keyword
MENU ▼
Read by QxMD icon Read
search

Breast lesions

keyword
https://www.readbyqxmd.com/read/28718395/ultrasound-guided-wire-localisation-to-facilitate-removal-of-an-abnormal-neck-lymph-node-a-technical-note
#1
J Golding, P Kirkland, D Howlett
BACKGROUND: Ultrasound-guided wire localisation is a technique that is well established in breast surgery, but is not well described in head and neck practice. It can be used to locate impalpable lesions for surgical removal, without the need for more extensive surgery. METHOD: This paper describes a case where the technique was used to assist in the removal of an impalpable but radiologically abnormal lymph node. CONCLUSION: The technique offers a safe and effective method for removing lesions within the head and neck...
July 18, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28718332/a-peculiar-form-of-breast-fat-necrosis-simulating-hyaline-ring-granuloma-so-called-pulse-granuloma-a-rare-complication-of-hyperparathyroidism
#2
Maria García-Martos, Angel Panizo-Santos
Pulse granuloma is a rare, foreign body inflammatory reaction that occurs mainly in the oral cavity. It is exceedingly rare elsewhere, with only isolated cases described in the literature. We report the case of a 79-year-old woman with a history of normocalcemic hyperparathyroidism who presented to our hospital with a painful 4-cm lump in the upper quadrants-upper outer quadrant of her left breast. The clinical and radiological (BIRADS-5) findings were indicative of a malignant lesion. However, core needle biopsy revealed features simulating hyaline ring granuloma (pulse granuloma-like)...
July 1, 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28715278/bi-rads-category-3-comparison-probably-benign-category-after-recall-from-screening-before-and-after-implementation-of-digital-breast-tomosynthesis
#3
Elizabeth S McDonald, Anne Marie McCarthy, Susan P Weinstein, Mitchell D Schnall, Emily F Conant
Purpose To evaluate Breast Imaging Reporting and Data System (BI-RADS) category 3 assessment at diagnostic examination after recall from screening in a large urban population after implementation of digital breast tomosynthesis (DBT) by focusing both on overall use and use stratified by recalled finding type and outcome at 2 years. Materials and Methods This was an intuitional review board-approved and HIPAA-compliant retrospective review of 10 728 digital mammography (DM) examinations from September 1, 2010, to August 30, 2011, and 15 571 screening DBT examinations from October 1, 2011, to February 28, 2013...
July 17, 2017: Radiology
https://www.readbyqxmd.com/read/28714966/nanoscale-imaging-of-clinical-specimens-using-pathology-optimized-expansion-microscopy
#4
Yongxin Zhao, Octavian Bucur, Humayun Irshad, Fei Chen, Astrid Weins, Andreea L Stancu, Eun-Young Oh, Marcello DiStasio, Vanda Torous, Benjamin Glass, Isaac E Stillman, Stuart J Schnitt, Andrew H Beck, Edward S Boyden
Expansion microscopy (ExM), a method for improving the resolution of light microscopy by physically expanding a specimen, has not been applied to clinical tissue samples. Here we report a clinically optimized form of ExM that supports nanoscale imaging of human tissue specimens that have been fixed with formalin, embedded in paraffin, stained with hematoxylin and eosin, and/or fresh frozen. The method, which we call expansion pathology (ExPath), converts clinical samples into an ExM-compatible state, then applies an ExM protocol with protein anchoring and mechanical homogenization steps optimized for clinical samples...
