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Appropriate technology

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https://www.readbyqxmd.com/read/28526046/balloon-versus-stenting-in-severe-ischaemia-of-the-leg-3-basil-3-study-protocol-for-a-randomised-controlled-trial
#1
Benjamin D Hunt, Matthew A Popplewell, Huw Davies, Lewis Meecham, Hugh Jarrett, Gareth Bate, Margaret Grant, Smitaa Patel, Catherine Hewitt, Lazaros Andronis, Jonathan J Deeks, Andrew Bradbury
BACKGROUND: Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease. The superficial femoral and popliteal arteries are the most commonly diseased vessels in such patients and are being increasingly treated using endovascular revascularisation techniques. However, it is currently unknown whether drug-eluting stents and drug-coated balloons confer additional clinical benefits over more established techniques using plain balloons and bare metal stents, or whether they represent a cost-effective use of NHS resources...
May 19, 2017: Trials
https://www.readbyqxmd.com/read/28525321/characteristics-of-the-life-habits-of-obese-students-at-one-of-japan-s-national-colleges-of-technology
#2
Yoshinori Nagasawa, Shin-Ichi Demura, Shigeru Shimada
Aim This study clarified the characteristics of life habits of obese Japanese male students at the National Colleges of Technology, Japan. Materials and methods Healthy students aged 15-19 years answered a questionnaire containing 21 items on the following five categories of life habits: general exercise, meals, sleeping, leisure activity and illness or injury history. The subjects were divided into three groups based on the criteria of body mass index (BMI) and body fat percentage (%BF): non-obese (%BF < 20%, n = 420), overweight obese (%BF ≥ 20% and BMI ≥ 25, n = 99), and hidden obese (%BF ≥ 20% and BMI < 25, n = 60)...
May 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28525312/evaluation-of-the-introduction-of-an-e-health-skills-component-for-dietetics-students
#3
Megan E Rollo, Clare E Collins, Lesley MacDonald-Wicks
BACKGROUND: Appropriate and effective use of technology within practice is a key competency outlined in Australian dietetics training standards. An e-health skills component (lecture and workshop) was introduced to undergraduate students enrolled in an Australian nutrition and dietetics program. METHODS: The lecture orientated students to key e-health terms and concepts relating to telehealth and m-health technologies, while the workshop provided an opportunity to apply knowledge...
May 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28524737/utilizing-next-generation-sequencing-in-the-management-of-multiple-myeloma
#4
Marta Lionetti, Antonino Neri
Multiple myeloma (MM) is a bone marrow plasma cell malignancy characterized by wide clinical presentation and heterogeneous genetic background. Despite the recent advances in patient outcome, new markers are needed for improving risk prediction and choice of a more appropriate therapy. In this perspective, the genetic makeup of MM cells is being better characterized by means of next-generation sequencing (NGS) technologies. Areas covered: The authors discuss how the application of NGS has improved our knowledge of MM biology by discovering its mutational landscape, identifying the operating mutational processes, and revealing the clonal composition of tumors and the dynamics of its evolution; and how this can have important clinical implications in terms of prognostication, therapeutic choices, and response assessment...
May 19, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28523994/potential-biomolecules-and-current-treatment-technologies-for-diabetic-foot-ulcer-an-overview
#5
Zenith Khashim, Shila Samuel, Nallusamy Duraisamy, Kathiravan Krishnan
BACKGROUND: Diabetic foot ulceration remains a major challenge is one of the most expensive and a leading cause of major and minor among patients with a diabetic foot ulcer. Hence the purpose of this review emphases on potential molecular markers involved in diabetic ulcer physiology, the efficacy of different types of dressing materials, therapy and newer therapeutic approach like nanoparticles for the of diabetic foot ulcer. METHODS: We conducted a systematic literature reviews search by using Pubmed and other web search...
May 18, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28521956/comparative-life-cycle-assessment-of-alternative-strategies-for-energy-recovery-from-used-cooking-oil
#6
Lidia Lombardi, Barbara Mendecka, Ennio Carnevale
The separate collection of Used Cooking Oil (UCO) is gaining popularity through several countries in Europe. An appropriate management of UCO waste stream leads to substantial benefits. In this study, we analyse two different possibilities of UCO energy reuse: the direct feed to a reciprocating internal combustion engine (ICE) for cogeneration purpose, and the processing to generate biodiesel. Concerning biodiesel production, we analyse four among conventional and innovative technologies, characterised by different type and amount of used chemicals, heat and electricity consumptions and yields...
