keyword
MENU ▼
Read by QxMD icon Read
search

Hogan

keyword
https://www.readbyqxmd.com/read/28650189/valuing-calm-enhances-enjoyment-of-calming-vs-exciting-amusement-park-rides-and-exercise
#1
Louise Chim, Candice L Hogan, Helene H H Fung, Jeanne L Tsai
Do people derive more enjoyment from activities that match how they ideally want to feel (their "ideal affect")? Affect valuation theory (AVT) predicts that they do; however, no study has directly examined whether this is the case. Therefore, the authors conducted 4 studies that examined whether valuing calm and other low arousal positive states (LAP) increased enjoyment of calming (vs. exciting) activities. In Study 1, the more participants valued LAP, the more enjoyment they recalled during calming (vs. exciting) episodes from their lives...
June 26, 2017: Emotion
https://www.readbyqxmd.com/read/28649891/new-targeted-therapies-for-relapsed-pediatric-lymphoblastic-leukemia
#2
Joanna Pierro, Laura E Hogan, Teena Bhatla, William L Carroll
The improvement in outcomes for children with acute lymphoblastic leukemia (ALL) is one of the greatest success stories of modern oncology however the prognosis for patients who relapse remains dismal. Recent discoveries by high resolution genomic technologies have characterized the biology of relapsed leukemia, most notably pathways leading to the drug resistant phenotype. These observations open the possibility of targeting such pathways to prevent and/or treat relapse. Likewise, early experiences with new immunotherapeutic approaches have shown great promise...
June 25, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28640244/systematic-design-and-comparison-of-expanded-carrier-screening-panels
#3
Kyle A Beauchamp, Dale Muzzey, Kenny K Wong, Gregory J Hogan, Kambiz Karimi, Sophie I Candille, Nikita Mehta, Rebecca Mar-Heyming, K Eerik Kaseniit, H Peter Kang, Eric A Evans, James D Goldberg, Gabriel A Lazarin, Imran S Haque
PurposeThe recent growth in pan-ethnic expanded carrier screening (ECS) has raised questions about how such panels might be designed and evaluated systematically. Design principles for ECS panels might improve clinical detection of at-risk couples and facilitate objective discussions of panel choice.MethodsGuided by medical-society statements, we propose a method for the design of ECS panels that aims to maximize the aggregate and per-disease sensitivity and specificity across a range of Mendelian disorders considered serious by a systematic classification scheme...
June 22, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28640195/pharmacogenomic-variants-may-influence-the-urinary-excretion-of-novel-kidney-injury-biomarkers-in-patients-receiving-cisplatin
#4
Cara Chang, Yichun Hu, Susan L Hogan, Nickie Mercke, Madeleine Gomez, Cindy O'Bryant, Daniel W Bowles, Blessy George, Xia Wen, Lauren M Aleksunes, Melanie S Joy
Nephrotoxicity is a dose limiting side effect associated with the use of cisplatin in the treatment of solid tumors. The degree of nephrotoxicity is dictated by the selective accumulation of cisplatin in renal tubule cells due to: (1) uptake by organic cation transporter 2 (OCT2) and copper transporter 1 (CTR1); (2) metabolism by glutathione S-transferases (GSTs) and γ-glutamyltransferase 1 (GGT1); and (3) efflux by multidrug resistance-associated protein 2 (MRP2) and multidrug and toxin extrusion protein 1 (MATE1)...
June 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28639997/parent-education-is-changing-a-review-of-smartphone-apps
#5
Deborah Winders Davis, M Cynthia Logsdon, Krista Vogt, Jeff Rushton, John Myers, Adrian Lauf, Felicia Hogan
PURPOSE: The purpose was to critique existing parenting apps using established criteria and health literacy guidelines. STUDY DESIGN: Descriptive methodology was used. METHODS: The Apple App Store was searched using the terms parenting, child health, and infant health. To be included, the apps had to have relevant content (parenting, child health, or infant health), be in English, and contain parent education. After eliminating apps that failed to meet inclusion criteria from the original 203 apps, 46 apps were reviewed...
