keyword
https://read.qxmd.com/read/38526705/squamous-cell-carcinoma-of-the-anus-successfully-treated-with-multidisciplinary-therapy-for-metachronous-metastatic-and-local-recurrences-after-dcf-chemotherapy-a-case-report
#1
JOURNAL ARTICLE
Ryozan Naito, Takuya Shiraishi, Nobuhiro Hosoi, Takayoshi Watanabe, Ikuma Shioi, Yuta Shibasaki, Nobuhiro Nakazawa, Katsuya Osone, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Hiroomi Ogawa, Makoto Sohda, Ken Shirabe, Hiroshi Saeki
BACKGROUND: Docetaxel, cisplatin, and 5-fluorouracil (DCF) chemotherapy is reportedly an effective treatment strategy for squamous cell carcinoma of the anus (SCCA). However, studies regarding its use in Japanese patients remain scarce. CASE PRESENTATION: Here, we present the case of an 82-year-old woman with SCCA, cStage IIIB. Chemoradiotherapy was initiated after colostomy of the anorectal mass; however, para-aortic lymph node recurrence was observed 3 months after treatment completion...
March 25, 2024: Surgical Case Reports
https://read.qxmd.com/read/38515573/high-grade-serous-papillary-ovarian-carcinoma-combined-with-nonkeratinizing-squamous-cell-carcinoma-of-the-cervix-a-case-report
#2
Maoyuan Wu, Wenwen Zhang, Lianli He, Ye Zhu, Xiaoling Jiang, Lixia Zhang, Xiwei Yuan, Tingchao Li
Multiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral salpingo-oophorectomy + pelvic lymph node dissection + para-aortic lymphadenectomy + appendectomy + omentectomy + metastasectomy under general anesthesia. The patient experienced complete remission after six courses of postoperative chemotherapy with a standard Taxol and Carboplatin regimen...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38487605/a-review-of-laparoscopic-para-aortic-lymphadenectomy-for-early-stage-endometrial-cancer-extraperitoneal-approach-may-have-the-advantage-over-intraperitoneal-approach
#3
REVIEW
Kazuaki Imai, Junko Hirooka-Nakama, Yuichiro Hotta, Hiroyuki Shigeta
The importance of lymphadenectomy, including para-aortic nodes, for the accurate staging of endometrial cancer, is well established. Although the therapeutic role of lymph node resection in endometrial cancer is still under debate, some studies support its usefulness for survival benefit. To predict the necessity of lymphadenectomy, several preoperative scoring systems have been proposed as being effective. For endometrial cancer, there is a trend towards minimally invasive surgery, including para-aortic lymphadenectomy...
2024: Gynecology and Minimally Invasive Therapy
https://read.qxmd.com/read/38411760/laparoscopic-dissection-of-lymph-node-station-16-why-and-how
#4
JOURNAL ARTICLE
William Kawahara, Eduardo A Vega, Omid Salehi, Sebastian Mellado, Oscar Salirrosas, Richard Freeman, Elena Panettieri, Claudius Conrad
BACKGROUND: Dissection of para-aortic lymph nodes (Station 16) provides an important prognosticator for patients with gastrointestinal, colorectal, and hepatobiliary cancers.1-4 For example, a positive Station 16 lymph node has been shown to lead to 2-year survival of 3% in patients with pancreas adenocarcinoma, akin to stage IV disease.5,6 Thereby, Station 16 involvement can help with the risk/benefit stratification of the decision to move forward with radical surgery.7-9 Furthermore, it has been shown for gallbladder cancer that involvement of Station 16 cannot necessarily be predicted from the dissection of the hepatoduodenal ligament lymph nodes only...
February 27, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38351794/laparoscopic-para-aortic-lymphadenectomy-for-metastatic-colon-cancer-in-a-patient-with-left-sided-inferior-vena-cava-a-case-report
#5
JOURNAL ARTICLE
Efstathios Kotidis, Elissavet Anestiadou, Aikaterini Karamitsou, Georgios Gemousakakis, Orestis Ioannidis, Stefanos Bitsianis, Savvas Symeonidis, Nikolaos Ouzounidis, Odysseas Lomvardeas, Stamatios Aggelopoulos
Transposition of inferior vena cava, or, left-sided inferior vena cava (LS-IVC) is a rare clinical entity, in which the inferior vena cava ascends along the left side of the abdominal aorta. Literature contains mainly clinical case reports. Although it is usually not associated with clinical symptomatology, this anomaly should be detected during preoperative planning to avoid iatrogenic injuries intraoperatively. We present a case of left-sided inferior vena cava encountered during laparoscopic lymphadenectomy in a 45-year-old man with previous laparoscopic hemicolectomy due to colon adenocarcinoma...
