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https://www.readbyqxmd.com/read/28226302/towards-a-theoretical-model-on-medicines-as-a-health-need
#1
Claudia Marcela Vargas-Peláez, Luciano Soares, Marina Raijche Mattozo Rover, Carine Raquel Blatt, Aukje Mantel-Teeuwisse, Francisco Augusto Rossi Buenaventura, Luis Guillermo Restrepo, María Cristina Latorre, José Julián López, María Teresa Bürgin, Consuelo Silva, Silvana Nair Leite, Farias Mareni Rocha
Medicines are considered one of the main tools of western medicine to resolve health problems. Currently, medicines represent an important share of the countries' healthcare budget. In the Latin America region, access to essential medicines is still a challenge, although countries have established some measures in the last years in order to guarantee equitable access to medicines. A theoretical model is proposed for analysing the social, political, and economic factors that modulate the role of medicines as a health need and their influence on the accessibility and access to medicines...
February 15, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28224371/can-disproportionality-analysis-of-post-marketing-case-reports-be-used-for-comparison-of-drug-safety-profiles
#2
Christiane Michel, Emil Scosyrev, Michael Petrin, Robert Schmouder
Clinical trials usually do not have the power to detect rare adverse drug reactions. Spontaneous adverse reaction reports as for example available in post-marketing safety databases such as the FDA Adverse Event Reporting System (FAERS) are therefore a valuable source of information to detect new safety signals early. To screen such large data-volumes for safety signals, data-mining algorithms based on the concept of disproportionality have been developed. Because disproportionality analysis is based on spontaneous reports submitted for a large number of drugs and adverse event types, one might consider using these data to compare safety profiles across drugs...
February 21, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28221676/key-factors-that-influence-government-policies-and-decision-making-about-healthcare-priorities-lessons-for-the-field-of-eating-disorders
#3
Harvey Whiteford, Ruth Striegel Weissman
Worldwide, the demand for healthcare exceeds what individuals and governments are able to afford. Priority setting is therefore inevitable, and mental health services have often been given low priority in the decision-making process. Drawing on established economic criteria, and specifically the work of Philip Musgrove, key factors which influence government decision-making about health priorities are reviewed. These factors include the size of the health burden, the availability of cost-effective interventions to reduce the burden, whether private markets can provide the necessary treatment efficiently, whether there are "catastrophic costs" incurred in accessing treatment, whether negative externalities arise from not providing care, and if the "rule of rescue" applies...
February 21, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28220213/labour-market-marginalisation-subsequent-to-suicide-attempt-in-young-migrants-and-native-swedes
#4
T Niederkrotenthaler, M Wang, M Helgesson, H Wilcox, M Gould, E Mittendorfer-Rutz
PURPOSE: This study aimed to compare young individuals who differed in terms of birth region and history of suicide attempt regarding socio-demographic and healthcare factors, and with regard to their risks of subsequent unemployment, sickness absence and disability pension. METHODS: Prospective cohort study based on register linkage of 2,801,558 Swedish residents, aged 16-40 years in 2004, without disability pension and with known birth country, followed up 2005-2011...
February 20, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28219376/cooperate-a-paradigm-shift-for-health-equity
#5
REVIEW
Wei-Ching Chang, Joy H Fraser
The role of competition and cooperation in relation to the goal of health equity is examined in this paper. The authors explain why the win-lose mentality associated with avoidable competition is ethically questionable and less effective than cooperation in achieving positive outcomes, particularly as it relates to health and health equity. Competition, which differentiates winners from losers, often with the winner-takes-all reward system, inevitably leads to a few winners and many losers, resulting in social inequality, which, in turn, engenders and perpetuates health inequity...
February 21, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28217446/the-dangers-of-sexual-enhancement-supplements-and-counterfeit-drugs-to-treat-erectile-dysfunction
#6
REVIEW
Jason Chiang, Faysal A Yafi, Philip J Dorsey, Wayne J G Hellstrom
Counterfeit phosphodiesterase-5 inhibitors (PDE-5i) are an increasing problem. Already in widespread use, the market for PDE-5i is steadily growing as the population ages. Counterfeiters are taking advantage of this growing market by developing illicit and counterfeit PDE-5i products. Many factors are contributing to the rapid growth of the illicit market, such as the low risk of prosecution, potentially high financial reward, and ease of distribution via Internet pharmacies. Consumers of illicit PDE-5i often do not realize they are using counterfeit products and placing themselves at an unnecessary health risk...
