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https://www.readbyqxmd.com/read/28663329/long-qt-syndrome-and-sudden-unexpected-infant-death
#1
EDITORIAL
Chantal Van Niekerk, Barbara Ströh Van Deventer, Lorraine du Toit-Prinsloo
Long QT syndrome (LQTS) is an inheritable primary electric disease of the heart characterised by abnormally long QT intervals and a propensity to develop atrial and ventricular tachyarrhythmias. It is caused by an inherited channelopathy responsible for sudden cardiac death in individuals with structurally normal hearts. Long QT syndrome can present early in life, and some studies suggest that it may be associated with up to 20% of sudden unexplained infant death (SUID), particularly when associated with external stressors such as asphyxia, which is commonly seen in many infant death scenes...
June 29, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28562272/racial-and-ethnic-trends-in-sudden-unexpected-infant-deaths-united-states-1995-2013
#2
Sharyn E Parks, Alexa B Erck Lambert, Carrie K Shapiro-Mendoza
BACKGROUND AND OBJECTIVES: Immediately after the 1994 Back-to-Sleep campaign, sudden unexpected infant death (SUID) rates decreased dramatically, but they have remained relatively stable (93.4 per 100 000 live births) since 2000. In this study, we examined trends in SUID rates and disparities by race/ethnicity since the Back-to-Sleep campaign. METHODS: We used 1995-2013 US period-linked birth-infant death data to evaluate SUID rates per 100 000 live births by non-Hispanic white (NHW), non-Hispanic black (NHB), Hispanic, American Indian/Alaska Native, and Asian/Pacific Islander racial/ethnic groupings...
May 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28499698/dental-microwear-and-pliocene-paleocommunity-ecology-of-bovids-primates-rodents-and-suids-at-kanapoi
#3
Peter S Ungar, Elicia F Abella, Jenny H E Burgman, Ignacio A Lazagabaster, Jessica R Scott, Lucas K Delezene, Fredrick K Manthi, J Michael Plavcan, Carol V Ward
Reconstructions of habitat at sites like Kanapoi are key to understanding the environmental circumstances in which hominins evolved during the early Pliocene. While Australopithecus anamensis shows evidence of terrestrial bipedality traditionally associated with a more open setting, its enamel has low δ(13)C values consistent with consumption of C3 foods, which predominate in wooded areas of tropical Africa. Habitat proxies, ranging from paleosols and their carbonates to associated herbivore fauna and their carbon isotope ratios, suggest a heterogeneous setting with both grass and woody plant components, though the proportions of each have been difficult to pin down...
May 9, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28490705/-spatial-distribution-and-clustering-in-birth-defects-from-2010-to-2013-in-shaanxi-province
#4
Ruhai Bai, Lingling Wang, Qi Zhang, Shaonong Dang, Baibing Mi, Hong Yan
To explore the spatial distribution and clustering in birth defects from 2010 to 2013 in Shaanxi Province.
 Methods: Spatial distribution was used to describe the birth defects, while ordinary Kriging method was used to predict the status of birth defects in Shaanxi province. The spatial characteristics for the birth defects at the county/district level were analyzed by spatial autocorrelation.
 Results: The overall incidence of birth defects was 219.196/10 000; Birth defect did not appear to be a random distribution but show a significant spatial aggregation...
April 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28489063/african-swine-fever-virus-a-review
#5
REVIEW
Inmaculada Galindo, Covadonga Alonso
African swine fever (ASF) is a highly contagious viral disease of swine which causes high mortality, approaching 100%, in domestic pigs. ASF is caused by a large, double stranded DNA virus, ASF virus (ASFV), which replicates predominantly in the cytoplasm of macrophages and is the only member of the Asfarviridae family, genus Asfivirus. The natural hosts of this virus include wild suids and arthropod vectors of the Ornithodoros genus. The infection of ASFV in its reservoir hosts is usually asymptomatic and develops a persistent infection...
