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Comparative outcomes

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https://www.readbyqxmd.com/read/29166760/clinical-characteristics-and-treatment-propensity-in-elderly-patients-aged-over-80-years-with-colorectal-cancer
#1
Yun Hwa Jung, Jae Young Kim, Yu Na Jang, Sang Hoon Yoo, Gyo Hui Kim, Kang Min Lee, In Kyu Lee, Su Mi Chung, In Sook Woo
Background/Aims: Elderly patients (≥ 80 years) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ≥ 80 years with CRC in clinical practice and the impact of anticancer treatment on overall survival (OS). Methods: Medical charts of 152 elderly patients (aged ≥ 80 years) diagnosed with CRC between 1998 and 2012 were retrospectively reviewed...
November 24, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29166719/-clinical-characteristics-and-outcome-comparison-between-atrial-fibrillation-patients-underwent-catheter-ablation-under-general-aesthesia-or-local-anesthesia-and-sedation
#2
J J Xu, L J Gao, D Chang, X J Xiao, R F Zhang, J Lin, Z M Zhao, H Zhang, Y L Xia, X M Yin, Y Z Yang
Objective: To compare the outcome of radiofrequency catheter ablation under local anesthesia/sedation (S) or general anesthesia(GA) in atrial fibrillation patients. Methods: Data of 498 patients with atrial fibrillation undergoing radiofrequency catheter ablation in our departmentfrom January 2014 to December 2015 were retrospectively analyzed. Two hundred and twenty patients assigned to the GA group, the other 278 patients to the S group. Patients were followed clinically every 3 months within one year after procedure...
November 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29166703/in-hospital-outcomes-in-invasively-managed-acute-myocardial-infarction-patients-who-receive-morphine
#3
Cian P McCarthy, Vijeta Bhambhani, Eugene Pomerantsev, Jason H Wasfy
OBJECTIVE: We aimed to analyze the association between morphine and in-hospital outcomes in invasively managed ST elevation myocardial infarction (STEMI) and non-ST elevation acute coronary syndrome (NSTE-ACS) patients. BACKGROUND: Morphine is commonly used for analgesia in the setting of acute coronary syndromes (ACS); however, recently its utility in ACS has come under closer scrutiny. METHODS: We identified all STEMI and NSTE-ACS patients undergoing coronary angiogram +/- percutaneous intervention between January 2009 and July 2016 in our center and recorded patient characteristics and inpatient outcomes...
November 22, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29166702/impact-of-active-cancer-disease-on-the-outcome-of-patients-undergoing-transcatheter-aortic-valve-replacement
#4
Norman Mangner, Felix J Woitek, Stephan Haussig, David Holzhey, Georg Stachel, Florian Schlotter, Robert Höllriegel, Friedrich W Mohr, Gerhard Schuler, Axel Linke
BACKGROUND: Patients undergoing transcatheter aortic valve replacement (TAVR) are often characterized by risk factors not reflected in conventional risk scores. In this context, little is known about the outcome of patients suffering from an active cancer disease (ACD). The objective was to determine the prevalence, clinical characteristics, perioperative outcomes, and mortality of patients with ACD undergoing TAVR compared to those with a history of cancer (HCD) and controls without known tumor disease...
November 22, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29166699/comparison-of-clinical-outcomes-of-coronary-artery-stent-implantation-in-patients-with-end-stage-chronic-kidney-disease-including-hemodialysis-for-three-everolimus-eluting-ees-stent-designs-bioresorbable-polymer-ees-platinum-chromium-ees-and-cobalt-chrome-ees
#5
Takao Sato, Katsuharu Hatada, Syohei Kishi, Koichi Fuse, Satoshi Fujita, Yoshio Ikeda, Minoru Takahashi, Taku Matsubara, Masaaki Okabe, Yoshifusa Aizawa
BACKGROUNDS: New-generation bioresorbable polymer-everolimus eluting stents (BP-EES) are available. This study aimed to compare the clinical outcomes for BP-EES compared to more established stent designs, namely the platinum chromium-EES (PtCr-EES) and cobalt chrome-EES(CoCr-EES) in patients with the end-stage chronic kidney disease (CKD) including hemodialysis (HD). METHODS: One-hundred-forty-one consecutive stents (BP-EES [n = 44], PtCr-EES [n = 45], and CoCr-EES [n = 52]) were implanted in 104 patients with CKD...