December 31, 2023: Folia Medica
https://read.qxmd.com/read/38303328/-brain-metastasis-following-conversion-surgery-for-sigmoid-colon-cancer-a-case-report
#6
JOURNAL ARTICLE
Takashi Takenoya, Shinji Murai, Hiroaki Ando, Fumitaka Nakayama, Yusuke Asada, Ippei Oto, Takahisa Yoshikawa, Tetsuya Nakamura, Nobushige Yabe, Koji Osumi, Noriaki Kameyama
A 64-year-old man was diagnosed with KRAS-mutant type sigmoid colon cancer with metastasis in the lung, liver, left adrenal gland, and para-aortic lymph node(T3N1M1b, Stage ⅣB[Union for International Cancer Control 8th edition]). Laparoscopic transverse colostomy was performed to treat colonic obstruction. Subsequently, a combination regimen of capecitabine plus oxaliplatin plus bevacizumab was administered. After 5 courses of chemotherapy, the S8 liver tumor disappeared completely. Sigmoidectomy, para-aortic lymph node dissection, and left adrenal gland resection were performed...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38303300/-a-case-of-preoperative-chemotherapy-for-advanced-gastric-cancer-laparoscopic-total-gastrectomy-pancreaticoduodenectomy-and-para-aortic-lymph-node-dissection
#7
JOURNAL ARTICLE
Kenta Fukuda, Kazuki Odagiri, Yoshitomo Yanagimoto, Masafumi Yamashita, Hiroshi Takeyama, Yozo Suzuki, Masakazu Ikenaga, Tomono Kawase, Junzo Shimizu, Hiroshi Imamura, Keizo Dono
Bulky N+ gastric cancer has a poor prognosis. The results of JCOG0405 showed the efficacy of neoadjuvant chemotherapy with S-1 plus cisplatin combination therapy for Bulky N+ gastric cancer. JLSSG0901 demonstrated the safety and efficacy of laparoscopic surgery for advanced gastric cancer. But the safety of laparoscopic surgery for locally advanced and extensive nodal metastasis cancer(T4b, para-aortic lymph node metastasis)is not apparent. After DOS therapy, we performed total laparoscopic gastrectomy, DP(distal pancreatectomy), D2+ #16a2/b1 lat, and Roux-en-Y reconstruction, and histopathological results showed that the aortic lymph node metastasis disappeared...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38303179/-laparoscopic-splenectomy-for-metachronous-splenic-metastasis-of-fallopian-tube-cancer-with-synchronous-rectal-metastasis-a-case-report
#8
JOURNAL ARTICLE
Tadashi Tsukamoto, Takaaki Hori, Chihoko Nobori, Gen Tsujio, Tomohiro Kunimoto, Ryoji Kaizaki, Satoshi Takatsuka, Shinichi Nakata, Hiroko Fukushima
A 59-year-old woman underwent simple abdominal total hysterectomy with bilateral salpingo-oophorectomy, partial omentectomy, and extirpation of intrapelvic disseminated nodules for right fallopian tube cancer with rectal metastasis and peritoneal dissemination as primary debulking surgery(PDS). The histopathological diagnosis was high grade serous carcinoma( HGSC)of the right fallopian tube. After adjuvant chemotherapy with 4 courses of paclitaxel-carboplatin(TC), low anterior resection of the rectum for rectal metastasis and pelvic and para-aortic lymph node dissection were performed as interval debulking surgery(IDS)...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38303168/-conversion-surgery-performed-after-sox-plus-nivolumab-therapy-for-advanced-gastric-cancer-with-para-aortic-lymph-node-metastasis
#9
JOURNAL ARTICLE
Tadahiro Okuda, Kazuki Odagiri, Yoshitomo Yanagimoto, Masafumi Yamashita, Hiroshi Takeyama, Yozo Suzuki, Masakazu Ikenaga, Tomono Kawase, Junzo Shimizu, Hiroshi Imamura, Keizo Dono
The patient was a 78-year-old woman. She presented with anemia and a positive fecal occult blood test. Endoscopic findings revealed type 3 advanced gastric cancer. As it had metastasized to the para-aortic lymph node(PALN: No. 16a2 lat), it was diagnosed as gastric cancer at cardia cT4aN1(No.1)M1(No.16a2 lat), cStage Ⅳ. She was administered S-1, oxaliplatin, and nivolumab(SOX plus Nivo)therapy as a first-line treatment. SOX plus Nivo resulted in a remarkable reduction of the lymph nodes, which were PR...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38262905/-advancements-in-research-on-para-aortic-lymph-node-dissection-in-colorectal-cancer
#10
JOURNAL ARTICLE
P Chi, Y W Sun
Para-aortic lymph node metastasis from colorectal cancer is relatively rare. Recent studies have shown that curative para-aortic lymph node dissection can lead to similar prognoses as stage III colorectal cancer for selected patients. However, there are still many unresolved debates regarding the appropriate surgical indications, extent of lymph node dissection, and treatment principles for colorectal cancer patients with para-aortic lymph node metastasis. With the continuous improvement of laparoscopic colorectal surgery techniques, the previously complex and high-risk procedure of para-aortic lymph node dissection has now become a safe and feasible approach...
