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https://www.readbyqxmd.com/read/29475171/intrahepatic-splenosis-mimicking-hepatic-neoplasia
#1
Gabriel Neves Saad Teles, Paulo Eduardo Zerati Monteiro, Raphael Raphe
INTRODUCTION: Splenosis is defined as the heterotopic autoimplantation of splenic tissue following trauma to or surgery on the spleen. CLINICAL CASE: We present a case of an asymptomatic 73-year-old male in whom hypervascular lesions were detected during routine exams. The patient reported a history of carotid artery surgery and cholecystectomy; he had a laparotomy incision from childhood but was unaware of the reason for it. The patient exhibited slightly elevated carcinoembryonic antigen (CEA) levels...
February 17, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29475154/nursing-students-and-preceptors-experience-of-assessment-during-clinical-practice-a-multilevel-repeated-interview-study-of-student-preceptor-dyads
#2
Karen Johanne Ugland Vae, Maria Engström, Gunilla Mårtensson, Anna Löfmark
Nursing students' learning process during clinical practice is dependent on the quality of their assessment, and the feedback that is given, however an issue that is very little examined. The aim of this study was to investigate student-preceptor dyads and their experiences of mid-course discussions and final assessment. Data were collected through repeated semi-structured individual interviews with 13 dyads close in time to the assessment discussions, and were analyzed by searching for similarities and differences in their experiences...
November 29, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/29474344/concept-based-curricula-a-national-study-of-critical-concepts
#3
Jennifer A Brussow, Karin Roberts, Matthew Scaruto, Sheryl Sommer, Christine Mills
As nursing education struggles to address a rapidly changing health care system, overcrowded curricula, and an increased focus on clinical reasoning skills, many programs have adopted or transitioned to concept-based curricula (CBCs), which are structured around key concepts and exemplars. Despite CBC's promised benefits, the process of developing a CBC framework may pose a challenge to programs. To address this barrier, a national study was conducted to develop a representative list of concepts and exemplars...
February 22, 2018: Nurse Educator
https://www.readbyqxmd.com/read/29474322/validation-of-a-novel-molecular-host-response-assay-to-diagnose-infection-in-hospitalized-patients-admitted-to-the-icu-with-acute-respiratory-failure
#4
Maria E Koster-Brouwer, Diana M Verboom, Brendon P Scicluna, Kirsten van de Groep, Jos F Frencken, Davy Janssen, Rob Schuurman, Marcus J Schultz, Tom van der Poll, Marc J M Bonten, Olaf L Cremer
OBJECTIVES: Discrimination between infectious and noninfectious causes of acute respiratory failure is difficult in patients admitted to the ICU after a period of hospitalization. Using a novel biomarker test (SeptiCyte LAB), we aimed to distinguish between infection and inflammation in this population. DESIGN: Nested cohort study. SETTING: Two tertiary mixed ICUs in the Netherlands. PATIENTS: Hospitalized patients with acute respiratory failure requiring mechanical ventilation upon ICU admission from 2011 to 2013...
March 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29474234/simple-hysterectomy-for-residual-cervical-intraepithelial-neoplasm
#5
Liat Binyamin, Meirav Segev, Yoav Peled, Haim Krissi, Gad Sabah, Oded Raban, Ariella Jakobson-Setton, Avi Ben-Haroush, Ram Eitan
OBJECTIVE: Many patients undergo hysterectomy for the treatment of cervical dysplasia. Factors that correlate with residual high-grade squamous intraepithelial lesions (HGSIL) at hysterectomy are not clear. We set out to determine preoperative features that may predict residual disease for patients treated for cervical dysplasia. MATERIALS AND METHODS: A retrospective database was reviewed for women who underwent simple hysterectomy for HGSIL between 1990 and 2013...
