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JOURNAL ARTICLE
Gaëlle Blanvillain, Jeffrey M Lorch, Nicolas Joudrier, Stanislaw Bury, Thibault Cuenot, Michael Franzen, Fernando Martínez-Freiría, Gaëtan Guiller, Bálint Halpern, Aleksandra Kolanek, Katarzyna Kurek, Olivier Lourdais, Alix Michon, Radka Musilová, Silke Schweiger, Barbara Szulc, Sylvain Ursenbacher, Oleksandr Zinenko, Joseph R Hoyt
Infectious diseases are influenced by interactions between host and pathogen, and the number of infected hosts is rarely homogenous across the landscape. Areas with elevated pathogen prevalence can maintain a high force of infection and may indicate areas with disease impacts on host populations. However, isolating the ecological processes that result in increases in infection prevalence and intensity remains a challenge. Here we elucidate the contribution of pathogen clade and host species in disease hotspots caused by Ophidiomyces ophidiicola, the pathogen responsible for snake fungal disease, in 21 species of snakes infected with multiple pathogen strains across 10 countries in Europe...
April 10, 2024: Communications Biology
#2
JOURNAL ARTICLE
Daniel Krafft, Clifton G Scarboro, William Hsieh, Colleen Doherty, Peter Balint-Kurti, Michael Kudenov
Automation of plant phenotyping using data from high-dimensional imaging sensors is on the forefront of agricultural research for its potential to improve seasonal yield by monitoring crop health and accelerating breeding programs. A common challenge when capturing images in the field relates to the spectral reflection of sunlight (glare) from crop leaves that, at certain solar incidences and sensor viewing angles, presents unwanted signals. The research presented here involves the convergence of 2 parallel projects to develop a facile algorithm that can use polarization data to decouple light reflected from the surface of the leaves and light scattered from the leaf's tissue...
2024: Plant phenomics: a science partner journal
#3
JOURNAL ARTICLE
A Cole Burton, Christopher Beirne, Kaitlyn M Gaynor, Catherine Sun, Alys Granados, Maximilian L Allen, Jesse M Alston, Guilherme C Alvarenga, Francisco Samuel Álvarez Calderón, Zachary Amir, Christine Anhalt-Depies, Cara Appel, Stephanny Arroyo-Arce, Guy Balme, Avi Bar-Massada, Daniele Barcelos, Evan Barr, Erika L Barthelmess, Carolina Baruzzi, Sayantani M Basak, Natalie Beenaerts, Jonathan Belmaker, Olgirda Belova, Branko Bezarević, Tori Bird, Daniel A Bogan, Neda Bogdanović, Andy Boyce, Mark Boyce, LaRoy Brandt, Jedediah F Brodie, Jarred Brooke, Jakub W Bubnicki, Francesca Cagnacci, Benjamin Scott Carr, João Carvalho, Jim Casaer, Rok Černe, Ron Chen, Emily Chow, Marcin Churski, Connor Cincotta, Duško Ćirović, T D Coates, Justin Compton, Courtney Coon, Michael V Cove, Anthony P Crupi, Simone Dal Farra, Andrea K Darracq, Miranda Davis, Kimberly Dawe, Valerie De Waele, Esther Descalzo, Tom A Diserens, Jakub Drimaj, Martin Duľa, Susan Ellis-Felege, Caroline Ellison, Alper Ertürk, Jean Fantle-Lepczyk, Jorie Favreau, Mitch Fennell, Pablo Ferreras, Francesco Ferretti, Christian Fiderer, Laura Finnegan, Jason T Fisher, M Caitlin Fisher-Reid, Elizabeth A Flaherty, Urša Fležar, Jiří Flousek, Jennifer M Foca, Adam Ford, Barbara Franzetti, Sandra Frey, Sarah Fritts, Šárka Frýbová, Brett Furnas, Brian Gerber, Hayley M Geyle, Diego G Giménez, Anthony J Giordano, Tomislav Gomercic, Matthew E Gompper, Diogo Maia Gräbin, Morgan Gray, Austin Green, Robert Hagen, Robert Bob Hagen, Steven Hammerich, Catharine Hanekom, Christopher Hansen, Steven Hasstedt, Mark Hebblewhite, Marco Heurich, Tim R Hofmeester, Tru Hubbard, David Jachowski, Patrick A Jansen, Kodi Jo Jaspers, Alex Jensen, Mark Jordan, Mariane C Kaizer, Marcella J Kelly, Michel T Kohl, Stephanie Kramer-Schadt, Miha Krofel, Andrea Krug, Kellie M Kuhn, Dries P J Kuijper, Erin K Kuprewicz, Josip Kusak, Miroslav Kutal, Diana J R Lafferty, Summer LaRose, Marcus Lashley, Richard Lathrop, Thomas E Lee, Christopher Lepczyk, Damon B Lesmeister, Alain Licoppe, Marco Linnell, Jan Loch, Robert Long, Robert C Lonsinger, Julie Louvrier, Matthew Scott Luskin, Paula MacKay, Sean Maher, Benoît Manet, Gareth K H Mann, Andrew J Marshall, David Mason, Zara McDonald, Tracy McKay, William J McShea, Matt Mechler, Claude Miaud, Joshua J Millspaugh, Claudio M Monteza-Moreno, Dario Moreira-Arce, Kayleigh Mullen, Christopher Nagy, Robin Naidoo, Itai Namir, Carrie Nelson, Brian O'Neill, M Teague O'Mara, Valentina Oberosler, Christian Osorio, Federico Ossi, Pablo Palencia, Kimberly Pearson, Luca Pedrotti, Charles E Pekins, Mary