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https://www.readbyqxmd.com/read/28427128/-the-application-value-of-contrast-enhanced-ultrasound-in-the-surgery-of-renal-masses
#1
M H Liu, J H Shi, Q M H Wangqi, Y Q Lin, Z X Sun
Objective: To investigate the clinical value of contrast-enhanced ultrasound in the diagnosis of renal masses. Methods: A total of 50 patients with renal masses who underwent partial nephrectomy were analyzed from January 2014 to October 2016 in the Department of Urology of China-Japan Union Hospital of Jilin University.In the intraoperative contrast-enhanced ultrasound, the characteristics of ultrasound imaging were recorded including location, size, boundary, echo, real-time internal and peripheral blood and renal pelvis distance, artery, guidance on the selection of surgical methods, intraoperative real-time estimation of the extent of tumor resection...
April 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28427029/treatment-of-refractory-and-super-refractory-status-epilepticus-with-brivaracetam-a-cohort-study-from-two-german-university-hospitals
#2
Adam Strzelczyk, Isabel Steinig, Laurent M Willems, Philipp S Reif, Christian Senft, Martin Voss, Bernadette Gaida, Felix von Podewils, Felix Rosenow
PURPOSE: We aimed to ascertain the possible use of brivaracetam (BRV) as an option for treatment of status epilepticus (SE). METHODS: A review of medical records was carried out to detect BRV administration in SE patients treated in Frankfurt and Greifswald during the period February 2016 to January 2017. The primary outcome question concerned SE resolution after BRV initiation. RESULTS: During that period, BRV was started with eleven adult patients with SE...
April 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28427022/stereotypy-of-psychogenic-nonepileptic-seizures
#3
Moshe Herskovitz
Psychogenic nonepileptic seizures (PNES) are defined as paroxysmal episodes in which epileptic semiology features are manifested, without the characteristic concomitant electrical discharges seen in epileptic seizures. Although many studies have dealt with semiologic classification of PNES, most of the studies did not raise the question of consistency of PNES in the same patient. The aim of this study was to measure the degree of consistency of PNES among individual patients. We retrospectively reviewed medical records and video- EEG records of all adult patients who underwent monitoring in our center from August 1st 2013 to May 31st 2015...
April 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28427016/synthesis-and-in%C3%A2-vitro-antitumour-activity-of-crassalactone-d-its-stereoisomers-and-novel-cinnamic-ester-derivatives
#4
Ivana Kovačević, Mirjana Popsavin, Goran Benedeković, Jelena Kesić, Vesna Kojić, Dimitar Jakimov, Tatjana Srdić-Rajić, Gordana Bogdanović, Vladimir Divjaković, Velimir Popsavin
Naturally occurring styryl lactone, crassalactone D (1), unnatural 4-epi-crassalactone D (2), and the corresponding 7-epimers (3 and 4) have been synthesized starting from d-glucose. The key step of the synthesis is a new one-pot sequence that commenced with a Z-selective Wittig olefination of suitably functionalized sugar lactols with a stabilized ylide, (methoxycarbonylmethylene)-triphenylphosphorane, in dry methanol, to afford 1 or 3, in the mixtures with the corresponding 4-epimers (2 or 4, respectively)...
April 13, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28426991/clinical-usefulness-of-18-f-fdg-pet-ct-for-initial-staging-and-assessment-of-treatment-efficacy-in-patients-with-lymph-node-tuberculosis
#5
Nicolas Lefebvre, Xavier Argemi, Nicolas Meyer, Joy Mootien, Nawal Douiri, Stefania Sferrazza-Mandala, Frédéric Schramm, Noëlle Weingertner, Daniel Christmann, Yves Hansmann, Alessio Imperiale
INTRODUCTION: Few studies have evaluated the promising role of (18)F-fluoro-2-deoxy-D-glucose positron emission tomography (PET) and PET/computed tomography FDG PET/CT in evaluating and monitoring treatment response in patients with lymph node tuberculosis (LNTB). The aim of this clinical investigation was to assess the clinical usefulness of FDG PET/CT for initial tuberculosis staging and to determine the prognostic value of the decrease of (18)F-FDG uptake during antibiotic treatment in LNTB patients...