November 22, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29166685/-evaluation-of-inpatient-conservative-management-of-acute-subacute-and-chronic-back-pain
#6
Ingo Haase, Kilian Haase, Bernd Kladny
Background Backache is very common in the German population. It is a common reason for people to seek medical advice and specific back pain programs have been developed. The intention of this study is to evaluate the short and long term effects of conservative management of back pain in a German general hospital. Outcomes of interest were pain intensity, interference in daily functions, physical functioning and health related quality of life. Patients and Methods We examined 1010 patients with acute, subacute and chronic back pain, admitted to inpatient nonsurgical interventional therapy in a German hospital between July 2013 and July 2015...
November 22, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29166652/do-patients-faces-influence-general-practitioners-cancer-suspicions-a-test-of-automatic-processing-of-sociodemographic-information
#7
Rosalind Adam, Roberta Garau, Edwin Amalraj Raja, Benedict Jones, Marie Johnston, Peter Murchie
BACKGROUND: Delayed cancer diagnosis leads to poorer patient outcomes. During short consultations, General Practitioners (GPs) make quick decisions about likelihood of cancer. Patients' facial cues are processed rapidly and may influence diagnosis. AIM: To investigate whether patients' facial characteristics influence immediate perception of cancer risk by GPs. DESIGN AND SETTING: Web-based binary forced choice experiment with GPs from Northeast Scotland...
2017: PloS One
https://www.readbyqxmd.com/read/29166562/a-lc-hrms-data-processing-strategy-for-reliable-sample-comparison-exemplified-by-the-assessment-of-water-treatment-processes
#8
Tobias Johannes Bader, Wolfgang Schulz, Klaus Kümmerer, Rudi Winzenbacher
The behavior of micropollutants in water treatment is an important aspect in terms of water quality. Non-target screening by liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) offers the opportunity to comprehensively assess water treatment processes by comparing the signal heights of all detectable compounds before and after treatment. Without preselection of known target compounds, all accessible information is used to describe changes across processes and thus serves as a measure for the treatment efficiency...
November 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29166543/transcatheter-or-surgical-aortic-valve-replacement-in-patients-with-advanced-kidney-disease-a-propensity-score-matched-analysis
#9
Rajkumar Doshi, Jay Shah, Vaibhav Patel, Varun Jauhar, Perwaiz Meraj
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is an alternative for surgically inoperable patients with severe aortic stenosis. Advanced kidney disease may significantly affect outcomes in patients treated with TAVR and surgical aortic valve replacement (SAVR). HYPOTHESIS: TAVR is associated with better in-hospital outcomes compared with SAVR in patients with advanced kidney disease. METHODS: We identified our sample from the National Inpatient Sample between 2012 and 2014, using International Classification of Diseases, Ninth Revision, Clinical Modification codes...
November 22, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29166408/estimating-the-impact-of-tuberculosis-anatomical-classification-on-treatment-outcomes-a-patient-and-surveillance-perspective-analysis
#10
Otavio T Ranzani, Laura C Rodrigues, Eliseu A Waldman, Carlos R R Carvalho
INTRODUCTION: Tuberculosis anatomical classification is inconsistent in the literature, which limits current tuberculosis knowledge and control. We aimed to evaluate whether tuberculosis classification impacts on treatment outcomes at patient and aggregate level. METHODS: We analyzed adults from São Paulo State, Brazil with newly diagnosed tuberculosis from 2010-2013. We used an extended clinical classification of tuberculosis, categorizing cases as pulmonary, pulmonary and extrapulmonary, extrapulmonary and miliary/disseminated...
