Read by QxMD icon Read

stress cmr

Apostolos Kiaos, Ioannis Tziatzios, Stavros Hadjimiltiades, Charalambos Karvounis, Theodoros D Karamitsos
Stress perfusion cardiac magnetic resonance (CMR) has been proposed as an important gatekeeper for invasive coronary angiography (ICA) and percutaneous coronary interventions (PCI) in patients evaluated for possible coronary artery disease (CAD) (Fihn et al., 2012; Montalescot et al., 2013) [1], [2]. Several meta-analyses have evaluated the accuracy of stress perfusion CMR to diagnose CAD at the vessel level (Danad et al., 2017; Dai et al., 2016; Jiang et al., 2016; Takx et al., 2015; Li et al., 2015; Desai and Jha, 2013; Jaarsma et al...
February 2018: Data in Brief
Ali J Marian, Yanli Tan, Lili Li, Jeffrey T Chang, Petros Syrris, Manouchehr Hessabi, Mohammad H Rahbar, James T Willerson, Benjamin Y Cheong, Chia-Ying Liu, Neal S Kleiman, David A Bluemke, Sherif F Nagueh
<u>Rationale:</u> Hypertrophic cardiomyopathy (HCM) is a genetic paradigm of cardiac hypertrophy. Cardiac hypertrophy and interstitial fibrosis are important risk factors for sudden death and morbidity in HCM. Oxidative stress is implicated in the pathogenesis of cardiac hypertrophy and fibrosis. Treatment with anti-oxidant N-acetylcysteine (NAC) reverses cardiac hypertrophy and fibrosis in animal models of HCM. <u>Objective:</u> To determine effect sizes of NAC on indices of cardiac hypertrophy and fibrosis in patients with established HCM...
March 14, 2018: Circulation Research
Allison D Ta, Li-Yueh Hsu, Hannah M Conn, Susanne Winkler, Anders M Greve, Sujata M Shanbhag, Marcus Y Chen, W Patricia Bandettini, Andrew E Arai
BACKGROUND: Dark rim artifacts in first-pass cardiovascular magnetic resonance (CMR) perfusion images can mimic perfusion defects and affect diagnostic accuracy for coronary artery disease (CAD). We evaluated whether quantitative myocardial blood flow (MBF) can differentiate dark rim artifacts from true perfusion defects in CMR perfusion. METHODS: Regadenoson perfusion CMR was performed at 1.5 T in 76 patients. Significant CAD was defined by quantitative invasive coronary angiography (QCA) ≥ 50% diameter stenosis...
March 8, 2018: Journal of Cardiovascular Magnetic Resonance
Lukas Stoiber, Bernhard Schnackenburg, Rolf Gebker, Hanane Hireche-Chikaoui, Burkert Pieske, Sebastian Kelle
BACKGROUND: Severe obesity is asscociated with an increased risk of coronary artery disease (CAD) but non-invasive cardiac imaging modalities have important technical limits. CASE PRESENTATION: We report a case of a 58-year old patient with suspected CAD and severely elevated BMI of 58 kg/m2 . CONCLUSIONS: Stress-CMR was able to non-invasively stratify risk with good imaging quality despite the body dimensions of the patient.
March 5, 2018: BMC Cardiovascular Disorders
Sahadev T Reddy, Ngoc L Thai, Jose Oliva, Kusum B Tom, Michael K Dishart, Mark Doyle, June A Yamrozik, Ronald B Williams, Moneal Shah, Adil Wani, Anil Singh, Rishi Maheswary, Robert W W Biederman
BACKGROUND: The preoperative workup of orthotopic liver transplantation (OLT) patents is practically complex given the need for multiple imaging modalities. We recently demonstrated in our Proof-of-Concept study the value of a One-Stop-Shop approach using Cardiovascular MRI (CMR) to address this complex problem. However, this approach requires further validation in a larger cohort, as detection of HCC as well as cardiovascular risk assessment is critically important in these patients...
March 2, 2018: Clinical Transplantation
Kenneth Mangion, Kirsty McDowell, Patrick B Mark, Elaine Rutherford
Purpose of Review: The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD). We conducted a literature review in line with current guidelines. Recent Findings: The authors identified 22 studies. Patients with CKD had left ventricular global and regional dysfunction and adverse remodeling. Stress testing with CMR revealed a reduced stress-response in CKD patients...
2018: Current Cardiovascular Imaging Reports
Alexander Liu, Rohan S Wijesurendra, Joanna M Liu, John C Forfar, Keith M Channon, Michael Jerosch-Herold, Stefan K Piechnik, Stefan Neubauer, Rajesh K Kharbanda, Vanessa M Ferreira
BACKGROUND: In patients with angina and nonobstructive coronary artery disease (NOCAD), confirming symptoms due to coronary microvascular dysfunction (CMD) remains challenging. Cardiac magnetic resonance (CMR) assesses myocardial perfusion with high spatial resolution and is widely used for diagnosing obstructive coronary artery disease (CAD). OBJECTIVES: The goal of this study was to validate CMR for diagnosing microvascular angina in patients with NOCAD, compared with patients with obstructive CAD and correlated to the index of microcirculatory resistance (IMR) during invasive coronary angiography...
