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Depression and elderly

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https://www.readbyqxmd.com/read/28087218/relationship-among-motor-function-adl-disability-and-psychological-concerns-in-elderly-people-with-locomotive-disorders
#1
Toshiyuki Miyawaki, Keigo Kumamoto, Kaori Shimoda, Fusae Tozato, Tsutomu Iwaya
BACKGROUND: Locomotive disorders are one of the main causative pathologies for the condition requiring assistance on activities of daily living (ADL). Although psychological concerns such as feeling of depression and anxiety are prevalent in elderly people, the causal relation among motor function, ADL disability, and psychological concerns is controversial. PURPOSE: Purpose of this study was to investigate causal relationship among motor function, ADL disability, and psychological concerns in elderly people with locomotive disorders...
January 10, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28079266/risk-of-mortality-in-elderly-nursing-home-patients-with-depression-using-paroxetine
#2
Vishal Bali, Satabdi Chatterjee, Michael L Johnson, Hua Chen, Ryan M Carnahan, Rajender R Aparasu
OBJECTIVE: Among selective serotonin reuptake inhibitors (SSRIs), paroxetine is strongly anticholinergic and might lead to higher risk of adverse outcomes such as mortality. This study examined the risk of mortality in depressed elderly nursing home patients using paroxetine and other SSRIs. METHODS: This study used 2007-2010 Minimum Data Set - linked Medicare data and propensity score-matched retrospective cohort study design to achieve the study objective. New users of paroxetine and other SSRIs were followed until they reached the end of the follow-up period (one year), switched to a different antidepressant class, used psychotherapy, or had a gap of more than 15 days in the use of index antidepressant class, whichever occurred earlier...
January 12, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28079228/attenuated-recovery-of-contractile-function-in-aging-hearts-following-global-ischemia-reperfusion-role-of-extracellular-hsp27-and-tlr4
#3
Lihua Ao, Yufeng Zhai, Chunhua Jin, Joseph C Cleveland, David A Fullerton, Xianzhong Meng
BACKGROUND: While cardiac functional recovery is attenuated in the elderly following cardiac surgery with obligatory global myocardial ischemia/reperfusion (I/R), the underlying mechanism remains incompletely understood. We observed previously that human and mouse myocardium releases heat shock protein (HSP) 27 during global I/R. Extracellular HSP27 induces myocardial inflammatory response and plays a role in post-ischemic cardiac dysfunction in adult mouse hearts. OBJECTIVE: This study was to determine the role of extracellular HSP27 and Toll-like receptor 4 (TLR4) in the attenuated functional recovery in aging mouse hearts following global I/R...
December 19, 2016: Molecular Medicine
https://www.readbyqxmd.com/read/28077832/-frailty-and-its-related-factors-in-vulnerable-elderly-population-by-age-groups
#4
Eunok Park, Mi Yu
PURPOSE: This study aimed to investigate factors affecting frailty by age groups among vulnerable elders in Korea. METHODS: In this secondary analysis, data were collected from records for 22,868 eldesr registered in the Visiting Health Management program of Publci Health Centers in 2012. Health behaviors, clinically diagnosed disease, frailty, depression and cognitive condition were assessed. Data were analyzed using stepwise regression to determine the associated factors of frailty by age group...
December 2016: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28077154/incremental-decreases-in-quality-adjusted-life-years-qaly-associated-with-higher-levels-of-depressive-symptoms-for-u-s-adults-aged-65-years-and-older
#5
Haomiao Jia, Erica I Lubetkin
BACKGROUND: Quality-adjusted life years (QALY) is a single value index that quantifies the overall burden of disease. It reflects all aspects of heath, including nonfatal illness and mortality outcomes by weighting life-years lived with health-related quality of life (HRQOL) scores. This study examine the burden of disease due to increasing levels of depressive symptoms by examining the association between the 9-item Patient Health Questionnaire (PHQ-9) scores and QALY for U.S. adults aged 65 years and older...
January 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28077141/determinants-of-and-socio-economic-disparities-in-self-rated-health-in-china
#6
Jiaoli Cai, Peter C Coyte, Hongzhong Zhao
BACKGROUND: Self-rated health (SRH) is not only used to measure health status and health inequalities, but also as a strong predictor of morbidity and mortality. The purpose of this study was to: 1) evaluate the factors that account for variations in self-rated health among Chinese citizens; and to 2) explore the process through which socio-economic status may impact self-rated health. METHODS: Data were derived from the Chinese General Social Survey (CGSS) (2013)...
January 11, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28076836/the-metabolic-syndrome-and-10-year-cognitive-and-functional-decline-in-very-old-men-a-population-based-study
#7
Giovanni Viscogliosi, Chiara Donfrancesco, Luigi Palmieri, Simona Giampaoli
OBJECTIVES: To describe longitudinal relationships of metabolic syndrome (MetS) to cognitive decline and functional disability in a sample of older non-institutionalized men. METHODS: data from 1991 to 2000 of the Italian cohorts of the Finland, Italy, the Netherlands, Elderly (FINE) study, were used. Global cognitive function and functional disability, defined as limitations in mobility, basic (ADLs) and instrumental activities of daily living (IADLs) were screened in 1991 and 2000...