January 25, 2024: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38247071/-a-case-of-late-recurrent-msi-high-stage%C3%A2-b-gastric-cancer-after-surgery
#11
JOURNAL ARTICLE
Takahiro Ikeshita, Takayuki Kuga, Masatoshi Shigeta, Yuka Yano
Late recurrence of stage ⅠB gastric cancer with high microsatellite instability(MSI-high)is rare. Here, we report a case of MSI-high StageⅠB gastric cancer recurring more than 5 years after surgery. A 78-yaer-old man was admitted to our hospital for gastric cancer surgery. Laparoscopic distal gastrectomy was performed. Histologic examination revealed a T2(MP) N0M0, HER2-negative, StageⅠB gastric tubular adenocarcinoma. Postoperatively, the patient received chemotherapy with S-1 for 1 year...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38136438/oncologic-outcome-of-robotic-assisted-and-laparoscopic-sentinel-node-biopsy-in-endometrial-cancer
#12
JOURNAL ARTICLE
Atanas Ignatov, József Mészáros, Stylianos Ivros, Paolo Gennari, Tanja Ignatov
BACKGROUND: Recently, sentinel lymph node biopsy (SLNB) has been introduced in the surgical staging of endometrial cancer as an alternative to systematic lymph node dissection (LND). However, the survival impact of SLNB is not yet well characterised. METHODS: We performed a retrospective study of 419 patients with endometrial cancer treated with SLNB alone or with pelvic and para-aortic LND. For SLNB mapping, indocyanine green was used. RESULTS: Median follow-up was 66 months...
December 18, 2023: Cancers
https://read.qxmd.com/read/38032383/comparison-of-the-diagnostic-value-of-68-%C3%A2-ga-ga-fapi-04-pet-mr-and-18-f-fdg-pet-ct-in-patients-with-t-stage%C3%A2-%C3%A2-%C3%A2-2a2-uterine-cervical-cancer-a-prospective-study
#13
JOURNAL ARTICLE
You Lyu, Xiaoyue Chen, Hua Liu, Yun Xi, Weiwei Feng, Biao Li
PURPOSE: To compare the diagnostic value of [68  Ga]Ga-FAPI-04 PET/MR and [18 F]FDG PET/CT in patients with T stage ≤ 2a2 uterine cervical cancer patients. METHODS: Patients pathologically diagnosed with cervical cancer and with a T stage ≤ T2a2 were prospectively enrolled. All patients underwent whole-body [68  Ga]Ga-FAPI-04 PET/MR and [18 F]FDG PET/CT within 2 weeks, and surgical treatment was performed within 10 days after PET...
November 30, 2023: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37994496/laparoscopic-salvage-surgery-for-infrarenal-para-aortic-lymph-node-recurrence-of-rectal-cancer
#14
JOURNAL ARTICLE
Dong-Hee Na, An Na Seo, Soo Yeun Park
No abstract text is available yet for this article.
November 16, 2023: Diseases of the Colon and Rectum
https://read.qxmd.com/read/37944943/robot-assisted-retroperitoneal-lymph-node-dissection-initial-experience-in-japan
#15
Kiyoshi Takahara, Tomonari Motonaga, Jin Okumura, Shinji Yamakawa, Kota Yagi, Wataru Nakamura, Masanobu Saruta, Takuhisa Nukaya, Masashi Takenaka, Kenji Zennami, Manabu Ichino, Hitomi Sasaki, Makoto Sumitomo, Ryoichi Shiroki
For patients with testicular tumors who need the surgical management, open retroperitoneal lymph node dissection (O-RPLND) is considered the gold standard treatment. However, recently, robot-assisted RPLND (R-RPLND) has gained popularity as a minimally invasive therapy alternative to O-RPLND and laparoscopic RPLND. Here, we report the case of a 32-year-old man presenting with a left testicular teratoma with several enlarged left para-aortic lymph nodes. After the orchiectomy, the patient underwent R-RPLND with an operation time of 279 min, console time of 189 min, bleeding volume of 59 mL, and no significant complications, resulting in a successful outcome...