May 10, 2017: Viruses
https://www.readbyqxmd.com/read/28477233/deletion-of-the-us7-and-us8-genes-of-pseudorabies-virus-exerts-a-differential-effect-on-the-expression-of-early-and-late-viral-genes
#6
Nándor Póka, Zsolt Csabai, Emese Pásti, Dóra Tombácz, Zsolt Boldogkői
The pseudorabies virus (PRV; also known as Suid herpesvirus-1) is a neurotropic herpesvirus of swine. The us7 and us8 genes of this virus encode the glycoprotein I and E membrane proteins that form a heterodimer that is known to control cell-to-cell spread in tissue culture and in animals. In this study, we investigated the effect of the deletion of the PRV us7 and us8 genes on the genome-wide transcription and DNA replication using a multi-time-point quantitative reverse transcriptase-based real-time PCR technique...
August 2017: Virus Genes
https://www.readbyqxmd.com/read/28300151/insights-into-early-pig-domestication-provided-by-ancient-dna-analysis
#7
Amke Caliebe, Almut Nebel, Cheryl Makarewicz, Michael Krawczak, Ben Krause-Kyora
Pigs (Sus scrofa) were first domesticated between 8,500 and 8,000 cal BC in the Near East, from where they were subsequently brought into Europe by agriculturalists. Soon after the arrival of the first domestic pigs in northern Europe (~4500 BC), farmers are thought to have started to incorporate local wild boars into their swine herds. This husbandry strategy ultimately resulted in the domestication of European wild boars. Here, we set out to provide a more precise geographic and temporal framework of the early management of suid populations in northern Europe, drawing upon mitochondrial DNA haplotype data from 116 Neolithic Sus specimens...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28061875/regional-level-risk-factors-associated-with-the-occurrence-of-african-swine-fever-in-west-and-east-africa
#8
Zheng Y X Huang, Frank van Langevelde, Karanina J Honer, Marc Naguib, Willem F de Boer
BACKGROUND: African swine fever (ASF) causes severe socio-economic impacts due to high mortality and trade restrictions. Many risk factors of ASF have been identified at farm level. However, understanding the risk factors, especially wild suid hosts, determining ASF transmission at regional level remains limited. METHODS: Based on ASF outbreak data in domestic pigs during 2006-2014, we here tested, separately for West and East Africa, which risk factors were linked to ASF presence at a regional level, using generalized linear mixed models...
January 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28056966/pseudorabies-virus-infection-aujeszky-s-disease-in-an-iberian-lynx-lynx-pardinus-in-spain-a-case-report
#9
A Javier Masot, María Gil, David Risco, Olga M Jiménez, José I Núñez, Eloy Redondo
BACKGROUND: The only natural hosts of Pseudorabies virus (PRV) are members of the family Suidae (Sus scrofa scrofa). In species other than suids infection is normally fatal. In these mammals, including carnivores, PRV typically causes serious neurologic disease. The endangered Iberian lynx (Lynx pardinus) is a wild feline endemic to south-western Europe (Iberian Peninsula). The Iberian lynx was found to be the world's most endangered felid species in 2002. In wild felines, PRV infection has only been previously reported once in a Florida panther in 1994...
January 5, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/27995620/inner-ear-development-in-cetaceans
#10
Tara Thean, Nikolay Kardjilov, Robert J Asher
Cetaceans face the challenge of maintaining equilibrium underwater and obtaining sensory input within a dense, low-visibility medium. The cetacean ear represents a key innovation that marked their evolution from terrestrial artiodactyls to among the most fully aquatic mammals in existence. Using micro-CT and histological data, we document shape and size changes in the cetacean inner ear during ontogeny, and demonstrate that, as a proportion of gestation time, the cetacean inner ear is precocial in its growth compared with that of suid artiodactyls...
