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https://www.readbyqxmd.com/read/29154695/an-evaluation-of-portable-wet-bulb-globe-temperature-monitor-accuracy
#1
Earl Cooper, Andrew Grundstein, Adam Rosen, Jessica Miles, Jupil Ko, Patrick Curry
CONTEXT:   Wet bulb globe temperature (WBGT) is the gold standard for assessing environmental heat stress during physical activity. Many manufacturers of commercially available instruments fail to report WBGT accuracy. OBJECTIVE:   To determine the accuracy of several commercially available WBGT monitors compared with a standardized reference device. DESIGN:   Observational study. SETTING:   Field test. PATIENTS OR OTHER PARTICIPANTS:   Six commercially available WBGT devices...
November 20, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/29154279/biological-factors-contributing-to-the-response-to-cognitive-training-in-mild-cognitive-impairment
#2
Jessica Peter, Lena V Schumacher, Verena Landerer, Ahmed Abdulkadir, Christoph P Kaller, Jacob Lahr, Stefan Klöppel
In mild cognitive impairment (MCI), small benefits from cognitive training were observed for memory functions but there appears to be great variability in the response to treatment. Our study aimed to improve the characterization and selection of those participants who will benefit from cognitive intervention. We evaluated the predictive value of disease-specific biological factors for the outcome after cognitive training in MCI (n = 25) and also considered motivation of the participants. We compared the results of the cognitive intervention group with two independent control groups of MCI patients (local memory clinic, n = 20; ADNI cohort, n = 302)...
November 16, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29153351/choosing-wisely-an-international-and-multimorbid-perspective
#3
Edouard J Battegay, Marcus Cheetham
Some medical diagnostic and therapeutic interventions are non-beneficial or even harmful. The Choosing Wisely campaign has encouraged the generation of "top five" lists of unnecessary low-value services in different specialist areas. In the USA alone, where the campaign was launched, these lists include a total of 450 evidence-based recommendations. Medical scientific societies in further countries such as Canada, Australia, New Zealand, England, Switzerland and Germany have since initiated Choosing Wisely campaigns...
November 15, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29149735/carbamazepine-lamotrigine-levetiracetam-and-valproic-acid-in-dried-blood-spots-with-liquid-chromatography-tandem-mass-spectrometry-method-development-and-validation
#4
Camilla Linder, Anna Hansson, Sara Sadek, Lars L Gustafsson, Anton Pohanka
Monitoring of antiepileptic drugs in children with epilepsy require multiple visits at a clinic for blood collection. Dried blood spot sampling is an alternative way of collection, performed at home by self-collection and can save time and costs for patients and family members. The aim was to develop and validate an LC-MS/MS dried blood spot method for carbamazepine, lamotrigine, levetiracetam and valproic acid with the requirements of using standard equipment and material in a routine laboratory setting. Whatman-903 filter paper was utilized, and discs were punched into a 96 well plate with an automated puncher and barcode reading...
November 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29147468/use-of-dictation-as-a-tool-to-decrease-documentation-errors-in-electronic-health-records
#5
Samer Al Hadidi, Sunil Upadhaya, Rupal Shastri, Zain Alamarat
Background: Use of Electronic Health Records is increasing. Copy-and-paste function is frequently used with higher rates of documentation errors. Studies to determine the nature of such errors are needed.Objectives: Determination of the effect of implementing a dictation system for completing notes on the quality of clinical documentation. We hypothesized that implementation of the dictation system for note writing would decrease the rate of errors in the progress notes as well as decrease the rate of copying and pasting...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29143393/an-algorithm-to-detect-unexpected-increases-in-frequency-of-reports-of-adverse-events-in-eudravigilance
#6
Luis C Pinheiro, Gianmario Candore, Cosimo Zaccaria, Jim Slattery, Peter Arlett
PURPOSE: The European Medicines Agency developed an algorithm to detect unexpected increases in frequency of reports, to enhance the ability to detect adverse events that manifest as increases in frequency, in particular quality defects, medication errors, and cases of abuse or misuse. METHODS: An algorithm based on a negative binomial time-series regression model run on 6 sequential observations prior to the monitored period was developed to forecast monthly counts of reports...