Pendergast, Fernando F Pinho, Radim Plhal, Xochilt Pocasangre-Orellana, Melissa Price, Michael Procko, Mike D Proctor, Emiliano Esterci Ramalho, Nathan Ranc, Slaven Reljic, Katie Remine, Michael Rentz, Ronald Revord, Rafael Reyna-Hurtado, Derek Risch, Euan G Ritchie, Andrea Romero, Christopher Rota, Francesco Rovero, Helen Rowe, Christian Rutz, Marco Salvatori, Derek Sandow, Christopher M Schalk, Jenna Scherger, Jan Schipper, Daniel G Scognamillo, Çağan H Şekercioğlu, Paola Semenzato, Jennifer Sevin, Hila Shamon, Catherine Shier, Eduardo A Silva-Rodríguez, Magda Sindicic, Lucy K Smyth, Anil Soyumert, Tiffany Sprague, Colleen Cassady St Clair, Jennifer Stenglein, Philip A Stephens, Kinga Magdalena Stępniak, Michael Stevens, Cassondra Stevenson, Bálint Ternyik, Ian Thomson, Rita T Torres, Joan Tremblay, Tomas Urrutia, Jean-Pierre Vacher, Darcy Visscher, Stephen L Webb, Julian Weber, Katherine C B Weiss, Laura S Whipple, Christopher A Whittier, Jesse Whittington, Izabela Wierzbowska, Martin Wikelski, Jacque Williamson, Christopher C Wilmers, Todd Windle, Heiko U Wittmer, Yuri Zharikov, Adam Zorn, Roland Kays
Wildlife must adapt to human presence to survive in the Anthropocene, so it is critical to understand species responses to humans in different contexts. We used camera trapping as a lens to view mammal responses to changes in human activity during the COVID-19 pandemic. Across 163 species sampled in 102 projects around the world, changes in the amount and timing of animal activity varied widely. Under higher human activity, mammals were less active in undeveloped areas but unexpectedly more active in developed areas while exhibiting greater nocturnality...
March 18, 2024: Nature Ecology & Evolution
#4
JOURNAL ARTICLE
Roland Tengölics, Balázs Szappanos, Michael Mülleder, Dorottya Kalapis, Gábor Grézal, Csilla Sajben, Federica Agostini, João Benhur Mokochinski, Balázs Bálint, László G Nagy, Markus Ralser, Balázs Papp
Cellular metabolism evolves through changes in the structure and quantitative states of metabolic networks. Here, we explore the evolutionary dynamics of metabolic states by focusing on the collection of metabolite levels, the metabolome, which captures key aspects of cellular physiology. Using a phylogenetic framework, we profiled metabolites in 27 populations of nine budding yeast species, providing a graduated view of metabolic variation across multiple evolutionary time scales. Metabolite levels evolve more rapidly and independently of changes in the metabolic network's structure, providing complementary information to enzyme repertoire...
March 12, 2024: Proceedings of the National Academy of Sciences of the United States of America
#5
RANDOMIZED CONTROLLED TRIAL
Federico Biavati, Luca Saba, Melinda Boussoussou, Klaus F Kofoed, Theodora Benedek, Patrick Donnelly, José Rodríguez-Palomares, Andrejs Erglis, Cyril Štěchovský, Gintarė Šakalytė, Nada Čemerlić Ađić, Matthias Gutberlet, Jonathan D Dodd, Ignacio Diez, Gershan Davis, Elke Zimmermann, Cezary Kępka, Radosav Vidakovic, Marco Francone, Małgorzata Ilnicka-Suckiel, Fabian Plank, Juhani Knuuti, Rita Faria, Stephen Schröder, Colin Berry, Balazs Ruzsics, Nina Rieckmann, Christine Kubiak, Kristian Schultz Hansen, Jacqueline Müller-Nordhorn, Pál Maurovich-Horvat, Per E Sigvardsen, Imre Benedek, Clare Orr, Filipa Xavier Valente, Ligita Zvaigzne, Vojtěch Suchánek, Antanas Jankauskas, Filip Ađić, Michael Woinke, Diarmaid Cadogan, Iñigo Lecumberri, Erica Thwaite, Mariusz Kruk, Aleksandar N Neskovic, Massimo Mancone, Donata Kuśmierz, Gudrun Feuchtner, Mikko Pietilä, Vasco Gama Ribeiro, Tanja Drosch, Christian Delles, Riccardo Cau, Michael Fisher, Bela Merkely, Charlotte Kragelund, Rosca Aurelian, Stephanie Kelly, Bruno García Del Blanco, Ainhoa Rubio, Bálint Szilveszter, Jens D Hove, Ioana Rodean, Susan Regan, Hug Cuéllar Calabria, István Ferenc Édes, Linnea Larsen, Roxana Hodas, Adriane E Napp, Robert Haase, Sarah Feger, Mahmoud Mohamed, Lina M Serna-Higuita, Konrad Neumann, Henryk Dreger, Matthias Rief, Viktoria Wieske, Matthew J Budoff, Melanie Estrella, Peter Martus, Maria Bosserdt, Marc Dewey
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role in symptomatic patients is less clear. Purpose To assess the prognostic value of CAC scoring for MACE in participants with stable chest pain initially referred for invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from the Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial, conducted between October 2015 and April 2019 across 26 centers in 16 countries, focused on adult patients with stable chest pain referred for ICA...
