Karina Dagre Magri, Fang Chia Bin, Fernanda Bellotti Formiga, Thiago da Silveira Manzione, Caroline Merci Caliari de Neves Gomes, Paulo de Azeredo Passos Candelári, Jorge Alberto Ortiz, Wilmar Artur Klug, José Mandia, Peretz Capelhuchnik
OBJECTIVE: to evaluate the effect of neoadjuvant therapy on the stage (TNM) of patients with rectal adenocarcinoma and validate the use of MRI as a method of determining locoregional stage. METHODS: we conducted a retrospective study of 157 patients with lower rectum adenocarcinoma, whom we divided into two groups: Group 1, 81 patients (52%) who had undergone surgical treatment initially, with the purpose to analyze the accuracy of locoregional staging by pelvic magnetic resonance imaging throug the comparison of radiological findings with pathological ones; Group 2, 76 patients (48%), who had been submitted to neoadjuvant therapy (chemotherapy and radiation) prior to definitive surgical treatment, so as to evaluate its effects on the stage by comparing clinical and radiological findings with pathology...
March 2016: Revista do Colégio Brasileiro de Cirurgiões