keyword
MENU ▼
Read by QxMD icon Read
search

Lipid emulsion

keyword
https://www.readbyqxmd.com/read/28634377/hepatoprotective-and-in-vitro-antioxidant-effects-of-native-depolymerised-exopolysaccharides-derived-from-termitomyces-albuminosus
#1
Huajie Zhao, Juan Li, Jianjun Zhang, Xiuxiu Wang, Min Liu, Chen Zhang, Le Jia
In this study, native depolymerised-exopolysaccharides (DEPS) were successfully derived from the exopolysaccharides (EPS) of Termitomyces albuminosus, and its hepatoprotective effects against a high-fat emulsion and in vitro antioxidant activities were investigated. Based on the results of in vitro assays, DEPS showed superior antioxidant activities compared with EPS dose-dependently. According to the in vivo assays both EPS and DEPS significantly decreased the lipid levels, improved the enzymatic activities, and reduced lipid peroxidation in both serum and hepatic homogenates...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28633826/optimization-and-characterization-of-ultrasound-assisted-preparation-of-curcumin-loaded-solid-lipid-nanoparticles-application-of-central-composite-design-thermal-analysis-and-x-ray-diffraction-techniques
#2
Elham Sadati Behbahani, Mehrorang Ghaedi, Mohammadreza Abbaspour, Kobra Rostamizadeh
This study is devoted to preparation of novel solid lipid nanoparticles (SLNs) for the encapsulation of curcumin which is produced by micro-emulsion and ultrasonication using stearic acid and tripalmitin as solid lipids, tween80 and span80 as surfactants. The relation between particle size and entrapment efficiency of the produced SLNs was operated by central composite design (CCD) under response likes surface method (RSM). The variables including the ratio of lipids (X1), the ratio of surfactants (X2), drug/lipid ratio (X3), time of sonication (X4) and time of homogenization (X5)...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28633010/tensing-up-for-lipid-droplet-formation
#3
Aurélien Roux, Robbie Loewith
Lipid droplets are fat storage organelles in cells that physically resemble stable oil-water emulsion droplets. In this issue of Developmental Cell, Ben M'barek et al. (2017) show that the resemblance is more than superficial: physical principles governing emulsion stability also control lipid droplet nucleation and growth.
June 19, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28629353/lipid-emulsion-mitigates-impaired-pulmonary-function-induced-by-limb-ischemia-reperfusion-in-rats-through-attenuation-of-local-cellular-injury-and-the-subsequent-systemic-inflammatory
#4
Fangfang Xia, Yun Xia, Sisi Chen, Lulu Chen, Weijuan Zhu, Yuanqing Chen, Thomas J Papadimos, Xuzhong Xu, Le Liu
BACKGROUND: Limb ischemia/reperfusion causes inflammation and elicits oxidative stress that may lead to local tissue damage and remote organ such as lung injury. This study investigates pulmonary function after limb ischemia/reperfusion and the protective effect of a lipid emulsion (Intralipid). METHODS: Twenty-four rats were divided into three groups: sham operation group (group S), ischemia/reperfusion group (group IR), and lipid emulsion treatment group (group LE)...
June 19, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28624597/suppressive-effect-of-kamebakaurin-on-acetaminophen-induced-hepatotoxicity-by-inhibiting-lipid-peroxidation-and-inflammatory-response-in-mice
#5
Hiroki Yoshioka, Yutaka Aoyagi, Nobuyuki Fukuishi, Ming-Yu Gui, Yong-Ri Jin, Xu-Wen Li, Yoshiyuki Adachi, Naohito Ohno, Koichi Takeya, Yukio Hitotsuyanagi, Nobuhiko Miura, Tsunemasa Nonogaki
BACKGROUND: Kamebakaurin (KA) is an ent-kaurane diterpenoid known to have anti-inflammatory potential. In the current study, we investigated whether pretreatment with KA could ameliorate acetaminophen (APAP)-induced hepatotoxicity by inhibiting the anti-inflammatory response in mice. METHODS: Seven-week-old C57BL/6J mice were orally administered KA or olive oil emulsion for seven days. Twenty-four hours after the last KA or olive oil administration, the mice were intraperitoneally injected with 400mg/kg APAP or saline under feed deprived condition...
