keyword
MENU ▼
Read by QxMD icon Read
search

transcranial ultrasound

keyword
https://www.readbyqxmd.com/read/29354219/impact-of-hypertension-severity-on-arterial-stiffness-cerebral-vasoreactivity-and-cognitive-performance
#1
Henrique Cotchi Simbo Muela, Valeria A Costa-Hong, Monica Sanches Yassuda, Michel Ferreira Machado, Ricardo de Carvalho Nogueira, Natalia C Moraes, Claudia Maia Memória, Thiago A Macedo, Edson Bor-Seng-Shu, Ayrton Roberto Massaro, Ricardo Nitrini, Luiz A Bortolotto
Aging, hypertension (HTN), and other cardiovascular risk factors contribute to structural and functional changes of the arterial wall. Objective: To evaluate whether arterial stiffness (AS) is related to cerebral blood flow changes and its association with cognitive function in patients with hypertension. Methods: 211 patients (69 normotensive and 142 hypertensive) were included. Patients with hypertension were divided into 2 stages: HTN stage-1 and HTN stage-2...
October 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29343241/clinical-features-and-dysfunctions-of-iron-metabolism-in-parkinson-disease-patients-with-hyper-echogenicity-in-substantia-nigra-a-cross-sectional-study
#2
Shu-Yang Yu, Chen-Jie Cao, Li-Jun Zuo, Ze-Jie Chen, Teng-Hong Lian, Fang Wang, Yang Hu, Ying-Shan Piao, Li-Xia Li, Peng Guo, Li Liu, Qiu-Jin Yu, Rui-Dan Wang, Piu Chan, Sheng-di Chen, Xiao-Min Wang, Wei Zhang
BACKGROUND: Transcranial ultrasound is a useful tool for providing the evidences for the early diagnosis and differential diagnosis of Parkinson disease (PD). However, the relationship between hyper echogenicity in substantia nigra (SN) and clinical symptoms of PD patients remains unknown, and the role of dysfunction of iron metabolism on the pathogenesis of SN hyper echogenicity is unclear. METHODS: PD patients was detected by transcranial sonography and divided into with no hyper echogenicity (PDSN-) group and with hyper echogenicity (PDSN+) group...
January 17, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29334161/the-role-of-neurosonology-in-the-diagnosis-and-management-of-patients-with-carotid-artery-disease-a-review
#3
REVIEW
Odysseas Kargiotis, Apostolos Safouris, Georgios Magoufis, Maria Georgala, Andromachi Roussopoulou, Eleftherios Stamboulis, Konstantinos G Moulakakis, Andreas Lazaris, George Geroulakos, Spyros Vasdekis, Georgios Tsivgoulis
Carotid artery disease (CAD) is a common cause of ischemic stroke with high rates of recurrence. Carotid endarterectomy (CEA) or carotid artery stenting (CAS) are highly recommended for the secondary prevention of symptomatic CAD during the first 14 days following the index event of transient ischemic attack or minor stroke. CEA or CAS may also be offered in selected cases with severe asymptomatic stenosis. Herein, we review the utility of neurosonology in the diagnosis and pre-/peri-interventional assessment of CAD patients who undergo carotid revascularization procedures...
January 15, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29333343/resounding-failure-to-replicate-links-between-developmental-language-disorder-and-cerebral-lateralisation
#4
Alexander C Wilson, Dorothy V M Bishop
Background: It has been suggested that failure to establish cerebral lateralisation may be related to developmental language disorder (DLD). There has been weak support for any link with handedness, but more consistent reports of associations with functional brain lateralisation for language. The consistency of lateralisation across different functions may also be important. We aimed to replicate previous findings of an association between DLD and reduced laterality on a quantitative measure of hand preference (reaching across the midline) and on language laterality assessed using functional transcranial Doppler ultrasound (fTCD)...