March 2024: Radiology
#6
JOURNAL ARTICLE
Keng Siang Lee, Balint Borbas, Puneet Plaha, Keyoumars Ashkan, Michael D Jenkinson, Stephen J Price
BACKGROUND: Surgical site infections after craniotomy (SSI-CRANs) are a serious adverse event given the proximity of the wound to the central nervous system. SSI-CRANs are associated with substantial patient morbidity and mortality. Despite the importance and recognition of this event in other surgical fields, there is a paucity of evidence in the neurosurgical literature devoted to SSI-CRAN specifically in patients after brain tumor surgery. METHODS: Systematic searches of Medline, Embase, and Cochrane Central were undertaken...
March 2, 2024: World Neurosurgery
#7
JOURNAL ARTICLE
Maria Bosserdt, Lina M Serna-Higuita, Gudrun Feuchtner, Bela Merkely, Klaus F Kofoed, Theodora Benedek, Patrick Donnelly, José Rodriguez-Palomares, Andrejs Erglis, Cyril Štechovský, Gintare Šakalyte, Nada Cemerlic Adic, Matthias Gutberlet, Jonathan D Dodd, Ignacio Diez, Gershan Davis, Elke Zimmermann, Cezary Kepka, Radosav Vidakovic, Marco Francone, Malgorzata Ilnicka-Suckiel, Fabian Plank, Juhani Knuuti, Rita Faria, Stephen Schröder, Colin Berry, Luca Saba, Balazs Ruzsics, Nina Rieckmann, Christine Kubiak, Kristian Schultz Hansen, Jacqueline Müller-Nordhorn, Bálint Szilveszter, Per E Sigvardsen, Imre Benedek, Clare Orr, Filipa Xavier Valente, Ligita Zvaigzne, Vojtech Suchánek, Antanas Jankauskas, Filip Adic, Michael Woinke, Mark Hensey, Iñigo Lecumberri, Erica Thwaite, Michael Laule, Mariusz Kruk, Aleksandar N Neskovic, Massimo Mancone, Donata Kusmierz, Mikko Pietilä, Vasco Gama Ribeiro, Tanja Drosch, Christian Delles, Maurizio Porcu, Michael Fisher, Melinda Boussoussou, Charlotte Kragelund, Rosca Aurelian, Stephanie Kelly, Bruno Garcia Del Blanco, Ainhoa Rubio, Pál Maurovich-Horvat, Jens D Hove, Ioana Rodean, Susan Regan, Hug Cuellar-Calabria, Levente Molnár, Linnea Larsen, Roxana Hodas, Adriane E Napp, Robert Haase, Sarah Feger, Mahmoud Mohamed, Konrad Neumann, Henryk Dreger, Matthias Rief, Viktoria Wieske, Melanie Estrella, Peter Martus, Harold C Sox, Marc Dewey
IMPORTANCE: The effectiveness and safety of computed tomography (CT) and invasive coronary angiography (ICA) in different age groups is unknown. OBJECTIVE: To determine the association of age with outcomes of CT and ICA in patients with stable chest pain. DESIGN, SETTING, AND PARTICIPANTS: The assessor-blinded Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial was conducted between October 2015 and April 2019 in 26 European centers...
February 28, 2024: JAMA Cardiology
#8
JOURNAL ARTICLE
Renata Faermann, Miri Sklair-Levy, Anat Shalmon, Osnat Halshtok Neiman, Michael Gotlieb, Yael Yagil, David Samoocha, Shira Galper, Dov Zippel, Tehillah S Menes, Nora Balint-Lahat, Orit Kaidar-Person
AIM: The aim of this study was to evaluate the rate of axillary node positive disease in early breast cancer patients who had a suspicious axillary lymph node on radiation planning CT. METHODS AND MATERIALS: A retrospective review of the medical records of all breast cancer patients who were referred for axillary ultrasound from the radiation unit to the breast imaging unit at the Meirav Breast Center, Sheba Medical Center, during 2012-2022. Ethics approval was obtained...
February 22, 2024: International Journal of Radiation Oncology, Biology, Physics
#9
JOURNAL ARTICLE
Elia Moreno-Cubero, Aljawharah Alrubayyi, Stefan Balint, Ane Ogbe, Upkar S Gill, Rebecca Matthews, Sabine Kinloch, Fiona Burns, Sarah L Rowland-Jones, Persephone Borrow, Anna Schurich, Michael Dustin, Dimitra Peppa
Dynamic regulation of cellular metabolism is important for maintaining homeostasis and can directly influence immune cell function and differentiation, including NK cell responses. Persistent HIV-1 infection leads to a state of chronic immune activation, NK cell subset redistribution, and progressive NK cell dysregulation. In this study, we examined the metabolic processes that characterize NK cell subsets in HIV-1 infection, including adaptive NK cell subpopulations expressing the activating receptor NKG2C, which expand during chronic infection...