July 17, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28713607/primary-osteosarcoma-of-the-breast-arising-in-an-intraductal-papilloma
#5
Khalefa Ali Alghofaily, Musab Hamoud Almushayqih, Muhannad Faleh Alanazi, Abdullah Abdulrahman Bin Salamah, Halldor Benediktsson
INTRODUCTION: Primary osteosarcoma of the breast is extremely rare, and an osteosarcoma arising from an intraductal papilloma is exceptional. CASE PRESENTATION: A 72-year-old Saudi Arabian woman presented with a solid, bone-containing breast mass that was diagnosed as primary osteosarcoma of the breast on biopsy. She had a history of untreated intraductal papilloma. Treatment was completed with a modified mastectomy after excluding extramammary metastases. However, she subsequently developed multiple recurrent lesions at the same site...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28711994/-18-f-fdg-pet-ct-features-for-the-molecular-characterization-of-primary-breast-tumors
#6
Lidija Antunovic, Francesca Gallivanone, Martina Sollini, Andrea Sagona, Alessandra Invento, Giulia Manfrinato, Margarita Kirienko, Corrado Tinterri, Arturo Chiti, Isabella Castiglioni
PURPOSE: The aim of this study was to evaluate the role of imaging features derived from [(18)F]FDG-PET/CT to provide in vivo characterization of breast cancer (BC). METHODS: Images from 43 patients with a first diagnosis of BC were reviewed. Images were acquired before any treatment. Histological data were derived from pretreatment biopsy or surgical histological specimen; these included tumor type, grade, ER and PgR receptor status, lymphovascular invasion, Ki67 index, HER2 status, and molecular subtype...
July 15, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28709150/mammography-and-ultrasound-effective-features-in-differentiating-basal-like-and-normal-like-subtypes-of-triple-negative-breast-cancer
#7
Zeng Zeng, Chun Jie Hou, Qiao Hong Hu, Ying Liu, Ceng Wang, Ran Wei, Xiao Ming Fan
The aim of our study was to find effective features of mammography and ultrasound in differentiating Basal-like breast cancer (BBC) and Normal-like breast cancer (NBC), two subtypes of triple negative breast cancer (TNBC). From January 2014 to March 2017, we retrospectively reviewed 91 patients who were pathologically confirmed as TNBC. According to immunohistochemical cytokeratin 5/6 (CK5/6) and Epidermal Growth Factor Receptor (EGFR), TNBCs were classified into BBCs group and NBCs group. Both CK5/6 and EGFR were negative defined to be NBC, whereas if any of CK5/6 or EGFR was positive then defined as BBC...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28708818/regional-contrast-enhanced-ultrasonography-ceus-characteristics-of-breast-cancer-and-correlation-with-microvessel-density-mvd
#8
Xiaoling Leng, Guofu Huang, Fucheng Ma, Lanhui Yao
BACKGROUND The aim of this study was to investigate the perfusion characteristics of different breast lesion regions in contrast-enhanced ultrasonography (CEUS). MATERIAL AND METHODS A total of 161 malignant and benign breast lesion cases were subjected to CEUS. Perfusion parameters were analyzed and compared between the central and peripheral lesion regions, and surrounding tissue. Mass section was marked with methylene blue. Samples were subjected to immunohistochemistry, and microvessel density (MVD) was calculated...
July 14, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28708299/shear-wave-elastography-for-surgically-verified-breast-papillary-lesions-is-it-effective-for-differentiation-between-benign-and-malignant-lesions
#9
Hye Jeong Choi, Kyung Hee Ko, Hae Kyoung Jung
OBJECTIVES: To evaluate the effectiveness of shear wave elastography (SWE) for differentiating benign from malignant breast papillary lesions METHODS: B-mode ultrasound (US) and SWE were available in 56 surgically confirmed papillary lesions (48 [85.7%] benign and 8 [14.3%] malignant). The diagnostic performances of US, SWE parameters, and combined US with SWE parameters were calculated by receiver operating characteristic curve analysis and compared. RESULTS: The highest area under the receiver operating characteristic curve (Az ) value for US was 0...
July 14, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28707729/sox11-promotes-invasive-growth-and-dcis-progression
#10
Erik Oliemuller, Naoko Kogata, Philip Bland, Divya Kriplani, Frances Daley, Syed Haider, Vandna Shah, Elinor J Sawyer, Beatrice A Howard
Here, we show that SOX11, an embryonic mammary marker, normally silent in postnatal breast cells, is expressed in many ER-negative (ER-) preinvasive DCIS lesions. Mature mammary epithelial cells engineered to express SOX11 displayed alterations in progenitor cell populations, including an expanded basal-like population with increased ALDH activity, and increased mammosphere-forming capacity. DCIS.com cells engineered to express SOX11 displayed increased ALDH activity, a feature of cancer stem cells. The CD44+/CD24-/ALDH+ cell population was increased in DCIS...
