keyword
https://read.qxmd.com/read/38529295/clinical-and-radiological-outcomes-and-analysis-of-failures-of-modular-revisions-stems-at-long-term-follow-up-a-systematic-review-and-meta-analysis
#21
JOURNAL ARTICLE
Michela Saracco, Vincenzo Ciriello, Andrea Fidanza, Giandomenico Logroscino
BACKGROUND: Increasingly hip replacements at young age exposes the patient to an increased risk of failure of the implant over the years. In case of failure, revision specific stems were designed to overcome bone loss. Modularity of these devices is an important resource for the surgeon as they allow the new implant to be better adapted to the patient's anatomy. The purpose of this systematic review is to provide data about the outcome at long-term follow-up (>8 years) of hip modular revision femoral stems...
2024: Annals of joint
https://read.qxmd.com/read/38528982/effects-of-empathy-on-the-bidirectional-relationships-between-problematic-smartphone-use-and-aggression-among-secondary-school-students-a-moderated-network-approach
#22
JOURNAL ARTICLE
Wenxia Wu, Xinyuan Zou, Qihui Tang, Yanqiang Tao, Shujian Wang, Zijuan Ma, Min Li, Gang Liu
BACKGROUND: Existing literature on the relationship between problematic smartphone use (PSU) and aggression has primarily focused on examining their unidirectional association, with limited attention paid to the bidirectional nature of this relationship, particularly when considering the role of empathy. This study employs a novel moderated network approach to examine the bidirectional relationship between problematic smartphone use and aggression, while also investigating the moderating mechanism of empathy...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38528547/evaluation-of-the-diagnostic-performance-of-colposcopy-in-the-detection-of-cervical-high-grade-squamous-intraepithelial-lesions-among-women-with-transformation-zone-type-3
#23
JOURNAL ARTICLE
Xiaoxiao Li, Yunzhi Zhao, Fenfen Xiang, Xinpei Zhang, Zixi Chen, Mengzhe Zhang, Xiangdong Kang, Rong Wu
BACKGROUND: Inaccurate colposcopy diagnosis may lead to inappropriate management and increase the incidence of cervical cancer. This study aimed to evaluate the diagnostic accuracy of colposcopy in the detection of histologic cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in women with transformation zone type 3 (TZ3). METHODS: Records from 764 patients with TZ3 who underwent colposcopy-directed biopsy and/or endocervical curettage in Putuo Hospital China between February 2020 and March 2023 were retrospectively collected...
March 26, 2024: BMC Cancer
https://read.qxmd.com/read/38528339/making-drug-therapy-safer-and-more-effective-is-a-primary-concern-for-pharmacists-everywhere
#24
JOURNAL ARTICLE
Chris Alderman
No abstract text is available yet for this article.
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528338/pharmacogenomics-in-clinical-practice-for-older-people
#25
JOURNAL ARTICLE
Syeda R Hashimi, Olajumoke Babatunde, Khalifa Alrajeh, Richard J Dixon, Aimalohi Okpeku, Elvin T Price
Older people are over-represented among individuals that experience adverse drug reactions (ADR) and adverse drug events (ADE). Furthermore, older people are over-represented among individuals that visit emergency departments and are hospitalized because of ADRs. Moreover, older people are overrepresented among those who suffer ADEs while hospitalized. Finally, older people are among those most likely to have an anaphylactic response to prescription medications. Therefore, older people are prime candidates for efforts aimed at optimizing pharmacotherapeutic outcomes...
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528337/utilizing-pharmacogenomics-results-to-guide-antidepressant-selection-a-case-report
#26
JOURNAL ARTICLE
Nicholas Vernacchia, Nicole Del Toro-Pagán, Chandni Bardolia, Nishita Shah Amin
The case discussion demonstrates the benefit of using Pharmacogenomic (PGx) results to aid in the selection of antidepressant therapy and improve response to treatment. Nearly half of patients diagnosed with major depressive disorder fail initial therapy and may require multiple trials of antidepressants. Genetic variation in several metabolic enzymes contribute to the variable response to antidepressant therapy. PGx testing provides an opportunity to inform antidepressant selection and optimize therapeutic outcomes, while minimizing risk of adverse events...
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528336/pharmacists-role-in-pharmacogenomics-transforming-promise-to-reality-through-perseverance-and-knowledge
#27
JOURNAL ARTICLE
Manju T Beier
No abstract text is available yet for this article.
