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Diagnostic errors

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https://www.readbyqxmd.com/read/29329065/factors-associated-with-depression-among-homeless-mothers-results-of-the-enfams-survey
#1
M Roze, S Vandentorren, J Van-Der-Waerden, M Melchior
PURPOSE: Women are disproportionately likely to suffer from depression. This is especially true for those who experience socioeconomic hardship, such as homelessness. In France, among homeless mothers many are migrant. However, it is not clear whether risk factors associated with depression are specific for this group or the same as in the general population. Our objective was to describe socio-demographic, relational, living and housing conditions and health factors associated with depression among homeless mothers...
January 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29328164/impact-of-input-field-characteristics-on-vibrational-femtosecond-coherent-anti-stokes-raman-scattering-thermometry
#2
Chao-Bo Yang, Ping He, David Escofet-Martin, Jiang-Bo Peng, Rong-Wei Fan, Xin Yu, Derek Dunn-Rankin
In this paper, three ultrashort-pulse coherent anti-Stokes Raman scattering (CARS) thermometry approaches are summarized with a theoretical time-domain model. The difference between the approaches can be attributed to variations in the input field characteristics of the time-domain model. That is, all three approaches of ultrashort-pulse (CARS) thermometry can be simulated with the unified model by only changing the input fields features. As a specific example, the hybrid femtosecond/picosecond CARS is assessed for its use in combustion flow diagnostics; thus, the examination of the input field has an impact on thermometry focuses on vibrational hybrid femtosecond/picosecond CARS...
January 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29324775/the-optimal-threshold-of-serum-ceruloplasmin-in-the-diagnosis-of-wilson-s-disease-a-large-hospital-based-study
#3
Rong Xu, Yong-Fang Jiang, Yong-Hong Zhang, Xu Yang
BACKGROUND AND AIMS: A ceruloplasmin (CP) concentration <200 mg/L is conventionally considered as one of the major diagnostic criteria for Wilson's disease (WD). However, the diagnostic accuracy of this threshold has never been investigated in a sufficiently large group of patients. This study aims to present the results of serum CP measurements in various patients and to identify the optimal cutoff value of CP for the diagnosis of WD. MATERIALS AND METHODS: We identified patients whose CP levels were evaluated from January 1, 2016 to December 31, 2016 using a laboratory information database...
2018: PloS One
https://www.readbyqxmd.com/read/29322215/-assessment-of-kidney-function-creatinine-is-not-the-whole-story
#4
REVIEW
U Huynh-Do, M Fiedler, B Vogt
Chronic renal insufficiency has a high prevalence and leads not only to a severe impairment in the quality of life but also to a higher mortality, mainly due to cardiovascular complications; however, in the early stages where there is still a chance for a therapeutic intervention, it is often underestimated because depending on endogenous factors (e.g. age and muscle mass), serum creatinine could falsely remain in the normal range while kidney function is already impaired. An exact measurement of the glomerular filtration rate (GFR) using radionuclide techniques is cumbersome and usually confined to rare cases, such as in clinical studies...
