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https://www.readbyqxmd.com/read/28088129/in-vitro-eye-irritation-testing-using-the-open-source-reconstructed-hemicornea-a-ring-trial
#1
Karsten R Mewes, Maria Engelke, Michaela Zorn-Kruppa, Melinda Bartok, Rashmi Tandon, Johanna M Brandner, Dirk Petersohn
Aim of the present ring trial was to prove whether two new methodological approaches for the in vitro classification of eye irritating chemicals can be reliably transferred from the developers' laboratories to other sites.Both test methods are based on the well-established open source reconstructed 3D hemicornea models. In the first approach, the initial depth of injury in the hemicornea model after chemical treatment is derived from the quantitative analysis of histological sections. In the second approach tissue viability, as a measure for corneal damage after chemical treatment, is analyzed separately for epithelium and stroma of the hemicornea model...
January 14, 2017: ALTEX
https://www.readbyqxmd.com/read/28079655/microarchitecture-of-schlemm-canal-before-and-after-selective-laser-trabeculoplasty-in-enhanced-depth-imaging-optical-coherence-tomography
#2
Alon Skaat, Michael S Rosman, Jason L Chien, Mark P Ghassibi, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To characterize the in vivo effect of selective laser trabeculoplasty (SLT) on the Schlemm canal (SC) in eyes with primary open-angle glaucoma (POAG). MATERIALS AND METHODS: Eighty-one serial horizontal enhanced depth imaging optical coherence tomograph B-scans (interval between B-scans, ∼35 μm) of the nasal corneoscleral limbus were obtained before and 4 weeks after SLT. Fifty B-scans in the overlapping regions before and after SLT were selected for analysis based on the structures of aqueous and blood vessels as landmarks...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28048308/we-de-bra-01-science-council-junior-investigator-competition-winner-acceleration-of-a-limited-angle-intrafraction-verification-live-system-using-adaptive-prior-knowledge-based-image-estimation
#3
Y Zhang, F Yin, Y Zhang, L Ren
PURPOSE: To develop an adaptive prior knowledge based image estimation method to reduce the scan angle needed in the LIVE system to reconstruct 4D-CBCT for intrafraction verification. METHODS: The LIVE system has been previously proposed to reconstructs 4D volumetric images on-the-fly during arc treatment for intrafraction target verification and dose calculation. This system uses limited-angle beam's eye view (BEV) MV cine images acquired from the treatment beam together with the orthogonally acquired limited-angle kV projections to reconstruct 4D-CBCT images for target verification during treatment...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047157/th-ab-202-01-daily-lung-tumor-motion-characterization-on-epids-using-a-markerless-tiling-model
#4
T Rozario, T Chiu, W Lu, M Chen, Y Yan, S Bereg, W Mao
PURPOSE: Tracking lung tumor motion in real time allows for target dose escalation while simultaneously reducing dose to sensitive structures, thus increasing local control without increasing toxicity. We present a novel intra-fractional markerless lung tumor tracking algorithm using MV treatment beam images acquired during treatment delivery. Strong signals superimposed on the tumor significantly reduced the soft tissue resolution; while different imaging modalities involved introduce global imaging discrepancies...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046263/su-f-t-620-development-of-a-convolution-superposition-dose-engine-for-cyberknife-system
#5
Y Li, B Liu, T Song, S Xu, J Piao, B Liang, X Xu, B Guo, R Wei, F Zhou
PURPOSE: Current CyberKnife treatment planning system (TPS) provided two dose calculation algorithms: Ray-tracing and Monte Carlo. Ray-tracing algorithm is fast, but less accurate, and also can't handle irregular fields since a multi-leaf collimator system was recently introduced to CyberKnife M6 system. Monte Carlo method has well-known accuracy, but the current version still takes a long time to finish dose calculations. The purpose of this paper is to develop a GPU-based fast C/S dose engine for CyberKnife system to achieve both accuracy and efficiency...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045820/magnet-retained-orbital-prosthesis-using-a-dental-implant
#6
Soung Min Kim
The loss of an eye and the associated facial disharmony has major physical, psychological, and social consequences for patients undergoing orbital exenteration. A magnet-retained prosthesis with an implant has various advantages over both adhesive and spectacle-retained prostheses for reconstruction of the exenterated orbit.The author demonstrates one representative patient with our orbital reconstruction patients with magnetic implants, which will be applied to various maxillofacial prosthesis strategies in the near future...