January 16, 2024: JCI Insight
#10
Theodora Benedek, Viktoria Wieske, Bálint Szilveszter, Klaus F Kofoed, Patrick Donnelly, José Rodriguez-Palomares, Andrejs Erglis, Josef Veselka, Gintarė Šakalytė, Nada Čemerlić Ađić, Matthias Gutberlet, Ignacio Diez, Gershan Davis, Elke Zimmermann, Cezary Kępka, Radosav Vidakovic, Marco Francone, Małgorzata Ilnicka-Suckiel, Fabian Plank, Juhani Knuuti, Rita Faria, Stephen Schröder, Colin Berry, Luca Saba, Balazs Ruzsics, Nina Rieckmann, Christine Kubiak, Kristian Schultz Hansen, Jacqueline Müller-Nordhorn, Bela Merkely, Per E Sigvardsen, Imre Benedek, Clare Orr, Filipa Xavier Valente, Ligita Zvaigzne, Martin Horváth, Antanas Jankauskas, Filip Ađić, Michael Woinke, Niall Mulvihill, Iñigo Lecumberri, Erica Thwaite, Michael Laule, Mariusz Kruk, Milica Stefanovic, Massimo Mancone, Donata Kuśmierz, Gudrun Feuchtner, Mikko Pietilä, Vasco Gama Ribeiro, Tanja Drosch, Christian Delles, Marco Melis, Michael Fisher, Melinda Boussoussou, Charlotte Kragelund, Rosca Aurelian, Stephanie Kelly, Bruno Garcia Del Blanco, Ainhoa Rubio, Mihály Károlyi, Jens D Hove, Ioana Rodean, Susan Regan, Hug Cuéllar Calabria, László Gellér, Linnea Larsen, Roxana Hodas, Adriane E Napp, Robert Haase, Sarah Feger, Mahmoud Mohamed, Lina M Serna-Higuita, Konrad Neumann, Henryk Dreger, Matthias Rief, John Danesh, Melanie Estrella, Maria Bosserdt, Peter Martus, Jonathan D Dodd, Marc Dewey
In the abstract of the article cited above, the clinical trial number for DISCHARGE (NCT02400229) was inadvertently omitted. The abstract has been revised to include the ClinicalTrials.gov identification. The editors apologize for the error. The online version of the article (https://doi.org/10.2337/dc23-0710) has been updated to correct the error.
February 21, 2024: Diabetes Care
#11
RANDOMIZED CONTROLLED TRIAL
Robert Sykes, Damien Collison, Bela Merkely, Klaus F Kofoed, Patrick Donnelly, José Rodríguez-Palomares, Andrejs Erglis, Josef Veselka, Gintarė Šakalytė, Nada Čemerlić Ađić, Matthias Gutberlet, Jonathan D Dodd, Ignacio Diez, Gershan Davis, Elke Zimmermann, Cezary Kępka, Radosav Vidakovic, Marco Francone, Małgorzata Ilnicka-Suckiel, Fabian Plank, Juhani Knuuti, Rita Faria, Stephen Schröder, Colin Berry, Luca Saba, Balazs Ruzsics, Nina Rieckmann, Christine Kubiak, Kristian Schultz Hansen, Jacqueline Müller-Nordhorn, Pál Maurovich-Horvat, Andreas D Knudsen, Imre Benedek, Clare Orr, Filipa Xavier Valente, Ligita Zvaigzne, Martin Horváth, Antanas Jankauskas, Filip Ađić, Michael Woinke, Stephen Keane, Iñigo Lecumberri, Erica Thwaite, Michael Laule, Mariusz Kruk, Aleksandra Zivanic, Massimo Mancone, Donata Kuśmierz, Gudrun Feuchtner, Mikko Pietilä, Vasco Gama Ribeiro, Tanja Drosch, Christian Delles, Michele Porcu, Michael Fisher, Tamás Bárány, Charlotte Sørum, Rosca Aurelian, Stephanie Kelly, Bruno Garcia Del Blanco, Ainhoa Rubio, Bálint Szilveszter, Jawdat Abdulla, Ioana Rodean, Susan Regan, Hug Cuéllar Calabria, Milán Vecsey-Nagy, Birgit Jurlander, Roxana Hodas, Sarah Feger, Mahmoud Mohamed, Lina M Serna-Higuita, Konrad Neumann, Henryk Dreger, Matthias Rief, Viktoria Wieske, Maros Ferencik, Melanie Estrella, Maria Bosserdt, Peter Martus, Theodora Benedek, Marc Dewey
Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Purpose To compare initial use of CT versus invasive coronary angiography (ICA) on clinical outcomes in patients with stable chest pain stratified by BMI category. Materials and Methods This prospective study represents a prespecified BMI subgroup analysis of the multicenter Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial conducted between October 2015 and April 2019...
