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https://www.readbyqxmd.com/read/29759045/neuropathological-developments-in-sudden-infant-death-syndrome
#1
Fiona M Bright, Robert Vink, Roger W Byard
A wide variety of neuropathological abnormalities have been investigated in infants who have died of sudden infant death syndrome (SIDS). Issues which detracted from early studies included failure to use uniform definitions of SIDS and lack of appropriately matched control populations. Development of the triple risk model focused attention on the concept of an inherent susceptibility to unexpected death in certain infants, with research demonstrating a role for the neurotransmitter serotonin within the brainstem...
January 1, 2018: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29720407/diagnostic-potential-of-stored-dried-blood-spots-for-inborn-errors-of-metabolism-a-metabolic-autopsy-of-medium-chain-acyl-coa-dehydrogenase-deficiency
#2
Noriyuki Kaku, Kenji Ihara, Yuichiro Hirata, Kenji Yamada, Sooyoung Lee, Hikaru Kanemasa, Yoshitomo Motomura, Haruhisa Baba, Tamami Tanaka, Yasunari Sakai, Yoshihiko Maehara, Shouichi Ohga
AIM: It is estimated that 1-5% of sudden infant death syndrome (SIDS) cases might be caused by undiagnosed inborn errors of metabolism (IEMs); however, the postmortem identification of IEMs remains difficult. This study aimed to evaluate the usefulness of dried blood spots (DBSs) stored after newborn screening tests as a metabolic autopsy to determine the causes of death in infants and children who died suddenly and unexpectedly. METHODS: Infants or toddlers who had suddenly died without a definite diagnosis between July 2008 and December 2012 at Kyushu University Hospital in Japan were enrolled in this study...
May 2, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29712764/the-grief-of-mothers-after-the-sudden-unexpected-death-of-their-infants
#3
Richard D Goldstein, Ruth I Lederman, Wendy G Lichtenthal, Sue E Morris, Melanie Human, Amy J Elliott, Deb Tobacco, Jyoti Angal, Hein Odendaal, Hannah C Kinney, Holly G Prigerson
: media-1vid110.1542/5741323271001PEDS-VA_2017-3651 Video Abstract BACKGROUND: The loss of a child is associated with elevated grief severity, and sudden infant death syndrome (SIDS) is the leading cause of postneonatal mortality in the United States. The diagnosis of prolonged grief disorder (PGD) has gained broader acceptance and use. Little is known about PGD in mothers after SIDS. METHODS: Between May 2013 and July 2016, we assessed 49 SIDS-bereaved mothers living in informal settlements near Cape Town, South Africa, and on the Pine Ridge Indian Reservation and 359 SIDS-bereaved mothers affiliated with SIDS parent-support organizations in the United States, United Kingdom, Australia, New Zealand, and the Netherlands...
April 30, 2018: Pediatrics
https://www.readbyqxmd.com/read/29668190/bedsharing-at-home-breastfeeding-and-sudden-infant-death-recommendations-for-health-professionals
#4
Alejandro Jenik, Roxana Conti
The Sudden and Unexpected Infant Death Task Force together with the Subcommittee on Breastfeeding of the Sociedad Argentina de Pediatría have issued updated recommendations on bedsharing with the parents, a practice which remains controversial. Sleeping with the mother maximizes breastfeeding, which is protective against Sudden Infant Death. There is a small group of infants that have been associated with an increased risk of Sudden Infant Death and fatal sleeping accidents in certain circumstances. These hazards include parental smoking, sedating drugs or medication and alcohol consumption prior to sleep and sofa sharing situations...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29666137/the-french-prospective-multisite-registry-on-sudden-unexpected-infant-death-omin-rationale-and-study-protocol
#5
Karine Levieux, Hugues Patural, Inge Harrewijn, Elisabeth Briand Huchet, Sophie de Visme, Géraldine Gallot, Martin Chalumeau, Christèle Gras Le Guen, Matthieu Hanf
INTRODUCTION: Even after 'back-to-sleep' campaigns, sudden unexpected infant death (SUID) continues to be the leading cause of death for infants 1 month to 1 year old in developed countries, with devastating social, psychological and legal implications for families. To sustainably tackle this problem and decrease the number of SUIDs, a French SUID registry was initiated in 2015 to (1) inform prevention with standardised data, (2) understand the mechanisms leading to SUID and the contribution of the already known or newly suggested risk factors and (3) gather a multidisciplinary group of experts to coordinate and develop innovative and urgent research in the SUID area...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29606014/analysis-of-sudden-infant-death-syndrome-coverage-in-canadian-newspapers
#6
Sadia Ahmed, Ian Mitchell, Gregor Wolbring
Sudden infant death syndrome (SIDS; also known as crib death) describes the sudden unexpected death of an infant under one year of age, which remains unexplained after a thorough investigation. SIDS is a public health concern. It is the fourth leading cause of infant death in Canada. Newspapers are a major source of health information for the public, shape public perceptions and can direct the discussion around issues. Despite the potential influence of newspapers, no study has examined the portrayal of SIDS in Canadian newspapers over time...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29601638/undiagnosed-congenital-heart-defects-as-a-cause-of-sudden-unexpected-death-in-children
#7
Serenella Serinelli, Ponni Arunkumar, Steven White
Despite advances in the diagnosis and treatment of congenital heart defects (CHDs), these defects are still an important cause of sudden, unexpected death in young children. This retrospective study identified 64 cases of CHDs presenting as a cause of sudden, unexpected death in a busy, urban Medical Examiner's Office pediatric population between 2006 and 2016. The majority of cases (52 of 64, 81%) were infants. Interestingly, 52% of cases were undiagnosed prior to autopsy. Ventricular septal defects and atrioventricular septal defects were the most common simple (14%) and complex (17%) malformations observed, respectively...