December 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28040528/role-of-diagnostic-endoscopy-in-posterior-segment-evaluation-for-definitive-prognostication-in-eyes-with-corneal-opacification
#7
Rajeev R Reddy Pappuru, Mudit Tyagi, Remya M Paulose, Vivek P Dave, Taraprasad Das, Jay Chhablani, Raja Narayanan, Rushil K Saxena, Divya Balakrishnan, Sayan Basu, Virender S Sangwan
PURPOSE: Direct visualization of the posterior segment is not possible with conventional imaging techniques in eyes with corneal opacification. This study evaluated the efficacy of video-endoscopy in visualising and hence prognosticating the visual outcomes in such eyes . DESIGN: Prospective non-comparative consecutive interventional case series. METHODS: This study included 64 eyes of 64 patients with corneal opacification who underwent diagnostic ophthalmic endoscopy procedure from March 2014 to May 2016...
December 28, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28031146/visual-perspective-during-remembering-erp-evidence-of-familiarity-based-source-monitoring
#8
P Andrew Leynes, Ben Askin, Joshua D Landau
Autobiographical recollections are accompanied by visual perspectives that can be either a view through the person's own eyes (first-person) or a view that integrates visual characteristics of the rememberer into the reconstructed scene (third-person). Some have argued that a third-person perspective serves as a coping mechanism allowing the person to distance themselves from details of painful memories. The study reported here created first- and third-person memories in a novel experimental paradigm. Later, participants discriminated between these perspectives on a source memory test while event-related potentials (ERPs) were recorded...
December 10, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28030571/multidisciplinary-identification-of-the-controversial-freedom-fighter-j%C3%A3-rg-jenatsch-assassinated-1639-in-chur-switzerland
#9
Martin Haeusler, Cordula Haas, Sandra Lösch, Negahnaz Moghaddam, Igor M Villa, Susan Walsh, Manfred Kayser, Roger Seiler, Frank Ruehli, Manuel Janosa, Christina Papageorgopoulou
Jörg Jenatsch, a leading freedom fighter during the Thirty Year's War in Graubünden, Switzerland, was assassinated on carnival 1639. Jenatsch's controversial biography and the unclear circumstances of his death inspired the formation of various legends, novels and films. In 1959, a skeleton discovered in the cathedral of Chur with remains of wealthy baroque clothing was tentatively attributed to Jenatsch. Here, we reassess the skeleton based on a new exhumation. Our multidisciplinary analysis and the head injuries are consistent with reports of the eyewitnesses of the crime, demonstrating that Jenatsch was killed from behind with a semi-sharp implement, supposedly an axe, as well as by a blow with a broad-surfaced object...
2016: PloS One
https://www.readbyqxmd.com/read/28027179/sliced-costochondral-chip-grafts-in-posttraumatic-enophthalmos-correction
#10
Tae-Hoon Kim, Ie-Hyon Park, Sa-Hyeok Hong, Seok-Chan Eun
BACKGROUND: Posttraumatic enophthalmos is a relatively common problem following orbitozygomatic fractures. However, inadequate long-term results are frequently observed due to the difficulty of performing intraoperative fine adjustments to soft-tissue volume and orbital size and gradual absorption of some grafted materials. Here, the authors describe an efficient method of enophthalmos correction using sliced costochondral bone and cartilage combination grafts. METHODS: From 2005 to 2011, the authors corrected enophthalmos in 12 patients using sliced costochondral grafts...