January 10, 2018: Der Internist
https://www.readbyqxmd.com/read/29321613/evaluation-of-in-vivo-digital-root-reconstruction-based-on-anatomical-characteristics-of-the-periodontal-ligament-using-cone-beam-computed-tomography
#5
Chenxin Wang, Yi Liu, Siwei Wang, Yong Wang, Yijiao Zhao
This study's aim was to develop and validate an approach to automatically extract and reconstruct three-dimensional (3D) digital root models from in vivo teeth based on the anatomical characteristics of the periodontal ligament using cone beam computed tomography (CBCT) data. Prior to undergoing dental extractions for orthodontic purposes, the CBCT data of each study participant were collected and imported into Mimics software to reconstruct 3D in vivo digital root models (test models). Twenty roots of 17 teeth extracted from the study's participants were scanned using a dental scanner to obtain 3D in vitro digital root models (reference models)...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317377/multiparametric-mri-for-the-detection-of-local-recurrence-of-prostate-cancer-in-the-setting-of-biochemical-recurrence-after-low-dose-rate-brachytherapy
#6
Luca F Valle, Matthew D Greer, Joanna H Shih, Tristan Barrett, Yan Mee Law, Andrew B Rosenkrantz, Haytham Shebel, Akhil Muthigi, Daniel Su, Maria J Merino, Bradford J Wood, Peter A Pinto, Andra V Krauze, Aradhana Kaushal, Peter L Choyke, Barış Türkbey, Deborah E Citrin
PURPOSE: Prostate multiparametric magnetic resonance imaging (mpMRI) has utility in detecting post-radiotherapy local recurrence. We conducted a multireader study to evaluate the diagnostic performance of mpMRI for local recurrence after low dose rate (LDR) brachytherapy. METHODS: A total of 19 patients with biochemical recurrence after LDR brachytherapy underwent 3T endorectal coil mpMRI with T2-weighted imaging, dynamic contrast-enhanced imaging (DCE) and diffusion-weighted imaging (DWI) with pathologic confirmation...
January 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29316379/reactive-histiocytic-proliferation-in-the-pleural-fluid-mimicking-metastatic-signet-ring-adenocarcinoma
#7
Fatima Mir, Anam Naumaan, Hussein Alnajar, Arlen Brickman, Vijaya Reddy, Ji-Weon Park, Paolo Gattuso
Reactive nodular and diffuse histiocytic proliferations of mesothelial and non-mesothelial lined sites have been sporadically reported in the literature. However, there is no cytologic literature describing this process. We report a case of reactive histiocytic proliferation mimicking a metastatic signet ring adenocarcinoma in pleural fluid from a 33-year-old white male. Ancillary studies such as immunohistochemistry should be used to elucidate the cell of origin and avoid diagnostic errors.
January 8, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29314070/diagnostic-reliability-of-pretreatment-biopsy-in-malignant-nasoethmoidal-tumors-a-retrospective-study-of-77-cases
#8
Alberto Schreiber, Vittorio Rampinelli, Marco Ferrari, Davide Mattavelli, Davide Farina, Simonetta Battocchio, Piero Nicolai
OBJECTIVES/HYPOTHESIS: Pretreatment biopsy is crucial in histology-based management of malignant nasoethmoidal tumors, because misdiagnosis can lead to inadequate therapeutic planning. Factors influencing the reliability of biopsy were retrospectively investigated in a tertiary referral center. STUDY DESIGN: Retrospective case series. METHODS: All patients who underwent biopsy, staging magnetic resonance, surgery, and histologic diagnosis for nasoethmoidal tumors in our hospital were retrospectively evaluated...
January 4, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29314060/dynamic-field-of-view-imaging-to-increase-temporal-resolution-in-the-early-phase-of-contrast-media-uptake-in-breast-dce-mri-a-feasibility-study
#9
Federico D Pineda, Ty O Easley, Gregory S Karczmar
PURPOSE: To increase diagnostic accuracy of breast MRI by increasing temporal resolution and more accurately sampling the early kinetics of contrast media uptake. We tested the feasibility of accelerating bilateral breast DCE-MRI by reducing the FOV, allowing aliasing, and unfolding the resulting images. METHODS: Previous experience with an 'ultrafast' protocol for bilateral breast DCE-MRI (6s-10s temporal resolution) showed that the number of significantly enhancing voxels is very low in the first 30 to 45 seconds after contrast media injection...
January 3, 2018: Medical Physics
https://www.readbyqxmd.com/read/29306903/implementation-of-diagnostic-pauses-in-the-ambulatory-setting
#10
Grace C Huang, Gila Kriegel, Carolyn Wheaton, Scot Sternberg, Kenneth Sands, Jeremy Richards, Katherine Johnston, Mark Aronson
BACKGROUND: Diagnostic errors result in preventable morbidity and mortality. The outpatient setting may be at increased risk, where time constraints, the indolent nature of outpatient complaints and single decision-maker practice models predominate. METHODS: We developed a self-administered diagnostic pause to address diagnostic error. Clinicians (physicians and nurse practitioners) in an academic primary care setting received the tool if they were seeing urgent care patients who had previously been seen in the past two weeks in urgent care...
