keyword
https://read.qxmd.com/read/38547217/factors-related-to-a-sense-of-economic-insecurity-among-older-adults-who-participate-in-social-activities
#1
JOURNAL ARTICLE
Yuriko Inoue, Hisae Nakatani, Ichie Ono, Xuxin Peng
Japan has the highest life expectancy worldwide. Older adults who experience economic insecurity may refrain from seeking medical consultation or using long-term care insurance, and these behaviors may increase the incidence and progression of frailty. This study conducted a cross-sectional survey to identify factors related to a sense of economic insecurity among older adults who participate in social activities, and identified support measures. In total, 1,351 older adults aged ≥65 years who had participated in social activities voluntarily completed an anonymous self-administered questionnaire...
2024: PloS One
https://read.qxmd.com/read/38547008/the-importance-of-individual-beliefs-in-assessing-treatment-efficacy
#2
JOURNAL ARTICLE
Luisa Fassi, Shachar Hochman, Zafiris J Daskalakis, Daniel M Blumberger, Roi Cohen Kadosh
In recent years, there has been debate about the effectiveness of treatments from different fields, such as neurostimulation, neurofeedback, brain training, and pharmacotherapy. This debate has been fuelled by contradictory and nuanced experimental findings. Notably, the effectiveness of a given treatment is commonly evaluated by comparing the effect of the active treatment versus the placebo on human health and/or behaviour. However, this approach neglects the individual's subjective experience of the type of treatment she or he received in establishing treatment efficacy...
March 28, 2024: ELife
https://read.qxmd.com/read/38546936/implications-of-vascular-depression-for-successful-cognitive-aging-in-hiv-disease
#3
JOURNAL ARTICLE
Andrea I Mustafa, Ilex Beltran-Najera, Darrian Evans, Alexandria Bartlett, Vonetta M Dotson, Steven Paul Woods
Although older adults with HIV are at high risk for mild neurocognitive disorders, a subset experience successful cognitive aging (SCA). HIV is associated with an increased risk of vascular depression (VasDep), which can affect cognitive and daily functioning. The current study examined whether VasDep impedes SCA among older adults with HIV. 136 persons with HIV aged 50 years and older were classified as either SCA+ (n = 37) or SCA- (n = 99) based on a battery of demographically adjusted neurocognitive tests and self-reported cognitive symptoms...
March 28, 2024: Journal of Neurovirology
https://read.qxmd.com/read/38546932/evaluation-of-the-relationship-between-fdg-pet-hypometabolism-and-retinal-layer-thickness-in-patients-with-alzheimer-s-disease
#4
JOURNAL ARTICLE
Demet Duman Sastim, Gulcin Elboga, Umut Elboga, Kivanc Gungor
We aimed to investigate the diagnostic value of Optical coherence tomography (OCT) in Alzheimer's disease (AD) and to assess the correlation between OCT and fluorodeoxyglucose (FDG)-positron emission tomography (PET) which shows high diagnostic agreement with findings from postmortem histopathology-the gold standard method. Patients who were diagnosed with AD-related dementia were selected for the study. Patients with a mini mental test (MMT) score between 18 and 23 were included in the study (n = 31)...
March 28, 2024: Acta Neurologica Belgica
https://read.qxmd.com/read/38546669/college-student-mental-health-psychiatric-risk-and-psychological-wellbeing
#5
JOURNAL ARTICLE
Paul G Nestor, Sara B Boodai, Keira O'Donovan, Victoria Choate Hasler, Richard Hunter
OBJECTIVE: To examine both psychiatric risk and psychological wellbeing in a college student sample drawn from a majority-minority university. PARTICIPANTS: 100 participants (42% White; 70 females), mean age, 21.22 years. METHODS: Univariate and multivariate analyses examined the relationship of psychiatric risk (Brief Symptom Inventory; BSI) and psychological wellbeing (Mental Health Continuum-Short Form; MHC-SF) with student stress, cognition, Adverse Childhood Experiences (ACEs) and a new Positive Childhood Experiences (PCEs) scale...
March 28, 2024: Journal of American College Health: J of ACH
https://read.qxmd.com/read/38546580/on-parrots-delay-of-gratification-executive-function-and-how-sometimes-we-do-the-best-we-can
#6
JOURNAL ARTICLE
Michael J Beran
Engaging executive functions provides an individual with the means to engage in cognitive control by adjusting to the environment and processing information in a way that leads to optimal outcomes. There are some claims that explicit training on certain executive functioning abilities provides benefits beyond the training tasks, but other studies indicate that this may not be true or may be limited based on age and other factors. This same mixed pattern has been reported with nonhuman species, where training or even experience in one specific area, like inhibition, sometimes leads to positive transfer in new but similar tasks that presumably also require executive functions...