July 14, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/28707718/bracketed-radioactive-seed-localization-vs-bracketed-wire-localization-in-breast-surgery
#11
Monica Da Silva, Jessica Porembka, Ali A Mokdad, Stephen Seiler, James Huth, Aeisha Rivers, Rachel Wooldridge, Amanda Chu, Emily Brown, Jean Bao, Deborah Farr, Meghan Hansen, Alison Unzeitig-Barron, Marilyn Leitch, Roshni Rao
Multiple localizers placed in a bracketed fashion facilitates excision of radiographically extensive breast lesions. In this study, bracketed radioactive seed localization (bRSL) was compared to bracketed wire localization (bWL). We hypothesized that bRSL would achieve adequate margins and decrease re-operation rates with similar or less specimen volumes (SV) than bWL. Retrospective review identified patients who underwent bracketed breast procedures at an academic medical center. Data collected included patient demographics, tumor features, treatment variables, and surgical outcomes...
July 14, 2017: Breast Journal
https://www.readbyqxmd.com/read/28707546/a-computer-aided-diagnosis-cad-scheme-for-pretreatment-prediction-of-pathological-response-to-neoadjuvant-therapy-using-dynamic-contrast-enhanced-mri-texture-features
#12
Valentina Giannini, Simone Mazzetti, Agnese Marmo, Filippo Montemurro, Daniele Regge, Laura Martincich
OBJECTIVES: To assess whether a computer aided diagnosis (CAD) system can predict pathological response (pCR) to neoadjuvant chemotherapy (NAC) prior to treatment using texture features. MATERIALS AND METHODS: Response to treatment of 44 patients was defined according to the histopatology of resected tumour and extracted axillary nodes in two ways: a) pCR+ (Smith's grade=5) vs pCR- (Smith's grade<5); b) pCRN+ (pCR+ and absence of residual lymph node metastases) vs pCRN-...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28706892/primary-osteosarcoma-of-the-breast-a-case-report
#13
Chan Seok Yoon, Sung Soo Kang
Primary osteosarcomas of the breast are extremely uncommon. Here we describe a case of a 77-year-old woman who presented with a hard mass on her right breast. Mammography and breast ultrasound demonstrated a round-shaped calcified mass on the right breast but the features were not definitely diagnostic. For diagnostic purposes, an excisional biopsy was performed and the mass proved to be a primary osteosarcoma of the breast by pathologic findings. PET-CT and whole body bone scan showed neither evidence of metastasis nor underlying bone lesions...
July 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28706762/metastatic-breast-cancer-with-brca-mutation-discovered-by-next-generation-sequencing-responding-to-olaparib
#14
Wajeeha Rizvi, Phu Truong, Quoc Truong
Breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2) mutations are associated with hereditary breast and ovarian cancer syndromes (HBOC). However, certain individuals with breast cancer do not meet high-risk factors for hereditary breast cancer screening based on age, family history, and biology of malignancy. We present a patient with relapsed breast cancer who developed progressive disease with significant tumor burden causing a recurrent pleural effusion. Next-generation sequencing (NGS) done on a tumor biopsy was positive for the BRCA2 mutation...
June 11, 2017: Curēus
https://www.readbyqxmd.com/read/28705330/mucocoele-like-lesions-is-surgical-excision-still-necessary
#15
I Dash, B Dessauvagie, M Hardie, C Saunders, E Wylie
AIM: To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. MATERIALS AND METHODS: A retrospective review of the breast screening database from 1999-2014 was performed. RESULTS: MLL were identified on core biopsy in 113 women (0.6% of those recalled for a core biopsy). The majority (n=100, 88%) had a localised cluster of calcification prompting screening recall...