December 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28026772/real-time-3d-eye-performance-reconstruction-for-rgbd-cameras
#11
Quan Wen, Feng Xu, Jun-Hai Yong
This paper proposes a real-time method for 3D eye performance reconstruction using a single RGBD sensor. Combined with facial surface tracking, our method generates more pleasing facial performance with vivid eye motions. In our method, a novel scheme is proposed to estimate eyeball motions by minimizing the differences between a rendered eyeball and the recorded image. Our method considers and handles different appearances of human irises, lighting variations and highlights on images via the proposed eyeball model and the L0-based optimization...
December 19, 2016: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28024847/dark-field-imaging-recent-developments-and-potential-clinical-applications
#12
Masami Ando, Naoki Sunaguchi, Daisuke Shimao, Adam Pan, Tetsuya Yuasa, Kensaku Mori, Yoshifumi Suzuki, Ge Jin, Jong-Ki Kim, Jae-Hong Lim, Seung-Jun Seo, Shu Ichihara, Norihiko Ohura, Rajiv Gupta
This paper describes an X-ray phase contrast imaging technique using analyzer-based optics called X-ray Dark-Field Imaging that has been under development for the past 10years. We describe the theory behind XDFI, the X-ray optics required for implementing it in practice, and algorithms used for 2D, 2.5D, and 3D image reconstruction. The XDFI optical chain consists of an asymmetrically cut, Bragg-type monochromator-collimator that provides a planar monochromatic X-ray beam, a positioning stage for the specimens, a Laue-case angle analyzer, and one or two cameras to capture the dark and bright field images...
December 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/28018739/active-passive-path-length-encoded-apple-doppler-oct
#13
Andreas Wartak, Richard Haindl, Wolfgang Trasischker, Bernhard Baumann, Michael Pircher, Christoph K Hitzenberger
We present a novel active-passive path-length encoded (APPLE) swept source Doppler optical coherence tomography (DOCT) approach, enabling three-dimensional velocity vector reconstruction of moving particles without prior knowledge of the orientation of motion. The developed APPLE DOCT setup allows for non-invasive blood flow measurements in vivo and was primarily designed for quantitative human ocular blood flow investigations. The system's performance was demonstrated by in vitro flow phantom as well as in vivo retinal vessel bifurcation measurements...
December 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/28005755/management-of-zygomatic-fractures-in-young-patients-technical-modifications-for-aesthetic-and-functional-results
#14
Antonio Cortese, Giuseppe D'Alessio, Sergio Brongo, Maurizio Gargiulo, Pier Paolo Claudio
INTRODUCTION: The zygomaticomaxillary complex is very vulnerable to injury because of its intrinsically prominent convexity. There are 2 different surgical approaches for the therapy of these fractures: closed reduction and open reduction. In the open reduction 2 or 3 fixation points with related incisions are usually necessary in dislocated fractures: osteosynthesis must be performed starting from zygomaticofrontal suture when dislocated at this site, followed by zygomatic body fixation on the anterior sinus wall, anterior orbital floor margin fixation, and finally orbital floor reconstruction in case of eye globe dislocation with diplopia...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005719/age-related-clinical-outcome-after-macular-hole-surgery
#15
Yonguk Kim, Eung Suk Kim, Seung-Young Yu, Hyung Woo Kwak
PURPOSE: To evaluate functional and anatomical retinal recovery according to patient age using spectral domain optical coherence tomography in eyes with surgically closed macular holes. METHODS: We retrospectively studied 83 eyes with anatomically closed idiopathic macular holes after surgery confirmed by spectral domain optical coherence tomography. Patients were divided into four subgroups based on age (Group 1: ≤ 60, Group 2: 61-65, Group 3: 66-70, Group 4: > 70)...