January 3, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28075650/pharmacokinetic-evaluation-of-pregabalin-for-the-treatment-of-generalized-anxiety-disorder
#8
Massimiliano Buoli, Alice Caldiroli, Marta Serati
Pregabalin is an alternative compound to SSRIs and SNRIs for the first-line treatment of generalized anxiety disorder (GAD). Areas covered: We describe the pharmacokinetic properties of pregabalin and their implications for the treatment of GAD. A search in the main database sources (Medline, ISI, Web of Knowledge and Medscape) was performed in order to obtain a comprehensive and balanced evaluation about the clinical implications of the pharmacokinetic properties of pregabalin in the treatment of GAD. The word "pregabalin" was associated with "pharmacokinetics", "interactions"', "GAD", "anxiety" and "tolerability"...
January 11, 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/28068553/the-relationship-of-community-activities-with-cognitive-impairment-and-depressive-mood-independent-of-mobility-disorder-in-japanese-older-adults
#9
Mika Okura, Mihoko Ogita, Miki Yamamoto, Toshimi Nakai, Tomoko Numata, Hidenori Arai
AIM: This study aimed to examine the relationship of participating in community activities (CA) with cognitive impairment and depressive mood independent of mobility disorder (MD) among older Japanese people. METHODS: Elderly residents in institutions or those requiring long-term care insurance services were excluded; questionnaires were mailed to 5401 older adults in 2013. The response rate was 94.3% (n=5094). We used multiple imputation to manage missing data...
December 29, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28067188/does-the-geriatric-depression-scale-have-utility-for-measuring-depression-severity
#10
Hussain Syed, Gregory Swanwick
The prevalence of major depression ranges from 1% to 16% among elderly living in private households or in institutions, and in similar settings "patients" with clinically relevant depressive symptoms vary between 7.2% and 49% (Djernes, 2006). Community studies looking at point prevalence of depression in older people suggest rates between 10% and 20% depending on cultural situations (Rodda et al., 2011).
January 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28063399/sleep-quality-among-elderly-high-altitude-dwellers-in-ladakh
#11
Ryota Sakamoto, Kiyohito Okumiya, Tsering Norboo, Norboo Tsering, Takayoshi Yamaguchi, Mitsuhiro Nose, Shinya Takeda, Toshihiro Tsukihara, Motonao Ishikawa, Shun Nakajima, Taizo Wada, Michiko Fujisawa, Hissei Imai, Yasuko Ishimoto, Yumi Kimura, Eriko Fukutomi, Wenling Chen, Kuniaki Otsuka, Kozo Matsubayashi
It has been already known that people who temporarily stay at high altitude may develop insomnia as a symptom of acute mountain sickness. However, much less is known about people living at high altitude. The aim of this study was to determine the effect of high altitude environment on sleep quality for the elderly who have been living at high altitude for their whole lives. A cross-sectional study was conducted in Domkhar valley at altitudes of 2800-4200m, Ladakh. Sleep quality was assessed using Insomnia Severity Index (ISI)...
December 29, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28062982/psychiatric-comorbidities-among-breast-cancer-survivors-in-south-korea-a-nationwide-population-based-study
#12
Jaesung Heo, Mison Chun, Young-Taek Oh, O Kyu Noh, Logyoung Kim
PURPOSE: The aim of this study was to analyze the prevalence of mental disorders in breast cancer survivors using claims data from the Health Insurance Review and Assessment Service in South Korea. We also analyzed patterns of mental disorders with respect to the time of diagnosis and age. MATERIALS AND METHODS: We confirmed mental disorders in a nationwide cohort of 87,843 people who were diagnosed with invasive breast cancer and underwent surgery between January 1, 2010 and December 31, 2014...
January 7, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28060527/moderating-effect-of-intrinsic-religiosity-on-the-relationship-between-depression-and-cognitive-function-among-community-dwelling-older-adults
#13
Hui Foh Foong, Tengku Aizan Hamid, Rahimah Ibrahim, Sharifah Azizah Haron
OBJECTIVES: Research has found that depression in later life is associated with cognitive impairment. Thus, the mechanism to reduce the effect of depression on cognitive function is warranted. In this paper, we intend to examine whether intrinsic religiosity mediates the association between depression and cognitive function. METHOD: The study included 2322 nationally representative community-dwelling elderly in Malaysia, randomly selected through a multi-stage proportional cluster random sampling from Peninsular Malaysia...
January 6, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28059648/validation-of-effectiveness-of-keyhole-clipping-in-nonfrail-elderly-patients-with-unruptured-intracranial-aneurysms
#14
Kentaro Mori, Kojiro Wada, Naoki Otani, Arata Tomiyama, Terushige Toyooka, Kazuya Fujii, Kosuke Kumagai, Satoru Takeuchi, Satoshi Tomura, Takuji Yamamoto, Yasuaki Nakao, Hajime Arai
OBJECTIVE Advanced age is known to be associated with a poor prognosis after surgical clipping of unruptured intracranial aneurysms (UIAs). Keyhole clipping techniques have been introduced for less invasive treatment of UIAs. In this study, the authors compared the complications and clinical and radiological outcomes after keyhole clipping between nonfrail elderly patients (≥ 70 years) and nonelderly patients. METHODS Keyhole clipping (either supraorbital or pterional) was performed to treat 260 cases of relatively small (≤ 10 mm) anterior circulation UIAs...