June 20, 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28638073/plasmon-induced-selective-carbon-dioxide-conversion-on-earth-abundant-aluminum-cuprous-oxide-antenna-reactor-nanoparticles
#6
Hossein Robatjazi, Hangqi Zhao, Dayne F Swearer, Nathaniel J Hogan, Linan Zhou, Alessandro Alabastri, Michael J McClain, Peter Nordlander, Naomi J Halas
The rational combination of plasmonic nanoantennas with active transition metal-based catalysts, known as 'antenna-reactor' nanostructures, holds promise to expand the scope of chemical reactions possible with plasmonic photocatalysis. Here, we report earth-abundant embedded aluminum in cuprous oxide antenna-reactor heterostructures that operate more effectively and selectively for the reverse water-gas shift reaction under milder illumination than in conventional thermal conditions. Through rigorous comparison of the spatial temperature profile, optical absorption, and integrated electric field enhancement of the catalyst, we have been able to distinguish between competing photothermal and hot-carrier driven mechanistic pathways...
June 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28637440/acute-airway-compromise-due-to-parathyroid-tumour-apoplexy-an-exceptionally-rare-and-potentially-life-threatening-presentation
#7
Aoife Garrahy, David Hogan, James Paul O'Neill, Amar Agha
BACKGROUND: Spontaneous haemorrhage into a parathyroid adenoma is a rare and potentially life-threatening presentation. CASE PRESENTATION: We report the case of a 45 year old female recently diagnosed with primary hyperparathyroidism who presented with chest discomfort and acute airway compromise due to spontaneous extracapsular haemorrhage into a parathyroid adenoma. Computed tomography (CT) imaging showed a hypopharyngeal haematoma extending 10 cm into the superior mediastinum...
June 21, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28636467/normal-epithelial-cells-trigger-epha2-dependent-rasv12-cell-repulsion-at-the-single-cell-level
#8
William Hill, Catherine Hogan
Epithelial cells expressing oncogenic Ras (RasV12) are detected by normal neighbors and are often extruded from tissues. We recently demonstrated that differential EphA2 signaling drives the segregation of mutant cells from normal monolayers via cell repulsion and increased RasV12 cell contractility. EphA2 signaling on RasV12 cells is triggered by ephrin-A ligands presented by normal cells. Here, we show that normal epithelial cells trigger the repulsion and enhanced contractility of Ras-transformed epithelial cells at the single cell level...
June 21, 2017: Small GTPases
https://www.readbyqxmd.com/read/28632323/clinical-outcomes-of-hla-dpb1-mismatches-in-10-10-hla-matched-unrelated-donor-recipient-pairs-undergoing-allogeneic-stem-cell-transplant
#9
Ann M Moyer, Shahrukh K Hashmi, Cynthia M Kroning, Walter K Kremers, Steven R De Goey, Mrinal Patnaik, Mark Litzow, Dennis A Gastineau, William J Hogan, Eapen K Jacob, Justin D Kreuter, Laurie L Wakefield, Manish J Gandhi
OBJECTIVE: HLA-DPB1 matching may impact allogeneic hematopoietic stem cell transplantation (ASCT) outcomes; however, this locus is not in linkage disequilibrium with the remainder of the HLA genes. After classifying HLA-DPB1 mismatches based on T-cell epitope, avoiding non-permissive mismatches may impact survival. We tested this hypothesis at a single academic institution. METHODS: Retrospective HLA-DPB1 genotyping was performed on 153 adult patients who underwent ASCT and unrelated donors matched for HLA-A, B, C, DRB1 and DQB1 loci (10/10)...
June 20, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28630307/nanophotonics-enabled-solar-membrane-distillation-for-off-grid-water-purification
#10
Pratiksha D Dongare, Alessandro Alabastri, Seth Pedersen, Katherine R Zodrow, Nathaniel J Hogan, Oara Neumann, Jinjian Wu, Tianxiao Wang, Akshay Deshmukh, Menachem Elimelech, Qilin Li, Peter Nordlander, Naomi J Halas
With more than a billion people lacking accessible drinking water, there is a critical need to convert nonpotable sources such as seawater to water suitable for human use. However, energy requirements of desalination plants account for half their operating costs, so alternative, lower energy approaches are equally critical. Membrane distillation (MD) has shown potential due to its low operating temperature and pressure requirements, but the requirement of heating the input water makes it energy intensive. Here, we demonstrate nanophotonics-enabled solar membrane distillation (NESMD), where highly localized photothermal heating induced by solar illumination alone drives the distillation process, entirely eliminating the requirement of heating the input water...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28622234/the-authors-reply
#11
Gerard F Curley, Mirjana Jerkic, Grace Hogan, Claire Masterson, Daniel O'Toole, James Devaney, John G Laffey
No abstract text is available yet for this article.
