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Bert Müller, Janina Tatsios, Jan Klonner, Daniel Pilger, Antonia M Joussen
PURPOSE: To evaluate the efficacy of navigated focal laser photocoagulation in patients with chronic central serous chorioretinopathy (CSCR) and active leakage on fluorescein angiography (FA). METHODS: Thirty-two eyes of 32 patients (age 48 ± 11, m/f = 24/8) with persistent or recurrent CSCR (> 3 months) who received navigated laser photocoagulation (Navilas®) of leaking point(s) between June 2013 and 2016 were included in this retrospective case series...
June 6, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
V A Shaimova, T B Shaimov, R B Shaimov, A Yu Galin, Zh A Goloshchapova, P K Ryzhkov, A V Fomin
PURPOSE: To develop methods for evaluating effectiveness of YAG-laser vitreolysis of vitreous floaters. MATERIAL AND METHODS: The study included 144 patients (173 eyes) who had underwent YAG-laser vitreolysis and were under observation from 01.09.16 to 31.01.18. The patients were 34 to 86 years old (mean age 62.7±10.2 years), 28 (19.4%) patients were male, 116 (80.6%) - female. All patients underwent standard and additional examination: ultrasonography (Accutome B-scan plus, U...
2018: Vestnik Oftalmologii
M A Mannan, M A Hossain, J Nasim, Y Sabina, F Navila, D Subir
Since its inception, the neonatal mechanical ventilator has been considered an essential tool for managing preterm neonates with Respiratory Distress Syndrome (RDS) and is still regarded as an integral component in the neonatal respiratory care continuum. Mechanical ventilation of newborn has been practiced for several years with several advances made in the way. This clinical intervention study was done to analyze immediate outcome of preterm neonates with RDS required mechanical ventilation and conducted on preterm neonates with RDS required mechanical ventilation from July 2014 to June 2015...
January 2018: Mymensingh Medical Journal: MMJ
Christianne Micallef, Navila T Chaudhry, Alison H Holmes, Susan Hopkins, Jonathan Benn, Bryony Dean Franklin
Background: Electronic prescribing (EP) and electronic hospital pharmacy (EHP) systems are increasingly common. A potential benefit is the extensive data in these systems that could be used to support antimicrobial stewardship, but there is little information on how such data are currently used to support the quality and safety of antimicrobial use. Objectives: To summarize the literature on secondary use of data (SuD) from EP and EHP systems to support quality and safety of antimicrobial use, to describe any barriers to secondary use and to make recommendations for future work in this field...
July 1, 2017: Journal of Antimicrobial Chemotherapy
N F Sharif, Z Korade, N A Porter, F E Harrison
Smith-Lemli-Opitz syndrome is an inherited monogenic disorder in which mutations to the 7-dehydrocholesterol (7-DHC) reductase (Dhcr7) gene lead to deficits in cholesterol synthesis. As a result, many patients suffer from gross physiological and neurological deficits. The purpose of this study was to identify a potential abnormal behavioral phenotype in a compound mutant mouse model for Smith-Lemli-Opitz disease (Dhcr7 Δ3 -5/ T93M ) to further validate the model and to provide potential targets for future therapeutic interventions...
July 2017: Genes, Brain, and Behavior
S Voegeli, J P Howell, P Marti, M K Schmid
Background The navigated laser photocoagulation system (NAVILAS®, OD-OS GmBH, Teltow, Germany) is a laser treatment device that provides navigated laser treatment of the retina based on a fundus image. The purpose of this study was to investigate the accuracy of laser treatment based on external optical coherence tomography (OCT) images - a new application of the device. Patients and Methods This retrospective case series evaluated the accuracy of laser spot placement in 7 eyes after using overlaid external OCT images for planning NAVILAS laser treatment...
April 2017: Klinische Monatsblätter Für Augenheilkunde
Umit Ubeyt Inan, Onur Polat, Sibel Inan, Safiye Yigit, Zeki Baysal
PURPOSE: To compare the pain responses of patients with proliferative diabetic retinopathy (PDR) undergoing panretinal photocoagulation (PRP) using either pattern scan laser (PASCAL) or navigated laser photocoagulation (NAVILAS). METHODS: Patients diagnosed with PDR were randomly assigned to undergo either PASCAL or NAVILAS photocoagulation treatment. PRP was performed using the multi-shot mode with a spot size of 200-400 µm and a pulse duration of 30 ms to obtain a white-grayish spot on the retina...
