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https://www.readbyqxmd.com/read/27565821/ac-electrokinetic-drug-delivery-in-dentistry-using-an-interdigitated-electrode-assembly-powered-by-inductive-coupling
#1
Chris S Ivanoff, Jie Jayne Wu, Hadi Mirzajani, Cheng Cheng, Quan Yuan, Stepan Kevorkyan, Radostina Gaydarova, Desislava Tomlekova
AC electrokinetics (ACEK) has been shown to deliver certain drugs into human teeth more effectively than diffusion. However, using electrical wires to power intraoral ACEK devices poses risks to patients. The study demonstrates a novel interdigitated electrode arrays (IDE) assembly powered by inductive coupling to induce ACEK effects at appropriate frequencies to motivate drugs wirelessly. A signal generator produces the modulating signal, which multiplies with the carrier signal to produce the amplitude modulated (AM) signal...
October 2016: Biomedical Microdevices
https://www.readbyqxmd.com/read/27531590/effect-of-inhibition-on-tyrosinase-and-melanogenesis-of-agastache-rugosa-kuntze-by-lactic-acid-bacteria-fermentation
#2
Nam Young Kim, Hee Souk Kwon, Hyeon Yong Lee
BACKGROUND: This work presents the first report that A. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with Lactobacillus rhamnosus and Lactobacillus paracasei. It was found that the tyrosinase and melanogenesis inhibition was correlated with antioxidant activity of acacetin, the major biologically active substances in A. rugosa. AIMS: we pursued an improvement in tyrosinase and melanogenesis inhibition of A...
August 16, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27466806/social-learning-in-the-real-world-over-imitation-occurs-in-both-children-and-adults-unaware-of-participation-in-an-experiment-and-independently-of-social-interaction
#3
Andrew Whiten, Gillian Allan, Siobahn Devlin, Natalie Kseib, Nicola Raw, Nicola McGuigan
The current study avoided the typical laboratory context to determine instead whether over-imitation-the disposition to copy even visibly, causally unnecessary actions-occurs in a real-world context in which participants are unaware of being in an experiment. We disguised a puzzle-box task as an interactive item available to the public within a science engagement zone of Edinburgh Zoo. As a member of the public approached, a confederate acting as a zoo visitor retrieved a reward from the box using a sequence of actions containing both causally relevant and irrelevant elements...
2016: PloS One
https://www.readbyqxmd.com/read/27409452/optimal-channels-for-channelized-quadratic-estimators
#4
Meredith K Kupinski, Eric Clarkson
We present a new method for computing optimized channels for estimation tasks that is feasible for high-dimensional image data. Maximum-likelihood (ML) parameter estimates are challenging to compute from high-dimensional likelihoods. The dimensionality reduction from M measurements to L channels is a critical advantage of channelized quadratic estimators (CQEs), since estimating likelihood moments from channelized data requires smaller sample sizes and inverting a smaller covariance matrix is easier. The channelized likelihood is then used to form ML estimates of the parameter(s)...
June 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27386010/clinical-and-spectrophotometric-evaluation-of-led-and-laser-activated-teeth-bleaching
#5
R Lo Giudice, G Pantaleo, A Lizio, U Romeo, G Castiello, G Spagnuolo, G Lo Giudice
BACKGROUND: Auxiliary power sources (LED and laser) are used in in-office teeth bleaching techniques to accelerate the redox reaction of the whitening gel to increase ease of use, to improve comfort and safety, and to decrease the procedure time. OBJECTIVE: The aim this study is to evaluate the efficiency of the teeth whitening procedures performed with hydrogen peroxide and carbamide peroxide, LED or Laser activated. METHOD: 18 patients, affected by exogenous dyschromia, were treated with a bleaching agent composed by 35% hydrogen peroxide and 10% carbamide peroxide...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27088670/temporal-decorrelation-by-sk-channels-enables-efficient-neural-coding-and-perception-of-natural-stimuli
#6
Chengjie G Huang, Zhubo D Zhang, Maurice J Chacron
It is commonly assumed that neural systems efficiently process natural sensory input. However, the mechanisms by which such efficient processing is achieved, and the consequences for perception and behaviour remain poorly understood. Here we show that small conductance calcium-activated potassium (SK) channels enable efficient neural processing and perception of natural stimuli. Specifically, these channels allow for the high-pass filtering of sensory input, thereby removing temporal correlations or, equivalently, whitening frequency response power...
April 18, 2016: Nature Communications
https://www.readbyqxmd.com/read/26968117/the-effect-of-bleaching-gel-and-940%C3%A2-nm-and-980%C3%A2-nm-diode-lasers-photoactivation-on-intrapulpal-temperature-and-teeth-whitening-efficiency
#7
Tamara S Al-Karadaghi, Asmaa A Al-Saedi, Mohammed A Al-Maliky, Ali S Mahmood
This in vitro study aimed to investigate the whitening efficacy of 940 nm and 980 nm diode laser photoactivation in tooth bleaching by analysing pulp chamber temperature, as well as the change in tooth colour. Root canals of thirty extracted human lower premolars were prepared. Laserwhite* 20 bleaching agent containing 38% of hydrogen peroxide was photoactivated with 7 W output power of 940 nm and 980 nm diode lasers for 120 s. Bleaching gel reduced 27-29% of the temperature from reaching the pulp chamber...