February 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28212687/balancing-the-health-workforce-breaking-down-overall-technical-change-into-factor-technical-change-for-labour-an-empirical-application-to-the-dutch-hospital-industry
#7
Jos L T Blank, Bart L van Hulst
BACKGROUND: Well-trained, well-distributed and productive health workers are crucial for access to high-quality, cost-effective healthcare. Because neither a shortage nor a surplus of health workers is wanted, policymakers use workforce planning models to get information on future labour markets and adjust policies accordingly. A neglected topic of workforce planning models is productivity growth, which has an effect on future demand for labour. However, calculating productivity growth for specific types of input is not as straightforward as it seems...
February 17, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28210864/pharmacy-benefit-management-companies-do-they-create-value-in-the-us-healthcare-system
#8
Alan Lyles
Pharmacy benefit management companies (PBMs) perform functions in the US market-based healthcare system that may be performed by public agencies or quasi-public institutions in other nations. By aggregating lives covered under their many individual contracts with payers, PBMs have formidable negotiating power. They influence pharmaceutical insurance coverage, design the terms of coverage in a plan's drug benefit, and create competition among providers for inclusion in a plan's network. PBMs have, through intermediation, the potential to secure lower drug prices and to improve rational prescribing...
February 16, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28202801/molecular-epidemiology-and-strain-comparison-between-hepatitis-e-virus-in-human-sera-and-pig-livers-during-2014-2016-in-hong-kong
#9
Martin C W Chan, Kirsty Kwok, Tin-Nok Hung, Paul K S Chan
Hepatitis E virus (HEV) causes substantial morbidity and mortality in developing countries and is considered an emerging food-borne pathogen in previously non-endemic developed countries. To investigate genetic association between human HEV infection and HEV-contaminated high-risk food in Hong Kong, we compared local virus strains obtained from hepatitis E patient sera with those surveyed from high-risk food items during 2014-2016. Twenty-four cases of laboratory-confirmed human HEV infections were identified from January 2014 to March 2016 in our hospitals...
February 15, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28199277/funding-accountable-care-in-oregon-financial-models-in-two-coordinated-care-organizations
#10
Lauren Broffman, Kristin Brown, Bruce K Bayley, Lucy Savitz, Jill Rissi
Oregon's coordinated care organizations (CCOs) are an integral part of a massive statewide reform that brings accountable care to Medicaid. CCOs are regional collaboratives among health plans, providers, county public health, and communitybased organizations that administer a single global budget covering physical, mental, and dental healthcare for low-income Oregonians. CCOs have been given freedom within the global budget to implement reforms that might capture efficiencies in cost and quality. For this study-fielded between 2012 and 2015-we traced the path of the global budget through the interior structures of two of Oregon's most promising CCOs...
July 2016: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28199180/marketing-authorization-procedures-for-advanced-cancer-drugs
#11
Christel Protière, Rachel Baker, Dominique Genre, Anthony Goncalves, Patrice Viens
BACKGROUND: The past decades have seen advances in cancer treatments in terms of toxicity and side effects but progress in the treatment of advanced cancer has been modest. New drugs have emerged improving progression free survival but with little impact on overall survival, raising questions about the criteria on which to base decisions to grant marketing authorizations and about the authorization procedure itself. For decisions to be fair, transparent and accountable, it is necessary to consider the views of those with relevant expertise and experience...
February 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28197738/vaccines-for-staphylococcus-aureus-and-target-populations
#12
Clarissa Pozzi, Reuben Olaniyi, Lassi Liljeroos, Ilaria Galgani, Rino Rappuoli, Fabio Bagnoli
Staphylococcus aureus is a leading pathogen in surgical site, intensive care unit, and skin infections, as well as healthcare-associated pneumonias. These infections are associated with an enormous burden of morbidity, mortality, and increase of hospital length of stay and patient cost. S. aureus is impressively fast in acquiring antibiotic resistance, and multidrug-resistant strains are a serious threat to human health. Due to resistance or insufficient effectiveness, antibiotics and bundle measures leave a tremendous unmet medical need worldwide...
February 15, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28190508/navigating-the-clinical-trial-pathway-conception-design-execution-and-results-dissemination
#13
John S Sampalis, Joanne Watson, Stella Boukas, Marianna Boukas, Natalie Harvey, Sanjay Machado, Michel Bordeleau, Emmanouil Rampakakis
Dr Sampalis is founder, Chief Executive Officer, and Chief Scientific Officer of JSS Medical Research Inc, founded in 1997. He is a tenured professor of Surgery and Epidemiology & Biostatistics of McGill University, the University of Montreal and University of Laval. Recognized as a leading clinical epidemiologist and one of the top trauma researchers in Canada, he possesses extensive expertise in health services research, clinical trials, and offers services as a Research and Epidemiological Consultant for numerous pharmaceutical companies, hospitals and government organizations and agencies...