July 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28619820/soxf-factors-induce-notch1-expression-via-direct-transcriptional-regulation-during-early-arterial-development
#12
Ivy Kim-Ni Chiang, Martin Fritzsche, Cathy Pichol-Thievend, Alice Neal, Kelly Holmes, Anne Lagendijk, Jeroen Overman, Donatella D'Angelo, Alice Omini, Dorien Hermkens, Emmanuelle Lesieur, Ke Liu, Indrika Ratnayaka, Monica Corada, George Bou-Gharios, Jason Carroll, Elisabetta Dejana, Stefan Schulte-Merker, Benjamin Hogan, Monica Beltrame, Sarah De Val, Mathias Francois
Arterial specification and differentiation are influenced by a number of regulatory pathways. While it is known that the Vegfa-Notch cascade plays a central role in this biological process, the transcriptional hierarchy controlling arterial specification has not been fully delineated. To elucidate the direct transcriptional regulators of Notch receptor expression in arterial endothelial cells, we used histone signatures, DNaseI hypersensitivity and ChIP-seq data to identify enhancers for the human NOTCH1 and zebrafish notch1b genes...
June 15, 2017: Development
https://www.readbyqxmd.com/read/28618034/computer-mediated-communication-in-intimate-relationships-associations-of-boundary-crossing-intrusion-relationship-satisfaction-and-partner-responsiveness
#13
Aaron M Norton, Joyce Baptist, Bernie Hogan
This study examined the impact of technology on couples in committed relationships through the lens of the couple and technology framework. Specifically, we used data from 6,756 European couples to examine associations between online boundary crossing, online intrusion, relationship satisfaction, and partner responsiveness. The results suggest that participants' reports of online boundary crossing were linked with lower relationship satisfaction and partner responsiveness. Also, lower relationship satisfaction and partner responsiveness were associated with increased online boundary crossing...
June 15, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28617751/economic-evaluations-of-strategies-to-prevent-hospital-acquired-pressure-injuries
#14
Wrechelle Ocampo, Amanda Cheung, Barry Baylis, Nancy Clayden, John M Conly, William A Ghali, Chester H Ho, Jaime Kaufman, Henry T Stelfox, David B Hogan
GENERAL PURPOSE: To provide information from a review of literature about economic evaluations of preventive strategies for pressure injuries (PIs). TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant should be better able to:1...
July 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28610128/review-of-i-pennella-i-oken-1816-copepoda-pennellidae-with-a-description-of-i-pennella-i-i-benzi-i-sp-nov-a-parasite-of-escolar-i-lepidocybium-i-i-flavobrunneum-i-pisces-in-the-northwest-atlantic-ocean
#15
W E Hogans
The genus Pennella Oken, 1816, mesoparasitic copepods from marine fish and mammals, is reviewed with the objective of determining the validity of members of the genus. Details of the external morphological structures of the adult female are presented. Pennella species are differentiated based on a combination of characters: the type of host parasitized, overall length of the parasite, shape, size and configuration of cephalothoracic papillae, segmentation of the first and second antenna, holdfast horn number, shape and configuration, and structure of the abdominal plumes...
March 17, 2017: Zootaxa
https://www.readbyqxmd.com/read/28606939/transcriptional-and-epigenetic-regulation-of-t-cell-hyporesponsiveness
#16
REVIEW
Renata M Pereira, Patrick G Hogan, Anjana Rao, Gustavo J Martinez
Naive CD8(+) T cells differentiate into effector and memory cytolytic T cells (CTLs) during an acute infection. In contrast, in scenarios of persistent antigen stimulation, such as chronic infections and cancer, antigen-specific CTLs show a gradual decrease in effector function, a phenomenon that has been termed CD8(+) T cell "exhaustion" or "dysfunction." Another hyporesponsive state, termed anergy, is observed when T cells are activated in the absence of positive costimulatory signals. Among the many negative regulators induced in hyporesponsive T cells are inhibitory cell-surface receptors, such as PD-1, LAG-3, CTLA-4, and TIM-3; "checkpoint blockade" therapies that involve treatment of patients with cancer with blocking antibodies to those receptors show considerable promise in the clinic because the blocking antibodies can mitigate hyporesponsiveness and promote tumor rejection...