February 2016: Arquivos Brasileiros de Oftalmologia
Michael A Singer, Colin S Tan, Krishna R Surapaneni, Srinivas R Sadda
INTRODUCTION: Peripheral retinal ischemia not detectable by conventional fluorescein angiography has been proposed to be a driving force for rebound edema in retinal vein occlusions. In this report, we examine the treatment of peripheral retinal ischemia with targeted retinal photocoagulation (TRP) to manage a patient's rebound edema. METHODS: To assess the extent of peripheral nonperfusion, an Optos 200Tx device was used. To target the treatment to peripheral ischemia areas, a Navilas Panretinal Laser was used...
2015: Clinical Ophthalmology
Saeed T Alshahrani, Nicola G Ghazi
PURPOSE: To report the utility of navigated laser (NAVILAS) in the treatment of leaking areas in central serous chorioretinopathy and a feeder vessel in choroidal neovascular membrane. METHODS: Two patients with choroidal lesions were treated with NAVILAS. The first patient had central serous chorioretinopathy with visible leaking angiographic spots, and the second had choroidal neovascular membrane with a well-defined feeder vessel on angiography. Both patients underwent NAVILAS treatment...
2015: Retinal Cases & Brief Reports
Jay Chhablani, Padmaja Kumari Rani, Annie Mathai, Subhadra Jalali, Igor Kozak
BACKGROUND AND OBJECTIVE: To assess the efficacy of navigated laser (Navilas(®)) treatment for central serous chorioretinopathy. MATERIALS AND METHODS: Prospective study included 16 eyes of 15 subjects with nonresolving central serous chorioretinopathy. Fluorescein-angiography guided Navilas(®) treatment was performed. Pre- and posttreatment best-corrected visual acuity, pre- and posttreatment central macular thickness, number of leaks on fluorescein angiography, and various treatment parameters were analyzed...
2014: Clinical Ophthalmology
Alexandra E Hoeh, Stefanie Pollithy, Stefan Dithmar
PURPOSE: To evaluate the effect of patient-associated factors on the minimum laser power needed for a mild visible burn in focal laser treatments using the 532 nm Navilas laser system. METHODS: We conducted a monocentric prospective pilot study of 58 eyes of 40 patients with diabetic macular edema. The following parameters were analysed: axial length, refraction, iris pigmentation, lens status, lens grading and densitometry, retinal and choroidal thickness and focus setting during treatment...
June 2015: Graefe's Archive for Clinical and Experimental Ophthalmology
Jay Chhablani, Annie Mathai, Padmaja Rani, Vishali Gupta, J Fernando Arevalo, Igor Kozak
PURPOSE: To compare the laser spot quality between the conventional slit lamp pattern laser (PASCAL) and the navigated pattern laser (NAVILAS) for panretinal photocoagulation (PRP). METHODS: Prospective randomized interventional trial of 73 eyes (51 patients) with high-risk proliferative diabetic retinopathy. Eyes underwent PRP using 30-ms pulse duration with either PASCAL (16 eyes) or NAVILAS laser (21 eyes), or 100-ms pulse duration with either PASCAL (16 eyes) or NAVILAS laser (20 eyes)...
May 1, 2014: Investigative Ophthalmology & Visual Science
Jesse J Jung, Roberto Gallego-Pinazo1, Antonio Lleó-Pérez, Jonathan I Huz, Irene A Barbazetto
PURPOSE: To report one year outcomes of focal Navigated Retina Laser Therapy (NAVILAS) for diabetic macular edema (DME). METHODS: Retrospective cohort series of 7 diabetic patients treated with NAVILAS focal laser. Statistical analysis included descriptive and continuous variables (Best-corrected logMAR Visual Acuity and time-domain optical coherence tomography (OCT) parameters) which were compared using a non-parametric procedure, the Friedman tests for repeated measures...
