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Laurent Gautron
No abstract text is available yet for this article.
October 2015: Endocrinology
J E Blalock, E M Smith
In a recent commentary (Nature 309, 400; 1984) John Maddox suggested that the study of psychological effects on immunologic functions - 'psychoimmunology' - was somewhat premature. Specifically, he argued that while the concept of a link between the central nervous system and the immune system was easily accepted, there was a paucity of data of a mechanistic nature to explain the evidence that the 'mind' can control immune responses. He doubted, therefore, whether enough is known to sustain the hope that psychoimmunology was explainable...
April 1985: Immunology Today
S I Rapoport, I M Kvetnoĭ, A N Il'nitskiĭ, K I Proshchaev, N I Zhernakova, A Pozharskis, D S Medvedev, G I Gurko, K V Perelygin
Neuroimmunoendocrinology is a new science studying the interplay between major regulatory systems (nervous, endocrine, and immune) mediated through regulatory (signal) molecules. Its applied aspects concern elucidation of the influence of various exogenous factors on the organism manifested as alteration of signal molecule homeostasis. Effects of ethanol on organ systems are considered from the standpoint of neuroimmunoendocrinology.
2012: Klinicheskaia Meditsina
E Hagforsen, G Michaëlsson, M Stridsberg
BACKGROUND: The acrosyringium is the target for inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP). The sweat-gland apparatus seems to be an immunocompetent structure that probably contributes to skin defence. Furthermore, the sweat gland and duct may be a hitherto unrecognized neuroendocrine organ. AIM: To obtain further information about the neuroendocrine properties of the sweat-gland apparatus by examining expression of the somatostatin receptors (SSTRs) 1-5 in healthy palmar skin and in PPP skin...
July 2011: Clinical and Experimental Dermatology
S I Rapoport, N I Zhernakova, A N Il'nitskiĭ, K I Proshchaev, P N Zeliugin
A rationale is proposed for the principles and strategy of non-medicamentous therapy of duodenal ulcer (DU) developing in the advanced age and assessment of its socio-medical efficiency. Staged treatment was given to 234 patients in whom DU was diagnosed between 61 and 65 (mean 63.2) years of age. Basic therapy and long-term dynamic follow-up were carried out in outpatient settings (basic stage). The aim of the inpatient treatment was to maintain the previously achieved level of physical working capacity and quality of life (maintenance stage)...
2009: Klinicheskaia Meditsina
Dirk Roosterman, Tobias Goerge, Stefan W Schneider, Nigel W Bunnett, Martin Steinhoff
This review focuses on the role of the peripheral nervous system in cutaneous biology and disease. During the last few years, a modern concept of an interactive network between cutaneous nerves, the neuroendocrine axis, and the immune system has been established. We learned that neurocutaneous interactions influence a variety of physiological and pathophysiological functions, including cell growth, immunity, inflammation, pruritus, and wound healing. This interaction is mediated by primary afferent as well as autonomic nerves, which release neuromediators and activate specific receptors on many target cells in the skin...
October 2006: Physiological Reviews
I G Akmaev
The paper gives analytical consideration of what, as to how evolved current notions of the new branch of neurobiology, the neuroimmunoendocrinology, dealing with integration of the main physiological regulatory systems--netvous, endocrine and immune, with special reference paid to the developmental likeness of their controlling mechanisms, letting to assume their cooperative action. Taking the latter into consideration the opportunity is discussed, suggesting that breakage of those would result in various kinds of disregulatory pathology including autoimmune one...
October 2003: Uspekhi Fiziologicheskikh Nauk
Ronald L Wilder
Adaptation to stressful stimuli, maintenance of homeostasis, and ultimately, survival require bidirectional feedback communication among components of the stress response and immune and endocrine systems. Substantial progress has been made in delineating molecular, cellular, and systemic physiologic mechanisms underlying this communication, particularly mechanisms that target the immune system. For example, our understanding of the immunomodulatory activities of numerous neuroendocrine mediators, such as cortisol, estrogen, testosterone, DHEA, catecholamines, corticotropin-releasing hormone, and adenosine, has advanced substantially...