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528335/chronic-pain-management-in-a-cyp2d6-poor-metabolizer-a-case-report-for-oxycodone
#28
JOURNAL ARTICLE
Deepa Pednekar, Joshua Russell, Chandni Bardolia, David Thacker, Nishita Shah Amin
The objective of this case report is to illustrate pharmacogenomics (PGx)-guided oxycodone treatment, given the conflicting data on the analgesic response from oxycodone in Cytochrome P450 (CYP)2D6 poor metabolizers (PMs). PGx-guided therapy can help improve treatment outcomes. This case report describes a 58-year-old patient who was prescribed oxycodone for chronic pain management. The patient presented with a history of inadequate pain control despite analgesic treatment with oxycodone (morphine milliequivalent [MME] = 22...
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528334/pharmacogenomics-medical-advancement-caught-in-an-ethical-and-policy-quagmire
#29
JOURNAL ARTICLE
Leigh Davitian
No abstract text is available yet for this article.
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528333/utilizing-pharmacogenomics-results-to-improve-statin-associated-muscle-symptoms
#30
JOURNAL ARTICLE
Coral Perez González, Chandni Bardolia, Katie Pizzolato, Nishita Shah Amin
The objective of this aims to demonstrate the advantage of a pharmacogenomics (PGx)-informed medication review in mitigating adverse drug events (ADEs) and optimizing therapeutic outcomes. PGx testing and PGx-informed medication reviews assist in mitigating ADEs. PGx testing was performed on a 68-year-old male presenting with uncontrolled chronic pain. The PGx results highlighted a drug-gene interaction, aiding in identification of the increased risk of statin-associated muscle symptoms (SAMS) attributing to uncontrolled chronic pain...
April 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38528159/larger-or-longer-grants-unlikely-to-push-senior-scientists-towards-high-risk-high-reward-work
#31
Dalmeet Singh Chawla
No abstract text is available yet for this article.
March 25, 2024: Nature
https://read.qxmd.com/read/38527869/-addictions-in-the-elderly-the-viewpoint-of-an-ipa-working-in-empsa
#32
JOURNAL ARTICLE
Sita Gakou
Many elderly people live well and at home, but some require somatic and psychiatric care. Mobile psychiatric teams for the elderly are called upon to intervene with people aged 65-70 and over who are experiencing psychological distress. Among senior citizens, addictive disorders are very common, and are associated with psychiatric and geriatric co-morbidities. Alcohol, tobacco and benzodiazepine use disorders require holistic, individualized care, based on identification, prevention and referral, as well as training and coordination of professionals and caregivers...
2024: Soins. Psychiatrie
https://read.qxmd.com/read/38527342/patient-reported-outcomes-on-subjective-nipple-sensation-after-double-incision-and-periareolar-mastectomy-for-chest-masculinization-subjective-nipple-sensation-after-chest-masculinization
#33
JOURNAL ARTICLE
Amy Chen, Shannon R Garvey, Asha D Nanda, Rosie Friedman, Emmeline Jia, Monica Morgenstern, Sivana Barron, Adam Tobias, Ryan P Cauley
We evaluated patient-reported outcomes to assess for patient and procedural factors associated with postchest masculinization subjective nipple sensation. Patients who underwent double-incision or periareolar mastectomies for chest masculinization by a single senior surgeon (2015-2019) were surveyed at 2 time points regarding postoperative nipple sensation and satisfaction, including patient-reported outcomes using BODY-Q modules (Q-Portfolio.org). Demographic, operative, and postoperative variables were obtained from medical records...
April 1, 2024: Annals of Plastic Surgery
https://read.qxmd.com/read/38527108/access-to-specialized-health-care-services-among-older-canadians
#34
JOURNAL ARTICLE
Md Kamrul Islam, Heather Gilmour
BACKGROUND: Canada is experiencing rapid population aging, which has a wide range of implications, including an increased need for health care services. However, very few studies have examined use of specialized health care services (e.g., visits to medical specialists, non-emergency tests, and surgeries) among older Canadians. DATA AND METHODS: Data from the Canadian Health Survey on Seniors - 2019/2020 were used to examine specialized health care service use among older Canadians...
March 20, 2024: Health Reports
https://read.qxmd.com/read/38527027/mechanisms-of-near-peer-learning-in-a-longitudinal-clerkship-a-grounded-theory-study
#35
JOURNAL ARTICLE
Lauren E Smith, Mary E McBride, Bruce Henschen, Jennifer Bierman, Toshiko Uchida, Walter Eppich
PURPOSE: Many medical schools incorporate longitudinal clerkships, which promote continuity and may offer early clinical exposure during the preclinical curriculum. However, the mechanisms of near-peer learning and how it contributes to the development of clinical skills in longitudinal clinical experiences are less clear. The authors explored how peer-to-peer interactions among medical students influenced their developmental trajectories from nascent clinicians to more seasoned practitioners capable of juggling dual roles of clinical care and clinical supervision within longitudinal clerkships...