April 12, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28620913/efficacy-of-oral-lipid-based-formulations-of-apomorphine-and-its-diester-in-a-parkinson-s-disease-rat-model
#6
Nrupa Borkar, Daniel R Andersson, Mingshi Yang, Anette Müllertz, René Holm, Huiling Mu
OBJECTIVES: Apomorphine is used to symptomatically treat Parkinson's disease (PD). Oral delivery of apomorphine is generally limited by its short plasma half-life and a hepatic first-pass metabolism. This study was aimed at evaluating the behavioural response of apomorphine and its prodrug administered in oral lipid-based formulations. METHODS: The behavioural response of apomorphine and its prodrug administered in oral lipid-based formulations was evaluated using a 6-hydroxydopamine-lesioned rat model simulating PD symptomatology...
June 16, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28612562/-pancreatic-%C3%AE-cell-dysfunction-and-apoptosis-induced-by-elevated-free-fatty-acids-synergize-with-hyperglycemia
#7
Hui-Wen Tan, Nai-Qian Zhao, Ye-Rong Yu, Li-Na Han, Xiang-Xun Zhang
OBJECTIVES: To analysis the effects of glucoxicity and lipotoxicity on the function and apoptosis of pancreatic β-cells. METHODS: The levels of circulating glucose and free fat acids (FFAs) were elevated by infusion dextrose and fat emulsion in high-fat obese rats. The insulin resistance model obese rats were divided into four gourp: obese group with saline infusion (OB-NS group, n=7), obese group with glucose infusion (OB-GS group, n=9), obese group with Lipid emulsion infusion (OB-FFA group, n=8), obese group with glucose and lipid emulsion infusion (OB-FG group, n=9)...
January 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28609117/microchannel-emulsification-a-promising-technique-towards-encapsulation-of-functional-compounds
#8
Nauman Khalid, Isao Kobayashi, Marcos A Neves, Kunihiko Uemura, Mitsutoshi Nakajima
This review provides an overview of microchannel emulsification (MCE) for production of functional monodispersed emulsion droplets. The main emphasis has been put on functional bioactives encapsulation using grooved-type and straight-through microchannel array plates. MCE successfully encapsulates the bioactives like β-carotene, oleuropein, γ-oryzanol, β-sitosterol, L-ascorbic acid and ascorbic acid derivatives, vitamin D and quercetin. These bioactives were encapsulated in a variety of delivery systems like simple and multiple emulsions, polymeric particles, microgels, solid lipid particles and functional vesicles...
June 13, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28608781/nano-and-microparticles-at-fluid-and-biological-interfaces
#9
Sabyasachi Dasgupta, Thorsten Auth, Gerhard Gompper
Systems with interfaces are abundant in both technological applications and biology. While a fluid interface separates two fluids, membranes separate the inside of vesicles from the outside, the interior of biological cells from the environment, and compartmentalize cells into organelles. The physical properties of interfaces are characterized by interface tension, those of membranes are characterized by bending and stretching elasticity. Amphiphilic molecules like surfactants that are added to a system with two immiscible fluids decrease the interface tension and induce a bending rigidity...
June 13, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28606522/functionality-and-nutritional-aspects-of-microcrystalline-cellulose-in-food
#10
REVIEW
John Nsor-Atindana, Maoshen Chen, H Douglas Goff, Fang Zhong, Hafiz Rizwan Sharif, Yue Li
Microcrystalline cellulose (MCC) is among the most commonly used cellulose derivatives in the food industry. In order assess the recent advances of MCC in food product development and its associated nutraceutical implications, google scholar and database of journals subscribed by Jiangnan university, China were used to source literature. Recently published research articles that reported physicochemical properties of MCC for food application or potential application in food and nutraceutical functions were reviewed and major findings outlined...