April 8, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/28426745/objective-classification-of-zonular-weakness-based-on-lens-movement-at-the-start-of-capsulorhexis
#6
Saori Yaguchi, Shigeo Yaguchi, Yukari Yagi-Yaguchi, Tadahiko Kozawa, Hiroko Bissen-Miyajima
PURPOSE: To quantify zonular weakness based on lens movement at the start of continuous curvilinear capsulorhexis (CCC) and establish a classification system for it. SETTING: Kozawa Eye Hospital and Diabetes Center, Mito, Japan. DESIGN: Retrospective interventional case series. METHODS: We examined 402 consecutive eyes of 316 patients who underwent CCC, phacoemulsification and aspiration (PEA), and intraocular lens (IOL) implantation...
2017: PloS One
https://www.readbyqxmd.com/read/28426447/measles-cases-in-children-requiring-hospital-access-in-an-academic-pediatric-hospital-in-italy-2008-2013
#7
Marta Ciofi Degli Atti, Antonietta Filia, Antonino Bella, Annamaria Sisto, Maria Antonietta Barbieri, Antonino Reale, Massimiliano Raponi
BACKGROUND: The Lazio Region is one of the Italian regions where sustained measles transmission continues to occur. We investigated measles cases reported by the Emergency Department (ED) of the largest pediatric hospital in Italy, located in Lazio. METHODS: We reviewed clinical records of all measles cases from 0 to 18 years of age evaluated in the ED in 2008-2013. We compared demographic and clinical characteristics of patients admitted to the inpatient setting with those of patients discharged home, to assess possible determinants of hospital admission...
April 18, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28426389/melatonin-and-circadian-rhythms-in-autism-case-report
#8
Gabriela Melloni Zuculo, Bruno S B Gonçalves, Clay Brittes, Luiz Menna-Barreto, Luciana Pinato
Among the most co-occurring conditions in autism spectrum disorders (ASD), there are sleep disorders which may exacerbate associated behavioral disorders and lead to intensification of existing autistic symptoms. Several studies investigating the use of melatonin in the treatment of sleep disorders in ASD have shown comparative efficiency in sleep with little or no side effects. Here we report a case of ASD with non-24-hour rhythm and the effect of melatonin in circadian parameters by actigraphy. Visual analysis of the first 10 days recorded and the periodogram suggest that this patient showed a non-24-hour rhythm...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28426345/economic-evaluation-of-ezetimibe-treatment-in-combination-with-statin-therapy-in-the-united-states
#9
Glenn M Davies, Ami Vyas, Carl A Baxter
AIMS: This study assessed the cost-effectiveness of ezetimibe with statin therapy versus statin monotherapy from a United States (US) payer perspective, assuming the impending patent expiration of ezetimibe. METHODS: A Markov-like economic model consisting of 28 distinct health states was used. Model population data were obtained from US linked claims and electronic medical records, with inclusion criteria based on diagnostic guidelines. Inputs came from recent clinical trials, meta-analyses, and cost-effectiveness analyses...
April 20, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28426258/improvements-in-out-of-hospital-cardiac-arrest-survival-from-1998-to-2013
#10
Yutaka Yamaguchi, Jeff A Woodin, Koichiro Gibo, Dana M Zive, Mohamud R Daya
OBJECTIVES: Out-of-hospital cardiac arrest (OHCA) remains a major public health burden. Aggregate OHCA survival to hospital discharge has reportedly remained unchanged at 7.6% for almost 30 years from 1970 to 2008. We examined the trends in adult OHCA survival over a 16-year period from 1998 to 2013 within a single EMS agency. METHODS: Observational cohort study of adult OHCA patients treated by Tualatin Valley Fire & Rescue (TVF&R) from 1998 to 2013. This is an ALS first response fire agency that maintains an active Utstein style cardiac arrest registry and serves a population of approximately 450,000 in 9 incorporated cities in Oregon...