March 25, 2024: Academic Medicine
https://read.qxmd.com/read/38526947/detection-of-plagiarism-among-rhinology-scientific-journals
#36
JOURNAL ARTICLE
Ezer H Benaim, Saima Wase, Saif Zaidi, Aurelia Monk, Cristine Klatt-Cromwell, Brian D Thorp, Charles S Ebert, Adam J Kimple, Brent A Senior
Automated plagiarism-checking software can be a valuable tool for detecting plagiarism in manuscripts. Twenty-five of 60 articles (42%) had at least one incidence of plagiarism, predominately text recycling. A "similarity score" ranging from 22% to 35% could be a potential cut-off value when screening submitted manuscripts.
March 25, 2024: International Forum of Allergy & Rhinology
https://read.qxmd.com/read/38526861/the-effect-of-covid-19-fear-on-midwifery-students-anxiety-self-confidence
#37
JOURNAL ARTICLE
Asli Er-Korucu, Fatma Uslu-Sahan, Hacer Alan-Dikmen
BACKGROUND: Several studies have investigated independently of clinical education, it has been emphasized that students experience fear, anxiety, sadness and uncertainty during the pandemic. AIM: This study aimed to investigate the effect of fear of COVID-19 on the level of anxiety and self-confidence of midwifery students who did their clinical internship during the pandemic. METHODS: Convenience sampling yielded 181 senior midwifery students who had experienced clinical internships during the COVID-19 pandemic...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38525929/research-gap-in-esophageal-achalasia-a-narrative-review
#38
JOURNAL ARTICLE
Edoardo Vincenzo Savarino, Renato Salvador, Matteo Ghisa, Amir Mari, Francesca Forattini, Andrea Costantini, Roberto De Giorgio, Giovanni Zaninotto
In recent years, new translational evidence, diagnostic techniques, and innovative therapies have shed new light on esophageal achalasia and revamped the attention on this relatively rare motility disorder. This narrative review aims to highlight the most recent progress and the areas where further research is needed. The four senior authors identified five topics commonly discussed in achalasia management: i.e. pathogenesis, role of functional lumen imaging probe in the diagnostic flow chart of achalasia, how to define the outcome of achalasia treatments, how to manage persistent chest pain after the treatment, and if achalasia patients' may benefit from a regular follow-up...
March 24, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38525784/the-frailty-reduction-via-implementation-of-exercise-nutrition-and-deprescribing-friend-trial-study-protocol-and-recruitment-results
#39
JOURNAL ARTICLE
Michael Inskip, Carolina Almendrales Rangel, Chidiamara Maria Njoku, Fiona Barnett, Isabel Shih, Leonie O'Neill, Maria A Fiatarone Singh, Trinidad Valenzuela
INTRODUCTION: Virtually all adults in aged care facilities are frail, a condition which contributes to falls, cognitive decline, hospitalisation, and mortality. Polypharmacy, malnutrition, sedentariness, and sarcopenia are risk factors amenable to intervention. The Asia-Pacific Frailty Management Guidelines recommend anabolic exercise and the optimisation of medications and nutrition. However, no study has evaluated this best practice intervention triad in aged care. METHODS: The Frailty Reduction via the Implementation of Exercise, Nutrition, and Deprescribing (FRIEND) Trial (ANZCTR No...
March 22, 2024: Methods and Protocols
https://read.qxmd.com/read/38525622/improving-health-outcomes-and-quality-at-the-subdistrict-level-evaluation-of-the-3-feet-model-in-waterberg-district-limpopo-province-south-africa
#40
JOURNAL ARTICLE
H Schneider, F Mukinda, J Cupido, J Wessels, P Kupa, P Leboho, N Nkoana, N Bosch, Y Pillay
BACKGROUND: There is a gap in understanding of potential roles and actions at the subdistrict level to improve quality of care and health outcomes in South Africa (SA). OBJECTIVES: To report on the evaluation of a subdistrict health system-strengthening initiative that aimed to reduce maternal, newborn and child mortality, referred to as the '3 feet model' in Waterberg District, Limpopo Province, SA. The model is centred on systems of real-time morbidity/mortality surveillance and co-ordinated responses...
November 6, 2023: South African Medical Journal
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