February 2024: Radiology
#12
REVIEW
Geraint H Jones, Colin Snodgrass, Cecilia Tubiana, Michael Küppers, Hideyo Kawakita, Luisa M Lara, Jessica Agarwal, Nicolas André, Nicholas Attree, Uli Auster, Stefano Bagnulo, Michele Bannister, Arnaud Beth, Neil Bowles, Andrew Coates, Luigi Colangeli, Carlos Corral van Damme, Vania Da Deppo, Johan De Keyser, Vincenzo Della Corte, Niklas Edberg, Mohamed Ramy El-Maarry, Sara Faggi, Marco Fulle, Ryu Funase, Marina Galand, Charlotte Goetz, Olivier Groussin, Aurélie Guilbert-Lepoutre, Pierre Henri, Satoshi Kasahara, Akos Kereszturi, Mark Kidger, Matthew Knight, Rosita Kokotanekova, Ivana Kolmasova, Konrad Kossacki, Ekkehard Kührt, Yuna Kwon, Fiorangela La Forgia, Anny-Chantal Levasseur-Regourd, Manuela Lippi, Andrea Longobardo, Raphael Marschall, Marek Morawski, Olga Muñoz, Antti Näsilä, Hans Nilsson, Cyrielle Opitom, Mihkel Pajusalu, Antoine Pommerol, Lubomir Prech, Nicola Rando, Francesco Ratti, Hanna Rothkaehl, Alessandra Rotundi, Martin Rubin, Naoya Sakatani, Joan Pau Sánchez, Cyril Simon Wedlund, Anamarija Stankov, Nicolas Thomas, Imre Toth, Geronimo Villanueva, Jean-Baptiste Vincent, Martin Volwerk, Peter Wurz, Arno Wielders, Kazuo Yoshioka, Konrad Aleksiejuk, Fernando Alvarez, Carine Amoros, Shahid Aslam, Barbara Atamaniuk, Jędrzej Baran, Tomasz Barciński, Thomas Beck, Thomas Behnke, Martin Berglund, Ivano Bertini, Marcin Bieda, Piotr Binczyk, Martin-Diego Busch, Andrei Cacovean, Maria Teresa Capria, Chris Carr, José María Castro Marín, Matteo Ceriotti, Paolo Chioetto, Agata Chuchra-Konrad, Lorenzo Cocola, Fabrice Colin, Chiaki Crews, Victoria Cripps, Emanuele Cupido, Alberto Dassatti, Björn J R Davidsson, Thierry De Roche, Jan Deca, Simone Del Togno, Frederik Dhooghe, Kerri Donaldson Hanna, Anders Eriksson, Andrey Fedorov, Estela Fernández-Valenzuela, Stefano Ferretti, Johan Floriot, Fabio Frassetto, Jesper Fredriksson, Philippe Garnier, Dorota Gaweł, Vincent Génot, Thomas Gerber, Karl-Heinz Glassmeier, Mikael Granvik, Benjamin Grison, Herbert Gunell, Tedjani Hachemi, Christian Hagen, Rajkumar Hajra, Yuki Harada, Johann Hasiba, Nico Haslebacher, Miguel Luis Herranz De La Revilla, Daniel Hestroffer, Tilak Hewagama, Carrie Holt, Stubbe Hviid, Iaroslav Iakubivskyi, Laura Inno, Patrick Irwin, Stavro Ivanovski, Jiri Jansky, Irmgard Jernej, Harald Jeszenszky, Jaime Jimenéz, Laurent Jorda, Mihkel Kama, Shingo Kameda, Michael S P Kelley, Kamil Klepacki, Tomáš Kohout, Hirotsugu Kojima, Tomasz Kowalski, Masaki Kuwabara, Michal Ladno, Gunter Laky, Helmut Lammer, Radek Lan, Benoit Lavraud, Monica Lazzarin, Olivier Le Duff, Qiu-Mei Lee, Cezary Lesniak, Zoe Lewis, Zhong-Yi Lin, Tim Lister, Stephen Lowry, Werner Magnes, Johannes Markkanen, Ignacio Martinez Navajas, Zita Martins, Ayako Matsuoka, Barbara Matyjasiak, Christian Mazelle, Elena Mazzotta Epifani, Mirko Meier, Harald Michaelis, Marco Micheli, Alessandra Migliorini, Aude-Lyse Millet, Fernando Moreno, Stefano Mottola, Bruno Moutounaick, Karri Muinonen, Daniel R Müller, Go Murakami, Naofumi Murata, Kamil Myszka, Shintaro Nakajima, Zoltan Nemeth, Artiom Nikolajev, Simone Nordera, Dan Ohlsson, Aire Olesk, Harald Ottacher, Naoya Ozaki, Christophe Oziol, Manish Patel, Aditya Savio Paul, Antti Penttilä, Claudio Pernechele, Joakim Peterson, Enrico Petraglio, Alice Maria Piccirillo, Ferdinand Plaschke, Szymon Polak, Frank Postberg, Herman Proosa, Silvia Protopapa, Walter Puccio, Sylvain Ranvier, Sean Raymond, Ingo Richter, Martin Rieder, Roberto Rigamonti, Irene Ruiz Rodriguez, Ondrej Santolik, Takahiro Sasaki, Rolf Schrödter, Katherine Shirley, Andris Slavinskis, Balint Sodor, Jan Soucek, Peter Stephenson, Linus Stöckli, Paweł Szewczyk, Gabor Troznai, Ludek Uhlir, Naoto Usami, Aris Valavanoglou, Jakub Vaverka, Wei Wang, Xiao-Dong Wang, Gaëtan Wattieaux, Martin Wieser, Sebastian Wolf, Hajime Yano, Ichiro Yoshikawa, Vladimir Zakharov, Tomasz Zawistowski, Paola Zuppella, Giovanna Rinaldi, Hantao Ji
Here we describe the novel, multi-point Comet Interceptor mission. It is dedicated to the exploration of a little-processed long-period comet, possibly entering the inner Solar System for the first time, or to encounter an interstellar object originating at another star. The objectives of the mission are to address the following questions: What are the surface composition, shape, morphology, and structure of the target object? What is the composition of the gas and dust in the coma, its connection to the nucleus, and the nature of its interaction with the solar wind? The mission was proposed to the European Space Agency in 2018, and formally adopted by the agency in June 2022, for launch in 2029 together with the Ariel mission...