May 15, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28521529/potential-of-novel-drug-delivery-systems-in-the-management-of-topical-candidiasis
#7
Mahima Mathur, Kusum Devi Vemula
High prevalence of topical fungal infections is perceived in majority of nations worldwide accounting for numerous serious systemic complications. Of several fungal infections, candidiasis is one of the widespread infections which is manifested due to localization and proliferation of fungi. Present pharmacotherapy offers an effective treatment but possesses serious limitations like inadequate solubility, ineffectiveness in lowering diseased condition and patient incompliance. Several attempts to overcome these shortcomings and building suitable technology platforms for development of appropriate dosage forms which can enhance effectiveness, patient acceptability while maintaining safety, efficacy and affordability of drug delivery, have been made...
May 18, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28518097/light-sheet-based-fluorescence-microscopy-of-living-or-fixed-and-stained-tribolium-castaneum-embryos
#8
Frederic Strobl, Selina Klees, Ernst H K Stelzer
The red flour beetle Tribolium castaneum has become an important insect model organism in developmental genetics and evolutionary developmental biology. The observation of Tribolium embryos with light sheet-based fluorescence microscopy has multiple advantages over conventional widefield and confocal fluorescence microscopy. Due to the unique properties of a light sheet-based microscope, three dimensional images of living specimens can be recorded with high signal-to-noise ratios and significantly reduced photo-bleaching as well as photo-toxicity along multiple directions over periods that last several days...
April 28, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28515699/active-involvement-of-end-users-when-developing-web-based-mental-health-interventions
#9
Derek de Beurs, Inge van Bruinessen, Janneke Noordman, Roland Friele, Sandra van Dulmen
BACKGROUND: Although many web-based mental health interventions are being released, the actual uptake by end users is limited. The marginal level of engagement of end users when developing these interventions is recognized as an important cause for uptake problems. In this paper, we offer our perceptive on how to improve user engagement. By doing so, we aim to stimulate a discourse on user involvement within the field of online mental health interventions. METHODS: We shortly describe three different methods (the expert-driven method, intervention mapping, and scrum) that were currently used to develop web-based health interventions...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28513587/experimental-quantum-compressed-sensing-for-a-seven-qubit-system
#10
C A Riofrío, D Gross, S T Flammia, T Monz, D Nigg, R Blatt, J Eisert
Well-controlled quantum devices with their increasing system size face a new roadblock hindering further development of quantum technologies. The effort of quantum tomography-the reconstruction of states and processes of a quantum device-scales unfavourably: state-of-the-art systems can no longer be characterized. Quantum compressed sensing mitigates this problem by reconstructing states from incomplete data. Here we present an experimental implementation of compressed tomography of a seven-qubit system-a topological colour code prepared in a trapped ion architecture...
May 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28513198/cleaning-and-infection-control-of-airway-clearance-devices-used-by-cf-patients
#11
Eynav Manor, Michal Gur, Yuval Geffen, Lea Bentur
Respiratory treatment for cystic fibrosis (CF) patients includes use of respiratory devices. Contamination of airway clearance devices has not been adequately explored. We aimed to determine whether airway clearance devices are contaminated after use and whether cleaning guidelines for nebulizers are as effective for airway clearance devices. Patients brought their airway clearance devices to the clinic. Swabs from the devices were taken before and after cleaning and were cultured for bacterial counts. Total colony-forming units (CFU) was determined, and predominant colonies were identified using Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry technology...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28511024/cardiopulmonary-exercise-testing-and-surgery
#12
Paul O Older, Denny Zh Levett
The surgical patient population is increasingly elderly and comorbid and poses challenges to perioperative physicians. Accurate pre-operative risk stratification is important to direct perioperative care. Reduced aerobic fitness is associated with increased post-operative morbidity and mortality. Cardiopulmonary exercise testing is an integrated and dynamic test that gives an objective measure of aerobic fitness or functional capacity and identifies the cause of exercise intolerance. Cardiopulmonary exercise testing provides an individualized estimate of patient risk that can be used to predict post-operative morbidity and mortality...
May 16, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28510464/a-stakeholder-perspective-on-diabetes-mellitus-and-diabetic-retinopathy-care-in-iran-a-qualitative-study
#13
Marzieh Katibeh, Masumeh Kalantarion, Silvio Paolo Mariotti, Sare Safi, Saeid Shahraz, Per Kallestrup, Saeed Rahmani, Seyed-Farzad Mohammadi, Alireza Mahdavi, Hamid Ahmadieh
OBJECTIVE: To assess the national health system for management of diabetes mellitus (DM) in Iran, with particular focus on diabetic retinopathy (DR). MATERIALS AND METHODS: In this qualitative study, the national stakeholders related to DR and DM management system were invited to participate. Two researchers performed interview using a semi-structured questionnaire recommended by the World Health Organization titled "Tool for Assessment of Diabetic Retinopathy and DM Management Systems"...