March 2017: Surgery
https://www.readbyqxmd.com/read/28190507/best-practices-in-early-phase-medical-device-development-engineering-prototyping-and-the-beginnings-of-a-quality-management-system
#14
Kristy Fearis, Aidan Petrie
Kristy Fearis is the founder and president of KPConsulting. She has held various positions in the medical device and research industry. She has led programs for medical industry leaders Medtronic, Edward Lifesciences, and Kimberly-Clark Healthcare to develop and commercialize Class II and III devices. Although a true quality management systems specialist at heart, Kristy has a passion for effectively and efficiently applying quality systems principles to early stage development to maximize benefit while minimizing impact on resources and time to market...
March 2017: Surgery
https://www.readbyqxmd.com/read/28187906/narrating-health-and-scarcity-guyanese-healthcare-workers-development-reformers-and-sacrifice-as-solution-from-socialist-to-neoliberal-governance
#15
Alexis Walker
In oral history interviews, Guyanese healthcare workers emphasize continuity in public health governance throughout the late twentieth century, despite major shifts in broader systems of governance during this period. I argue that these healthcare workers' recollections reflect long-term scarcities and the discourses through which both socialist politicians and neoliberal reformers have narrated them. I highlight the striking similarities in discourses of responsibility and efficiency advanced by socialist politicians in 1970s Guyana and by World Bank representatives designing the country's market transition in the late 1980s, and the ways these discourses have played out in Guyana's health system...
February 1, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28186053/aim-agile-instrumented-monitoring-for-improving-user-experience-of-participation-in-healthit-development
#16
Janne Pitkänen, Marko Nieminen
Participation of healthcare professionals in information technology development has emerged as an important challenge. As end-users, the professionals are willing to participate in the development activities, but their experiences on the current methods of participation remain mostly negative. There is lack of applicable methods for meeting the needs of agile development approach and scaling up to the largest implementation projects, while maintaining the interest of the professional users to participate in development activities and keeping up their ability to continue working in a productive manner...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28185683/suicidal-behaviours-in-male-and-female-users-of-illicit-drugs-recruited-in-drug-treatment-facilities
#17
Elisabet Arribas-Ibar, Josep Maria Suelves, Albert Sanchez-Niubò, Antònia Domingo-Salvany, M T Brugal
OBJECTIVE: We assessed prevalence of suicidal ideation and plans among illicit drug users and their association with contextual factors, by gender. METHODS: Cross-sectional study. In a sample of 511 illicit drug users recruited during spring 2012 in drug treatment and prevention facilities in Catalonia (Spain), the prevalence of suicidal ideation/plans in the last 12 months was assessed. Poisson regression was used to examine associations between suicidal ideation/plans and various factors (socio-demographic, psychological, illegal drug market activities and marginal income generation activities, which included any reported sex work, stealing, peddling, begging or borrowing on credit from a dealer)...
February 6, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28183411/funding-of-graduate-medical-education-in-a-market-based-healthcare-system
#18
Barbara L Schuster
The graduate medical education (GME) process in the United States is considered the most respected model for high-quality education of graduate physicians in the world. With substantial funding through government and private insurers and through structured educational accreditation standards, the American Board of Medical Specialists-certified physicians are recognized for their expertise in delivering high-quality medical care. However, under fiscal constraints and changing social expectations, questions are continually posed about the process of funding and whether the "physician outcomes" are sufficient to continue with the investment...
February 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28181159/an-assessment-of-romani-women-s-autonomy-and-timing-of-pregnancy-in-serbia-and-macedonia
#19
Kristefer Stojanovski, Teresa Janevic, Blasko Kasapinov, Zeljka Stamenkovic, Janko Jankovic
Background Roma are Europe's largest minority population. Serbia and Macedonia have the greatest proportion of Roma outside of the European Union. Our objective was to examine women's agency and how it related to desired timing of pregnancy among Romani women in Macedonia and Serbia. Methods We surveyed 410 Romani women who had given birth in the last 2 years between November 2012-February 2013 in Serbia and Macedonia using purposeful snowball sampling. Log-Poisson models were used to examine the association between women's inclusion in healthcare decision- making and desired timing of pregnancy...
February 8, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28173802/malaria-from-hyperendemicity-to-elimination-in-hekou-county-on-china-vietnam-border-an-ecological-study
#20
Jian-Wei Xu, Jian-Jie Li, Hong-Ping Guo, Shu-Wei Pu, Shu-Mei Li, Rong-Hua Wang, Hui Liu, Wei-Jia Wang
BACKGROUND: Malaria control and elimination are challenged by diversity and complexity of the determinants on the international border in the Great Mekong Sub-region. Hekou, a Chinese county on the China-Vietnam border, was used to document Chinese experiences and lessons for malaria control and elimination. METHODS: The design was an ecological study. Malaria burden before 1951 and procedures of 64 years (1952-2015) from malaria hyperendemicity to elimination are described...
February 7, 2017: Malaria Journal
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