June 2002: Annals of the New York Academy of Sciences
I G Akmaev, V G Sergeev
Recent information concerning the white fat tissue allows considering it as endocrine system involved in the neuro-immune-endocrine interactions in regulating various aspects of homeostasis. The contribution presented sums up the latest evidence of adipocyte secreting hormones (leptine and resistine), cytokine (TNF alpha), as well as shedlight on mechanisms, involved in control of energy metabolism, immune reactions and food intake monitoring.
April 2002: Uspekhi Fiziologicheskikh Nauk
I G Akmaev
The author reviews the trends in development of views of interaction of the basic regulating systems (nervous, endocrine and immune) supporting control and adaptive functions of the brain. Two historical periods are singled out: the period of neuroendocrinology and neuroimmunoendocrinology. Mechanisms of interaction of brain regulating systems and various autoimmune diseases resulting from defects in the above mechanisms are considered. Development of cooperative interactions of the above regulating systems at early evolutionary stages is suggested...
October 2001: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
I G Akmaev, V V Grinevich
No abstract text is available yet for this article.
January 2001: Bulletin of Experimental Biology and Medicine
V F Moskalenko, N V Vasil'ev, V I Mal'tsev, V M Shubik, E N Gorban', O A Bobyleva, G N Drannik, N V Cherdyntseva, T I Koliada, Iu L Volianskiĭ
Effects, both specific and non-specific, were analysed of ionizing radiation in a comparative evaluation of medical sequels of the Chernobyl disaster and of the Semipalatinsk Range nuclear test. A hypothesis is advanced assuming that development of all major bodily morbid conditions is directly related to the dysfunction of certain complex of organs, the thyroid gland in the first place, the thymus gland known to be a central organ of systemic immunogenesis. A breach in the thymus link triggers harmful cascade reactions of neuroimmunoendocrinological regulation, appeared to be responsible for the pathogenesis of practically all pathologies disclosed...
June 1999: Likars'ka Sprava
V Goffin, B Bouchard, C J Ormandy, E Weimann, F Ferrag, P Touraine, C Bole-Feysot, R A Maaskant, P Clement-Lacroix, M Edery, N Binart, P A Kelly
Prolactin (PRL), secreted by the pituitary, decidua, and lymphoid cells, has been shown to have a regulatory role in reproduction, immune function, and cell growth in mammals. The effects of PRL are mediated by a membrane-bound receptor that is a member of the superfamily of cytokine receptors. Formation of a trimer, consisting of one molecule of ligand and two molecules of receptor, appears to be a necessary prerequisite for biological activity. The function of these receptors is mediated, at least in part, by two families of signaling molecules: Janus tyrosine kinases (JAKs) and signal transducers and activators of transcription (STATs)...
May 1, 1998: Annals of the New York Academy of Sciences
R Olin
Fibromyalgia is an enigmatic long-lasting polysymptomatic disease which has been thought to be caused by peripheral muscle dysfunction or psychological factors. Based on a clinical evaluation of a large series of in-patients and a review of international findings, the article advances the hypothesis of irreversible disturbances of the neuroimmunoendocrinological system as the main cause of this disease. The therapeutic consequences of this hypothesis are discussed.
February 22, 1995: Läkartidningen
(no author information available yet)
No abstract text is available yet for this article.
1988: Progress in Allergy
F Homo-Delarche, F Fitzpatrick, N Christeff, E A Nunez, J F Bach, M Dardenne
Interest in the field of neuroimmunoendocrinology is in full expansion. With regard to this, steroid influence on the immune system, in particular sex steroids and glucocorticoids, has been known for a long time. Sex steroids are part of the mechanism underlying the immune sexual dimorphism, as particularly emphasized in autoimmune diseases. Immunosuppressive and anti-inflammatory effects of glucocorticoids are now considered a physiological negative feedback loop to cytokines produced during an immune and/or inflammatory response...
1991: Journal of Steroid Biochemistry and Molecular Biology
N Azad, L Agrawal, M A Emanuele, M R Kelley, N Mohagheghpour, A M Lawrence, N V Emanuele
No abstract text is available yet for this article.
December 1991: American Journal of Reproductive Immunology: AJRI
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