January 6, 2018: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29306382/diagnostic-radiographers-working-in-the-operating-theatre-an-action-research-project
#11
S Naylor, D Foulkes
INTRODUCTION: Failures in interprofessional communication are well-documented and are an established cause of medical error and negative health outcomes. Socio-historical issues like imbalances in power and status are particularly prevalent in the operating theatre environment, adding complications to interprofessional working. Simulation, used in healthcare education, may impact positively on interprofessional working. METHODS: The aim of this action research study was to develop, pilot and run a simulation experience for Diagnostic Radiography (DRAD) students...
February 2018: Radiography
https://www.readbyqxmd.com/read/29305546/multicenter-evaluation-of-the-accelerate-phenotest%C3%A2-bc-kit-for-rapid-identification-and-phenotypic-antimicrobial-susceptibility-testing-using-morphokinetic-cellular-analysis
#12
Preeti Pancholi, Karen C Carroll, Blake W Buchan, Raymond C Chan, Neelam Dhiman, Bradley Ford, Paul A Granato, Amanda T Harrington, Diana R Hernandez, Romney M Humphries, Matthew R Jindra, Nathan A Ledeboer, Shelley A Miller, A Brian Mochon, Margie A Morgan, Robin Patel, Paul C Schreckenberger, Paul D Stamper, Patricia J Simner, Nancy E Tucci, Cynthia Zimmerman, Donna M Wolk
We describe results from a multicenter study evaluating the Accelerate Pheno™ system, a first of its kind diagnostic system that rapidly identifies common bloodstream pathogens from positive blood cultures within 90 minutes and determines bacterial phenotypic antimicrobial susceptibility testing (AST) results within ∼seven h. A combination of fresh clinical and seeded blood cultures were tested and results from the Accelerate Pheno™ system were compared to VITEK® 2 for identification (ID) and broth microdilution or disk diffusion for AST...
January 5, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29304373/genomic-dna-methylation-signatures-enable-concurrent-diagnosis-and-clinical-genetic-variant-classification-in-neurodevelopmental-syndromes
#13
Erfan Aref-Eshghi, David I Rodenhiser, Laila C Schenkel, Hanxin Lin, Cindy Skinner, Peter Ainsworth, Guillaume Paré, Rebecca L Hood, Dennis E Bulman, Kristin D Kernohan, Kym M Boycott, Philippe M Campeau, Charles Schwartz, Bekim Sadikovic
Pediatric developmental syndromes present with systemic, complex, and often overlapping clinical features that are not infrequently a consequence of Mendelian inheritance of mutations in genes involved in DNA methylation, establishment of histone modifications, and chromatin remodeling (the "epigenetic machinery"). The mechanistic cross-talk between histone modification and DNA methylation suggests that these syndromes might be expected to display specific DNA methylation signatures that are a reflection of those primary errors associated with chromatin dysregulation...
January 4, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29303355/nitroimidazoles-as-hypoxic-cell-radiosensitizers-and-hypoxia-probes-misonidazole-myths-and-mistakes
#14
Peter Wardman
Nitroimidazoles have been extensively explored as hypoxic cell radiosensitizers but have had limited clinical success, with efficacy restricted by toxicity. However, they have proven clinically useful as probes for tumour hypoxia. Both applications, and probably much of the dose-limiting toxicities, reflect the dominant chemical property of electron affinity or ease of reduction, associated with the nitro substituent in an aromatic structure. This single dominant property affords unusual, indeed extraordinary flexibility in drug or probe design, suggesting further development is possible in spite of earlier limitations, in particular building on the benefit of hindsight and an appreciation of errors made in earlier studies...