January 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28056068/the-association-between-polypharmacy-and-dementia-a-nested-case-control-study-based-on-a-12-year-longitudinal-cohort-database-in-south-korea
#15
Hae-Young Park, Ji-Won Park, Hong Ji Song, Hyun Soon Sohn, Jin-Won Kwon
Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. The objective of this study was to determine the association between polypharmacy and dementia through multiple statistical approaches. We conducted a nested case-control study for newly diagnosed dementia cases using the South Korean National Health Insurance Service sample cohort database (2002-2013, n = 1,025,340). Interactions between polypharmacy (an average use of ≥5 prescription drugs daily) and comorbidities or potentially inappropriate medications (PIMs) were tested...
2017: PloS One
https://www.readbyqxmd.com/read/28054834/long-term-restrictions-in-participation-in-stroke-survivors-under-and-over-70-years-of-age
#16
Joris A de Graaf, Maria L van Mierlo, Marcel W M Post, Wilco P Achterberg, L Jaap Kappelle, Johanna M A Visser-Meily
PURPOSE: This study aims to (1) assess differences in participation restrictions between stroke survivors aged under and over 70 years and (2) identify predictors associated with favorable and unfavorable long-term participation in both age groups. METHODS: Prospective cohort study in which 326 patients were assessed at stroke onset, two months and one year after stroke. The Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) was used to measure participation restrictions one year after stroke...
January 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28053520/psychometric-properties-of-the-physical-activity-scale-for-the-elderly-in-chinese-patients-with-copd
#17
Yan-Xia Tao, Lan Wang, Xiao-Yan Dong, Hong Zheng, Ya-Shu Zheng, Xing-Yue Tang, Yue Zhao, Qing Zhang
BACKGROUND: For patients with COPD, physical activity (PA) is recommended as the core component of pulmonary rehabilitation, but there is lack of a validated questionnaire for assessing the PA effectively. AIM: To evaluate the reliability and validity of the Chinese version of Physical Activity Scale for the Elderly (PASE-C) in patients with COPD. METHODS: A cross-sectional study was conducted with 167 outpatients aged 60 years or older with COPD...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28052767/psychometric-properties-of-the-chinese-version-of-spiritual-index-of-well-being-in-elderly-taiwanese
#18
Li-Fen Wu, Shu-Hui Yang, Malcolm Koo
BACKGROUND: Spiritual well-being has become an increasingly important issue for the elderly people. The 12-item Spirituality Index of Well-Being (SIWB) is a well-validated instrument for assessing a patient's current spiritual state. However, the psychometric properties of the SIWB in the Chinese elderly populations are not known. Therefore, this study translated the SIWB into Chinese and evaluated its psychometric properties. METHODS: The English version of the SIWB was first translated into Chinese based on the Brislin's translation model...
January 4, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28049503/effects-of-a-mutual-recovery-intervention-on-mental-health-in-depressed-elderly-community-dwelling-adults-a-pilot-study
#19
Chao Wang, Yujie Hua, Hua Fu, Longfeng Cheng, Wen Qian, Junyang Liu, Paul Crawford, Junming Dai
BACKGROUND: The prevalence of depression in the elderly is growing worldwide, and the population aging in China makes depression a major health problem for the elderly adults and a tremendous burden to the society. Effective interventions should be determined to provide an approach solving the problem and improving the situation. This study examined the effectiveness of a mutual recovery program intervention on depressive symptom, sleep quality, and well-being in community-dwelling elderly adults with depressive symptom in Shanghai...
January 3, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28049443/performance-of-edmonton-frail-scale-on-frailty-assessment-its-association-with-multi-dimensional-geriatric-conditions-assessed-with-specific-screening-tools
#20
Simone Perna, Matthew D'Arcy Francis, Chiara Bologna, Francesca Moncaglieri, Antonella Riva, Paolo Morazzoni, Pietro Allegrini, Antonio Isu, Beatrice Vigo, Fabio Guerriero, Mariangela Rondanelli
BACKGROUND: The aim of this study was to evaluate the performance of Edmonton Frail Scale (EFS) on frailty assessment in association with multi-dimensional conditions assessed with specific screening tools and to explore the prevalence of frailty by gender. METHODS: We enrolled 366 hospitalised patients (women\men: 251\115), mean age 81.5 years. The EFS was given to the patients to evaluate their frailty. Then we collected data concerning cognitive status through Mini-Mental State Examination (MMSE), health status (evaluated with the number of diseases), functional independence (Barthel Index and Activities Daily Living; BI, ADL, IADL), use of drugs (counting of drugs taken every day), Mini Nutritional Assessment (MNA), Geriatric Depression Scale (GDS), Skeletal Muscle Index of sarcopenia (SMI), osteoporosis and functionality (Handgrip strength)...
January 4, 2017: BMC Geriatrics
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