2024: Space Science Reviews
#13
JOURNAL ARTICLE
Markus Hecht, Benjamin Frey, Udo S Gaipl, Xie Tianyu, Markus Eckstein, Anna-Jasmina Donaubauer, Gunther Klautke, Thomas Illmer, Maximilian Fleischmann, Simon Laban, Matthias G Hautmann, Bálint Tamaskovics, Thomas B Brunner, Ina Becker, Jian-Guo Zhou, Arndt Hartmann, Rainer Fietkau, Heinrich Iro, Michael Döllinger, Antoniu-Oreste Gostian, Andreas M Kist
PURPOSE: Individual prediction of treatment response is crucial for personalized treatment in multimodal approaches against head-and-neck squamous cell carcinoma (HNSCC). So far, no reliable predictive parameters for treatment schemes containing immunotherapy have been identified. This study aims to predict treatment response to induction chemo-immunotherapy based on the peripheral blood immune status in patients with locally advanced HNSCC. METHODS: The peripheral blood immune phenotype was assessed in whole blood samples in patients treated in the phase II CheckRad-CD8 trial as part of the pre-planned translational research program...
January 16, 2024: Neoplasia: An International Journal for Oncology Research
#14
JOURNAL ARTICLE
Wael Elwasif, William Godoy, Nick Hagerty, J Austin Harris, Oscar Hernandez, Balint Joo, Paul Kent, Damien Lebrun-Grandié, Elijah Maccarthy, Verónica G Melesse Ver-Gara, Bronson Messer, Ross Miller, Sarp Oral, Sergei Bastrakov, Michael Bussmann, Alexander Debus, Klaus Steiniger, Jan Stephan, René Widera, Spencer H Bryngelson, Henry LE Berre, Anand Radhakrishnan, Jeffrey Young, Sunita Chandrasekaran, Florina Ciorba, Osman Simsek, Kate Clark, Filippo Spiga, Jeff Hammond, John E Stone, David Hardy, Sebastian Keller, Jean-Guillaume Piccinali, Christian Trott
This paper assesses and reports the experience of ten teams working to port, validate, and benchmark several High Performance Computing applications on a novel GPU-accelerated Arm testbed system. The testbed consists of eight NVIDIA Arm HPC Developer Kit systems, each one equipped with a server-class Arm CPU from Ampere Computing and two data center GPUs from NVIDIA Corp. The systems are connected together using InfiniBand interconnect. The selected applications and mini-apps are written using several programming languages and use multiple accelerator-based programming models for GPUs such as CUDA, OpenACC, and OpenMP offloading...
February 2023: Proc Int Conf High Perform Comput Asia Pac Reg HPC Asia 2023 Workshops (2023)
#15
JOURNAL ARTICLE
Dorottya Őri, Péter Szocsics, Tamás Molnár, Lucie Bankovska Motlova, Olga Kazakova, Sabrina Mörkl, Michael Wallies, Mohamed Abdulhakim, Sylvie Boivin, Krista Bruna, Carolina Cabaços, Elvira Anna Carbone, Elona Dashi, Giovanni Grech, Stjepan Greguras, Iva Ivanovic, Kaloyan Guevara, Selay Kakar, Konstantinos Kotsis, Ida Maria Ingeholm Klinkby, Jovana Maslak, Shevonne Matheiken, Ana Mirkovic, Nikita Nechepurenko, Angelis Panayi, Ana Telma Pereira, Edith Pomarol-Clotet, Shaeraine Raaj, Polona Rus Prelog, Joan Soler-Vidal, Robertas Strumila, Florian Schuster, Helena Kisand, Ann Reim, Gumru Ahmadova, Matus Vircik, Helin Yilmaz Kafali, Natalia Grinko, Zsuzsa Győrffy, Sándor Rózsa
BACKGROUND: Mental health-related stigma occurs among the public and professionals alike. The lived experience of mental illness has been linked to less stigmatising attitudes. However, data on psychiatrists and the relationship between stigmatising attitudes and psychotherapeutic activity or case discussion groups remains scarce. METHODS: A cross-sectional multicentre study was performed in 32 European countries to investigate the lived experiences and attitudes of psychiatrists toward patients with mental illness as well as the relationship between stigma, psychosocial and professional factors...
