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https://www.readbyqxmd.com/read/27920849/subcapsular-hepatic-endometriosis-case-report-and-review-of-the-literature
#1
Ahmed Monier Sherif, Eman Rashid Musa, Rajendra Kedar, Liying Fu
Hepatic endometriosis is a very rare medical condition characterized by the implantation of ectopic endometrial tissue within the hepatic parenchyma. Preoperative diagnosis is difficult via cross-sectional imaging and histopathologic evaluation remains the gold standard for diagnosis. We report a case of hepatic endometrioma in a 44-year-old woman with history of endometriosis. The literature is reviewed, and magnetic resonance imaging findings together with differential diagnosis of hepatic endometriosis are highlighted...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27895787/runx2-expression-a-mesenchymal-stem-marker-for-cancer
#2
Maria Teresa Valenti, Paola Serafini, Giulio Innamorati, Anna Gili, Samuele Cheri, Claudio Bassi, Luca Dalle Carbonare
The transcription factor runt-related transcription factor 2 (Runx2) is a master gene implicated in the osteogenic differentiation of mesenchymal stem cells, and thus serves a determinant function in bone remodelling and skeletal integrity. Various signalling pathways regulate Runx2 abundance, which requires a number of molecules to finely modulate its expression. Furthermore, this gene may be ectopically-expressed in cancer cells. Recent studies have reported the involvement of Runx2 in cell proliferation, epithelial-mesenchymal transition, apoptosis and metastatic processes, suggesting it may represent a useful therapeutic target in cancer treatment...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27891779/using-insurance-claims-data-to-identify-and-estimate-critical-periods-in-pregnancy-an-application-to-antidepressants
#3
Elizabeth C Ailes, Regina M Simeone, April L Dawson, Emily E Petersen, Suzanne M Gilboa
BACKGROUND: Health insurance claims are a rich data source to examine medication use in pregnancy. Our objective was to identify pregnant women, their pregnancy outcomes, and date of their last menstrual period (LMP), and to estimate antidepressant dispensations in pregnancy. METHODS: From a literature search, we identified diagnosis and procedure codes indicating the end of a pregnancy. Using Truven Health MarketScan(®) Commercial Claims and Encounters Databases, we identified all inpatient admissions and outpatient service claims with these codes...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27888831/-extranasal-glioma-surgery-in-a-newborn-a-case-report
#4
Emel Cadallı Tatar, Gökçe Aksoy Yıldırım, Kemal Keseroğlu, Ali Özdek, Güleser Saylam, Mehmet Hakan Korkmaz, Reyhan Polat
Nasal gliomas are rarely seen, congenital, benign and nonhereditary lesions. These are not true tumors that occur due to extradural malposition of ectopic glial tissue during embryologic development. These are generally diagnosed during childbirth and may have an intracranial extension with fibrous stalk. Treatment of these masses that cause nasal obstruction and cosmetic deformity according to location, is total excision. In this case report, we present an extranasal glioma case whose surgery was done when she was 11 days old...
September 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27882303/ovarian-like-differentiation-in-eutopic-and-ectopic-endometrioses-with-aberrant-fsh-receptor-insl3-and-gata4-6-expression
#5
Baptiste Fouquet, Pietro Santulli, Jean-Christophe Noel, Micheline Misrahi
Endometriosis, the hormone-dependent extrauterine dissemination of endometrial tissue outside the uterus, affects 5-15% of women of reproductive age. Pathogenesis remains poorly understood as well as the estrogen production by endometriotic tissue yielding autocrine growth. Estrogens (E2) are normally produced by the ovaries. We investigated whether aberrant "ovarian-like" differentiation occurred in endometriosis. 69 women, with (n = 38) and without (n = 31) histologically proven endometriosis were recruited...
December 2016: BBA Clinical
https://www.readbyqxmd.com/read/27866035/a-unique-presentation-of-ectopic-thyroid-a-case-report
#6
Erika Allen, Masoud Alzeerah, Stevenson Tsiao, Nail Aydin, Subhasis Misra
INTRODUCTION: This case presents a painful ectopic thyroid, an unusual presentation, in an atypical location. The patient's history of an ingested fish bone, her acute presentation, and inconclusive imaging, made this case a diagnostic dilemma. PRESENTATION OF CASE: 61-year-old female presented with acutely worsening history of left throat pain and dysphagia after swallowing a fish bone. CT scan showed a foreign body in the anterior wall of the cervical esophagus...