2018: PeerJ
https://www.readbyqxmd.com/read/29332078/magnetic-resonance-guided-high-intensity-focused-ultrasound-for-treating-movement-disorders
#5
Young Goo Kim, Eun Jung Kweon, Won Seok Chang, Hyun Ho Jung, Jin Woo Chang
Transcranial magnetic resonance-guided focused ultrasound (MRgFUS) surgery has recently gained favor as a novel, noninvasive alternative to conventional neurosurgery. In contrast to traditional ablative interventions, transcranial MRgFUS surgery is entirely imaging-guided and uses continuous temperature measurements at the target and surrounding tissue taken in real-time. Unlike Gamma Knife radiosurgery, MRgFUS surgery can make a lesion immediately and does not use ionizing radiation. Moreover, since no metallic device is implanted, MR imaging-based diagnosis is not restricted throughout life...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29315509/carotid-plaque-volume-in-patients-undergoing-carotid-endarterectomy
#6
S Ball, S Rogers, K Kanesalingam, R Taylor, E Katsogridakis, C McCollum
BACKGROUND: The main indication for carotid endarterectomy (CEA) is severity of carotid artery stenosis, even though most strokes in carotid disease are embolic. The relationship between carotid plaque volume (CPV) and symptoms of cerebral ischaemia, and the measurement of CPV by minimally invasive tomographic ultrasound imaging, were investigated. METHODS: The volume of the endarterectomy specimen was measured using a validated saline suspension technique in patients undergoing CEA...
January 8, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29280236/advanced-pediatric-neurosonography-techniques-contrast-enhanced-ultrasonography-elastography-and-beyond
#7
REVIEW
Misun Hwang, Becky J Riggs, Joseph Katz, Donna Seyfert, Frances Northington, Robinson Shenandoah, Irina Burd, Justin McArthur, Kassa Darge, Matthew A Thimm, Thierry A G M Huisman
Recent technical advances in neurosonography continue broadening the diagnostic utility, sensitivity, and specificity of ultrasound for detecting intracranial abnormalities bed side. The clinical and functional applications of neurosonography have significantly expanded since the 1980s when transcranial Doppler sonography first allowed anatomic and hemodynamic delineation of the intracranial vessels through the thin temporal skull. In the past few years, contrast-enhanced ultrasonography, elastography, 3D/4D reconstruction tools, and high-resolution microvessel imaging techniques have further enhanced the diagnostic significance of neurosonography...
December 27, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29274774/nanotherapy-for-alzheimer-s-disease-and-vascular-dementia-targeting-senile-endothelium
#8
REVIEW
Joseph S D'Arrigo
Due to the complexity of Alzheimer's disease, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness. Ultrasound-sensitive coated microbubbles (in a targeted lipid nanoemulsion) are available. Versatile small molecule drug(s) targeting multiple pathways of Alzheimer's disease pathogenesis are known. By incorporating such drug(s) into the targeted "lipid-coated microbubble" [LCM]/"nanoparticle-derived" [ND] (or LCM/ND) nanoemulsion type, one obtains a multitasking combination therapeutic for translational medicine...
December 8, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/29231781/dynamic-autoregulation-of-cerebral-blood-flow-measured-non-invasively-with-fast-diffuse-correlation-spectroscopy
#9
Ashwin B Parthasarathy, Kimberly P Gannon, Wesley B Baker, Christopher G Favilla, Ramani Balu, Scott E Kasner, Arjun G Yodh, John A Detre, Michael T Mullen
Cerebral autoregulation (CA) maintains cerebral blood flow (CBF) in the presence of systemic blood pressure changes. Brain injury can cause loss of CA and resulting dysregulation of CBF, and the degree of CA impairment is a functional indicator of cerebral tissue health. Here, we demonstrate a new approach to noninvasively estimate cerebral autoregulation in healthy adult volunteers. The approach employs pulsatile CBF measurements obtained using high-speed diffuse correlation spectroscopy (DCS). Rapid thigh-cuff deflation initiates a chain of responses that permits estimation of rates of dynamic autoregulation in the cerebral microvasculature...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29228074/a-review-of-the-current-therapies-challenges-and-future-directions-of-transcranial-focused-ultrasound-technology-advances-in-diagnosis-and-treatment
#10
Vibhor Krishna, Francesco Sammartino, Ali Rezai
Importance: Magnetic resonance imaging-guided focused ultrasound ablation has been approved for the treatment of refractory essential tremor and is being studied for other neurological indications, including dyskinesias and tremor in Parkinson disease, dystonia, neuropathic pain, obsessive-compulsive disorder, epilepsy, and brain tumors. Objective: To review the scientific foundations of FUS technology, existing neurological applications, and future advances. Evidence Review: PubMed was searched for the past 10 years using the terms "transcranial ultrasound," "focused ultrasound," and "neurological applications...