November 16, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29142437/docking-based-screening-of-ficus-religiosa-phytochemicals-as-inhibitors-of-human-histamine-h2-receptor
#7
Amit Chaudhary, Birendra Singh Yadav, Swati Singh, Pramod Kumar Maurya, Alok Mishra, Shweta Srivastva, Pritish Kumar Varadwaj, Nand Kumar Singh, Ashutosh Mani
Background: Ficus religiosa L. is generally known as Peepal and belongs to family Moraceae. The tree is a source of many compounds having high medicinal value. In gastrointestinal tract, histamine H2 receptors have key role in histamine-stimulated gastric acid secretion. Their over stimulation causes its excessive production which is responsible for gastric ulcer. Objective: This study aims to screen the range of phytochemicals present in F. religiosa for binding with human histamine H2 and identify therapeutics for a gastric ulcer from the plant...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142411/the-effect-of-polyherbal-medicines-used-for-the-treatment-of-tuberculosis-on-other-opportunistic-organisms-of-humans-infected-with-tuberculosis
#8
Elizabeth Bosede Famewo, Anna Maria Clarke, Anthony Jide Afolayan
Background: In many immunocompromised patients, opportunistic bacterial and fungal infections are common. Polyherbal medicines examined in this study are used by the indigenous people of South Africa for the treatment of tuberculosis (TB) and other opportunistic infections associated with TB. Objective: To evaluate the antibacterial and antifungal activity of nine polyherbal remedies against four Gram-positive and Gram-negative bacteria respectively and three fungi...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29142398/cytotoxic-antimitotic-and-antiproliferation-studies-on-rasam-a-south-indian-traditional-functional-food
#9
Agilandeswari Devarajan, M K Mohan Maruga Raja
Background: Rasam is a traditional South Indian food, prepared using tamarind juice as a base, with a variety of spices. Rasam, with all its ingredients medicinally claimed for various ailments, is a functional food. Systematic consumption of traditional functional food provides an excellent preventive measure to ward off many diseases. Objective: To study rasam for cytotoxic, antimitotic, and antiproliferation potential beyond its culinary and nutritional effect...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141604/genome-wide-identification-of-mirnas-and-lncrnas-in-cajanus-cajan
#10
Chandran Nithin, Amal Thomas, Jolly Basak, Ranjit Prasad Bahadur
BACKGROUND: Non-coding RNAs (ncRNAs) are important players in the post transcriptional regulation of gene expression (PTGR). On one hand, microRNAs (miRNAs) are an abundant class of small ncRNAs (~22nt long) that negatively regulate gene expression at the levels of messenger RNAs stability and translation inhibition, on the other hand, long ncRNAs (lncRNAs) are a large and diverse class of transcribed non-protein coding RNA molecules (> 200nt) that play both up-regulatory as well as down-regulatory roles at the transcriptional level...
November 15, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29139057/cadaveric-simulation-a-review-of-reviews
#11
REVIEW
M Yiasemidou, E Gkaragkani, D Glassman, C S Biyani
BACKGROUND: Traditional surgical training, largely based on the Halstedian model "see one, do one, teach one" is not as effective in the era of working time restrictions and elaborate shift-patterns. As a result, contemporary surgeons turned to educational methods outside the operating theatre such as simulation. Cadavers are high fidelity models but their use has ethical and cost implications and their availability may be limited. In this review, we explore the role of cadaveric simulation in modern surgical education...
November 14, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29137959/moving-from-clinic-to-home-what-the-future-holds-for-ophthalmic-telemedicine
#12
Nancy M Holekamp
PURPOSE: To describe the expanding role of telemedicine in healthcare, the key criteria required for a successful device and program implementation, and the current and future role of home monitoring in ophthalmology. DESIGN: Expert perspective METHODS: Analysis with real-world interpretation of home monitoring technologies including current adoption barriers and expanded future demands based on demographic and market forces. RESULTS: Remote patient monitoring represents a paradigm shift in the way physicians care for patients...
November 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29134673/modified-dixon-based-renal-dynamic-contrast-enhanced-mri-facilitates-automated-registration-and-perfusion-analysis
#13
Anneloes de Boer, Tim Leiner, Eva E Vink, Peter J Blankestijn, Cornelis A T van den Berg
PURPOSE: Renal dynamic contrast-enhanced (DCE) MRI provides information on renal perfusion and filtration. However, clinical implementation is hampered by challenges in postprocessing as a result of misalignment of the kidneys due to respiration. We propose to perform automated image registration using the fat-only images derived from a modified Dixon reconstruction of a dual-echo acquisition because these provide consistent contrast over the dynamic series. METHODS: DCE data of 10 hypertensive patients was used...
November 13, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29134292/simultaneous-determination-of-brazilin-and-protosappanin-b-in-caesalpinia-sappan-by-ionic-liquid-dispersive-liquid-phase-microextraction-method-combined-with-hplc
#14
Zhaoyang Xia, Dongdong Li, Qing Li, Yan Zhang, Wenyi Kang
The conditions of heating, ionic liquid-based ultrasonic-assisted extraction combined with reverse-phase high performance liquid chromatography were optimized to simultaneously isolate and determinate brazilin and protosappanin B in Caesalpinia sappan. Ionic liquids, including [BMIM]Br, [BMIM]BF4, [BMIM]PF6 and [HMIM]PF6, were selected as extraction solvents while methanol, acetone, acetonitrile, ethanol and water were selected as dispersants. The chromatographic column was Purospher star RP-C18 (250 mm × 4...
