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https://www.readbyqxmd.com/read/27914145/differential-cell-count-and-crp-level-in-blood-as-predictors-for-middle-east-respiratory-syndrome-coronavirus-infection-in-acute-febrile-patients-during-nosocomial-outbreak
#1
Ga Eun Park, Cheol In Kang, Jae Hoon Ko, Sun Young Cho, Young Eun Ha, Yae Jean Kim, Kyong Ran Peck, Jae Hoon Song, Doo Ryeon Chung
A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27914012/biomechanical-investigation-of-titanium-elastic-nail-prebending-for-treating-diaphyseal-long-bone-fractures
#2
Yen-Nien Chen, Pei-Yuan Lee, Chih-Wei Chang, Yi-Hung Ho, Yao-Te Peng, Chih-Han Chang, Chun-Ting Li
This study numerically investigated the deformation of titanium elastic nails prebent at various degrees during implantation into the intramedullary canal of fractured bones and the mechanism by which this prebending influenced the stability of the fractured bone. Three degrees of prebending the implanted portions of the nails were used: equal to, two times, and three times the diameter of the intramedullary canal. Furthermore, a simulated diaphyseal fracture with a 5-mm gap was created in the middle shaft portion of the bone fixed with two elastic nails in a double C-type configuration...
December 2, 2016: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/27914011/activation-of-alpha-7-nicotinic-acetylcholine-receptor-reduces-brain-edema-in-mice-with-ischemic-stroke-and-bone-fracture
#3
Dingquan Zou, Man Luo, Zhenying Han, Lei Zhan, Wan Zhu, Shuai Kang, Chen Bao, Zhao Li, Jeffrey Nelson, Rui Zhang, Hua Su
Stroke is an important risk factor for bone fracture. We showed previously that bone fracture at the acute stage of ischemic stroke worsens, and activation of α-7 nicotinic acetylcholine receptor (α-7 nAchR) improves, stroke recovery by attenuating inflammation. We hypothesized that activation of α-7 nAchR also improves the blood-brain barrier (BBB) integrity. Permanent distal middle cerebral artery occlusion (pMCAO) was performed on C57BL/6J mice followed by tibia fracture 1 day later. Mice were treated with 0...
December 2, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27913866/communicating-branches-between-lingual-and-hypoglossal-nerve-observation-using-sihler-s-staining-technique
#4
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Yoko Tabira, Moriyoshi Nakamura, Christian Fisahn, R Shane Tubbs, Jingo Kusukawa, Koh-Ichi Yamaki
PURPOSE: Many dental procedures are at risk of injuring the lingual nerve. We performed this study to better elucidate the microanatomy that exists between the ipsilateral lingual and hypoglossal nerves so that iatrogenic injury can be avoided. METHODS: Adult human cadaveric tongues (ten sides) underwent Sihler's staining to identify the microanatomy between the lingual and hypoglossal nerves. RESULTS: The lingual nerve entered the middle part of the anterior two-thirds of the tongue from its lateral side and divided into two to four thick branches...
December 2, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27913859/complex-genetics-architecture-contributes-to-salmonella-resistance-in-acb60-mice
#5
Sean Beatty, Leïla Rached-D'Astous, Danielle Malo
Human infection with Salmonella is of global public health concern. In low- and middle-income countries, Salmonella infection is a major source of disease in terms of both mortality and morbidity, while in high-income nations, the pathogen is an ongoing threat to food security. The outcome of infection with Salmonella enterica serovar Typhimurium (Salmonella Typhimurium) in mouse models is dependent upon a coordinated and complex immune response. A panel of recombinant congenic strains (RCS) derived from the reciprocal double backcross of A/J and C57BL/6J mice has been screened for their susceptibility to Salmonella infection, and the RCS AcB60 was identified to be the most resistant strain to Salmonella infection, more resistant than the parental strain A/J...
December 2, 2016: Mammalian Genome: Official Journal of the International Mammalian Genome Society
https://www.readbyqxmd.com/read/27913820/cerebral-blood-flow-transit-time-and-apparent-diffusion-coefficient-in-moyamoya-disease-before-and-after-acetazolamide
#6
Christian Federau, Soren Christensen, Zungho Zun, Sun-Won Park, Wendy Ni, Michael Moseley, Greg Zaharchuk
INTRODUCTION: The goal of this study was to assess the changes in arterial spin labeling (ASL) cerebral blood flow (CBF) and arterial transit time (ATT), and in apparent diffusion coefficient (ADC), before and after an acetazolamide challenge in moyamoya patients, as function of arterial stenosis severity. METHODS: Pre-operative patients diagnosed with moyamoya disease who could undergo MRI at 3.0T were recruited for this study. A multi-delay pseudo-continuous ASL and a diffusion-weighted sequence were acquired before and 15 min after acetazolamide injection...
