Munish Kumar, Tanavi Sharma, Krishna Patel, Shobia Chinnapparaj, Ravi Dixit, Chandrashekhar Gendle, Ashish Aggarwal, Aastha Takkar, Tulika Gupta, Navneet Singla, Arnab Pal, Pravin Salunke, Sivashanmugam Dhandapani, Rajesh Chabra, Aditi Chatterjee, Harsha Gowda, Hemant Bhagat
Cerebral vasospasm (CV) is a significant complication following aneurysmal subarachnoid hemorrhage (aSAH), and lacks a comprehensive molecular understanding. Given the temporal trajectory of intracranial aneurysm (IA) formation, its rupture, and development of CV, altered gene expression might be a molecular substrate that runs through these clinical events, influencing both disease inception and progression. Utilizing RNA-Seq, we analyzed tissue samples from ruptured IAs with and without vasospasm to identify the dysregulated genes...
May 7, 2024: Omics: a Journal of Integrative Biology