July 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28702779/clinicopathological-characteristics-of-fallopian-tube-metastases-from-primary-endometrial-cervical-and-nongynecological-malignancies-a-single-institutional-experience
#16
Kiyong Na, Hyun-Soo Kim
This study was aimed at investigating the clinicopathological characteristics of tubal metastases originating from primary endometrial, cervical, and nongynecological malignancies. We performed a 4-year retrospective study in which fallopian tube tissues obtained from 60 patients with tubal metastases were examined. In addition, we compared the number of tubal metastasis cases detected during periods of representative or whole tubal sampling. Twenty-three and 37 tubal metastases were found in cases examined after representative and whole tubal sampling techniques, respectively...
July 13, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28700421/atypical-proliferative-borderline-serous-tumor-in-the-brain-a-case-report
#17
Deyin Xing, Erik G Jenson, Christopher A Zwick, Fausto J Rodriguez, Robert J Kurman
A 59-year-old woman with a remote history of invasive ductal carcinoma of the breast was found on a follow-up computed tomography scan of her brain to have a 1-cm lesion in the right frontal lobe in 2008. In the ensuing years, before her current admission, multiple imaging studies of the brain revealed that the lesion was stable and it was, therefore, interpreted as a small area of encephalomalacia related to a thrombosed cortical vein, a cavernoma, or treated metastatic breast cancer. In 2013, the patient underwent a bilateral salpingo-oophorectomy for ovarian tumors that were diagnosed as bilateral serous cystadenofibromas...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28698632/quality-measurement-of-two-dimensional-shear-wave-speed-imaging-for-breast-lesions-the-associated-factors-and-the-impact-to-diagnostic-performance
#18
Dan-Dan Li, Hui-Xiong Xu, Bo-Ji Liu, Xiao-Wan Bo, Xiao-Long Li, Rong Wu
This study aimed to identify the associated factors for quality measurement (QM) of shear wave speed (SWS) imaging and to validate the additional value of QM in the diagnosis of breast lesions. From September 2014 to February 2015, conventional ultrasound and SWS imaging were performed in 338 women with 361 breast lesions. Binary logistic regression was used to identify associated factors for QM. Sensitivity, specificity and the area under receiver operating characteristic (ROC) curve (AUC) among maximum SWS (SWS max ), QM and SWS max plus QM (SWS max +QM) were compared to validate additional value of QM...
July 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28698404/association-of-conventional-ultrasound-elastography-and-clinicopathological-factors-with-axillary-lymph-node-status-in-invasive-ductal-breast-carcinoma-with-sizes-10-mm
#19
Hui Liu, Guang Xu, Ming-Hua Yao, Huan Pu, Yan Fang, Li-Hua Xiang, Rong Wu
BACKGROUND: To evaluate whether conventional ultrasound, elastography [conventional strain elastography of elasticity imaging, acoustic radiation force impulse induced strain elastography of virtual touch tissue imaging, and a novel two-dimensional shear wave elastography of virtual touch tissue imaging quantification] and clinicopathological factors are associated with axillary lymph node metastasis in invasive ductal breast carcinoma with sizes > 10 mm. MATERIALS AND METHODS: We evaluated 150 breast lesions from 148 patients using the above methods and the clinicopathological factors...
July 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28695812/clinical-and-sonographic-features-of-mammary-paget-s-disease
#20
Yao Wei, Qingli Zhu, Jianchu Li, Yuxin Jiang
Objective To summarize the clinical and sonographic features of mammary Paget's disease (MPD). Methods Totally 34 female patients with pathologically confirmed MPD were retrospectively recruited. According to diagnosis,the clinical data and sonographic findings were reviewed and analyzed. Results Among these 34 patients,7 patients had single MPD; in the remaining 27 patients,16 were accompanied by invasive ductal carcinoma (IDC),7 by ductal carcinoma in situ (DCIS),3 by both IDC and DCIS,and 1 by other pathologic types of carcinoma...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
keyword
keyword
34635
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"