December 2, 2016: Neuroradiology
https://www.readbyqxmd.com/read/27913802/combined-use-of-a-pconus-and-a-solitaire-stent-report-of-two-cases
#7
Pervinder Bhogal, Marta Aguilar Pérez, Rosa Martinez Moreno, Marcin Miś, Maciej Miś, Hans Henkes
OBJECTIVE: The aim of this study was to report our initial experience of the use of the pCONus neck protection device in conjunction with the Solitaire AB stent to assist in the endovascular management of complex intracranial aneurysms with arteries arising from both the neck and the dome of the aneurysm. METHODS: Two patients with unruptured aneurysms underwent elective endovascular management of their aneurysms, one arising from the middle cerebral artery bifurcation and one from the anterior communicating artery...
December 2, 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/27913760/neighborhood-physical-disorder-and-psychological-distress-does-the-risk-increase-with-age
#8
Manacy Pai, Joongbaeck Kim
Although research documents a link between neighborhood physical disorder and psychological distress, we know little about the extent to which this association varies by age. Utilizing the person-environment fit model and drawing on data from the fourth wave of the Americans' Changing Lives Survey, we examine the extent to which age influences the association between perceptions of neighborhood physical disorder and psychological distress, as measured by depressive symptoms. We employ both continuous and categorical measures of age to test for a potential moderating effect...
December 2, 2016: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/27913712/money-now-money-later-linking-time-discounting-and-criminal-convictions-in-the-cambridge-study-in-delinquent-development
#9
Alex R Piquero, David P Farrington, Wesley G Jennings
Two prominent criminological theories offer time discounting, or the preference for an immediate reward over a later one, as a central part of understanding involvement in criminal activity. Yet, there exist only a few studies investigating this issue, and they are limited in a few respects. The current study extends prior work in this area by using multiple measures of time discounting collected at three different periods of the life course to examine the link to criminal offending into late middle adulthood in the Cambridge Study in Delinquent Development...
December 1, 2016: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/27913627/aberrant-interhemispheric-homotopic-functional-and-structural-connectivity-in-amyotrophic-lateral-sclerosis
#10
Jiuquan Zhang, Bing Ji, Jun Hu, Chaoyang Zhou, Longchuan Li, Zhihao Li, Xuequan Huang, Xiaoping Hu
OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is an idiopathic and fatal neurodegenerative disease of the human motor system. While microstructural alterations in corpus callosum (CC) have been identified as a consistent feature of ALS, studies directly examining interhemispheric neural connectivity are still lacking. To shed more light on the pathophysiology of ALS, the present study aims to examine alterations of interhemispheric structural and functional connectivity in individuals with ALS...
December 2, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27913613/socioeconomic-differences-in-health-check-ups-and-medically-certified-sickness-absence-a-10-year-follow-up-among-middle-aged-municipal-employees-in-finland
#11
Kustaa Piha, Hilla Sumanen, Eero Lahelma, Ossi Rahkonen
BACKGROUND: There is contradictory evidence on the association between health check-ups and future morbidity. Among the general population, those with high socioeconomic position participate more often in health check-ups. The main aims of this study were to analyse if attendance to health check-ups are socioeconomically patterned and affect sickness absence over a 10-year follow-up. METHODS: This register-based follow-up study included municipal employees of the City of Helsinki...
December 2, 2016: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/27913539/prevention-of-central-nervous-system-sequelae-in-sickle-cell-disease-without-evidence-from-randomized-controlled-trials-the-case-for-a-team-based-learning-collaborative
#12
Michael R DeBaun, Allison A King
Since 1998, the National Institutes of Health has funded 5 randomized controlled trials (RCTs) for primary and secondary prevention of strokes in children with sickle cell anemia (SCA). In a systematic fashion, these trials have significantly advanced the care of children with SCA. In the absence of an RCT, clinicians are often compelled to make decisions at the bedside, based on experience, observational studies, and principles of hematology. We will provide an initial example that describes how a team-based, learning collaborative developed a multisite standard care protocol with a low budget (<$10 000 per year) to overcome the intrinsic limitations of advancing the care of neurologic complications in sickle cell disease (SCD)...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27913201/early-mortality-and-associated-factors-among-patients-with-stroke-admitted-to-a-large-teaching-hospital-in-tanzania
#13
Kigocha Okeng'o, Pilly Chillo, William K Gray, Richard W Walker, William Matuja
BACKGROUND: Stroke is a major cause of death worldwide and 85.5% of stroke deaths occur in low- and middle-income countries due to stroke. The aim of this study was to investigate correlates and predictors of 30-day mortality in stroke patients in urban Tanzania. METHODS: A prospective 30-day follow-up study was conducted at the Muhimbili National Hospital, Dar es Salaam, Tanzania. We recruited all patients with stroke seen at the Emergency Medicine Department and medical wards...
November 29, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27913106/innovations-in-radiotherapy-technology
#14
I J Feain, L Court, J R Palta, S Beddar, P Keall
Many low- and middle-income countries, together with remote and low socioeconomic populations within high-income countries, lack the resources and services to deal with cancer. The challenges in upgrading or introducing the necessary services are enormous, from screening and diagnosis to radiotherapy planning/treatment and quality assurance. There are severe shortages not only in equipment, but also in the capacity to train, recruit and retain staff as well as in their ongoing professional development via effective international peer-review and collaboration...