April 20, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28426243/analysis-of-2019-patients-undergoing-revision-anterior-cruciate-ligament-reconstruction-from-a-community-based-registry
#11
Afshin Arianjam, Maria C S Inacio, Tadashi T Funahashi, Gregory B Maletis
BACKGROUND: Knowledge of patient characteristics, surgical fixation, graft choice, outcomes, and concurrent injuries of revision anterior cruciate ligament reconstruction (ACLR) is limited. PURPOSE: To describe the current cohort of revision ACLR captured by a community registry and the outcomes observed in the registered patients. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Patients who underwent revision ACLR registered between February 2005 and June 2014, by 200 surgeons in 46 hospitals, were evaluated...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28426173/spinal-arachnoid-diverticula-outcome-in-96-dogs-medically-or-surgical-treated-dogs
#12
D A Mauler, S De Decker, L De Risio, H A Volk, R Dennis, I Gielen, E Van der Vekens, K Goethals, L Van Ham
BACKGROUND: Little is reported about the role of medical management in the treatment of spinal arachnoid diverticula (SAD) in dogs. OBJECTIVES: To describe the outcome of 96 dogs treated medically or surgically for SAD. ANIMALS: Ninety-six dogs with SAD. METHODS: Retrospective case series. Medical records were searched for spinal arachnoid diverticula and all dogs with information on treatment were included. Outcome was assessed with a standardized questionnaire...
April 20, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28426129/case-review-and-outcomes-of-prenatally-diagnosed-amniotic-sheets
#13
Assaad Kesrouani, Bernard Nasr, Habib Atallah, Samer Maalouf, Elie Chalhoub
The present study recorded a case series of 11 patients diagnosed with amniotic sheets at an outpatient obstetric clinic affiliated to Saint Joseph University, Beirut, Lebanon, between January 1, 2003, and December 31, 2013. Of these patients, nine were diagnosed during routine obstetric ultrasonography examination and two patients were referred from other centers. All patients included in the case series had singleton pregnancies and the mean length of pregnancy at diagnosis was 17 weeks (range 13-22). This article is protected by copyright...
April 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28426103/neurotoxicity-from-immune-checkpoint-inhibition-in-the-treatment-of-melanoma-a-single-centre-experience-and-review-of-the-literature
#14
L Spain, G Walls, M Julve, K O'Meara, T Schmid, E Kalaitzaki, S Turajlic, M Gore, J Rees, J Larkin
Background: Treatment with immune checkpoint inhibitors (ICPi) has greatly improved survival for patients with advanced melanoma in recent years. Anti-CTLA-4 and anti-PD1 antibodies have been approved following large Phase III trials. Immune-related neurological toxicity of varying severity has been reported in the literature. The cumulative incidence of neurotoxicity among ipilimumab, nivolumab and pembrolizumab is reported as <1% in published clinical trials. We aimed to identify the incidence of neurotoxicity in our institution across anti-CTLA4 and anti-PD-1 antibodies, including the combination of ipilimumab with nivolumab...
February 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28425758/agreement-between-mri-and-pathologic-analyses-for-determination-of-tumor-size-and-correlation-with-immunohistochemical-factors-of-invasive-breast-carcinoma
#15
Eun Young Yoo, Sang Yu Nam, Hye-Young Choi, Min Ji Hong
Background There may be discordance between tumor size determined by magnetic resonance imaging (MRI) and that observed during pathologic analyses. Purpose To evaluate MRI-pathology concordance of tumor size in patients with invasive breast carcinoma. Material and Methods Data from 307 invasive breast carcinomas were analyzed retrospectively. Preoperative breast MRI was reviewed for size, lesion type, morphology, and dynamic contrast-enhanced tumor kinetics. MRI tumor size was compared with tumor size measurements from the pathologic analysis...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28425726/comparisons-between-the-minnesota-multiphasic-personality-inventory-adolescent-restructured-form-mmpi-a-rf-and-mmpi-a-in-adolescent-psychiatric-inpatients
#16
John M Stokes, David L Pogge, Robert P Archer
This study explored the association between the Minnesota Multiphasic Personality Inventory (MMPI)-Adolescent-Restructured Form (MMPI-A-RF) and the MMPI-Adolescent (MMPI-A) form in a sample of 3,516 adolescents receiving inpatient psychiatric treatment, including 2,798 adolescents meeting validity inclusion cutoffs for both measures. There was 92.5% agreement rate with respect to global identification of cases as valid or invalid and some empirical support for lowering interpretive cutoffs for validity scales on the MMPI-A-RF...