March 6, 2018: Journal of the American College of Cardiology
Alexander Liu, Rohan S Wijesurendra, Joanna M Liu, Andreas Greiser, Michael Jerosch-Herold, John C Forfar, Keith M Channon, Stefan K Piechnik, Stefan Neubauer, Rajesh K Kharbanda, Vanessa M Ferreira
BACKGROUND: Novel cardiac magnetic resonance (CMR) stress T1 mapping can detect ischemia and myocardial blood volume changes without contrast agents and may be a more comprehensive ischemia biomarker than myocardial blood flow. OBJECTIVES: This study describes the performance of the first prospective validation of stress T1 mapping against invasive coronary measurements for detecting obstructive epicardial coronary artery disease (CAD), defined by fractional flow reserve (FFR <0...
March 6, 2018: Journal of the American College of Cardiology
L Bière, G Garcia, S Guillou, F Larcher, A Furber, S Willoteaux, D Mirebeau-Prunier, F Prunier
Out of 163 STEMI patients, 33 presented left ventricular remodeling (LVR) as assessed by multiple cardiac magnetic resonance (CMR) scans. LVR patients were identified as EarlyLVR (LVR occurring between baseline and 3 months) or LateLVR (LVR occurring between 3 months and one year), and matched to non-remodeler patients in term of age, gender, anterior infarction, baseline LV ejection fraction and infarct size. ST2 and NT-proBNP were measured at baseline and 3 months. Systolic wall stress (SWS) was calculated by CMR...
February 19, 2018: International Journal of Cardiology
Benjamin Zorach, Peter W Shaw, Jamieson Bourque, Sujith Kuruvilla, Pelbreton C Balfour, Yang Yang, Roshin Mathew, Jonathan Pan, Jorge A Gonzalez, Angela M Taylor, Craig H Meyer, Frederick H Epstein, Christopher M Kramer, Michael Salerno
BACKGROUND: Preliminary semi-quantitative cardiovascular magnetic resonance (CMR) perfusion studies have demonstrated reduced myocardial perfusion reserve (MPR) in patients with angina and risk factors for microvascular disease (MVD), however fully quantitative CMR has not been studied. The purpose of this study is to evaluate whether fully quantitative CMR identifies reduced MPR in this population, and to investigate the relationship between epicardial atherosclerosis, left ventricular hypertrophy (LVH), extracellular volume (ECV), and perfusion...
February 22, 2018: Journal of Cardiovascular Magnetic Resonance
Li-Yueh Hsu, Matthew Jacobs, Mitchel Benovoy, Allison D Ta, Hannah M Conn, Susanne Winkler, Anders M Greve, Marcus Y Chen, Sujata M Shanbhag, W Patricia Bandettini, Andrew E Arai
OBJECTIVES: The authors developed a fully automated framework to quantify myocardial blood flow (MBF) from contrast-enhanced cardiac magnetic resonance (CMR) perfusion imaging and evaluated its diagnostic performance in patients. BACKGROUND: Fully quantitative CMR perfusion pixel maps were previously validated with microsphere MBF measurements and showed potential in clinical applications, but the methods required laborious manual processes and were excessively time-consuming...
February 9, 2018: JACC. Cardiovascular Imaging
Magalie Ladouceur, Stephanie Baron, Valérie Nivet-Antoine, Gérard Maruani, Gilles Soulat, Helena Pereira, Anne Blanchard, Pierre Boutouyrie, Jean Louis Paul, Elie Mousseaux
BACKGROUND: Heart failure is a serious event in patients with transposition of the great arteries (D-TGA) after atrial redirection surgery. We aimed to determine the association between myocardial fibrosis and systolic and diastolic systemic right ventricle (sRV) dysfunction. METHODS: Diastolic and systolic function of sRV was prospectively assessed using echocardiography and cardiac magnetic resonance imaging (CMR) in 48 patients with atrially switched D-TGA and 26 healthy subjects...
January 31, 2018: International Journal of Cardiology
Shiro Nakamori, Hajime Sakuma, Kaoru Dohi, Masaki Ishida, Takashi Tanigawa, Akimasa Yamada, Shinichi Takase, Hiroshi Nakajima, Toshiki Sawai, Jun Masuda, Motonori Nagata, Yasutaka Ichikawa, Kakuya Kitagawa, Eitaro Fujii, Norikazu Yamada, Masaaki Ito
BACKGROUND: Recent studies using stress-rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR). However, its diagnostic concordance may be reduced in patients with multivessel disease. We sought to evaluate the concordance of adenosine stress-rest perfusion CMR for predicting reduced FFR, and to determine the additive value of measuring global coronary flow reserve (CFR) in the coronary sinus in multivessel disease...
