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https://www.readbyqxmd.com/read/29356452/a-gross-anatomy-flipped-classroom-effects-performance-retention-and-higher-level-thinking-in-lower-performing-students
#1
Leslie J Day
A flipped classroom is a growing pedagogy in higher education. Many research studies on the flipped classroom have focused on student outcomes, with the results being positive or inconclusive. A few studies have analyzed confounding variables, such as student's previous achievement, or the impact of a flipped classroom on long-term retention and knowledge transfer. In the present study, students in a Doctor of Physical Therapy program in a traditional style lecture of gross anatomy (n = 105) were compared to similar students in a flipped classroom (n = 112)...
January 22, 2018: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29356446/local-and-systemic-immune-responses-to-different-types-of-phytohemagglutinin-in-the-green-anole-lessons-for-field-ecoimmunologists
#2
Catherine Tylan, Tracy Langkilde
The phytohemagglutinin (PHA) skin test is commonly used by ecologists to assess cell-mediated immune function of wild animals. It can be performed quickly and easily in the field, involving injection of PHA and measurement of the resultant swelling. There are multiple formulations of PHA used in ecological studies, with potentially differing outcomes that could produce inconsistent results. We tested two common types of PHA in the green anole (Anolis carolinensis) to identify local and systemic immune responses underlying the resultant swelling at 6, 18, 24, and 48 hr post injection...
June 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356442/detrimental-interactions-of-neonicotinoid-pesticide-exposure-and-bumblebee-immunity
#3
Mitchell Andrew Czerwinski, Ben Michael Sadd
Pesticides are well known to have a number of ecological effects. However, it is only now becoming understood that sublethal exposures may have effects on nontarget insects of conservation concern through interactions with immunity, thus increasing detrimental impacts in the presence of pathogens. Pesticides and pathogens are suggested to have played a role in recent declines of several wild bee pollinators. Compromised immunity from exposure to widely used neonicotinoids has been demonstrated in honeybees, but further research on interactions between neonicotinoids and immunity in other important bees is lacking...
June 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356435/correlates-of-melanization-in-multiple-high-and-low-elevation-populations-of-the-lizard-sceloporus-occidentalis-behavior-hormones-and-parasites
#4
Ryan J Seddon, Diana K Hews
Hormones mediate the expression of suites of correlated traits and hence may act either to facilitate or constrain adaptive evolution. Selection on one trait within a hormone-mediated suite of traits may lead to a change in the strength of the hormone signal, causing changes in correlated traits. Growing evidence suggests that melanization, which is in part regulated by hormonal signals, is tightly linked to other traits, such as aggression and stress physiology. Here, we examine six populations of Sceloporus occidentalis lizards differing in degree of melanization (three dark higher-elevation populations and three less-melanized lower-elevation populations) to investigate potential correlations between behavior, hormones, and parasites...
October 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356409/scalable-synthesis-of-triple-core-shell-nanostructures-of-tio2-mno2-c-for-high-performance-supercapacitors-using-structure-guided-combustion-waves
#5
Dongjoon Shin, Jungho Shin, Taehan Yeo, Hayoung Hwang, Seonghyun Park, Wonjoon Choi
Core-shell nanostructures of metal oxides and carbon-based materials have emerged as outstanding electrode materials for supercapacitors and batteries. However, their synthesis requires complex procedures that incur high costs and long processing times. Herein, a new route is proposed for synthesizing triple-core-shell nanoparticles of TiO2 @MnO2 @C using structure-guided combustion waves (SGCWs), which originate from incomplete combustion inside chemical-fuel-wrapped nanostructures, and their application in supercapacitor electrodes...
January 22, 2018: Small
https://www.readbyqxmd.com/read/29356396/a-multi-locus-association-analysis-method-integrating-phenotype-and-expression-data-reveals-multiple-novel-associations-to-flowering-time-variation-in-wild-collected-arabidopsis-thaliana
#6
Yanjun Zan, Örjan Carlborg
The adaptation to a new habitat often results in a confounding between genome-wide genotype and beneficial alleles. When the confounding is strong, or the allelic effects weak, it is a major statistical challenge to detect the adaptive polymorphisms. We describe a novel approach to dissect polygenic traits in natural populations. First, candidate adaptive loci are identified by screening for loci directly associated with the adaptive trait or the expression of genes known to affect it. Then, a multi-locus genetic architecture is inferred using a backward elimination association analysis across all candidate loci with an adaptive false discovery rate based threshold...