February 2024: Journal of Comparative Psychology
https://read.qxmd.com/read/38545877/the-relationship-between-executive-functions-self-reflection-and-insight-across-adulthood
#7
JOURNAL ARTICLE
Yasemin Sohtorik İlkmen, Ezgi Soncu Büyükişcan
OBJECTIVE: Research suggests that executive functions and metacognitive abilities, including self-reflection and insight, may share underlying mechanisms since both rely on top-down cognitive processes and require self-regulation. However, these relationships have not been thoroughly examined by empirical research. The current study investigated the relationship between insight, self-reflection, and executive functions cross-sectionally across different stages of aging. METHODS: Participants were 1284 (655 men and 629 women) cognitively healthy community dwellers with an age range of 18-89 years (M = 47...
March 28, 2024: Experimental Aging Research
https://read.qxmd.com/read/38545863/advancing-clinical-development-for-neuronopathic-hunter-syndrome-through-a-quantitatively-driven-reverse-translation-framework
#8
JOURNAL ARTICLE
Robert D Latzman, Olivia Campagne, Meera E Modi, Marta Karas, C J Malanga, David A H Whiteman
A quantitatively-driven evaluation of existing clinical data and associated knowledge to accelerate drug discovery and development is a highly valuable approach across therapeutic areas, but remains underutilized. This is especially the case for rare diseases for which development is particularly challenging. The current work outlines an organizational framework to support a quantitatively-based reverse translation approach to clinical development. This approach was applied to characterize predictors of the trajectory of cognition in Hunter syndrome (Mucopolysaccharidosis Type II; MPS-II), a rare X-linked lysosomal storage disorder, highly heterogeneous in its course...
April 2024: Clinical and Translational Science
https://read.qxmd.com/read/38545769/corydalis-ternata-nakai-alleviates-cognitive-decline-in-alzheimer-s-disease-by-reducing-%C3%AE-amyloid-and-neuroinflammation
#9
JOURNAL ARTICLE
Bomi Lee, Myeong-Sang Yu, Jae Gwang Song, Hyang-Mi Lee, Hyung Wook Kim, Dokyun Na
Recently, natural herbs have gained increasing attention owing to their comparatively low toxicity levels and the abundance of historical medical documentation regarding their use. Nevertheless, owing to a lack of knowledge regarding these herbs and their compounds, attempts to find those that could be beneficial for treating diseases have often been ad hoc; thus, there is now a growing demand for an in silico method to identify beneficial herbs. In this study, we present a computational approach for identifying natural herbs specifically effective in treating cognitive decline in AD sufferers, which analyzes the similarities between herbal compounds and known drugs targeting AD-related proteins...
March 28, 2024: Rejuvenation Research
https://read.qxmd.com/read/38545687/adapting-cognitive-remediation-group-therapy-online-focus-groups-with-people-aging-with-hiv
#10
JOURNAL ARTICLE
Andrew D Eaton, Jenny Hui, Marvelous Muchenje, Taylor Kon, Kate Murzin, Soo Chan Carusone, Nuelle Novik, Adria Quigley, Kristina Kokorelias, Francisco Ibáñez-Carrasco
Cognitive health is a significant concern for people aging with HIV/AIDS. Psychosocial group therapies may help people aging with HIV who experience cognitive challenges cope with their symptoms. The COVID-19 pandemic revealed in-person group therapies need adaptation for technology-mediated delivery. Peer-led focus groups discussed adapting cognitive remediation group therapy (CRGT) as an online intervention. CRGT combines mindfulness-based stress reduction and brain training activities. Purposive sampling recruited people aging with HIV (40+) who self-identified cognitive concerns and resided in one of two Canadian provinces...
2024: Journal of the International Association of Providers of AIDS Care
https://read.qxmd.com/read/38545641/relationship-of-emotional-intelligence-and-capability-of-answering-higher-order-knowledge-question-in-physiology-among-first-year-medical-students
#11
JOURNAL ARTICLE
Himel Mondal, Shaikat Mondal, Amita Singh, Amita Kumari, Mohammed Jaffer Pinjar, Ayesha Juhi, Santanu Nath, Anup Kumar D Dhanvijay, Anita Kumari, Pratima Gupta
Emotional intelligence (EI) has a positive correlation with the academic performance of medical students. However, why there is a positive correlation needs further exploration. We hypothesized that the capability of answering higher-order knowledge questions (HOQs) is higher in students with higher EI. Hence, we assessed the correlation between EI and the capability of medical students to answer HOQs in Physiology. First-year undergraduate medical students (n = 124) from an Indian medical college were recruited as a convenient sample...