November 3, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27824968/an-intrapericardial-ectopic-thyroid-mimicking-metastasis-in-a-patient-with-papillary-thyroid-cancer-localization-differential-diagnosis-by-18-f-fdg-pet-ct-and-ablation-by-131-i
#7
Seol Hoon Park, Minjung Seo, Tae Young Park, Seong Nam-Goong
We report a very rare case of incidental intrapericardial thyroid in a papillary thyroid cancer patient. Post ablation scan revealed iodine-131 ((131)I) uptake in the mid-chest. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) was performed and showed a (18)F-FDG avid lesion between the right atrium and the ascending aorta, (which was) shown tube an ectopic thyroid and not metastasis. The lesion disappeared on a 6 month follow-up (123)I whole body scan while serum thyroglobulin was negative...
November 8, 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27797069/igg4-related-sclerosing-mesenteritis-causing-bowel-obstruction-a-case-report
#8
Atsushi Abe, Tatsuya Manabe, Nobuyoshi Takizawa, Takashi Ueki, Daisuke Yamada, Kinuko Nagayoshi, Yoshihiko Sadakari, Hayato Fujita, Shuntaro Nagai, Hidetaka Yamamoto, Yoshinao Oda, Masafumi Nakamura
Sclerosing mesenteritis (SM) is a rare inflammatory and fibrosing disease primarily involving the small-bowel mesentery. Recently, SM was reported to be closely related to IgG4-related disease (IgG4-RD). This report describes a patient with SM associated with IgG4-RD. A 77-year-old woman with a history of surgery for ectopic pregnancy and wound dehiscence presented with intestinal obstruction. Abdominal enhanced computed tomography (CT) revealed an enhanced, radially shaped, oval mass, 3 cm in diameter, with an unclear rim in the mesentery of the distal ileum, which may have involved the distal ileum...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27766445/cystic-parathyroid-glands-in-men1-a-rare-entity
#9
Tiziana Cavalli, Francesco Giudici, Gabriella Nesi, Andrea Amorosi, Raffaella Santi, Maria Luisa Brandi, Francesco Tonelli
Approximately 300 cases of sporadic parathyroid cyst (PCs) have been reported to date. Only two cases have been described in MEN1 so far. Detection by imaging could be challenging, especially in multiglandular primary hyperparathyroidism (HPT) and clinical outcome could be different. During the period 1990-2014, 71 MEN1 patients were operated for primary hyperparathyroidism in our centre. We report three cases of PCs in MEN1 patients affected by HPT, who underwent a total or subtotal parathyroidectomy with transcervical thymectomy...
October 20, 2016: Familial Cancer
https://www.readbyqxmd.com/read/27766107/case-report-recurrent-abdominal-symptoms-in-a-child-with-panhypopituitarism-there-is-always-a-differential
#10
Laura Olbrich, Eva Schmidt, Ertan Mayatepek, Markus Vogel
BACKGROUND: We report the case of a 6 year old boy suffering from adenohypophysis aplasia as well as ectopic neurohypophysis and delayed diagnosis of familial Mediterranean fever (FMF). CASE PRESENTATION: The boy was diagnosed with panhypopituitarism during the neonatal period and suffered from recurrent episodes during the following years suggesting infections. He also showed signs of adrenal insufficiency. Finally, at the age of 6 years, an additional diagnosis of familial Mediterranean fever (FMF) was clinically suspected and later confirmed by molecular analysis...
