental variation. Malformations can be simple with little or no clinical consequence, or complex with serious structural and neurologic implications. These anomalies can occasionally mimic acute trauma (bipartite atlas versus Jefferson fracture, butterfly vertebra versus burst fracture), or predispose the affected individual to myelopathy...
April 3, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29596008/psychotropic-medications-for-highly-vulnerable-children
#20
Jennifer L McLaren, Erin R Barnett, Milangel T Concepcion Zayas, Jonathan Lichtenstein, Stephanie C Acquilano, Lisa M Schwartz, Steven Woloshin, Robert E Drake
At least 20% of children in the U.S. are highly vulnerable because they lack healthcare and protection. Several factors produce vulnerability: trauma, disruptions of parenting, poverty, involvement in the juvenile justice and/or child welfare systems, residence in restrictive settings, and problems related to developmental disabilities. These children receive psychotropic medications at high rates, raising numerous concerns. Areas covered: The authors begin this review with a description of the population of highly vulnerable children...
April 2018: Expert Opinion on Pharmacotherapy
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