December 2016: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/26899308/action-of-ellagic-acid-on-the-melanin-biosynthesis-pathway
#8
Carmen Vanessa Ortiz-Ruiz, Jose Berna, Jose Tudela, Ramon Varon, Francisco Garcia-Canovas
BACKGROUND: Tyrosinase is an enzyme involved in the first steps of the melanogenesis process. It catalyzes the hydroxylation of monophenols to o-diphenols and the oxidation of the latter to o-quinones. Ellagic acid (EA) is a phenolic compound which has been described as a tyrosinase inhibitor and is used in the cosmetic industry as a whitening agent. However, it has hydroxyl groups in ortho position and could act as a substrate rather than inhibitor. This aspect should be taken into consideration when using this compound as a cosmetic ingredient due to the reactive character of o-quinones...
May 2016: Journal of Dermatological Science
https://www.readbyqxmd.com/read/26876390/in-vitro-comparative-study-of-two-different-bleaching-agents-on-micro-hardness-dental-enamel
#9
Nazish Fatima, Syed Yawar Ali Abidi, Ashraf Ali Meo
OBJECTIVE: To evaluate the effect of home-use bleaching agent containing 16% Carbamide Peroxide (CP) and in-office bleaching agent containing 38% Hydrogen Peroxide (HP) on enamel micro-hardness. STUDY DESIGN: An in vitroexperimental study. PLACE AND DURATION OF STUDY: Department of Operative Dentistry and Science of Dental Materials at Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences and Material Engineering Department of NED University of Engineering and Technology, Karachi, from July to December 2014...
February 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/26794704/clinical-evaluation-of-different-desensitizing-agents-in-home-bleaching-gels
#10
Jussara Karina Bernardon, Marceli Vieira Martins, Gabrielle Branco Rauber, Sylvio Monteiro Junior, Luiz Narciso Baratieri
STATEMENT OF PROBLEM: The influence of different compositions of desensitizing agents in whitening gels should be evaluated. PURPOSE: The purpose of this clinical trial was to compare the effectiveness of 4 carbamide peroxide (CP)-based bleaching gels containing desensitizing agents regarding the degree of bleaching, tooth sensitivity, degree of participant satisfaction, and gingival irritation. MATERIAL AND METHODS: The maxillary arch of the 50 participants was bleached using a split mouth, home-bleaching technique...
June 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/26787023/in-vitro-comparative-study-of-in-office-and-home-bleaching-agents-on-surface-micro-morphology-of-enamel
#11
Nazish Fatima
OBJECTIVE: To evaluate the effect of home-use bleaching agent containing 16% Carbamide Peroxide (CP) and in-office bleaching agent with 38% Hydrogen Peroxide (HP) on surface micro-morphology of enamel. STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: The discs were prepared at Material Engineering Department of NED University of Engineering and Technology, Karachi, and surface morphology was analyzed at Centralized Science Laboratory of Karachi University, Pakistan...
January 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/26633645/mirrored-stdp-implements-autoencoder-learning-in-a-network-of-spiking-neurons
#12
Kendra S Burbank
The autoencoder algorithm is a simple but powerful unsupervised method for training neural networks. Autoencoder networks can learn sparse distributed codes similar to those seen in cortical sensory areas such as visual area V1, but they can also be stacked to learn increasingly abstract representations. Several computational neuroscience models of sensory areas, including Olshausen & Field's Sparse Coding algorithm, can be seen as autoencoder variants, and autoencoders have seen extensive use in the machine learning community...
December 2015: PLoS Computational Biology
https://www.readbyqxmd.com/read/26526961/intra-pulpal-temperature-rise-of-different-tooth-types-during-dental-bleaching-supported-by-an-er-cr-ysgg-laser-a-pilot-study
#13
D Strakas, K Tolidis, E Koliniotou-Koumpia, L Vanweersch, R Franzen, N Gutknecht
The purpose of this pilot in vitro study was to evaluate the temperature increase in the pulp chamber of the teeth, during Er,Cr:YSGG bleaching, as well as to show which teeth are the most susceptible in terms of pulp temperature increase during laser-activated bleaching treatment. Although Er:YAG studies have been published on this subject, it is the first time Er,Cr:YSGG wavelength is tested. Fifteen teeth were tested--3 each of the following--(maxillary central incisors, lateral incisors, canines, premolars and mandibular incisors)...