May 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28508376/in-vivo-and-qualitative-studies-investigating-the-translational-potential-of-microneedles-for-use-in-the-older-population
#14
Helen L Quinn, Carmel M Hughes, Ryan F Donnelly
Microneedles (MNs) are a novel transdermal drug delivery platform, rapidly progressing from a substantive evidence base, towards commercialisation. As part of this transition, it is important to consider the future use of MNs by older people in order to ensure optimal therapeutic outcomes for this unique and increasing population group. This paper, therefore, considers the use of MNs by those aged over 65 years, investigating insertion parameters in ageing skin, alongside the feasibility and acceptability of the technology...
May 15, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28508077/resilience-offers-escape-from-trapped-thinking-on-poverty-alleviation
#15
REVIEW
Steven J Lade, L Jamila Haider, Gustav Engström, Maja Schlüter
The poverty trap concept strongly influences current research and policy on poverty alleviation. Financial or technological inputs intended to "push" the rural poor out of a poverty trap have had many successes but have also failed unexpectedly with serious ecological and social consequences that can reinforce poverty. Resilience thinking can help to (i) understand how these failures emerge from the complex relationships between humans and the ecosystems on which they depend and (ii) navigate diverse poverty alleviation strategies, such as transformative change, that may instead be required...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28507980/hypertension-in-the-pediatric-kidney-transplant-recipient
#16
REVIEW
Olga Charnaya, Asha Moudgil
Hypertension after kidney transplant is a frequent occurrence in pediatric patients. It is a risk factor for graft loss and contributes to the significant burden of cardiovascular disease (CVD) in this population. The etiology of posttransplant hypertension is multifactorial including donor factors, recipient factors, medications, and lifestyle factors similar to those prevalent in the general population. Ambulatory blood pressure monitoring has emerged as the most reliable method for measuring hypertension in pediatric transplant recipients, and many consider it to be essential in the care of these patients...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28507410/isolation-and-identification-of-fungi-associated-with-spoilt-fruits-vended-in-gwagwalada-market-abuja-nigeria
#17
Samuel Mailafia, God'spower Richard Okoh, Hamza Olatunde K Olabode, Ramatu Osanupin
AIM: Annual reports have shown that 20% of fruits and vegetables produced are lost to spoilage. This study was undertaken to isolate and identify fungi that are associated with spoilt fruits commonly sold in Gwagwalada market, Abuja, and recommend appropriate control measure. MATERIALS AND METHODS: The study was conducted in Gwagwalada metropolis, Gwagwalada Area Council of the Federal Capital Territory, Abuja, Nigeria. A total of 100 spoilt fruits which include pawpaw (Carica papaya), orange (Citrus sinensis), tomato (Lycopersicon esculentum), pineapple (Ananas comosus), and watermelon (Citrullus vulgaris) were purchased and examined for the presence of fungal organisms using standard methods...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28507260/reprogramming-cells-from-gulf-war-veterans-into-neurons-to-study-gulf-war-illness
#18
Liang Qiang, Anand N Rao, Gustavo Mostoslavsky, Marianne F James, Nicole Comfort, Kimberly Sullivan, Peter W Baas
Gulf War illness (GWI), which afflicts at least 25% of veterans who served in the 1990-1991 war in the Persian Gulf, is thought to be caused by deployment exposures to various neurotoxicants, including pesticides, anti-nerve gas pills, and low-level nerve agents including sarin/cyclosarin. GWI is a multisymptom disorder characterized by fatigue, joint pain, cognitive problems, and gastrointestinal complaints. The most prominent symptoms of GWI (memory problems, poor attention/concentration, chronic headaches, mood alterations, and impaired sleep) suggest that the disease primarily affects the CNS...
May 16, 2017: Neurology
https://www.readbyqxmd.com/read/28505424/addressing-the-issue-of-microplastics-in-the-wake-of-the-microbead-free-waters-act-a-new-standard-can-facilitate-improved-policy
#19
Jason P McDevitt, Craig S Criddle, Molly Morse, Robert Clark Hale, Charles B Bott, Chelsea M Rochman
The United States Microbead-Free Waters Act was signed into law in December 2015. It is a bipartisan agreement that will eliminate one preventable source of microplastic pollution in the United States. Still, the bill is criticized for being too limited in scope, and also for discouraging the development of biodegradable alternatives that ultimately are needed to solve the bigger issue of plastics in the environment. Due to a lack of an acknowledged, appropriate standard for environmentally safe microplastics, the bill banned all plastic microbeads in selected cosmetic products...
May 15, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28504785/addressing-noncommunicable-diseases-in-primary-care-the-case-of-type-2-diabetes
#20
K M Narayan, E C Rhodes
The rapid growth of noncommunicable diseases represents a formidable global health challenge. Here we use type 2 diabetes as a case study to illustrate the rise of noncommunicable diseases and call attention to the important role of primary care systems in addressing these diseases in low- and middle-income countries. Comprehensive screening for diabetes should be implemented through primary care systems to increase early detection of prediabetes and undiagnosed diabetes - a first step to diabetes prevention and management...
December 2016: Journal of the Royal College of Physicians of Edinburgh
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