September 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28606477/n-3-polyunsaturated-fatty-acid-enriched-lipid-emulsion-improves-paneth-cell-function-via-the-il-22-stat3-pathway-in-a-mouse-model-of-total-parenteral-nutrition
#11
Jiwei Wang, Feng Tian, Huijun Zheng, Hao Tian, Peng Wang, Li Zhang, Xuejin Gao, Xinying Wang
Total parenteral nutrition (TPN) is a life-saving therapy for patients with gastrointestinal dysfunction or failure. Long-term TPN impairs gut barrier function and contributes to infections and poor clinical outcomes. However, the underlying mechanisms of TPN-related gut barrier damage has not been fully elucidated, and effective measures are still rare. Here, we compared the effects of a predominantly n-6 polyunsaturated fatty acids emulsion (PUFAs; Intralipid) and a lipid emulsion containing n-3 PUFAs (Intralipid plus Omegaven) on antimicrobial peptides produced by Paneth cells...
June 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28598497/descriptive-and-temporal-saltiness-perception-properties-of-model-solid-lipoproteic-colloid-foods-implications-for-sodium-reduction
#12
Wan-Yuan Kuo, Youngsoo Lee
Solid lipoproteic colloid (SLC) foods that consist of an oil-in-water emulsion of lipid and protein such as cheese and sausage contribute a significant amount of sodium to modern diets. This study aimed to correlate the overall saltiness perception to the texture and temporal saltiness perception of SLCs to understand saltiness perception during oral processing. Model SLCs with varying levels of protein and fat were prepared via pressure homogenization of whey protein isolate, anhydrous milk fat, and NaCl, followed by heat-induced gelation...
June 9, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28595482/development-of-edible-films-obtained-from-submicron-emulsions-based-on-whey-protein-concentrate-oil-beeswax-and-brea-gum
#13
Juan Pablo Cecchini, María J Spotti, Andrea M Piagentini, Viviana G Milt, Carlos R Carrara
Edible films with whey protein concentrate (WPC) with a lipid component, sunflower oil (O) or beeswax (W), to enhance barrier to water vapor were obtained. Brea gum was used as emulsifier and also as matrix component. In order to achieve emulsion with small and homogeneous droplet size, an ultrasonicator equipment was used after obtaining a pre-emulsion using a blender. The films were made by casting. Effects of lipid fraction on droplet size, zeta potential, mechanical properties, water vapor permeability (WVP), solubility, and optical properties were determined...
June 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28587401/antioxidant-properties-of-the-red-alga-asparagopsis-taxiformis-collected-on-the-north-west-algerian-coast
#14
Zoheir Mellouk, Ilhem Benammar, Djamil Krouf, Makhlouf Goudjil, Meriem Okbi, Willy Malaisse
The aim of the present study was to evaluate the total phenolic and lipid content, fatty acids profiles and in vitro antioxidant activities of aqueous and solvent extracts of the red seaweed Asparagopsis taxiformis, through six different investigations. The present study demonstrated that phenol contents (mg gallic acid/g dry weight) were highest in the aqueous and methanolic extracts, followed by the ethanolic, hydroethanolic and hydromethanolic extracts. The lowest phenol contents were identified in the three remaining extracts: Butanolic, petroleum ether and acetone extracts...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28581831/development-and-characterization-of-new-and-scalable-topical-formulations-containing-n-acetyl-d-glucosamine-loaded-solid-lipid-nanoparticles
#15
Joana Marto, Cecilia Sangalli, Priscilla Capra, Paola Perugini, Andreia Ascenso, Lídia Gonçalves, Helena Ribeiro
N-Acetyl-d-glucosamine (NAG) has been recently considered for topical treatment of hyperpigmentation disorders due to its inhibitory effect on thyrosinase enzymes in melanocytes. NAG is a precursor of hyaluronic acid, increasing its amount in skin, and consequently, preserving the skin hydration and elasticity. It may also act as an emulsion stabilizer. Solid lipid nanoparticles (SLN) are advanced delivery systems successfully used in pharmaceutical and cosmetic formulations for the improvement of active molecules penetration into the skin...