2017: PloS One
https://www.readbyqxmd.com/read/29166407/executive-function-assessment-in-new-zealand-2-year-olds-born-at-risk-of-neonatal-hypoglycemia
#11
Judith M Ansell, Trecia A Wouldes, Jane E Harding
A growing number of babies are born with perinatal risk factors that may impair later development. These children are often assessed at 2 years to help predict outcome and direct support services. Executive function is an important predictor of academic achievement and behavior, but there are limited assessments of executive function in 2-year-olds and few have been tested in at-risk populations. Therefore, we developed a battery of four age-appropriate tasks to assess executive function in 2-year-olds. At 24 months' corrected age 368 children completed tasks assessing attention, inhibition, working memory and cognitive flexibility...
2017: PloS One
https://www.readbyqxmd.com/read/29166400/chronic-post-traumatic-intramedullary-lesions-in-dogs-a-translational-model
#12
Neringa Alisauskaite, Ingo Spitzbarth, Wolfgang Baumgärtner, Peter Dziallas, Sabine Kramer, Ricarda Dening, Veronika Maria Stein, Andrea Tipold
OBJECTIVES: Post-traumatic intramedullary myelopathies and cavitations are well described lesions following spinal cord injury (SCI) in humans and have been described in histopathological evaluations in dogs. Human intramedullary myelopathies/cavitations are associated with severe initial SCI and deterioration of clinical signs. Canine intervertebral disc extrusions share similarities with SCI in humans. In this descriptive study, magnetic resonance imaging (MRI) findings in spinal cords of dogs suffering from chronic post-traumatic myelopathies, including cavitations, are elucidated...
2017: PloS One
https://www.readbyqxmd.com/read/29166393/implicit-theories-concerning-the-intelligence-of-individuals-with-down-syndrome
#13
Claire Enea-Drapeau, Michèle Carlier, Pascal Huguet
Studies over the past three decades have shown that learning difficulties are not only determined by neurological disorders, but also by motivational and/or socio-cognitive factors Among these factors, implicit theories of intelligence (also referred to as conceptions, mindsets or beliefs about intelligence) are key elements. The belief that intelligence is fixed (entity theory), as opposed to malleable (incremental theory), is generally associated with negative teaching practices and poorer student outcomes, yet beliefs about the intelligence of individuals with intellectual disabilities have not received much attention...
2017: PloS One
https://www.readbyqxmd.com/read/29166361/the-impact-of-hepatectomy-time-of-the-liver-graft-on-post-transplant-outcome-a-eurotransplant-cohort-study
#14
Ina Jochmans, Steffen Fieuws, Ineke Tieken, Undine Samuel, Jacques Pirenne
OBJECTIVE: Assessing the effect of donor hepatectomy time on outcome after transplantation. SUMMARY OF BACKGROUND DATA: When blood supply in a deceased organ donor stops, ischemic injury starts. Livers are cooled to reduce cellular metabolism and minimize ischemic injury. This cooling is slow and livers are lukewarm during hepatectomy, potentially affecting outcome. METHODS: We used the Eurotransplant Registry to investigate the relationship between donor hepatectomy time and post-transplant outcome in 12,974 recipients of deceased-donor livers (January 1, 2004, to December 31, 2013)...
November 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29166359/incisional-hernia-after-midline-versus-transverse-specimen-extraction-incision-a-randomized-trial-in-patients-undergoing-laparoscopic-colectomy
#15
Lawrence Lee, Juan Mata, Raoul A Droeser, Pepa Kaneva, Sender Liberman, Patrick Charlebois, Barry Stein, Gerald M Fried, Liane S Feldman
OBJECTIVE: To compare the incidence of incisional hernia (IH) between midline and transverse specimen extraction site in patients undergoing laparoscopic colectomy. BACKGROUND: Midline specimen extraction incision is most commonly used in laparoscopic colectomy, but has high IH risk. IH may be lower for transverse incision. METHODS: A single-center superiority trial was conducted. Eligible patients undergoing laparoscopic colectomy were randomly assigned to midline or transverse specimen extraction...