January 22, 2018: Molecular Ecology Resources
https://www.readbyqxmd.com/read/29356384/demographic-and-temporal-variations-in-immunity-and-condition-of-polar-bears-ursus-maritimus-from-the-southern-beaufort-sea
#7
Lorin A Neuman-Lee, Patricia A Terletzky, Todd C Atwood, Eric M Gese, Geoffrey D Smith, Sydney Greenfield, John Pettit, Susannah S French
Assessing the health and condition of animals in their natural environment can be problematic. Many physiological metrics, including immunity, are highly influenced by specific context and recent events to which researchers may be unaware. Thus, using a multifaceted physiological approach and a context-specific analysis encompassing multiple time scales can be highly informative. Ecoimmunological tools in particular can provide important indications to the health of animals in the wild. We collected blood and hair samples from free-ranging polar bears (Ursus maritimus) in the southern Beaufort Sea and examined the influence of sex, age, and reproductive status on metrics of immunity, stress, and body condition during 2013-2015...
June 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356375/molecular-characterization-and-tissue-expression-profiles-of-prepro-vasoactive-intestinal-peptide-in-the-chinese-alligator-alligator-sinensis-during-the-active-and-hibernating-periods
#8
Sheng-Zhou Zhang, Ting Meng, Xue Zhu, Huan Wang, Yong-Kang Zhou, Xiao-Bing Wu
The Chinese alligator (Alligator sinensis), a freshwater crocodilian endemic to China, is one of the most endangered crocodilian species; up to this date, very little is known about the endocrine regulation of its metabolic activities during different physiological states. In this study, we characterized the structure of the prepro-vasoactive intestinal peptide in Chinese alligator (prepro-caVIP) for the first time and examined its expression profiles in various tissues during the active and hibernating periods...
February 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29356363/high-performance-photovoltaic-detector-based-on-mote2-mos2-van-der-waals-heterostructure
#9
Yan Chen, Xudong Wang, Guangjian Wu, Zhen Wang, Hehai Fang, Tie Lin, Shuo Sun, Hong Shen, Weida Hu, Jianlu Wang, Jinglan Sun, Xiangjian Meng, Junhao Chu
Van der Waals heterostructures based on 2D layered materials have received wide attention for their multiple applications in optoelectronic devices, such as solar cells, light-emitting devices, and photodiodes. In this work, high-performance photovoltaic photodetectors based on MoTe2 /MoS2 vertical heterojunctions are demonstrated by exfoliating-restacking approach. The fundamental electric properties and band structures of the junction are revealed and analyzed. It is shown that this kind of photodetectors can operate under zero bias with high on/off ratio (>105 ) and ultralow dark current (≈3 pA)...
January 22, 2018: Small
https://www.readbyqxmd.com/read/29356356/phase-angle-measured-by-electrical-bioimpedance-and-global-cardiovascular-risk-in-older-adults
#10
Maria An Saad, Antonio Jl Jorge, Wolney de Andrade Martins, Gilberto P Cardoso, Marcia Ms Dos Santos, Maria Lg Rosa, Giovanna Ab Lima, Rafaela Q de Moraes, Rubens A da Cruz Filho
AIM: Population aging is a worldwide phenomenon associated with physiological and metabolic changes that contribute to the increased prevalence of risk factors for cardiovascular disease. The phase angle (PA) is a variable calculated by bioelectrical impedance analysis, interpreted as a direct measure of cell stability. The objective of the present study was to investigate the correlation of PA with the anthropometric measures, metabolic profile and the cardiovascular risk estimated by the Global Cardiovascular Risk Score in the elderly population...