March 30, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29558846/focal-congenital-hyperinsulinism-as-a-cause-for-sudden-infant-death
#8
Amish Chinoy, Indraneel Banerjee, Sarah E Flanagan, Sian Ellard, Bing Han, Zainab Mohamed, Mark J Dunne, Stefania Bitetti
Congenital hyperinsulinism (CHI) is the commonest cause of persistent and severe hypoglycemia in infancy due to unregulated insulin secretion from pancreatic β-cells. Prompt early diagnosis is important, as insulin reduces glucose supply to the brain, resulting in significant brain injury and risk of death. Histologically, CHI has focal and diffuse forms; in focal CHI, an inappropriate level of insulin is secreted from localized β-cell hyperplasia. We report a 4-month-old male infant, who presented with sudden illness and collapse without a recognized cause and died...
January 1, 2018: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29558463/causes-of-death-and-infant-mortality-rates-among-full-term-births-in-the-united-states-between-2010-and-2012-an-observational-study
#9
Neha Bairoliya, Günther Fink
BACKGROUND: While the high prevalence of preterm births and its impact on infant mortality in the US have been widely acknowledged, recent data suggest that even full-term births in the US face substantially higher mortality risks compared to European countries with low infant mortality rates. In this paper, we use the most recent birth records in the US to more closely analyze the primary causes underlying mortality rates among full-term births. METHODS AND FINDINGS: Linked birth and death records for the period 2010-2012 were used to identify the state- and cause-specific burden of infant mortality among full-term infants (born at 37-42 weeks of gestation)...
March 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29538785/sudden-infant-death-syndrome-a-review
#10
Neal Goldberg, Yahdira Rodriguez-Prado, Rebecca Tillery, Caroline Chua
Sudden infant death syndrome (SIDS) is the sudden unexpected death of an apparently healthy infant younger than age 12 months whose cause of death remains unknown despite a thorough death scene investigation, a review of the clinical history, and an autopsy. Despite the huge achievement of the Back to Sleep program, SIDS remains one of the leading causes of infant death in the United States. In recent years, the SIDS rate has remained stationary despite major public health efforts aimed at high-risk groups to improve sleep environment and strategies...
March 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29496389/congenital-anomalies-of-the-coronary-arteries
#11
REVIEW
Andrea Silva, Maria João Baptista, Emanuel Araújo
Congenital coronary artery anomalies are modifications of their origin, course or structure and its incidence varies between 0,2 and 5,6% of the general population. Although the majority is asymptomatic, they are the second leading cause of sudden cardiac death in young athletes. The aim of this study is to highlight the main anomalies with hemodynamic significance, including the anomalous origin of a coronary artery from the opposite sinus and anomalous origin of the left coronary artery from pulmonary artery...
April 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29479813/sudden-infant-death-and-sleep-practices-in-the-black-community
#12
Deborah Stiffler, Brook Ayres, Cheyenne Fauvergue, Deborah Cullen
PURPOSE: A Black infant dies every 13 hours in the state of Indiana. The overall infant mortality rate in 2013 was 7.2 deaths per 1000 live births, but for Black infants, the rate was 15.3 deaths per 1000 live births. For over 20 years, placing an infant to sleep on his back has decreased the death rate from sudden unexpected infant death (SUID) and sudden infant death syndrome (SIDS), but many Black families continue to advocate bed sharing, prone sleeping, and inappropriate bedding/sleep surfaces, predisposing an infant to a significantly higher risk for SUID/SIDS...