February 23, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29474198/high-prevalence-of-antithyroid-antibodies-in-a-new-zealand-cohort-of-patients-with-systemic-sclerosis
#6
Kamal K Solanki, Mahmood Al-Majmuei, Douglas H N White
BACKGROUND: Autoimmune thyroid disease affects 1% of the general population, and autoimmune thyroid antibodies are noted in up to 15%. OBJECTIVE: We hypothesized systemic sclerosis (SSc) is associated with higher prevalence of antithyroglobulin (anti-Tg) and anti-thyroid peroxidase (anti-TPO) antibodies) to justify monitoring of thyroid function for earlier detection and treatment. METHODS: Waikato Hospital SSc clinic patients were prospectively tested for thyroid function tests and antithyroid antibodies (ATAs)...
February 15, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29474100/cervical-myelopathy-causing-numbness-and-paresthesias-in-lower-extremities-a-case-report-identifying-the-cause-of-a-false-positive-sharp-purser-test
#7
Cody J Mansfield
INTRODUCTION: The patient was referred to an outpatient physical therapy clinic for lumbar radiculopathy by a primary care physician and subsequently referred for imaging due to suspicion of cervical myelopathy. The case highlights the clinical reasoning of the physical therapist differentiating between lumbar stenosis, cervical myelopathy, and upper cervical instability. To the author's knowledge, this is the only case report in the literature to describe the mechanism that could underpin a false positive Sharp-Purser test (SPT)...
February 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29473815/incidence-of-symptomatic-tethered-spinal-cord-in-pediatric-patients-presenting-with-neurofibromatosis-types-1-and-2
#8
Carolyn S Quinsey, Katie Krause, Lissa C Baird, Christina M Sayama, Nathan R Selden
OBJECTIVE The relationship between a tethered cord (TC) and neurofibromatosis type 1 (NF1) and NF2 is not known. The purpose of this study was to define the incidence of TC in pediatric neurosurgical patients who present with NF. METHODS The authors performed a single-institution (tertiary care pediatric hospital) 10-year retrospective analysis of patients who were diagnosed with or who underwent surgery for a TC and/or NF. Clinical and radiological characteristics were analyzed, as was histopathology. RESULTS A total of 424 patients underwent surgery for a TC during the study period, and 67 patients with NF were seen in the pediatric neurosurgery clinic...
February 23, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29473737/optofluidic-sensor-for-inline-hemolysis-detection-on-whole-blood
#9
Chen Zhou, Mehdi Keshavarz Hedayati, Xiaolong Zhu, Frank Nielsen, Uriel Levy, Anders Kristensen
Hemolysis is the rupture of red blood cells and constitutes the most common reason for unsuitable blood samples in the clinic. To detect hemolysis, one has to separate the hemoglobin in blood plasma from that in red blood cells. However, current methods entail centrifugation for cell-plasma separation, which is complex, time-consuming, and not easy to integrate into point-of-care (PoC) systems. Here, we demonstrate an optofluidic sensor composed of nanofilters on an optical waveguide, which enables evanescent-wave absorption measurement of hemoglobin in plasma with the capability of real-time inline detection on whole blood without extra sample preparation like centrifugation...
February 23, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29473694/comparing-apples-and-oranges-and-pears-and-kumquats-the-misuse-of-index-systems-for-processing-histopathology-data-in-fish-toxicological-bioassays
#10
Jeffrey C Wolf
Histopathology index systems involve the application of weighted scores to various diagnostic findings for the purpose of calculating overall organ and/or whole animal health measurements. Such systems were originally developed as tools for monitoring the general health of fish populations. More recently, index systems have been applied to hypothesis-based toxicological studies, the goal of which is to investigate whether a cause-and-effect relationship exists between exposure to a particular test substance or environmental contaminant and morphologic effects in fish tissues...
February 23, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29473370/-the-design-and-application-of-a-moxibustion-instrument-with-less-harmful-smoke-and-direction-adjustment
#11
Hongliang Tang, Xiongjiang Wang, Zhangsong Nong, Kailong Wang, Jun Pang
The design of a clip-on moxibustion instrument which could adjust the directions and absorb harmful granules of moxa smoke was introduced in this paper. It was designed to solve the problems in home health care and clinical treatment, such as the inconvenience of adjustment of moxibustion directions and temperature, more dust and granules of moxa smoke and inconvenience of moxibustion placement. The main part of moxibustion instrument was made up of moxibustion box, bracket and base clamp. The moxibustion box could fix moxa stick and absorb smoke granules; the bracket could be twisted to adjust the direction of moxibustion box; the base clamp was aimed to fix moxibustion box on the edge of the object to save space...