2016: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/27760899/small-nonfunctional-parathyroid-cysts-single-institution-experience
#11
Ljubica Fustar Preradovic, Davorin Danic, Radan Dzodic
Parathyroid cysts (PCs) account for less than 1% of all parathyroid lesions and are most commonly located along thyroid lobes, rarely at ectopic sites. PCs are important because they can pose a differential diagnostic challenge against other cystic formations of the neck. PCs can be functional (elevated serum parathyroid hormone level) and nonfunctional. Four cases of nonfunctional PCs are presented. All four female patients underwent physical examination and ultrasonography of the neck with ultrasound-guided fine-needle aspiration biopsy (UG-FNA)...
October 19, 2016: Endocrine Journal
https://www.readbyqxmd.com/read/27746436/metastatic-pancreatic-neuroendocrine-tumor-that-progressed-to-ectopic-adrenocorticotropic-hormone-acth-syndrome-with-growth-hormone-releasing-hormone-ghrh-production
#12
Rie Tadokoro, Shotaro Sato, Fumiko Otsuka, Makoto Ueno, Shinichi Ohkawa, Hideki Katakami, Matsuo Taniyama, Shoichiro Nagasaka
The patient was a 61-year-old woman who had a well-differentiated pancreatic neuroendocrine tumor (PNET) with lymph node metastasis. After 15 months of octreotide treatment, glucose control deteriorated and pigmentation of the tongue and moon face developed, leading to the diagnosis of ectopic adrenocorticotropic hormone (ACTH) syndrome. An abnormal secretion of growth hormone (GH) was identified, and the plasma growth hormone-releasing hormone (GHRH) level was elevated. A tumor biopsy specimen positively immunostained for ACTH and GHRH...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27709473/multiparametric-ultrasonography-and-ultrasound-elastography-in-the-differentiation-of-parathyroid-lesions-from-ectopic-thyroid-lesions-or-lymphadenopathies
#13
Andrea M Isidori, Vito Cantisani, Elisa Giannetta, Daniele Diacinti, Emanuele David, Valerio Forte, Daniela Elia, Corrado De Vito, Emilia Sbardella, Daniele Gianfrilli, Francesco Monteleone, Jessica Pepe, Salvatore Minisola, Giorgio Ascenti, Vito D'Andrea, Carlo Catalano, Ferdinando D'Ambrosio
To evaluate the accuracy of ultrasound elastography with Elastoscan(TM) Core Index in the differential diagnosis of parathyroid lesions from ectopic thyroid nodules and lymph nodes. Seventy nine patients with repeatedly high levels of circulating intact parathyroid hormone, normal vitamin D and renal function tests, with an ultrasound scan showing a neck lesion, sharply demarcated from the thyroid lobules, were consecutively enrolled. Ultrasound with and without Color Doppler and ultrasound elastography were performed before histological examination...
October 5, 2016: Endocrine
https://www.readbyqxmd.com/read/27679689/imaging-and-clinical-data-of-placental-site-trophoblastic-tumor-a-case-report
#14
Maryam Niknejadi, Firoozeh Ahmadi, Farnaz Akhbari
Placental site trophoblastic tumor (PSTT) is a very rare variant of gestational trophoblastic tumor. It can occur after normal termination of pregnancy or spontaneous abortion and ectopic or molar pregnancy. There is a wide range of clinical manifestations from a benign condition to an aggressive disease with fatal outcome. One of the most important characteristics of PSTT, unlike other forms of gestational trophoblastic diseases (GTD) is the presence of low beta-subunit of human chorionic gonadotropin (β-hCG) levels because it is a neoplastic proliferation of intermediate trophoblastic cells...
April 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27672644/cystic-jejunal-duplication-with-heinrich-s-type-i-ectopic-pancreas-incidentally-discovered-in-a-patient-with-pancreatic-tail-neoplasm
#15
Simona Gurzu, Tivadar Bara, Tivadar Bara, Annamaria Fetyko, Ioan Jung
The aim of this study was to present a case of enteric duplication cyst and criteria for a proper differential diagnosis. A 51-year-old male was hospitalized for pancreatic tail neoplasm and distal pancreatectomy with splenectomy was performed. During surgery, a jejunal cystic lesion was incidentally detected and jejunectomy was performed. Microscopically, the cyst was observed to be covered by Keratin 7/Keratin 20 positive intestinal type epithelium and the muscularis layer was shared by the cyst and adjacent jejunum, without a cleavage plane between the cyst wall and jejunal muscularis propria...