December 2023: EClinicalMedicine
#16
JOURNAL ARTICLE
Michael A Silva, Ahmed Abdelsalam, Balint Otvos, Ian Ramsay, Hayes Fountain, Eva Wu, Robert M Starke
Transvenous access is a necessary tool for numerous cerebrovascular pathologies.Transvenous access in the arm offers several benefits compared with transfemoral access, including patient comfort, the avoidance of transfemoral access complications, and the ability to close both radial arterial access and distal arm venous access with a single transradial compression band.1In this video we describe the indications, technical nuances, benefits, and limitations of transvenous access in the arm.neurintsurg;jnis-2023-020996v1/V1F1V1Video 1- Combined venous and arterial access in the arm for treatment of a complex dural arteriovenous fistulaWe present the case of a young patient who presented with pulsatile tinnitus and was found to have a Cognard type IIa dural arteriovenous fistula near the left transverse sigmoid junction...
December 13, 2023: Journal of Neurointerventional Surgery
#17
JOURNAL ARTICLE
Rita Nagy, Klementina Ocskay, Zoltán Sipos, Andrea Szentesi, Áron Vincze, László Czakó, Ferenc Izbéki, Natalia V Shirinskaya, Vladimir L Poluektov, Alexandr N Zolotov, Yin Zhu, Liang Xia, Wenhua He, Robert Sutton, Peter Szatmary, Rajarshi Mukherjee, Isobel Saffron Burridge, Emma Wauchope, Elsa Francisco, David Aparicio, Bruno Pinto, António Gomes, Vitor Nunes, Vasile Marcel Tantau, Emanuela Denisa Sagau, Alina Ioana Tantau, Andra Iulia Suceveanu, Cristina Tocia, Andrei Dumitru, Elizabeth Pando, Piero Alberti, Arturo Cirera, Xavier Molero, Hong Sik Lee, Min Kyu Jung, Eui Joo Kim, Sanghyub Lee, María Lourdes Ruiz Rebollo, Reyes Busta Nistal, Sandra Izquierdo Santervas, Dusan Lesko, Marek Soltes, Jozef Radonak, Hubert Zatorski, Ewa Małecka-Panas, Adam Fabisiak, M Susak Yaroslav, V Maksymenko Mykhailo, A Tkachenko Olekcandr, Giedrius Barauskas, Vytautas Simanaitis, Povilas Ignatavicius, Mariana Jinga, Vasile-Daniel Balaban, Cristina Patoni, Liang Gong, Kai Song, Yunlong Li, T Cúrdia Gonçalves, Marta Freitas, Vítor Macedo, Marlies Vornhuelz, Sarah Klauss, Georg Beyer, Aydin Seref Koksal, Mukaddes Tozlu, Ahmet Tarik Eminler, Nuria Torres Monclús, Eva Pijoan Comas, Juan Armando Rodriguez Oballe, Łukasz Nawacki, Stanisław Głuszek, Alberto Rama-Fernández, Marco Galego, Daniel de la Iglesia, Umut Emre Aykut, Deniz Güney Duman, Rahmi Aslan, Adriana Gherbon, Lihui Deng, Wei Huang, Qing Xia, Goran Poropat, Anja Radovan, Luka Vranić, Claudio Ricci, Carlo Ingaldi, Riccardo Casadei, Ionut Negoi, Cezar Ciubotaru, Florin Mihail Iordache, Gabriel Constantinescu, Vasile Sandru, Engin Altintas, Hatice Rizaoglu Balci, Júlio Constantino, Débora Aveiro, Jorge Pereira, Suleyman Gunay, Seda Misirlioglu Sucan, Oleksiy Dronov, Inna Kovalska, Nikhil Bush, Surinder Singh Rana, Serge Chooklin, Serhii Chuklin, Ionut Adrian Saizu, Cristian Gheorghe, Philipp Göltl, Michael Hirth, Radu Bogdan Mateescu, Geanina Papuc, Georgi Angelov Minkov, Emil Tihomirov Enchev, Laura Mastrangelo, Elio Jovine, Weiwei Chen, Quping Zhu, Anita Gąsiorowska, Natalia Fabisiak, Mihailo Bezmarevic, Andrey Litvin, Martina Cattani Mottes, Eun Kwang Choi, Peter Bánovčin, Lenka Nosáková, Mila Dimitrova Kovacheva-Slavova, Ali Kchaou, Ahmed Tlili, Marco V Marino, Katarzyna Kusnierz, Artautas Mickevicius, Marcus Hollenbach, Pavol Molcan, Orestis Ioannidis, Mark Valerievich Tokarev, Ali Tüzün Ince, Ivan Albertovich Semenenko, Shamil Galeev, Elena Ramírez-Maldonado, Ville Sallinen, Petr Pencik, Judit Bajor, Patricia Sarlós, Roland Hágendorn, Szilárd Gódi, Imre Szabó, József Czimmer, Gabriella Pár, Anita Illés, Nándor Faluhelyi, Péter Kanizsai, Tamás Nagy, Alexandra Mikó, Balázs Németh, József Hamvas, Barnabás Bod, Márta Varga, Imola Török, János Novák, Árpád Patai, János Sümegi, Csaba Góg, Mária Papp, Bálint Erőss, Szilárd Váncsa, Brigitta Teutsch, Katalin Márta, Péter Jenő Hegyi, Tamás Tornai, Balázs Lázár, Tamás Hussein, Dorottya Tarján, Mónika Lipp, Beáta Kovács, Orsolya Urbán, Emese Fürst, Edina Tari, Ibolya Kocsis, Pál Maurovich-Horvát, Balázs Tihanyi, Orsolya Eperjesi, Zita Kormos, Pál Ákos Deák, Andrea Párniczky, Péter Hegyi
There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol...