February 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29472890/severe-blood-brain-barrier-disruption-in-cardioembolic-stroke
#12
Chang Liu, Feina Shi, Zhicai Chen, Shenqiang Yan, Xinfa Ding, Min Lou
Background: Previous studies demonstrated that cardioembolism (CE) was prone to develop hemorrhagic transformation (HT), whereas hyper-permeability of blood-brain barrier (BBB) might be one reason for the development of HT. We, thus, aimed to investigate whether the BBB permeability (BBBP) was higher in CE stroke than other stroke subtypes in acute ischemic stroke (AIS) patients. Methods: This study was a retrospective review of prospectively collected clinical and imaging database of AIS patients who underwent CT perfusion...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29472251/secondary-stroke-prevention-services-in-canada-a-cross-sectional-survey-and-geospatial-analysis-of-resources-capacity-and-geographic-access
#13
Lauren Jewett, Adil Harroud, Michael D Hill, Robert Côté, Theodore Wein, Eric E Smith, Gord Gubitz, Andrew M Demchuk, Demetrios J Sahlas, David J Gladstone, M Patrice Lindsay
BACKGROUND: Rapid assessment and management of transient ischemic attacks and nondisabling strokes by specialized stroke prevention services reduces the risk of recurrent stroke and improves outcomes. In Canada, with its vast geography and with 16.8% of the population living in rural areas, access to these services is challenging, and considerable variation in access to care exists. The purpose of this multiphase study was to identify sites across Canada providing stroke prevention services, evaluate resource capacity and determine geographic access for Canadians...
February 21, 2018: CMAJ Open
https://www.readbyqxmd.com/read/29472179/representation-of-time-relevant-common-data-elements-in-the-cancer-data-standards-repository-statistical-evaluation-of-an-ontological-approach
#14
Henry W Chen, Jingcheng Du, Hsing-Yi Song, Xiangyu Liu, Guoqian Jiang, Cui Tao
BACKGROUND: Today, there is an increasing need to centralize and standardize electronic health data within clinical research as the volume of data continues to balloon. Domain-specific common data elements (CDEs) are emerging as a standard approach to clinical research data capturing and reporting. Recent efforts to standardize clinical study CDEs have been of great benefit in facilitating data integration and data sharing. The importance of the temporal dimension of clinical research studies has been well recognized; however, very few studies have focused on the formal representation of temporal constraints and temporal relationships within clinical research data in the biomedical research community...
February 22, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29472008/efficacy-and-safety-of-alirocumab-in-high-risk-patients-with-clinical-atherosclerotic-cardiovascular-disease-and-or-heterozygous-familial-hypercholesterolemia-from-5-placebo-controlled-odyssey-trials
#15
Peter A McCullough, Christie M Ballantyne, Santosh K Sanganalmath, Gisle Langslet, Seth J Baum, Prediman K Shah, Andrew Koren, Jonas Mandel, Michael H Davidson
Patients with previous atherosclerotic cardiovascular disease (ASCVD) and/or heterozygous familial hypercholesterolemia (HeFH) are at high risk of future cardiovascular events. Despite maximally tolerated doses of statins, many patients still have elevated low-density lipoprotein cholesterol (LDL-C) levels. We evaluated the efficacy and safety of alirocumab in patients with ASCVD and/or HeFH on a maximally tolerated dose of statin (rosuvastatin 20 or 40 mg, atorvastatin 40 or 80 mg, or simvastatin 80 mg, or lower doses with an investigator-approved reason) ± other lipid-lowering therapies from 5 placebo-controlled phase 3 trials (52 to 78 weeks)...