2013: Open Ophthalmology Journal
M Kernt, M Ulbig, A Kampik, A S Neubauer
Navigated laser therapy introduces for the first time computerized assistance systems for retinal laser therapy. The Navilas system offers high precision and safety and provides additional benefits regarding standardization of planning, execution, documentation and quality assurance. The current focus of clinical application for navigated laser therapy besides laser treatment after retinal vein occlusion and panretinal laser photocoagulation in proliferative diabetic retinopathy (PDR) is diabetic macular edema...
August 2013: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
A J Starnawska, U Schneider, P W Hasler
INTRODUCTION: The aim of this study was to compare individual accuracy and speed of laser application using the Navilas laser system in patients with diabetic and vascular macular oedema. METHODS: The Navilas laser system was used by an experienced retina specialist and a relatively inexperienced ophthalmologist. Obtained results were retrospectively assessed with regard to precision and speed of laser application. RESULTS: Precision of laser therapy was quite similar, 88 % and 84 % for experienced and inexperienced operators, respectively...
December 2012: Klinische Monatsblätter Für Augenheilkunde
Michael D Ober, Marcus Kernt, Marco A Cortes, Igor Kozak
BACKGROUND: Navilas laser is a novel technology combining photocoagulation with imaging, including fluorescein angiographic (FA) images which are annotated and aligned to a live fundus view. We determine the time necessary for planning and treatment of macular edema utilizing the Navilas. METHODS: The screen recordings during treatments were retrospectively analyzed for treatment type, number of laser shots, the duration of planning (measured from the time the planning image was selected to time of marking the last planned treatment spot), and total time of laser application...
April 2013: Graefe's Archive for Clinical and Experimental Ophthalmology
M Kernt, R Cheuteu, R G Liegl, F Seidensticker, S Cserhati, C Hirneiss, C Haritoglou, A Kampik, M Ulbig, A S Neubauer
PURPOSE: The aim of this study was to investigate the accuracy of a navigated laser photocoagulator in clinically significant macular edema (CSME). METHODS: Focal laser treatment for diabetic macular edema (DME) in 36 patients was digitally planned on fundus images and performed with navigation using NAVILAS® (OD-OS, Teltow, Germany). Treatment intensity was controlled visually during treatment so the laser spots applied were barely directly visible after treatment...
July 2012: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Marcus Kernt, Raoul E Cheuteu, Sarah Cserhati, Florian Seidensticker, Raffael G Liegl, Julian Lang, Christos Haritoglou, Anselm Kampik, Michael W Ulbig, Aljoscha S Neubauer
AIM: To investigate treatment-related pain and the accuracy of navigated laser photocoagulation in the treatment of clinically significant macular edema. METHODS: Focal laser treatment of diabetic macular edema in 54 consecutive patients was digitally planned on fundus images and performed using the navigated laser photocoagulation system Navilas(®) (OD-OS GmbH, Teltow, Germany). Treatment-related pain was quantified on a visual analog scale directly after treatment and compared with a matched control group who received conventional laser treatment (n = 46)...
2012: Clinical Ophthalmology
Kakarla V Chalam, Ravi K Murthy, Vikram Brar, Ravi Radhakrishnan, Vijay Khetpal, Sandeep Grover
PURPOSE: To evaluate the procedural experience and complications of a novel integrated laser delivery system (NAVILAS(®); OD-OS Teltow, Germany) that combines automated laser delivery with color fundus photography, fluorescein angiography (FA), fundus autofluorescence (FAF) and infrared imaging with a frequency doubled YAG laser. MATERIALS AND METHODS: This prospective study evaluated surgical experience with the NAVILAS automated photocoagulation system for the treatment of patients with diabetic macular edema (DME)...
January 2012: Middle East African Journal of Ophthalmology
Igor Kozak, Jae Suk Kim, Stephen F Oster, Jay Chhablani, William R Freeman
PURPOSE: To evaluate clinical results after the use of a novel integrated imaging and laser device to perform focal retinal navigated laser photocoagulation in perifoveal abnormalities and retinovascular disease. METHODS: Interventional case series of 25 consecutive eyes with perifoveal and retinovascular diseases treated with a navigated laser photocoagulator Navilas (OD-OS, Berlin, Germany). We treated eyes with perifoveal telangiectasia (n = 3), central serous chorioretinopathy (n = 2), and diabetic macular edema with focal leakage (n = 20)...
May 2012: Retina
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