November 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29166344/two-stage-prosthetic-breast-reconstruction-a-comparison-between-prepectoral-and-partial-subpectoral-techniques
#16
Maurice Y Nahabedian, Costanza Cocilovo
BACKGROUND: Prosthetic breast reconstruction with prepectoral placement may confer clinical advantages compared with subpectoral placement. The purpose of this study was to assess and compare clinical outcomes following 2-stage reconstruction following prepectoral and partial subpectoral placement of tissue expanders and implants. METHODS: A retrospective review of 39 (prepectoral) and 50 (partial subpectoral) patients was completed. Acellular dermal matrix was used in all patients...
December 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29166338/use-of-organs-from-hepatitis-c-virus-positive-donors-for-uninfected-recipients-a-potential-cost-effective-approach-to-save-lives
#17
Patrick B Trotter, Dominic M Summers, Ines Ushiro-Lumb, Matthew Robb, J Andrew Bradley, James Powell, Christopher J E Watson, James Neuberger
BACKGROUND: Organs from hepatitis C virus (HCV) seropositive (HCVpos) individuals are seldom used for transplantation because of the risk of disease transmission. Because transmitted HCV is now amenable to effective treatment we estimated the potential impact of using HCVpos deceased donor organs for transplantation. METHODS: The Potential Donor Audit (PDA) of patients (<80years) dying in UK critical care units and the UK Transplant Registry (UKTR) was searched to identify HCVpos potential and proceeding deceased donors...
November 22, 2017: Transplantation
https://www.readbyqxmd.com/read/29166336/valganciclovir-prophylaxis-versus-preemptive-therapy-in-cytomegalovirus-positive-renal-allograft-recipients-long-term-results-after-7-years-of-a-randomized-clinical-trial
#18
Oliver Witzke, Martin Nitschke, Michael Bartels, Heiner Wolters, Gunter Wolf, Petra Reinke, Ingeborg A Hauser, Ulrich Alshuth, Volker Kliem
BACKGROUND: The VIPP study compared valganciclovir prophylaxis with preemptive treatment regarding efficacy, safety and long-term graft outcome in CMV-positive (R+) renal transplant recipients. METHODS: Multicenter, open-label, randomized clinical study with a 12-month study phase and a follow-up of up to 84 months. Patients in the prophylaxis group received 2x450 mg/day oral valganciclovir for 100 days adjusted to renal function. Preemptive treatment with 2x900 mg/day valganciclovir was initiated at a viral load of ≥400 CMV copies/mL (PCR) and maintained over ≥14 days, followed by secondary prophylaxis...
November 22, 2017: Transplantation
https://www.readbyqxmd.com/read/29166315/poly-implants-prosth%C3%A3-se-breast-implants-a-case-series-and-review-of-the-literature
#19
Doron Klein, Eran Hadad, Itay Wiser, Omer Wolf, Ortal Itzhaki Shapira, Shir Fucks, Lior Heller
BACKGROUND: Silicone breast implants from the French manufacturer Poly Implants Prosthèse (PIP) were recalled from the European market after the French regulator has revealed the implants contain non-medical-grade silicone filler. In December 2011, following a large increase in reported rupture rate and a possible cancer risk, the French Ministry of Health recommended consideration of the PIP explantation, regardless of their condition. In 2012, the Israel Ministry of Health recommended to replace the implants only upon suspected implant rupture...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29166308/an-evaluation-of-the-choice-for-contralateral-prophylactic-mastectomy-and-patient-concerns-about-recurrence-in-a-reconstructed-cohort
#20
Ian C Sando, Jessica I Billig, Shoshana W Ambani, Casey T Kraft, Kelley M Kidwell, Lin Zhong, Kevin C Chung, Adeyiza O Momoh
BACKGROUND: Rising contralateral prophylactic mastectomy rates are a subject of national concern. This study assessed (1) factors critical to patients when deciding on contralateral prophylactic mastectomy and (2) patients' quality of life related to concerns about recurrence after unilateral or bilateral breast reconstruction. METHODS: Patients with stage 0 to III breast cancer who underwent unilateral mastectomy or contralateral prophylactic mastectomy and breast reconstruction at a single institution between 2000 and 2012 were identified...
November 21, 2017: Annals of Plastic Surgery
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