January 5, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29302880/a-framework-for-tracking-former-patients-in-the-electronic-health-record-using-an-educational-registry
#15
Gregory E Brisson, Cynthia Barnard, Patrick D Tyler, David M Liebovitz, Kathy Johnson Neely
One challenge of contemporary medical education is that shorter lengths of stay and time-limited clerkships often interrupt a student's relationship with a patient before a diagnosis is made or treatment is completed, limiting the learning experience. Medical students sometimes use electronic health records (EHRs) to overcome these limitations. EHRs provide access to patients' future medical records, enabling students to track former patients across care venues to audit their diagnostic impressions and observe outcomes...
January 4, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29301584/correction-to-diagnostic-performance-of-semi-quantitative-and-quantitative-stress-cmr-perfusion-analysis-a-meta-analysis
#16
(no author information available yet)
In the original publication of this article there was an error in Figures 8, 9, 10 and 11. During typesetting the Figures 8, 9, 10 and 11 have been incorrectly swapped. In this "publisher correction" the correct and the incorrect figures are published. The original publication has been updated. BioMed central apologizes to the authors and readers for any inconvenience caused.
January 4, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29299812/capsule-commentary-on-nishizaki-et-al-awareness-of-diagnostic-error-among-japanese-residents-a-nationwide-study
#17
Akira Kuriyama
No abstract text is available yet for this article.
January 3, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29299680/validation-study-of-the-early-onset-schizophrenia-diagnosis-in-the-danish-psychiatric-central-research-register
#18
Ditte Lammers Vernal, Anne Dorte Stenstrøm, Nina Staal, Anne Marie Raabjerg Christensen, Christine Ebbesen, Anne Katrine Pagsberg, Christoph U Correll, René Ernst Nielsen, Marlene Briciet Lauritsen
The objective of this study is to assess (1) the concordance and validity of schizophrenia register diagnoses among children and adolescents (early onset schizophrenia = EOS) in the Danish Psychiatric Central Research Register (DPCRR), and (2) the validity of clinical record schizophrenia diagnoses. Psychiatric records from 200 patients with a first-time diagnosis of schizophrenia (F20.x) at age < 18 years between 1994 and 2009 in the DPCRR were rated by experienced clinicians according to ICD-10 criteria, using a predefined checklist...
January 3, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29298341/3d-reconstruction-of-coronary-arteries-from-2d-angiographic-projections-using-non-uniform-rational-basis-splines-nurbs-for-accurate-modelling-of-coronary-stenoses
#19
Francesca Galassi, Mohammad Alkhalil, Regent Lee, Philip Martindale, Rajesh K Kharbanda, Keith M Channon, Vicente Grau, Robin P Choudhury
OBJECTIVE: Assessment of coronary stenosis severity is crucial in clinical practice. This study proposes a novel method to generate 3D models of stenotic coronary arteries, directly from 2D coronary images, and suitable for immediate assessment of the stenosis severity. METHODS: From multiple 2D X-ray coronary arteriogram projections, 2D vessels were extracted. A 3D centreline was reconstructed as intersection of surfaces from corresponding branches. Next, 3D luminal contours were generated in a two-step process: first, a Non-Uniform Rational B-Spline (NURBS) circular contour was designed and, second, its control points were adjusted to interpolate computed 3D boundary points...
2018: PloS One
https://www.readbyqxmd.com/read/29297860/italian-external-quality-assessment-program-for-cystic-fibrosis-sweat-chloride-test-a-2015-and-2016-results-comparison
#20
Marco Salvatore, Giovanna Floridia, Annalisa Amato, Federica Censi, Maria Chiara de Stefano, Gianluca Ferrari, Fabrizio Tosto, Domenica Taruscio
BACKGROUND: Diagnostic testing in cystic fibrosis (CF) is based on the sweat chloride test (SCT) in the context of appropriate signs and symptoms of disease and results of the gene mutation analysis. In 2014 the Istituto Superiore di Sanità (ISS) established a pilot Italian external quality assessment program for CF sweat chloride test (Italian EQA-SCT). In 2015 this activity was recognized as a third party service carried out by the ISS. The aim of the paper is to compare 2015 and 2016 results and experiences...
October 2017: Annali Dell'Istituto Superiore di Sanità
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