February 2, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29471960/overview-of-autosomal-dominant-polycystic-kidney-disease-in-the-south-of-spain
#16
Ana Isabel Morales García, Margarita Martínez Atienza, María García Valverde, Juan Fontes Jimenez, Antonio Martínez Morcillo, M Angustias Esteban de la Rosa, Pablo de Diego Fernández, Miguel García González, Rafael Fernández Castillo, Irene Argüelles Toledo, Juan Antonio Bravo Soto, Rafael Esteban de la Rosa
INTRODUCTION: Although autosomal dominant polycystic kidney disease is the most common hereditary kidney disease, available data tend to be limited to after initiation of renal replacement therapy. OBJECTIVE: To ascertain an overview of autosomal dominant polycystic kidney disease within the health area of Granada in southern Spain. MATERIAL AND METHODS: From January 2007 to December 2016, we collected clinical, family and demographic information about all patients with autosomal dominant polycystic kidney disease, irrespective of whether or not they were treated with RRT, in the Granada health area...
March 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29471904/completion-of-isoniazid-preventive-therapy-among-human-immunodeficiency-virus-positive-adults-in-urban-malawi
#17
D Thindwa, P MacPherson, A T Choko, M Khundi, R Sambakunsi, L G Ngwira, T Kalua, E L Webb, E L Corbett
SETTING: Despite worldwide scale-up of human immunodeficiency virus (HIV) care services, relatively few countries have implemented isoniazid preventive therapy (IPT). Among other programmatic concerns, IPT completion tends to be low, especially when not fully integrated into HIV care clinics. OBJECTIVE: To estimate non-completion of 6-month IPT and its predictors among HIV-positive adults aged 16 years. DESIGN: A prospective cohort study nested within a cluster-randomised trial of TB prevention was conducted between February 2012 and June 2014...
March 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29471903/estimating-the-magnitude-of-pulmonary-tuberculosis-patients-missed-by-primary-health-care-clinics-in-south-africa
#18
P F Kweza, C Van Schalkwyk, N Abraham, M Uys, M M Claassens, A Medina-Marino
SETTING: The present study was conducted at 20 randomly selected primary health clinics across Buffalo City Metropolitan Health District, a high TB burden district in South Africa. OBJECTIVE: To estimate the proportion of TB patients missed by primary health clinics. DESIGN: We enrolled 1255 TB-symptomatic individuals exiting primary health clinics between March and December 2015. Participants were interviewed and asked to provide sputum for Xpert® MTB/RIF testing...
March 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29471824/perceived-stress-reasons-for-and-sources-of-stress-among-medical-students-at-rabigh-medical-college-king-abdulaziz-university-jeddah-saudi-arabia
#19
Zohair Jamil Gazzaz, Mukhtiar Baig, Bader Salem Mana Al Alhendi, Mohammed Mahdi Owiad Al Suliman, Awshaemah Salem Al Alhendi, Mana Saleh Hadi Al-Grad, Mohammed Abdullah Ali Qurayshah
BACKGROUND: Medical students have high levels of stress that could be due to the daily life stressors and the extra stress of academic burden. The present study investigated the perceived stress level as well as the reasons and sources of stress among medical students at a comparatively newly established medical college affiliated with King Abdulaziz University (KAU), Jeddah, Saudi Arabia (SA). METHODS: The present study was carried out at Rabigh Medical College (RMC), KAU, Jeddah, and completed in 2015...
February 23, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29471749/comparing-mentorship-and-sponsorship-in-clinical-neuropsychology
#20
Robin C Hilsabeck
OBJECTIVE: Mentoring is a well-known concept that is widely regarded as beneficial for personal and professional development. The concept of sponsoring is less recognized although it is considered critical by some for career advancement. The purpose of this study was to provide an initial exploration of differences between mentoring and sponsoring within neuropsychology and to learn what sponsors look for in protégés. METHOD: Twenty neuropsychologists with experience in mentorship and sponsorship were interviewed...
February 2018: Clinical Neuropsychologist
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