April 20, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28425616/statin-use-and-risk-of-multiple-myeloma-an-analysis-from-the-cancer-research-network
#17
Mara M Epstein, George Divine, Chun R Chao, Karen E Wells, Heather Spencer Feigelson, Delia Scholes, Douglas Roblin, Marianne Ulcickas Yood, Lawrence S Engel, Andrew Taylor, Joan Fortuny, Laurel A Habel, Christine C Johnson
Animal and human data suggest statins may be protective against developing multiple myeloma; however, findings may be biased by the interrelationship with lipid levels. We investigated the association between statin use and risk of multiple myeloma in a large US population, with an emphasis on accounting for this potential bias. We conducted a case-control study nested within 6 US integrated healthcare systems participating in the National Cancer Institute-funded Cancer Research Network. Adults aged ≥40 years who were diagnosed with multiple myeloma from 1998-2008 were identified through cancer registries (N=2532)...
April 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28425610/bacterial-screening-of-platelet-components-by-national-health-service-blood-and-transplant-an-effective-risk-reduction-measure
#18
Carl McDonald, Jennifer Allen, Susan Brailsford, Anjana Roy, Joanne Ball, Richard Moule, Mariza Vasconcelos, Rachael Morrison, Tyrone Pitt
BACKGROUND: Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associated transmission of bacterial infection were recorded for 10 patients, three of which were fatal. STUDY DESIGN AND METHODS: Sampling of individual PLT components was undertaken at 36 to 48 hours after donation and tested in the BacT/ALERT system with 8 mL inoculated into each of aerobic and anaerobic culture bottles...
May 2017: Transfusion
https://www.readbyqxmd.com/read/28425423/pathology-and-molecular-analysis-of-hapalotrema-mistroides-digenea-spirorchiidae-infecting-a-mediterranean-loggerhead-turtle-caretta-caretta
#19
M Santoro, F Di Nocera, D Iaccarino, S P Lawton, A Cerrone, B Degli Uberti, M D'Amore, A Affuso, S Hochscheid, F Maffucci, G Galiero
Turtle blood flukes belonging to the family Spirorchiidae (Digenea) represent a major threat for sea turtle health and are considered the most important parasitic cause of turtle stranding and mortality worldwide. Despite the large diversity of spirorchiid species found globally, there are only 2 records for free-ranging Mediterranean sea turtles that date back to the late 1800s involving just Hapalotrema mistroides Monticelli, 1896. This study describes the first fatal confirmed case of spirorchiidiasis in a free-ranging Mediterranean loggerhead turtle Caretta caretta (Linnaeus) and, owing to the complexities of taxonomic identification of these parasites, provides the first molecular characterization and phylogenetic analysis of H...
April 20, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/28425414/cholangiohydatidosis-an-infrequent-cause-of-obstructive-jaundice-and-acute-cholangitis
#20
Carlos Manterola, Tamara Otzen
BACKGROUND: One of the evolutionary complications of hepatic echinococcosis (HE) is cholangiohydatidosis, a rare cause of obstructive jaundice and cholangitis. The aim of this study was to describe the results of surgical treatment on a group of patients with cholangiohydatidosis and secondary cholangitis in terms of post-operative morbidity (POM). MATERIAL AND METHOD: Case series of patients operated on for cholangiohydatidosis and cholangitis in the Department at Surgery of the Universidad de La Frontera and the Clínica Mayor in Temuco, Chile between 2004 and 2014...
May 2017: Annals of Hepatology
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