January 26, 2018: Journal of the American Heart Association
Ruixi Zhou, Wei Huang, Yang Yang, Xiao Chen, Daniel S Weller, Christopher M Kramer, Sebastian Kozerke, Michael Salerno
BACKGROUND: Cardiovascular magnetic resonance (CMR) stress perfusion imaging provides important diagnostic and prognostic information in coronary artery disease (CAD). Current clinical sequences have limited temporal and/or spatial resolution, and incomplete heart coverage. Techniques such as k-t principal component analysis (PCA) or k-t sparcity and low rank structure (SLR), which rely on the high degree of spatiotemporal correlation in first-pass perfusion data, can significantly accelerate image acquisition mitigating these problems...
February 1, 2018: Journal of Cardiovascular Magnetic Resonance
Tom Gyllenhammar, Mikael Kanski, Henrik Engblom, Dirk M Wuttge, Marcus Carlsson, Roger Hesselstrand, Håkan Arheden
BACKGROUND: Patients with systemic sclerosis (SSc) have high cardiovascular mortality even though there is no or little increase in prevalence of epicardial coronary stenosis. First-pass perfusion on cardiovascular magnetic resonance (CMR) have detected perfusion defects indicative of microvascular disease, but the quantitative extent of hypoperfusion is not known. Therefore, we aimed to determine if patients with SSc have lower global myocardial perfusion (MP) at rest or during adenosine stress, compared to healthy controls, quantified with CMR...
January 30, 2018: BMC Cardiovascular Disorders
Karthigesh Sree Raman, Gaetano Nucifora, Joseph B Selvanayagam
Cardiovascular Magnetic Resonance Imaging (CMR) permits accurate phenotyping of many cardiac diseases. CMR's inherent advantages are its non-invasive nature, lack of ionizing radiation and high accuracy and reproducibility. Furthermore, it is able to assess many aspects of cardiac anatomy, structure and function. Specifically, it can characterize myocardial tissue, myocardial function, myocardial mass, myocardial blood flow/perfusion, irreversible and reversible injury, all with a high degree of accuracy and reproducibility...
January 19, 2018: Clinical and Experimental Pharmacology & Physiology
Rene Nkoulou, Mathias Wolfrum, Aju P Pazhenkottil, Michael Fiechter, Ronny R Buechel, Oliver Gaemperli, Philipp A Kaufmann
BACKGROUND: Left ventricular (LV) ejection fraction (EF) during high dobutamine stress (HD) by real-time gated-SPECT myocardial perfusion imaging (MPI) on a cadmium-zinc-telluride (CZT) gamma camera was validated versus cardiac magnetic resonance imaging (CMR). METHODS AND RESULTS: After injecting 99mTc-tetrofosmin (320 MBq) in 50 patients (mean age 64 +/- 11 years), EF at rest and post-stress as well as relevant changes in EF at HD (ΔEF ≥ 5%) were assessed. CZT and CMR rest EF values yielded an excellent correlation and agreement (r = 0...
January 16, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Prathap Kanagala, Adrian S H Cheng, Anvesha Singh, John McAdam, Anna-Marie Marsh, Jayanth R Arnold, Iain B Squire, Leong L Ng, Gerry P McCann
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a poorly characterized condition. We aimed to phenotype patients with HFpEF using multiparametric stress cardiovascular magnetic resonance imaging (CMR) and to assess the relationship to clinical outcomes. METHODS: One hundred and fifty four patients (51% male, mean age 72 ± 10 years) with a diagnosis of HFpEF underwent transthoracic echocardiography and CMR during a single study visit. The CMR protocol comprised cine, stress/rest perfusion and late gadolinium enhancement imaging on a 3T scanner...
January 11, 2018: Journal of Cardiovascular Magnetic Resonance
Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Mi Young Kim, Je Kyoun Shin, Sung Min Ko
Background Non-invasive anatomical and physiological evaluations of coronary artery disease (CAD) may be obtained with static single-scan stress perfusion cardiac computed tomography (SSPCT). Purpose To determine the diagnostic performance of static SSPCT for identifying hemodynamically significant CAD. Material and Methods This prospective study included 29 patients with suspected or known CAD who underwent static SSPCT, cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI), and invasive coronary angiography (ICA)...
January 1, 2018: Acta Radiologica
P Garg, R Aziz, T Al Musa, D P Ripley, P Haaf, J R J Foley, P P Swoboda, G J Fent, L E Dobson, J P Greenwood, S Plein
AIMS: Myocardial perfusion imaging during hyperaemic stress is commonly used to detect coronary artery disease. The aim of this study was to investigate the relationship between left ventricular global longitudinal strain (GLS), strain rate (GLSR), myocardial early (E') and late diastolic velocities (A') with adenosine stress first-pass perfusion cardiovascular magnetic resonance (CMR) imaging. METHODS AND RESULTS: 44 patients met the inclusion criteria and underwent CMR imaging...
January 8, 2018: Netherlands Heart Journal
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"