January 2024: Asian Journal of Endoscopic Surgery
https://read.qxmd.com/read/37859537/the-fluorescence-imaging-for-laparoscopic-and-laparotomic-endometrial-sentinel-lymph-node-biopsy-filles-trial-siriraj-gynecologic-sentinel-node-of-endometrial-cancer-sign-en-study
#16
JOURNAL ARTICLE
Khemanat Khemworapong, Atthapon Jaishuen, Pisutt Srichaikul, Perapong Inthasorn, Boonlert Viriyapak, Vuthinun Achariyapota, Nida Jareemit, Malee Warnnissorn, Suchanan Hanamornroongruang, Jumnanja Sukmee
BACKGROUND AND OBJECTIVES: The objective of this study is to establish the detection rate of sentinel lymph node (SLN) biopsies and to determine the sensitivity and false-negative rate of SLN biopsies compared with those of systematic pelvic and para-aortic lymphadenectomies in endometrial cancer. METHODS: This prospective cohort study enrolled patients with endometrial cancer who were scheduled for surgical staging. Patients with a history of chemotherapy or radiotherapy, an abnormal liver function test, or an allergy to indocyanine green (ICG) were excluded...
October 19, 2023: Journal of Surgical Oncology
https://read.qxmd.com/read/37766911/ureter-injury-in-laparoscopic-para-aortic-lymphadenectomy-for-endometrial-cancer-by-the-transperitoneal-approach
#17
Hiroharu Kobayashi, Misa Kobayashi, Yoshihiro Takaki, Yuki Kondo, Yuri Hamada, Haruhiko Shimizu, Yumi Shimizu, Masaru Nagashima, Hiroshi Adachi
The patient was 66 years old, had three pregnancies and two deliveries, and was menopausal at the age of 51. She had irregular bleeding and was found to have a chicken-egg-sized uterus and a thickened endometrium (23 mm). She underwent laparoscopic surgery for uterine endometrial cancer (endometrioid carcinoma G1, stage IB). Laparoscopic simple hysterectomy, bilateral adnexectomy, pelvic lymph node dissection, para-aortic lymph node dissection, and partial omentectomy were performed using the transperitoneal approach (TPA)...
2023: Case Reports in Obstetrics and Gynecology
https://read.qxmd.com/read/37667757/evans-syndrome-during-pembrolizumab-therapy-for-upper-urinary-tract-cancer
#18
Shota Kakita, Tomohiro Matsuo, Masaharu Ohki, Ayaka Tsuchiyama, Takuji Yasuda, Hiromi Nakanishi, Kensuke Mitsunari, Kojiro Ohba, Ryoichi Imamura
INTRODUCTION: Immune checkpoint inhibitors are available for the treatment of advanced urothelial carcinoma; however, serious adverse events occasionally occur. Here, we report a rare case of Evans syndrome attributed to the use of an immune checkpoint inhibitor. CASE PRESENTATION: A 56-year-old man was diagnosed with left renal pelvic cancer and underwent left laparoscopic radical nephroureterectomy. Eight months postoperatively, computed tomography revealed para-aortic lymph node metastasis...
September 2023: IJU case reports
https://read.qxmd.com/read/37597853/primary-debulking-surgery-for-advanced-epithelial-ovarian-cancer-with-isolated-enlarged-para-aortic-lymph-node-by-robotic-transumbilical-single-port-approach
#19
JOURNAL ARTICLE
Yu Chen, Ying Zheng, Fan Yang
No abstract text is available yet for this article.
August 18, 2023: International Journal of Gynecological Cancer
https://read.qxmd.com/read/37418794/secondary-cytoreductive-surgery-in-recurrent-clear-cell-carcinoma-of-the-endometrium-a-case-report
#20
Connie Cheng, Nicole Jenkins, Noelle Aikman, Karim ElSahwi
INTRODUCTION & IMPORTANCE: Endometrial cancer with high-risk histology is associated with a majority of recurrences and death. However, unlike other cancers, such as ovarian, there is a paucity of research demonstrating the benefits of secondary cytoreduction. In this case report we aim to aid in identifying individuals who may be ideal candidates for secondary cytoreduction surgery after minimally invasive hysterectomy and staging by a gynecologic oncologist at an academic institution and diagnosed with clear cell endometrial cancer...
June 16, 2023: International Journal of Surgery Case Reports
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