December 11, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29219124/3d-printed-adaptive-acoustic-lens-as-a-disruptive-technology-for-transcranial-ultrasound-therapy-using-single-element-transducers
#11
Guillaume Maimbourg, Alexandre Houdouin, Thomas Deffieux, Mickael Tanter, Jean-Francois Aubry
The development of multi-element arrays for better control of the shape of ultrasonic beams has opened the way for focusing through highly aberrating media, such as the human skull. As a result, the use of brain therapy with transcranial-focused ultrasound has rapidly grown. Although effective, such technology is expensive. We propose a disruptive, low-cost approach that consists of focusing a 1-MHz ultrasound beam through a human skull with a single-element transducer coupled with a tailored silicone acoustic lens cast in a 3D-printed mold and designed using computed tomography-based numerical acoustic simulation...
December 8, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29207924/speckle-tracking-in-transcranial-ultrasound-allows-noninvasive-analysis-of-pulsation-patterns-of-the-third-ventricle
#12
Benjamin Würzer, Cristina Laza, Jörn Pons-Kühnemann, Manfred Kaps, Bernd Junge, Florian C Roessler
Cerebrospinal fluid (CSF) flow is sensitive to many cerebral disorders. We aimed to develop a noninvasive bedside method to detect physiological and pathological CSF phenomena by measuring pulsation patterns of the third ventricle. By transcranial B-mode ultrasound, electrocardiography (ECG)-gated video loops of the third ventricle were acquired. "Speckle tracking" software was used to quantify the relative change of its width. We conducted measurements of nine cardiac cycles in 11 healthy subjects in sitting and in supine position during Valsalva maneuver to investigate the influence of an increased intracranial pressure on the relative deformation of the third ventricle...
December 1, 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/29189269/comparison-of-transcranial-doppler-and-ultrasound-tagged-near-infrared-spectroscopy-for-measuring-relative-changes-in-cerebral-blood-flow-in-human-subjects
#13
Michael S Lipnick, Elizabeth A Cahill, John R Feiner, Philip E Bickler
BACKGROUND: Currently, no reliable method exists for continuous, noninvasive measurements of absolute cerebral blood flow (CBF). We sought to determine how changes measured by ultrasound-tagged near-infrared spectroscopy (UT-NIRS) compare with changes in CBF as measured by transcranial Doppler (TCD) in healthy volunteers during profound hypocapnia and hypercapnia. METHODS: Ten healthy volunteers were monitored with a combination of TCD, UT-NIRS (c-FLOW, Ornim Medical), as well as heart rate, blood pressure, end-tidal PCO2 (PEtCO2), end-tidal O2, and inspired O2...
November 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29158187/white-matter-structural-integrity-and-trans-cranial-doppler-blood-flow-pulsatility-in-normal-aging
#14
Roman Fleysher, Michael L Lipton, Olga Noskin, Tatjana Rundek, Richard Lipton, Carol A Derby
Cerebrovascular diseases underlie many forms of age-related cognitive impairment and the mechanism linking the two is hypothesized to involve adverse changes in white matter (WM) integrity. Despite being systemic, small vessel disease does not uniformly affect WM. We performed voxel-wise analysis of MRI images to examine the association between fractional anisotropy (FA) - a diffusion tensor measure of WM structural integrity - and pulsatility index (PI) - a transcranial Doppler ultrasound measure of abnormal arterial flow - in adults over the age of 70 years who were free of stroke and dementia...
November 17, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29130477/transcranial-doppler-and-lower-extremity-function-in-older-adults-einstein-aging-study
#15
Ali Ezzati, Tatjana Rundek, Joe Verghese, Carol A Derby
OBJECTIVES: To determine whether transcranial Doppler ultrasound (TCD) measures of mean blood flow velocity (MBFV) in the major cerebral arteries are associated with measures of lower extremity function in community-dwelling older adults. DESIGN: Cross-sectional study. SETTING: Community sample. PARTICIPANTS: Individuals aged 70 and older (mean 79.5, 54% female) without dementia participating in the Einstein Aging Study (N = 200)...