March 28, 2024: Advances in Physiology Education
https://read.qxmd.com/read/38545542/predicting-5-year-dementia-conversion-in-veterans-with-mild-cognitive-impairment
#12
JOURNAL ARTICLE
Chase Irwin, Donna Tjandra, Chengcheng Hu, Vinod Aggarwal, Amanda Lienau, Bruno Giordani, Jenna Wiens, Raymond Q Migrino
INTRODUCTION: Identifying mild cognitive impairment (MCI) patients at risk for dementia could facilitate early interventions. Using electronic health records (EHRs), we developed a model to predict MCI to all-cause dementia (ACD) conversion at 5 years. METHODS: Cox proportional hazards model was used to identify predictors of ACD conversion from EHR data in veterans with MCI. Model performance (area under the receiver operating characteristic curve [AUC] and Brier score) was evaluated on a held-out data subset...
2024: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://read.qxmd.com/read/38545323/a-pilot-study-of-longitudinal-changes-in-neurocognition-white-matter-hyperintensities-and-cortical-thickness-in-atrial-fibrillation-patients-following-catheter-ablation-vs-medical-management
#13
JOURNAL ARTICLE
Hannah Schwennesen, Jeffrey N Browndyke, Mary Cooter Wright, Marat Fudim, James P Daubert, Mark F Newman, Joseph P Mathew, Jonathan P Piccini
BACKGROUND: Cerebral microembolization and atrophy complicate atrial fibrillation (AF). OBJECTIVES: We aimed to compare changes in neuroimaging findings between AF patients treated with catheter ablation and those treated with medical therapy. METHODS: In this pilot study, we evaluated differences in the change in regional white matter hyperintensity burden (WMHb) and cognitive function from baseline to 6 weeks and 1 year in patients treated with AF ablation (n = 12) and patients treated with medical management alone (n = 11)...
February 2024: Heart rhythm O2
https://read.qxmd.com/read/38545178/value-of-neutrophil-to-lymphocyte-ratio-in-neuronal-intranuclear-inclusion-disease
#14
JOURNAL ARTICLE
Nan Du, Lei Bao, Jing Zhang, Xiaowen Li, Jin Tian, Man Xia, Wei Chen, Pinyi Zhu, XiuJuan Sun, Min Wang, Yihan Wu, Lin He, Yang Gao, Wen Sun, Zunsheng Zhang, Hao Chen
BACKGROUND AND OBJECTIVES: The neutrophil-to-lymphocyte ratio (NLR) is a widely recognized marker of inflammation in peripheral blood. However, its specific role in neuronal intranuclear inclusion disease (NIID) has not been reported. This study aims to investigate the relationship between NIID and NLR. METHODS: A multicenter database was collected, including 157 NIID patients from seven hospitals (The Affiliated Hospital of Xuzhou Medical University, Yantai Yuhuangding Hospital, Tengzhou Central People's Hospital,The Affiliated Brain Hospital of Nanjing Medical University, Liaocheng People's Hospital,The Second Hospital of Shandong University, Inner Mongolia People's Hospital, Xuanwu Hospital Capital Medical University,The First Affiliated Hospital of USTC), along with 157 age- and gender-matched healthy control subjects...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38545036/hippocampal-amide-proton-transfer-values-are-associated-with-cerebral-small-vessel-disease-imaging-markers-and-total-burden-a-community-based-cross-sectional-study
#15
JOURNAL ARTICLE
Ronghua Mu, Xiaoyan Qin, Wei Zheng, Peng Yang, Bingqin Huang, Xin Li, Fuzhen Liu, Kan Deng, Xiqi Zhu
BACKGROUND: Neurodegeneration has been suggested to be associated with cerebral small vessel disease (CSVD). The association between different CSVD imaging markers and the extent of neurodegeneration could be indirectly confirmed by examining the relationship between CSVD imaging markers and the hippocampal amide proton transfer (APT) values. The associations between hippocampal APT values with CSVD imaging markers and CSVD total load need to be further validated. The aim of this study was to investigate potential variations in hippocampal APT values among individuals with CSVD imaging markers and varying degrees of CSVD total burden...