June 12, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28604704/thermoneutral-housing-exacerbates-nonalcoholic-fatty-liver-disease-in-mice-and-allows-for-sex-independent-disease-modeling
#17
Daniel A Giles, Maria E Moreno-Fernandez, Traci E Stankiewicz, Simon Graspeuntner, Monica Cappelletti, David Wu, Rajib Mukherjee, Calvin C Chan, Matthew J Lawson, Jared Klarquist, Annika Sünderhauf, Samir Softic, C Ronald Kahn, Kerstin Stemmer, Yoichiro Iwakura, Bruce J Aronow, Rebekah Karns, Kris A Steinbrecher, Christopher L Karp, Rachel Sheridan, Shiva K Shanmukhappa, Damien Reynaud, David B Haslam, Christian Sina, Jan Rupp, Simon P Hogan, Senad Divanovic
Nonalcoholic fatty liver disease (NAFLD), a common prelude to cirrhosis and hepatocellular carcinoma, is the most common chronic liver disease worldwide. Defining the molecular mechanisms underlying the pathogenesis of NAFLD has been hampered by a lack of animal models that closely recapitulate the severe end of the disease spectrum in humans, including bridging hepatic fibrosis. Here we demonstrate that a novel experimental model employing thermoneutral housing, as opposed to standard housing, resulted in lower stress-driven production of corticosterone, augmented mouse proinflammatory immune responses and markedly exacerbated high-fat diet (HFD)-induced NAFLD pathogenesis...
June 12, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28604222/-express-primary-sensory-neuron-specific-interference-of-trpv1-signaling-by-aav-encoded-trpv1-peptide-aptamer-attenuates-neuropathic-pain
#18
Hongfei Xiang, Zhen Liu, Fei Wang, Hao Xu, Christopher Roberts, Gregory Fischer, Cheryl Stucky, Dean Caron, Bin Pan, Quinn Hogan, Hongwei Yu
No abstract text is available yet for this article.
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28597967/anidulafungin-for-the-treatment-of-candidaemia-caused-by-candida-parapsilosis-analysis-of-pooled-data-from-six-prospective-clinical-studies
#19
Dimitrios P Kontoyiannis, Matteo Bassetti, Marcio Nucci, Maria Rita Capparella, Jean L Yan, Jalal Aram, Patricia A Hogan
Concerns with echinocandin use for infections caused by Candida parapsilosis complex species have driven the need for data to support echinocandin clinical efficacy in such patients. Data from six prospective studies were pooled to assess efficacy and safety of anidulafungin in patients with candidaemia caused by C. parapsilosis. Patient-level data were pooled from patients with microbiologically confirmed candidaemia due to C. parapsilosis treated with anidulafungin. Patients received a 200 mg intravenous (IV) loading dose of anidulafungin (day 1) and 100 mg daily thereafter...
June 9, 2017: Mycoses
https://www.readbyqxmd.com/read/28585919/transcriptional-networks-specifying-homeostatic-and-inflammatory-programs-of-gene-expression-in-human-aortic-endothelial-cells
#20
Nicholas T Hogan, Michael B Whalen, Lindsey K Stolze, Nizar K Hadeli, Michael T Lam, James R Springstead, Christopher K Glass, Casey E Romanoski
Endothelial cells (ECs) are critical determinants of vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities and functional states remain poorly understood. Here, we report a genome-wide assessment of regulatory landscapes of primary human aortic endothelial cells (HAECs) under basal and activated conditions, enabling inference of transcription factor networks that direct homeostatic and pro-inflammatory programs. We demonstrate that 43% of detected enhancers are EC-specific and contain SNPs associated to cardiovascular disease and hypertension...
June 6, 2017: ELife
keyword
keyword
34721
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"