November 11, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29129735/arterial-stiffness-and-cerebral-hemodynamic-pulsatility-during-cognitive-engagement-in-younger-and-older-adults
#16
Kevin S Heffernan, Jacqueline A Augustine, Wesley K Lefferts, Nicole L Spartano, William E Hughes, Randall S Jorgensen, Brooks B Gump
This study examined central artery stiffness and hemodynamic pulsatility during cognitive engagement in younger and older adults. METHODS: Vascular-hemodynamic measures were completed in 19 younger (age 35±1yrs) and 20 older (age 69±2yrs) adults at rest and during a Stroop task. Aortic stiffness (carotid-femoral pulse wave velocity, PWV) and carotid pulse pressure (PP) were assessed using applanation tonometry. Carotid stiffness was assessed as a single-point PWV using Doppler Ultrasound...
November 10, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29119369/clinical-importance-of-temporal-bone-features-for-the-efficacy-of-contrast-enhanced-sonothrombolysis-a-retrospective-analysis-of-the-nor-sass-trial
#17
Vojtech Novotny, Aliona Nacu, Christopher E Kvistad, Annette Fromm, Gesche F Neckelmann, Andrej N Khanevski, Haakon Tobro, Ulrike Waje-Andreassen, Halvor Naess, Lars Thomassen, Nicola Logallo
Contrast-enhanced sonothrombolysis (CEST) seems to be a safe and promising treatment in acute ischemic stroke. It remains unknown if temporal bone features may influence the efficacy of CEST. We investigated the association between different temporal bone features on admission computed tomography (CT) scan and the outcome in acute ischemic stroke patients included in the randomized Norwegian Sonothrombolysis in Acute Stroke Study (NOR-SASS). Patients diagnosed as stroke mimics and those with infratentorial stroke or with incorrect insonation were excluded...
November 8, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/29103291/current-and-future-uses-of-transcranial-focused-ultrasound-in-neurosurgery
#18
David S Hersh, Howard M Eisenberg
Focused ultrasound (FUS) produces a region of high intensity at the focal zone of the beam but with minimal effects at adjacent areas, allowing the sonication of deep targets throughout the body. Despite early obstacles to transmitting ultrasound energy through the skull, recent advances in ultrasound technology, software, and real-time monitoring have resulted in a renewed interest in the clinical applications of transcranial FUS. Following extensive pre- clinical studies, ultrasound-induced thermal ablation has been approved by several countries for the treatment of essential tremor, Parkinson's disease, obsessive-compulsive disorder, depression, and neuropathic pain...
November 3, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29076274/transcranial-mri-guided-high-intensity-focused-ultrasound-for-treatment-of-essential-tremor-a-pilot-study-on-the-correlation-between-lesion-size-lesion-location-thermal-dose-and-clinical-outcome
#19
Christian Federau, Maged Goubran, Jarrett Rosenberg, Jaimie Henderson, Casey H Halpern, Veronica Santini, Max Wintermark, Kim Butts Pauly, Pejman Ghanouni
BACKGROUND: Transcranial MR-guided high-intensity focused ultrasound (tcMRgFUS) is a promising noninvasive method to treat medication-refractory essential tremor. PURPOSE/HYPOTHESIS: To define the correlation between lesion size after ablation, thermal dose, and clinical outcome in tcMRgFUS treatment of essential tremor. STUDY TYPE: Retrospective. POPULATION/SUBJECTS/PHANTOM/SPECIMEN/ANIMAL MODEL: Eight patients with medication-refractory essential tremor were treated using a tcMRgFUS system at 3T...
October 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29071698/-movement-disorders-units-and-management-of-motor-fluctuations-in-advanced-parkinson-s-disease
#20
O de Fabregues, A Gironell, D Rossello-Jimenez, E Regueras
INTRODUCTION: Advanced Parkinson's disease (PD) entails complications, such as motor fluctuations. In Spain, medical attention for such cases is often provided in movement disorder units (MDU). AIM: To gain further knowledge of the diagnostic resources and therapeutic approach of MDU. SUBJECTS AND METHODS: A descriptive cross-sectional study was conducted. The researchers designed an on-line questionnaire, addressed to neurologists from MDUs, containing 48 questions about the resources they have available, the number of patients with PD and motor fluctuations that have been attended to, as well as the therapeutic approach, according to the Hoehn and Yahr (HY) scale...
November 1, 2017: Revista de Neurologia
keyword
keyword
34482
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"