January 22, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29356342/the-human-eye-proteome-project-updates-on-an-emerging-proteome
#11
REVIEW
Meleha T Ahmad, Pingbo Zhang, Craig Dufresne, Luigi Ferrucci, Richard D Semba
The human eye is a complex organ consisting of multiple compartments with unique and specialized properties that reflect their varied functions. Although there have been advancements in ocular imaging and therapeutics over the past decade, the pathogenesis of many common eye diseases remains poorly understood. Proteomics is an invaluable tool to gain insight into pathogenesis, diagnosis, and treatment of eye diseases. By 2013, when the Human Eye Proteome Project (also known as the EyeOme) was founded, there were 4,842 non-redundant proteins identified in the human eye...
January 22, 2018: Proteomics
https://www.readbyqxmd.com/read/29356278/antiplatelet-drug-selection-in-pci-to-vein-grafts-in-patients-with-acute-coronary-syndrome-and-adverse-clinical-outcomes-insights-from-the-british-cardiovascular-intervention-society-database
#12
Alex Sirker, Chun Shing Kwok, Evangelos Kontopantelis, Tom Johnson, Philip Freeman, Mark A de Belder, Peter Ludman, Azfar Zaman, Mamas A Mamas
OBJECTIVE: This study aims to evaluate outcomes associated with different P2Y12 agents in Saphenous Vein graft (SVG) percutaneous coronary intervention (PCI). BACKGROUND: SVG PCI is associated with greater risks of ischemic complications, compared with native coronary PCI. Outcomes associated with the use of potent P2Y12 blocking drugs, Prasugrel and Ticagrelor, in SVG PCI are unknown. METHODS: Patients included in the study underwent SVG PCI in the United Kingdom between 2007 and 2014 for acute coronary syndrome and were grouped by P2Y12 antiplatelet use...
January 22, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29356252/white-matter-integrity-disruptions-correlate-with-cognitive-impairments-in-asthma
#13
Rongrong Bian, Yuqun Zhang, Yuan Yang, Yingying Yin, Xiaoxin Zhao, Huanxin Chen, Yonggui Yuan
BACKGROUND: Cognitive impairments are common in asthma, which is a serious global health problem characterized by chronic airway inflammation. However, the underlying neuromechanism is still unclear. PURPOSE/HYPOTHESIS: To investigate the neuromechanism underlying cognitive impairments of asthma. We hypothesized that asthma patients exhibit altered white matter (WM) microstructures, which may contribute to their cognitive impairments. STUDY TYPE: Case-control study...
January 21, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29356229/brain-tumor-segmentation-in-multi-spectral-mri-using-convolutional-neural-networks-cnn
#14
Sajid Iqbal, M Usman Ghani, Tanzila Saba, Amjad Rehman
A tumor could be found in any area of the brain and could be of any size, shape, and contrast. There may exist multiple tumors of different types in a human brain at the same time. Accurate tumor area segmentation is considered primary step for treatment of brain tumors. Deep Learning is a set of promising techniques that could provide better results as compared to nondeep learning techniques for segmenting timorous part inside a brain. This article presents a deep convolutional neural network (CNN) to segment brain tumors in MRIs...
January 22, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29356225/combining-synthetic-controls-and-interrupted-time-series-analysis-to-improve-causal-inference-in-program-evaluation
#15
Ariel Linden
RATIONALE, AIMS AND OBJECTIVES: Interrupted time series analysis (ITSA) is an evaluation methodology in which a single treatment unit's outcome is studied over time and the intervention is expected to "interrupt" the level and/or trend of the outcome. The internal validity is strengthened considerably when the treated unit is contrasted with a comparable control group. In this paper, we introduce a robust evaluation framework that combines the synthetic controls method (SYNTH) to generate a comparable control group and ITSA regression to assess covariate balance and estimate treatment effects...