December 20, 2016: Journal of Anatomy
https://www.readbyqxmd.com/read/27908993/whole-genome-sequence-of-a-suid-herpesvirus-1-strain-isolated-from-the-brain-of-a-hunting-dog-in-italy
#11
Federica Pizzurro, Iolanda Mangone, Guendalina Zaccaria, Eliana De Luca, Daniela Malatesta, Marco Innocenti, Irene Carmine, Francesca Cito, Maurilia Marcacci, Daria Di Sabatino, Alessio Lorusso
Suid herpesvirus-1 (SHV-1), a DNA virus of the family Herpesviridae, causes a severe and fatal disease in a wide range of mammals. Here, we report the whole-genome sequence of an SHV-1 isolated in Italy in 2014 from the brain of a hunting dog that suffered from an acute and severe disease.
December 1, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27899604/ipd-mhc-2-0-an-improved-inter-species-database-for-the-study-of-the-major-histocompatibility-complex
#12
Giuseppe Maccari, James Robinson, Keith Ballingall, Lisbeth A Guethlein, Unni Grimholt, Jim Kaufman, Chak-Sum Ho, Natasja G de Groot, Paul Flicek, Ronald E Bontrop, John A Hammond, Steven G E Marsh
The IPD-MHC Database project (http://www.ebi.ac.uk/ipd/mhc/) collects and expertly curates sequences of the major histocompatibility complex from non-human species and provides the infrastructure and tools to enable accurate analysis. Since the first release of the database in 2003, IPD-MHC has grown and currently hosts a number of specific sections, with more than 7000 alleles from 70 species, including non-human primates, canines, felines, equids, ovids, suids, bovins, salmonids and murids. These sequences are expertly curated and made publicly available through an open access website...
January 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/27891698/vaccination-and-unexplained-sudden-death-risk-in-taiwanese-infants
#13
Wan-Ting Huang, Robert T Chen, Yu-Chen Hsu, John W Glasser, Philip H Rhodes
PURPOSE: In March 1992, eight infants who had died within 36 hours of receiving whole-cell pertussis vaccine (diphtheria, tetanus, and whole-cell pertussis [DTwP]) prompted the Taiwan health authorities to suspend its use. We conducted an investigation of vaccination and sudden unexplained infant death (SUID) and repeated it more recently after Taiwan switched to acellular pertussis vaccine (diphtheria, tetanus, and acellular pertussis [DTaP]) in 2010. METHODS: All SUIDs aged 31-364 days during 1990-1992 and 1996-2013 were selected from the death registration databases...
November 28, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27855594/when-chems-meet-sex-a-rising-phenomenon-called-chemsex
#14
Raffaele Giorgetti, Adriano Tagliabracci, Fabrizio Schifano, Simona Zaami, Enrico Marinelli, Francesco Paolo Busardò
BACKGROUND: The term "chemsex" was coined to indicate the voluntary intake of psychoactive and non psychoactive drugs in the context of recreational settings to facilitate and/or to enhance sexual intercourses mostly among men who have sex with other men (MSM). OBJECTIVE: The authors aimed to review the mechanisms of action, the toxicity and the pattern of use and abuse of substances involved in "chemsex" practice together with the sociocultural background underlying it and the health-related consequences that they may have...
2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/27700037/icpms-based-specific-quantification-of-phosphotyrosine-a-gallium-tagging-and-tyrosine-phosphatase-mediated-strategy
#15
Nannan Tang, Zhaoxin Li, Limin Yang, Qiuquan Wang
Low-abundance tyrosine phosphorylation is crucial to not only normal but also aberrant life processes. We designed and synthesized a photocleavable magnetic nanoparticle-based gallium tag for tagging and enrichment as well as UV-release of the phosphate-bearing molecules/ions in cells. HPLC/(71)Ga species-unspecific isotope dilution ((71)Ga-SUID) ICP-MS was subsequently developed for specific and absolute quantification of phosphotyrosine (pY) under the assistance of a protein tyrosine phosphatase-1B (PTP-1B)...