March 15, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38544990/association-of-sleep-patterns-and-water-intake-with-cognitive-functions-in-adults-in-an-urban-environment
#16
JOURNAL ARTICLE
Shazia Qayyum, Samina Iltaf, Madiha Sajjad, Mashaal Azam
OBJECTIVES: To explore the behavior patterns of students and working adults regarding the duration and quality of sleep and water intake in an urban environment and to identify the relationship between nighttime sleep extent and water intake with mood and cognitive performance. METHODS: This was a descriptive correlational study conducted at Islamic International Medical College, Riphah University at the Pathology department from March to June 2022. A total of 160 participants with age range of 20 to 50 years completed a self-report questionnaire regarding sleep patterns, water intake, and perceptions of mood, concentration, and memory...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38544846/incidence-and-risk-factors-for-psychological-distress-in-adult-female-patients-with-breast-cancer-a-systematic-review-and-meta-analysis
#17
REVIEW
Lin Tao, Yuping Xiang, Xiaohong Zeng, Lan Fu, Junying Li, Hong Chen
INTRODUCTION: Cancer-related distress can be described as a complex and unpleasant combination of psychological (such as cognitive, behavioral, and emotional), social, and spiritual challenges that may impact an individual's ability to effectively cope with the physical symptoms of cancer and its treatment. Existing literature has confirmed psychological distress (PD) as an important sequela of breast cancer diagnosis and treatment. However, the incidence and risk factors for PD in adult female patients with breast cancer remain unclear; therefore, focusing on the PD of female breast cancer patients is meaningful, as they are at highest risk of contracting breast cancer, and might differ in their coping styles from men...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38544796/remote-digital-cognitive-assessment-reveals-cognitive-deficits-related-to-hippocampal-atrophy-in-autoimmune-limbic-encephalitis-a-cross-sectional-validation-study
#18
JOURNAL ARTICLE
Kengo Shibata, Bahaaeddin Attaallah, Xin-You Tai, William Trender, Peter J Hellyer, Adam Hampshire, Sarosh R Irani, Sanjay G Manohar, Masud Husain
BACKGROUND: Autoimmune limbic encephalitis (ALE) is a neurological disease characterised by inflammation of the limbic regions of the brain, mediated by pathogenic autoantibodies. Because cognitive deficits persist following acute treatment of ALE, the accurate assessment of long-term cognitive outcomes is important for clinical assessments and trials. However, evaluating cognition is costly and an unmet need exists for validated digital methods. METHODS: In this cross-sectional validation study, we investigated whether a remote digital platform could identify previously characterised cognitive impairments in patients with chronic ALE and whether digital metrics would correlate with standard neuropsychological assessment and hippocampal volume...
March 2024: EClinicalMedicine
https://read.qxmd.com/read/38544780/aging-effects-on-the-encoding-retrieval-flip-in-associative-memory-fmri-evidence-from-incidental-contingency-learning
#19
JOURNAL ARTICLE
Else Schneider, Marko Rajkovic, Rudolf Krug, Marco P Caviezel, Carolin F Reichert, Oliver Bieri, André Schmidt, Stefan Borgwardt, Thomas Leyhe, Christoph Linnemann, Annette B Brühl, Undine E Lang, Tobias Melcher
INTRODUCTION: Associative memory is arguably the most basic memory function and therein constitutes the foundation of all episodic and semantic memory processes. At the same time, the decline of associative memory represents a core feature of age-related cognitive decline in both, healthy and pathological (i.e., dementia-related) aging. The neural mechanisms underlying age-related impairments in associative memory are still not fully understood, especially regarding incidental (i.e., non-intentional) learning...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38544729/e-vita-study-protocol-eu-japan-virtual-coach-for-smart-aging
#20
JOURNAL ARTICLE
Roberta Bevilacqua, Vera Stara, Giulio Amabili, Arianna Margaritini, Marco Benadduci, Federico Barbarossa, Elvira Maranesi, Anne-Sophie Rigaud, Sébastien Dacunha, Cecilia Palmier, Johanna Moller, Ryan Browne, Toshimi Ogawa, Rainer Wieching
AIM: The aim of this study is to report a trial protocol for assessing the improvement of older adults' well-being, promoting active and healthy aging, and reducing the risks of social exclusion, using a virtual coach. BACKGROUND: Increased longevity brings with it reduced autonomy and independence, and it is therefore necessary to act with preventive measures that can promote active and healthy aging. With the development of technology, new tools have appeared, including virtual coaches, which can enable people to lead a healthy lifestyle by identifying individual needs and goals and providing personalized recommendations and advice...
2024: Frontiers in Public Health
keyword
keyword
34801
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.