January 22, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29356206/survey-of-diagnostic-and-treatment-practices-for-multiple-sclerosis-in-europe-part-2-progressive-ms-paediatric-ms-pregnancy-and-general-management
#16
Oscar Fernández, Mario Delvecchio, Gilles Edan, Sten Fredrikson, Gavin Giovannoni, Hans-Peter Hartung, Eva Havrdova, Ludwig Kappos, Carlo Pozzilli, Per Soelberg Soerensen, Björn Tackenberg, Patrick Vermersch, Giancarlo Comi
BACKGROUND AND PURPOSE: The European Charcot Foundation supported development of a set of surveys to understand current practice patterns for diagnosis and management of multiple sclerosis (MS) in Europe. Part 2 of the report summarises survey results related to secondary progressive MS (SPMS), primary progressive MS (PPMS), pregnancy, paediatric MS and overall patient management. METHODS: A steering committee of MS neurologists developed case- and practice-based questions for two sequential surveys distributed to MS neurologists throughout Europe...
January 21, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29356186/the-blomia-tropicalis-allergen-blo-t-7-stimulates-innate-immune-signaling-pathways-through-tlr2
#17
Tewarit Soongrung, Karntichar Mongkorntanyatipa, Termsri Peepim, Arun Buaklin, Maxime Le Mignon, Nat Malainual, Emmanuel Nony, Alain Jacquet
BACKGROUND: Although the house dust mite species Blomia tropicalis is a leading cause of allergic diseases in tropical and subtropical regions, the identification and characterization of the allergenic proteins remains incomplete. OBJECTIVE: We aimed to characterize a recombinant form of Blo t 7 (rBlo t 7) in terms of IgE reactivity, lipid binding activity and ability to stimulate innate immunity. METHODS: The mature Blo t 7 cDNA was cloned by PCR methods for the expression of a secreted form of the allergen in P...
January 22, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29356179/neutrophil-to-lymphocyte-ratio-in-head-and-neck-cancer-prognosis-a-systematic-review-and-meta-analysis
#18
Marco A Mascarella, Erin Mannard, Sabrina Daniela Silva Wurzba, Anthony Zeitouni
BACKGROUND: Hematologic markers, such as the neutrophil-to-lymphocyte ratio (NLR), characterize the inflammatory response to cancer and are associated with poorer survival in various malignancies. We evaluate the effect of pretreatment NLR on overall survival (OS) in patients with head and neck squamous cell carcinoma (HNSCC). METHODS: Using multiple databases, a systematic search for articles evaluating the effect of NLR on OS in patients with HNSCC was performed...
January 22, 2018: Head & Neck
https://www.readbyqxmd.com/read/29356175/radioprotective-effects-of-dammarane-sapogenins-against-60-co-induced-myelosuppression-in-mice
#19
Liming Dong, Yanyan Yang, Yan Lu, Cong Lu, Jingwei Lv, Ning Jiang, Qiuxia Xu, Yue Gao, Qi Chang, Xinmin Liu
Radiotherapy frequently induces failure of hematopoietic system and leads to myelosuppression. The objective of this study was to investigate the protective effect of dammarane sapogenins (DS), the hydrolysed product of the constituent ginsenosides of Panax ginseng, which are produced by gut metabolism, on radiation-induced hematopoietic injury. Mice were exposed to 3.5 Gy 60 Co γ-rays of total body radiation at a dose rate of 1.60 Gy per minute and treated with DS or granulocyte colony-stimulating factor immediately after radiation...
January 22, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29356135/neurogenic-bladder-in-progressive-supranuclear-palsy-a-comparison-with-parkinson-s-disease-and-multiple-system-atrophy
#20
Kyeong Joon Kim, Seong Jin Jeong, Jong-Min Kim
AIMS: Progressive supranuclear palsy (PSP) can present urinary symptoms, similar to other parkinsonian disorders. We investigated the urodynamic parameters of PSP and compared them with those of idiopathic Parkinson's disease (IPD) and multiple system atrophy (MSA) METHODS: We retrospectively analyzed the urodynamic data in patients diagnosed with parkinsonian disorders (PSP, IPD, and MSA) presenting urinary symptoms. Clinical data, including onset age, duration, and severity, as well as treatment status of parkinsonian disorders and urinary symptoms were collected...
January 22, 2018: Neurourology and Urodynamics
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