October 4, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27677096/the-institution-of-a-standardized-investigation-protocol-for-sudden-infant-death-in-the-eastern-metropole-cape-town-south-africa
#16
Johan J Dempers, Jean Coldrey, Elsie H Burger, Vonita Thompson, Shabbir A Wadee, Hein J Odendaal, Mary Ann Sens, Brad B Randall, Rebecca D Folkerth, Hannah C Kinney
The rate for the sudden infant death syndrome (SIDS) in Cape Town, South Africa, is estimated to be among the highest in the world (3.41/1000 live births). In several of these areas, including those of extreme poverty, only sporadic, nonstandardized infant autopsy, and death scene investigation (DSI) occurred. In this report, we detail a feasibility project comprising 18 autopsied infants with sudden and unexpected death whose causes of death were adjudicated according to the 1991 NICHD definitions (SIDS, n = 7; known cause of death, n = 7; and unclassified, n = 4)...
November 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27667928/the-middle-pleistocene-vertebrate-fauna-from-khok-sung-nakhon-ratchasima-thailand-biochronological-and-paleobiogeographical-implications
#17
Kantapon Suraprasit, Jean-Jacques Jaeger, Yaowalak Chaimanee, Olivier Chavasseau, Chotima Yamee, Pannipa Tian, Somsak Panha
The fluviatile terrace deposits of Khok Sung, Nakhon Ratchasima province, have yielded more than one thousand fossils, making this the richest Pleistocene vertebrate fauna of Thailand. The excellent preservation of the specimens allows precise characterization of the faunal composition. The mammalian fauna consists of fifteen species in thirteen genera, including a primate, a canid, a hyaenid, proboscideans, rhinoceroses, a suid, cervids, and bovids. Most species correspond to living taxa but globally (Stegodon cf...
2016: ZooKeys
https://www.readbyqxmd.com/read/27649301/safe-sleep-infant-care-practices-reported-by-mothers-of-twins
#18
Elizabeth G Damato, Madeline C Haas, Pamela Czeck, Donna A Dowling, Sarah Gutin Barsman
BACKGROUND: The high prevalence of prematurity and low birth-weight places twin infants at increased risk for sudden unexpected infant death (SUID) and/or sudden infant death syndrome (SIDS). Risk for these SUID and SIDS is affected by a combination of nonmodifiable intrinsic risk factors and modifiable extrinsic stressors including infant care practices related to sleep. Although adherence to the full scope of American Academy of Pediatrics (AAP) 2011 recommendations is intended to decrease risk, these recommendations are aimed at singleton infants and may require tailoring for families with multiple infants...
December 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27633968/development-of-a-novel-lateral-flow-assay-for-detection-of-african-swine-fever-in-blood
#19
P Sastre, C Gallardo, A Monedero, T Ruiz, M Arias, A Sanz, P Rueda
BACKGROUND: African swine fever (ASF) is a viral infectious disease of domestic and wild suids of all breeds and ages, causing a wide range of hemorrhagic syndromes and frequently characterized by high mortality. The disease is endemic in Sub-Saharan Africa and Sardinia. Since 2007, it has also been present in different countries of Eastern Europe, where control measures have not been effective so far. The continued spread poses a serious threat to the swine industry worldwide. In the absence of vaccine, early detection of infected animals is of paramount importance for control of the outbreak, to prevent the transmission of the virus to healthy animals and subsequent spreading of the disease...
September 15, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27629027/untangling-the-environmental-from-the-dietary-dust-does-not-matter
#20
Gildas Merceron, Anusha Ramdarshan, Cécile Blondel, Jean-Renaud Boisserie, Noël Brunetiere, Arthur Francisco, Denis Gautier, Xavier Milhet, Alice Novello, Dimitri Pret
Both dust and silica phytoliths have been shown to contribute to reducing tooth volume during chewing. However, the way and the extent to which they individually contribute to tooth wear in natural conditions is unknown. There is still debate as to whether dental microwear represents a dietary or an environmental signal, with far-reaching implications on evolutionary mechanisms that promote dental phenotypes, such as molar hypsodonty in ruminants, molar lengthening in suids or enamel thickening in human ancestors...
September 14, 2016: Proceedings. Biological Sciences
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