November 13, 2017: Chemistry Central Journal
https://www.readbyqxmd.com/read/29134189/toward-uniform-implementation-of-parametric-map-digital-imaging-and-communication-in-medicine-standard-in-multisite-quantitative-diffusion-imaging-studies
#15
Dariya Malyarenko, Andriy Fedorov, Laura Bell, Melissa Prah, Stefanie Hectors, Lori Arlinghaus, Mark Muzi, Meiyappan Solaiyappan, Michael Jacobs, Maggie Fung, Amita Shukla-Dave, Kevin McManus, Michael Boss, Bachir Taouli, Thomas E Yankeelov, Christopher Chad Quarles, Kathleen Schmainda, Thomas L Chenevert, David C Newitt
This paper reports on results of a multisite collaborative project launched by the MRI subgroup of Quantitative Imaging Network to assess current capability and provide future guidelines for generating a standard parametric diffusion map Digital Imaging and Communication in Medicine (DICOM) in clinical trials that utilize quantitative diffusion-weighted imaging (DWI). Participating sites used a multivendor DWI DICOM dataset of a single phantom to generate parametric maps (PMs) of the apparent diffusion coefficient (ADC) based on two models...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29133491/exploring-attributes-of-high-value-primary-care
#16
Melora Simon, Niteesh K Choudhry, Jim Frankfort, David Margolius, Julia Murphy, Luis Paita, Thomas Wang, Arnold Milstein
PURPOSE: Medicare's merit-based incentive payment system and narrowing of physician networks by health insurers will stoke clinicians' and policy makers' interest in care delivery attributes associated with value as defined by payers. METHODS: To help define these attributes, we analyzed 2009 to 2011 commercial health insurance claims data for more than 40 million preferred provider organization patients attributed to over 53,000 primary care practice sites. We identified sites ranking favorably on both quality and low total annual per capita health care spending ("high-value") and sites ranking near the median ("average-value")...
November 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/29132914/comparison-of-cyclopentolate-versus-tropicamide-cycloplegia-a-systematic-review-and-meta-analysis
#17
Negareh Yazdani, Ramin Sadeghi, Hamed Momeni-Moghaddam, Leili Zarifmahmoudi, Asieh Ehsaei
PURPOSE: The aim of the present meta-analysis is to compare the efficacy of cyclopentolate and tropicamide in controlling accommodation during refraction. METHODS: A comprehensive literature search was performed in PubMed, Scopus, Science direct and Ovid databases by the key words: "tropicamide"; "cyclopentolate"; "cycloplegia" and "cycloplegic" from inception to April 2016. Methodological quality of the literature was evaluated according to the Oxford Center for Evidence Based Medicine and modified Newcastle-Ottawa scale...
November 10, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/29132624/the-value-of-ehr-based-assessment-of-physician-competency-an-investigative-effort-with-internal-medicine-physicians
#18
Kimberly Venta, Erin Baker, Cali Fidopiastis, Kay Stanney
OBJECTIVE: The purpose of this study was to investigate the potential of developing an EHR-based model of physician competency, named the Skill Deficiency Evaluation Toolkit for Eliminating Competency-loss Trends (Skill-DETECT), which presents the opportunity to use EHR-based models to inform selection of Continued Medical Education (CME) opportunities specifically targeted at maintaining proficiency. METHODS: The IBM Explorys platform provided outpatient Electronic Health Records (EHRs) representing 76 physicians with over 5000 patients combined...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29131618/np-structurepredictor-prediction-of-unknown-natural-products-in-plant-mixtures
#19
Yeu-Chern Harn, Bo-Han Su, Yuan-Ling Ku, Olivia A Lin, Cheng-Fu Chou, Yufeng Jane Tseng
Identification of the individual chemical constituents of a mixture, especially solutions extracted from medicinal plants, is a time-consuming task. The identification results are often limited by challenges such as the development of separation methods and the availability of known reference standards. A novel structure elucidation system, NP-StructurePredictor, is presented and used to accelerate the process of identifying chemical structures in a mixture based on a branch and bound algorithm combined with a large collection of natural product databases...
November 13, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29130519/velocity-reconstruction-with-nonconvex-optimization-for-low-velocity-encoding-phase-contrast-mri
#20
Michael Loecher, Daniel B Ennis
PURPOSE: To introduce and demonstrate a nonconvex optimization method for reconstructing velocity data from low-velocity-encoding (Venc ) phase-contrast MRI data. THEORY AND METHODS: Solving for velocity values from phase-contrast MRI data was formulated as a nonconvex optimization problem. Weighting was added to account for intravoxel dephasing, and a Laplacian-based regularization was used to account for residual velocity aliasing. The reconstruction was tested with two low-Venc schemes: dual-Venc and a multidirectional high-moment encoding...
November 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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