January 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/26492089/optimized-31-p-mrs-in-the-human-brain-at-7%C3%A2-t-with-a-dedicated-rf-coil-setup
#14
Bart L van de Bank, Stephan Orzada, Frits Smits, Miriam W Lagemaat, Christopher T Rodgers, Andreas K Bitz, Tom W J Scheenen
The design and construction of a dedicated RF coil setup for human brain imaging ((1)H) and spectroscopy ((31)P) at ultra-high magnetic field strength (7 T) is presented. The setup is optimized for signal handling at the resonance frequencies for (1)H (297.2 MHz) and (31)P (120.3 MHz). It consists of an eight-channel (1)H transmit-receive head coil with multi-transmit capabilities, and an insertable, actively detunable (31)P birdcage (transmit-receive and transmit only), which can be combined with a seven-channel receive-only (31)P array...
November 2015: NMR in Biomedicine
https://www.readbyqxmd.com/read/26483537/experimental-studies-illuminate-the-cultural-transmission-of-percussive-technologies-in-homo-and-pan
#15
REVIEW
Andrew Whiten
The complexity of Stone Age tool-making is assumed to have relied upon cultural transmission, but direct evidence is lacking. This paper reviews evidence bearing on this question provided through five related empirical perspectives. Controlled experimental studies offer special power in identifying and dissecting social learning into its diverse component forms, such as imitation and emulation. The first approach focuses on experimental studies that have discriminated social learning processes in nut-cracking by chimpanzees...
November 19, 2015: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/26450473/kinetic-characterization-of-oxyresveratrol-as-a-tyrosinase-substrate
#16
Carmen Vanessa Ortiz-Ruiz, Manuel Ballesta de Los Santos, Jose Berna, Jose Fenoll, Pedro Antonio Garcia-Ruiz, Jose Tudela, Francisco Garcia-Canovas
Oxyresveratrol is a stilbenoid described as a powerful inhibitor of tyrosinase and proposed as skin-whitening and anti-browning agent. However, the enzyme is capable of acting on it, considering it as a substrate, as it has been proved in the case of its analogous resveratrol. Tyrosinase hydroxylates the oxyresveratrol to an o-diphenol and oxidizes the latter to an o-quinone, which finally isomerizes to p-quinone. For these reactions to take place the presence of the Eox (oxy-tyrosinase) form is necessary. The kinetic analysis of the proposed mechanism has allowed the kinetic characterization of this molecule as a substrate of tyrosinase, affording a catalytic constant of 5...
November 2015: IUBMB Life
https://www.readbyqxmd.com/read/26390051/effects-of-microbubble-size-on-ultrasound-induced-transdermal-delivery-of-high-molecular-weight-drugs
#17
Ai-Ho Liao, Hsin-Chiao Ho, Yi-Chun Lin, Hang-Kang Chen, Chih-Hung Wang
The transdermal delivery of a wide range of high-molecular-weight drugs is limited by the stratum corneum layer of the epidermis representing a significant barrier to penetration across the skin. This study first determined the different effects of different-size ultrasound (US) contrast agents and microbubbles (MBs) for enhancing the transdermal delivery of high-molecular-weight drugs. The effects of US-mediated different-size (1.4, 2.1, and 3.5 μm) MBs (as a contrast agent) and ascorbyl tetraisopalmitate (VC-IP) on enhancing skin transdermal delivery were demonstrated both in vitro and in vivo...
2015: PloS One
https://www.readbyqxmd.com/read/26366588/action-recognition-through-discovering-distinctive-action-parts
#18
Feifei Chen, Nong Sang, Xiaoqin Kuang, Haitao Gan, Changxin Gao
Recent methods based on midlevel visual concepts have shown promising capabilities in the human action recognition field. Automatically discovering semantic entities such as action parts remains challenging. In this paper, we present a method of automatically discovering distinctive midlevel action parts from video for recognition of human actions. We address this problem by learning and selecting a collection of discriminative and representative action part detectors directly from video data. We initially train a large collection of candidate exemplar-linear discriminant analysis detectors from clusters obtained by clustering spatiotemporal patches in whitened space...
February 1, 2015: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/26330939/microhardness-of-demineralized-enamel-following-home-bleaching-and-laser-assisted-in-office-bleaching
#19
Majid Ghanbarzadeh, Farzaneh Ahrari, Majid Akbari, Haniye Hamzei
BACKGROUND: There is little data regarding the effect of tooth whitening on microhardness of white spot lesions. This study was conducted to investigate the effect of home-bleaching and laser-assisted in-office bleaching on microhardness of demineralized enamel. MATERIAL AND METHODS: Forty bovine incisors were selected and immersed in a demineralizing solution for 12 weeks to induce white spot lesions. Enamel blocks were prepared and randomly assigned to two groups of 20 each...
July 2015: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/26212958/middle-infrared-stabilization-of-individual-rice-bran-milling-fractions
#20
Neşe Yılmaz
The aim of this study was to determine the composition and hydrolytic deterioration behavior of rice bran fractions which were obtained individually from different rice whitening mills. Additionally, stabilization of these bran fractions individually with middle infrared radiation and its effects on the contents of tocopherols and γ-oryzanol were investigated. FFA content of the crude and stabilized bran fractions that were obtained from the last whitening and polishing steps was higher either in the beginning or in the end of the storage compared to the others obtained in the first steps of whitening...
January 1, 2016: Food Chemistry
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