January 2017: Retina
https://www.readbyqxmd.com/read/28001037/photoinitiation-and-inhibition-under-monochromatic-green-light-for-storage-of-colored-3d-images-in-holographic-polymer-dispersed-liquid-crystals
#16
Guannan Chen, Mingli Ni, Haiyan Peng, Feihong Huang, Yonggui Liao, Mingkui Wang, Jintao Zhu, V A L Roy, Xiaolin Xie
Holographic photopolymer composites have garnered a great deal of interest in recent decades, not only because of their advantageous light sensitivity but also due to their attractive capabilities of realizing high capacity three-dimensional (3D) data storage that is long-term stable within two-dimensional (2D) thin films. For achieving high performance holographic photopolymer composites, it is of critical importance to implement precisely spatiotemporal control over the photopolymerization kinetics and gelation during holographic recording...
January 5, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27992167/the-eye-of-the-medusa-xrf-imaging-reveals-unknown-traces-of-antique-polychromy
#17
Matthias Alfeld, Maud Mulliez, Philippe Martinez, Kevin Cain, Philippe Jockey, Philippe Walter
The colorful decoration of statues and buildings in antique times is commonly described by the term Antique Polychromy. It is well known among scholars but less so in the interested public and its exact form is subject of ongoing research. In this paper we discuss results obtained from the Frieze of the Siphnian Treasury from the Sanctuary of Delphi (Greece). We will present the first applica-tion of a mobile instrument for macro-XRF imaging in the investigation of the Antique Polychromy and show that it allows to find significant traces not visible to the naked eye and not detectable by XRF spot measurements or any other mobile, non-invasive method...
December 19, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27984548/capillary-nonperfusion-and-photoreceptor-loss-in-branch-retinal-vein-occlusion-spatial-correlation-and-morphologic-characteristics
#18
Menelaos G Kanakis, Konstantina Giannouli, Konstantinos Andreanos, Dimitrios Papaconstantinou, Chrysanthi Koutsandrea, Ioannis Ladas, Ilias Georgalas, Petros Petrou, Athanasios I Kotsolis
PURPOSE: To evaluate the photoreceptor layer in eyes with branch retinal vein occlusion associated with macular ischemia, using a method of en face optical coherence tomography (OCT) representation of the ellipsoid zone. METHODS: Customized macular OCT scans of 9 patients (10 eyes) with branch retinal vein occlusion and macular ischemia were exported and subsequently postprocessed (removal of vascular and cystic spaces' shadows, segmentation, and alignment to the retinal pigment epithelium)...
December 14, 2016: Retina
https://www.readbyqxmd.com/read/27984217/using-levator-aponeurosis-to-create-physiologically-natural-double-eyelid-a-new-reconstruction-technique-based-on-three-key-factors-in-double-eyelid-formation
#19
Lin Lu, Ming Zhu, Xusong Luo, Qun Yang, Xi Wang, Jun Yang, Fei Liu
BACKGROUND: Double eyelidplasty has 3 key factors: motor power, connecting tissue, and skin adhesion. OBJECTIVE: To create natural double eyelid, new anatomy structure should be rebuilt according to physiological double eyelid in these 3 aspects. METHODS: Levator aponeurosis is used as "connecting tissue" to transmit dynamic "motor power" of levator muscle to upper eyelid, and "skin adhesion" is induced between levator aponeurosis and skin in a plane manner...
December 14, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27977837/optical-coherence-tomography-angiography-in-a-normal-iris
#20
Davide Allegrini, Giovanni Montesano, Alfredo Pece
BACKGROUND AND OBJECTIVE: Optical coherence tomography angiography (OCTA) is a new imaging technique for examining the macular region in many retinal diseases. The aim of this study was to assess the applicability of OCTA to detect iris vascularization. PATIENTS AND METHODS: The irises of 28 eyes of 14 patients were examined with AngioVue OCT (Optovue, Fremont, CA). The usual technique was modified using the AngioRetina mode, but with the anterior segment optical adaptor lens, and without autofocus, while making manual adjustments...
December 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
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