April 2018: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29460253/neuronal-apoptosis-in-the-brainstem-medulla-of-sudden-unexpected-death-in-infancy-sudi-and-the-importance-of-standardized-sudi-classification
#13
Natalie Ambrose, Karen A Waters, Michael L Rodriguez, Kendall Bailey, Rita Machaalani
The purpose of this study was to examine the neuronal expression of apoptotic markers in the rostral medulla of a newly characterized dataset of sudden unexpected death in infancy (SUDI), and to determine the impact of diagnostic groupings on these findings and whether they pertain to the intrinsic apoptotic pathway. Immunohistochemical staining was quantified to determine the percentage of neurons positive for active caspase-9 (specific to the intrinsic apoptotic pathway), active caspase-3 (common to the intrinsic and extrinsic apoptotic pathways) and Terminal deoxynucleotidyl transferase mediated dUTP nick-end labelling (TUNEL) (labels DNA fragmentation) in nine nuclei of the rostral medulla...
March 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29452740/trends-in-the-incidence-of-sudden-unexpected-infant-death-in-the-newborn-1995-2014
#14
Joel L Bass, Tina Gartley, David A Lyczkowski, Ronald Kleinman
OBJECTIVE: To evaluate the epidemiology of sudden unexpected infant death (SUID) over a 20-year period in the US, to assess the potential frequency of sudden unexpected postnatal collapse in the early days of life, and to determine if SUID rates in the neonatal period (0-27 days) have changed in parallel with rates in the postneonatal periods, including the percentages attributed to codes that include accidental suffocation. STUDY DESIGN: Data from the US Centers for Disease Control and Prevention Linked Birth/Infant Death Records for 1995-2014 were analyzed for the first hour, day, week, and month of life...
May 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29440504/national-and-state-trends-in-sudden-unexpected-infant-death-1990-2015
#15
Alexa B Erck Lambert, Sharyn E Parks, Carrie K Shapiro-Mendoza
BACKGROUND: Sharp declines in sudden unexpected infant death (SUID) in the 1990s and a diagnostic shift from sudden infant death syndrome (SIDS) to unknown cause and accidental suffocation and strangulation in bed (ASSB) in 1999-2001 have been documented. We examined trends in SUID and SIDS, unknown cause, and ASSB from 1990 to 2015 and compared state-specific SUID rates to identify significant trends that may be used to inform SUID prevention efforts. METHODS: We used data from US mortality files to evaluate national and state-specific SUID rates (deaths per 100 000 live births) for 1990-2015...
February 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29440503/learning-from-national-and-state-trends-in-sudden-unexpected-infant-death
#16
Rebecca Carlin, Rachel Y Moon
No abstract text is available yet for this article.
February 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29439297/state-of-south-dakota-s-child-2017
#17
Ann L Wilson, Tyler Hemmingson, Brad Randall
There was a slight decrease in 2016 from 2015 in the total number of live births in South Dakota, but it was the fifth consecutive year that there were more than 12,000 newborns in the state. Nearly one-quarter of South Dakota's births represent minority populations mirroring what is observed nationally. Infant mortality in South Dakota dropped to its lowest ever rate per 1,000 live births (4.8) in 2016. Fewer births of less than 500 g newborns, increased survival of very low birth weight newborns, and a decrease in deaths due to congenital anomalies contributed to this low mortality rate...
January 2018: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/29429858/-neuropathology-of-sudden-infant-death-syndrome-review-of-the-literature-and-proposal-of-a-protocol-for-neuropathological-examination
#18
Clémence Delteil, David Meyronet, Andre Maues de Paula, Anne Jouvet, Marie-Dominique Piercecchi-Marti
According to the French High Authority for Health, sudden unexpected death in infants (SUDI) is defined as "a sudden death that occurs in an infant, whereas nothing in its known history could have predicted it". This is an exclusion diagnosis. There are great interregional disparities despite the professional recommendations established in February 2007. For the examination of the brain, instructions are not adapted to current and research practice. The role of the pathologist, like anyone involved in SUDI, is to eliminate an abuse head trauma and to determine the cause of death...
April 2018: Annales de Pathologie
https://www.readbyqxmd.com/read/29423392/neurochemical-alterations-in-sudden-unexplained-perinatal-deaths-a-review
#19
REVIEW
Nazeer Muhammad, Muhammad Sharif, Javeria Amin, Riffat Mehboob, Syed Amir Gilani, Nargis Bibi, Hasnain Javed, Naseer Ahmed
Sudden unexpected perinatal collapse is a major trauma for the parents of victims. Sudden infant death syndrome (SIDS) is unexpected and mysterious death of an apparently healthy neonate from birth till 1 year of age without any known causes, even after thorough postmortem investigations. However, the incidence of sudden intrauterine unexplained death syndrome (SIUDS) is seven times higher as compared with SIDS. This observation is approximated 40-80%. Stillbirth is defined as death of a fetus after 20th week of gestation or just before delivery at full term without a known reason...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29395889/sudden-unexpected-infant-death-time-for-integrative-national-registries
#20
EDITORIAL
K Levieux, H Patural, I Harrewijn, E Briand Huchet, B Kugener, O Pidoux, S de Visme, C Adjaoud, C Gras Le Guen, M Hanf
No abstract text is available yet for this article.
February 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
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