November 29, 2016: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27913068/occult-infratemporal-fossa-neurofibroma-presenting-with-persistent-unilateral-tinnitus-and-middle-ear-effusion-more-than-meets-the-eye
#15
Lucas P Carlstrom, Kathryn M Van Abel, Matthew L Carlson, Eric J Moore, Janalee K Stokken
Herein, we present the case of a previously healthy 54year-old female who developed several weeks of unilateral tinnitus and aural fullness. She subsequently underwent unilateral pressure equalization tube placement at an outside institution after exam demonstrated a middle ear effusion, conductive hearing loss and normal nasopharyngoscopy. Ultimately, an MRI revealed an occult mass in the infratemporal fossa (ITF), which was successfully removed via an endoscopic transnasal ITF approach. Following resection of a histopathologically confirmed benign neurofibroma, she reported complete resolution of her symptoms...
November 23, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27912940/panax-ginseng-and-salvia-miltiorrhiza-supplementation-during-eccentric-resistance-training-in-middle-aged-and-older-adults-a-double-blind-randomized-control-trial
#16
Hsin-Fu Lin, Chun-Chung Chou, Hsiao-Han Chao, Hirofumi Tanaka
BACKGROUND: Muscle damage induced by an acute bout of eccentric exercise results in transient arterial stiffening. In this study, we sought to determine the effects of progressive eccentric resistance exercise training on vascular functions, and whether herb supplementation would enhance training adaptation by ameliorating the arterial stiffening effects. METHODS: By using a double-blinded randomized placebo-controlled design, older adults were randomly assigned to either the Panax ginseng and Salvia miltiorrhiza supplementation group (N=12) or the placebo group (N=11)...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27912854/immune-to-ageism-men-s-perceptions-of-age-based-discrimination-in-everyday-contexts
#17
Hanna Ojala, Ilkka Pietilä, Pirjo Nikander
Despite long-term, conceptually and theoretically refined discussions, the phenomenon of ageism still remains empirically under-developed. To better understand the diversity of ageism, its contextual variations and gender-specific dynamics in people's daily lives, this study focuses on how different interactional contexts shape men's perceptions of ageism. Using data from 67 thematic personal interviews with 23 middle and working class men aged 50-70, this study contributes to the sorely lacking, empirically based and nuanced understanding of how ageism is experienced, and adds to the research on the internalization of ageism which to date has primarily focused on older women's experiences...
December 2016: Journal of Aging Studies
https://www.readbyqxmd.com/read/27912851/age-mimicry-a-perspective-on-the-young-old
#18
Thomas Küpper
This essay proposes drawing on Homi K. Bhabha's concept of colonial mimicry to theorize the young-old's imitation of midlife. Bhabha states: "colonial mimicry is the desire for a reformed, recognizable Other, as a subject of a difference that is almost the same, but not quite". On an abstract level, similarities can be found in what is expected of the young-old: the young-old are to orient themselves towards middle-age norms, yet only to a certain degree and only when respecting the allegedly natural differences between the ages of life...
December 2016: Journal of Aging Studies
https://www.readbyqxmd.com/read/27912790/fetal-malformation-in-maternal-toxoplasma-and-rubella-co-infection-in-cameroon-a-case-report
#19
Andreas Ateke Njoh, Sarah Namondo Njoh, Messang Blandine Abizou
BACKGROUND: There has been a recent increase in the number of newborns with brain malformations due to congenital infections, but the impact of these diseases remains largely under ascertained in middle-income and low-income countries. This case report presents a fetal anencephaly following maternal toxoplasma and rubella co-infection in a resource-limited setting and the challenges faced by the patient and the health care provider in the management of the condition. CASE PRESENTATION: A 25-year-old black Cameroonian woman of Bakossi origin, gravida3 para1010, presented with a positive rubella and toxoplasma immunoglobulin G serologic test at 21 weeks of pregnancy; she could not benefit from a fetal morphologic ultrasound partly because there was none at the site of her antenatal clinic and because there were accessibility constraints getting to the nearest referral hospital approximately 100 km away...
December 3, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27912780/the-influence-of-cost-per-daly-information-in-health-prioritisation-and-desirable-features-for-a-registry-a-survey-of-health-policy-experts-in-vietnam-india-and-bangladesh
#20
Yot Teerawattananon, Sripen Tantivess, Inthira Yamabhai, Nattha Tritasavit, Damian G Walker, Joshua T Cohen, Peter J Neumann
BACKGROUND: Economic evaluation has been implemented to inform policy in many areas, including coverage decisions, technology pricing, and the development of clinical practice guidelines. However, there are barriers to evidence-based policy in low- and middle-income countries (LMICs) that include limited stakeholder awareness, resources and data availability, as well as the lack of capacity to conduct country-specific economic evaluations. This study aims to survey health policy experts' opinions on barriers to use of cost-effectiveness data in these settings and to obtain their advice on how to make a new cost-per-DALY database being developed by Tufts Medical Center more relevant to LMICs...
December 3, 2016: Health Research Policy and Systems
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