September 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27646971/mdct-of-pelvic-inflammatory-disease-a-review-of-the-pathophysiology-gamut-of-imaging-findings-and-treatment
#16
James Spain, Matthew Rheinboldt
Representing an ascending, sexually spread pyogenic infection of the female genital tract, pelvic inflammatory disease (PID) is a commonly encountered cause for emergency visits and hospitalizations among young and adult female patients. Though gynecologic evaluation and sonography constitute the mainstay of diagnosis, multidetector CT imaging of the abdomen and pelvis is not uncommonly performed, often as the initial imaging modality, due to the frequently vague and indeterminate clinical presentation. As such, knowledge and attenuation to the often subtle early imaging features of PID afford the radiologist a critical chance to direct and expedite appropriate pathways of patient care, minimizing the risk for secondary complications, including infertility, ectopic pregnancy, and enteric adhesions...
September 19, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27603409/out-of-third-ventricle-colloid-cysts-review-of-the-literature-on-pathophysiology-diagnosis-and-treatment-of-an-uncommon-condition-with-a-focus-on-headache
#17
Giuseppe M Barbagallo, Giuseppe Raudino, Massimiliano Visocchi, Massimiliano Maione, Francesco Certo
BACKGROUND: Colloid cysts are rare benign intracranial lesions classically described as "third ventricle colloid cysts" because of their location within the third ventricle. These lesions' clinical and diagnostic features are mainly related to intermittent or persistent obstruction of foramina of Monro causing cerebro-spinal fluid (CSF) circulation impairment and symptoms of raised intracranial pressure. Few reports on colloid cysts located outside the third ventricle have been published over the years...
September 7, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27579413/intrarenal-adrenocortical-adenoma-treated-by-robotic-partial-nephrectomy-with-adrenalectomy
#18
Samay Sappal, Jay Sulek, Steven C Smith, Lance J Hampton
BACKGROUND: We present an intrarenal adrenocortical adenoma discovered incidentally after robot-assisted partial nephrectomy and total adrenalectomy for a suspicious renal mass. Current literature describes the rare occurrence of an adrenocortical adenoma arising from a renal-adrenal fusion. This case represents an uncommon, benign pathology that should be considered in the differential diagnosis of an enhancing renal mass. CASE PRESENTATION: The patient is a 62-year-old female found to have an enhancing mass at the anterolateral aspect of the upper pole of the right kidney concerning for renal-cell carcinoma...
2016: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/27533743/an-ectopically-expressed-serum-mirna-signature-is-prognostic-diagnostic-and-biologically-related-to-liver-allograft-rejection
#19
Abraham Shaked, Bao-Li Chang, Michael R Barnes, Peter Sayre, Yun R Li, Smita Asare, Michele DesMarais, Michael V Holmes, Toumy Guettouche, Brendan J Keating
: The ability to noninvasively diagnose acute cellular rejection (ACR) with high specificity and sensitivity would significantly advance personalized liver transplant recipient care and management of immunosuppression. We performed microRNA (miRNA) profiling in 318 serum samples from 69 liver transplant recipients enrolled in the Immune Tolerance Network immunosuppression withdrawal (ITN030ST) and Clinical Trials in Organ Transplantation (CTOT-03) studies. We quantified serum miRNA at clinically indicated and/or protocol biopsy events (n = 130)...
August 17, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/27476254/-multidose-treatment-of-methotrexate-in-cornual-ectopic-pregnancy
#20
M Pantoja Garrido, M N Cabezas-Palacios, S Tato-Varela
BACKROUND: Ectopic pregnancy represents a common entity when the differential diagnosis of first trimester pathologies is performed. Extratubal location, nonetheless, is an in unfrequent situation that delays and difficults the diagnoses. CASE REPORT: 41-year-old women who goes to clinic for a pregnancy test, which proved positive done. During normal ultrasonographic we observed attached with endometrial 8 mm thick, without gestational sac inside, no free liquid in the bottom of the pouch of Douglas...
May 2016: Ginecología y Obstetricia de México
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