June 21, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28578070/comprehensive-characterization-of-bioactive-peptides-from-buffalo-bubalus-bubalis-colostrum-and-milk-fat-globule-membrane-proteins
#16
N Brijesha, H S Aparna
Milk fat is dispersed in milk as small spherical globules stabilized in the form of emulsion by its surrounding membrane, often referred to as fat globule membrane (FGM). Buffalo, a major milking mammal of Asia and second most milking mammal across the globe presents physicochemical features different from that of other ruminant species containing higher content of lipids and proteins. The present study describes characterization of FGM proteins isolated from both buffalo milk and colostrum. A detailed proteomic analysis of peptides generated by in vitro gastrointestinal simulation digestion of buffalo milk and colostrum FGM fractions was performed by nLC-ESI MS/MS...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28576561/antimicrobial-activity-of-polymyxin-loaded-solid-lipid-nanoparticles-plx-sln-characterization-of-physicochemical-properties-and-in-vitro-efficacy
#17
Patrícia Severino, Elisânia F Silveira, Kahynna Loureiro, Marco V Chaud, Danilo Antonini, Marcelo Lancellotti, Victor Hugo Sarmento, Classius F da Silva, Maria Helena A Santana, Eliana B Souto
Antimicrobial resistance is a current public health concern, limiting the available therapeutic options used for the treatment of common bacterial infections. The development of new drug entities via biotechnological processes is however expensive and time-consuming. Therefore, old antimicrobial agents have been recovered for clinical use. An example of these drugs is polymyxin, which is known for its serious adverse side effects, such as nephrotoxicity, neurotoxicity and promotion of skin pigmentation. To overcome these limitations, the use of biodegradable nanoparticles has been proposed to allow site-specific targeting, increasing the drug's bioavailability and decreasing its side effects...
May 30, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28574114/venlafaxine-intoxication-with-development-of-takotsubo-cardiomyopathy-successful-use-of-extracorporeal-life-support-intravenous-lipid-emulsion-and-cytosorb%C3%A2
#18
Ines Schroeder, Michael Zoller, Matthias Angstwurm, Felix Kur, Lorenz Frey
We describe a young patient who ingested 18 g (240 times the daily therapeutic dose) of venlafaxine in a suicide attempt. She developed severe cardiomyopathy in a takotsubo distribution causing cardiogenic shock and multi-organ dysfunction syndrome (MODS). She was successfully treated with intravenous lipid emulsion (ILE), extracorporeal life support (ECLS) and CytoSorb®. This is remarkable as, to the best of the authors' knowledge, this is the highest amount of venlafaxine intake seen in the literature with a nonfatal outcome...
May 23, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28566523/gastric-and-postgastric-processing-of-13-c-markers-renders-the-13-c-breath-test-an-inappropriate-measurement-method-for-the-gastric-emptying-of-lipid-emulsions-in-healthy-adults
#19
Helen L Parker, Dian Liu, Jelena Curcic, Marc-Olivier Ebert, Werner Schwizer, Michael Fried, Andreas Steingoetter
Background: Breath tests (BTs) present an alternative gastric-emptying (GE) measure. However, their efficacy in the measurement of the GE rate of lipid emulsions (LEs) is unknown.Objective: The objective of this work was to investigate the validity of (13)C BTs as a measure of fat GE rate in LEs.Methods: The lipophilic (13)C octanoate (OCC) BT marker was investigated for fat GE with the hydrophilic (13)C sodium acetate (ACC) and the triglyceride (13)C trioctanoin (TCC) markers as comparators. Data from 2 randomized studies were combined [50 healthy participants; 25 men, mean ± SD age: 23 ± 2...
May 31, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28565972/effects-of-insulin-glucose-pretreatment-on-bupivacaine-cardiotoxicity-in-rats
#20
Ö Pişkin, B G Aydın
A mistaken overdose of bupivacaine into systemic circulation may cause severe cardiovascular side effects. The aim of this study was to assess the effects of pretreatment with combined intra venous lipid emulsion (ILE) and high-dose insulin therapy against cardiotoxicity caused by bupivacaine intoxication. The rats were divided into the following three groups: Group B received a saline pretreatment plus a bupivacaine, group L received ILE pretreatment plus a bupivacaine, and in group I, insulin with glucose was infused intravenously, plus ILE pretreatment plus a bupivacaine...
January 1, 2017: Human & Experimental Toxicology
keyword
keyword
34726
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"