December 13, 2023: Scientific Reports
#18
JOURNAL ARTICLE
Daniel Reumann, Christian Krauditsch, Maria Novatchkova, Edoardo Sozzi, Sakurako Nagumo Wong, Michael Zabolocki, Marthe Priouret, Balint Doleschall, Kaja I Ritzau-Reid, Marielle Piber, Ilaria Morassut, Charles Fieseler, Alessandro Fiorenzano, Molly M Stevens, Manuel Zimmer, Cedric Bardy, Malin Parmar, Jürgen A Knoblich
Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are involved in movement control and reward-related cognition. In Parkinson's disease, nigrostriatal midbrain dopaminergic neurons degenerate and cause typical Parkinson's disease motor-related impairments, while the dysfunction of mesocorticolimbic midbrain dopaminergic neurons is implicated in addiction and neuropsychiatric disorders. Study of the development and selective neurodegeneration of the human dopaminergic system, however, has been limited due to the lack of an appropriate model and access to human material...
December 2023: Nature Methods
#19
JOURNAL ARTICLE
Natalie Patel, Daniel A Leffler, Abdulbaqi Al-Toma, Chris J Mulder, Luca Elli, Geliang Gan, Pallavi Patil, Amporn Atsawarungruangkit, Karel C Kuijpers, Alessandro Del Gobbo, Jeffrey Goldsmith, Zach Hintze, M Cristina Pacheco, Michael Vieth, Balint Melcher, Marcela Salomao, Rish Pai, John Hart, Andrea Olivas, Bita Naini, Cherise Meyerson, Won-Tak Choi, Sanjay Kakar, Maria Westerhoff, Jerome Cheng, Purva Gopal, Suntrea Hammer, Mariana Moreno Prats, Mary P Bronner, Marie E Robert
Validated nonbiopsy methods to assure duodenal mucosal healing in celiac disease are lacking, yet ongoing mucosal injury is associated with anemia, osteoporosis, and lymphoma. Most providers utilize clinical data as surrogates of mucosal status to avoid additional esophagogastroduodenoscopy. The reliability of such surrogates to predict mucosal recovery has been incompletely evaluated. The aim of this study was to rigorously assess patterns of histologic mucosal recovery at follow-up in celiac disease and to correlate findings with clinical data...
February 1, 2024: American Journal of Surgical Pathology
#20
Andrew Gonzalez, Petteri Vihervaara, Patricia Balvanera, Amanda E Bates, Elisa Bayraktarov, Peter J Bellingham, Andreas Bruder, Jillian Campbell, Michael D Catchen, Jeannine Cavender-Bares, Jonathan Chase, Nicholas Coops, Mark J Costello, Bálint Czúcz, Aurélie Delavaud, Maria Dornelas, Grégoire Dubois, Emmett J Duffy, Hilde Eggermont, Miguel Fernandez, Nestor Fernandez, Simon Ferrier, Gary N Geller, Michael Gill, Dominique Gravel, Carlos A Guerra, Robert Guralnick, Michael Harfoot, Tim Hirsch, Sean Hoban, Alice C Hughes, Wim Hugo, Margaret E Hunter, Forest Isbell, Walter Jetz, Norbert Juergens, W Daniel Kissling, Cornelia B Krug, Peter Kullberg, Yvan Le Bras, Brian Leung, Maria Cecilia Londoño-Murcia, Jean-Michel Lord, Michel Loreau, Amy Luers, Keping Ma, Anna J MacDonald, Joachim Maes, Melodie McGeoch, Jean Baptiste Mihoub, Katie L Millette, Zsolt Molnar, Enrique Montes, Akira S Mori, Frank E Muller-Karger, Hiroyuki Muraoka, Masahiro Nakaoka, Laetitia Navarro, Tim Newbold, Aidin Niamir, David Obura, Mary O'Connor, Marc Paganini, Dominique Pelletier, Henrique Pereira, Timothée Poisot, Laura J Pollock, Andy Purvis, Adriana Radulovici, Duccio Rocchini, Claudia Roeoesli, Michael Schaepman, Gabriela Schaepman-Strub, Dirk S Schmeller, Ute Schmiedel, Fabian D Schneider, Mangal Man Shakya, Andrew Skidmore, Andrew L Skowno, Yayioi Takeuchi, Mao-Ning Tuanmu, Eren Turak, Woody Turner, Mark C Urban, Nicolás Urbina-Cardona, Ruben Valbuena, Anton Van de Putte, Basile van Havre, Vladimir Ruslan Wingate, Elaine Wright, Carlos Zambrana Torrelio
No abstract text is available yet for this article.
November 20, 2023: Nature Ecology & Evolution
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