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Optical coherence tomography

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https://www.readbyqxmd.com/read/28441670/plaque-erosion-causing-st-segment-elevation-myocardial-infarction-report-of-an-optical-coherence-tomography-documented-case-and-concise-literature-review
#1
Lorenzo Genuardi, Francesco Burzotta, Rocco Vergallo, Filippo Crea
No abstract text is available yet for this article.
June 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28441068/a-controlled-randomized-double-blind-study-to-evaluate-the-safety-and-efficacy-of-chitosan-n-acetylcysteine-for-the-treatment-of-dry-eye-syndrome
#2
Doreen Schmidl, René Werkmeister, Semira Kaya, Angelika Unterhuber, Katarzyna J Witkowska, Renate Baumgartner, Sonja Höller, Maria O'Rourke, Ward Peterson, Annika Wolter, Martin Prinz, Leopold Schmetterer, Gerhard Garhöfer
PURPOSE: This study was designed to evaluate the effect of chitosan-N-acetylcysteine (C-NAC) eye drops on tear film thickness (TFT) in patients with dry eye syndrome (DES). METHODS: This was a controlled, randomized, double-blind clinical investigation with patients assigned to 2 cohorts. In Cohort I, 21 patients were randomized to receive 1 instillation of C-NAC eye drops in 1 eye and placebo (normal saline solution) in the contralateral eye. In Cohort II, 17 patients were randomized to receive C-NAC eye drops once (QD) or twice (BID) daily for 5 days...
April 25, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28441067/anterior-segment-optical-coherence-tomography-angiography-for-identification-of-iris-vasculature-and-staging-of-iris-neovascularization-a-pilot-study
#3
Philipp K Roberts, Debra A Goldstein, Amani A Fawzi
Purpose/Aim of the study: To assess the ability of optical coherence tomographic angiography (OCTA) to visualize the normal iris vasculature as well as neovascularization of the iris (NVI). MATERIALS AND METHODS: Study participants with healthy eyes, patients at risk of NVI development and patients with active or regressed NVI were consecutively included in this cross-sectional observational study. Imaging was performed using a commercially available OCTA system (RTVue- XR Avanti, Optovue Inc...
April 25, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28440591/imaging-collector-channel-entrance-with-a-new-intraocular-micro-probe-swept-source-optical-coherence-tomography
#4
Chen Xin, Xiaoya Chen, Meng Li, Yan Shi, Huaizhou Wang, Ruikang Wang, Ningli Wang
PURPOSE: To describe the use of a newly developed side-viewing catheter probe to provide the cross-sectional images of collector channel entrance (CCE), achieved by swept-source optical coherence tomography (SS-OCT). METHODS: A side-viewing SS-OCT catheter probe was developed that has a core probe diameter of 0.15 mm and an outer diameter of 0.25 mm, for the purpose of imaging CCEs within eye globe. Cadaver eyes harvested from swine and human were used to demonstrate its feasibility...
April 25, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28440260/immortal-ozurdex-a-10-month-follow-up-of-an-intralenticular-implant
#5
B Poornachandra, Vinod B M Kumar, Chaitra Jayadev, Subashchandra H Dorelli, Naresh Kumar Yadav, Rohit Shetty
A 78-year-old male who had received a dexamethasone implant (Ozurdex, Allergan, Inc., Irvine, CA, USA) 15 days back for recalcitrant diabetic macular edema in the left eye came to us for a second opinion. On examination, his corrected distance visual acuity was 20/20 in the right eye and 20/40 in the left eye. Early cataractous changes were present in both eyes. The intraocular pressure was within normal limits. The Ozurdex implant was seen lodged in the posterior cortex of the crystalline lens in the left eye, confirmed on anterior segment optical coherence tomography (OCT) and ultrasound biomicroscopy...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440258/neuroretinitis-as-presenting-and-the-only-presentation-of-lyme-disease-diagnosis-and-management
#6
Brahm Prakash Guliani, Sandeep Kumar, Neha Chawla, Anuj Mehta
We present a case of neuroretinitis as presenting and the only presentation of Lyme disease in a 25-year-old female who visited hilly areas in the Himalayas of North India. She presented with right eye sudden and painless blurring of vision. Her vision at presentation was 20/60. She had fundus examination; fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) imaging showed classical features of neuroretinitis. No other organ was involved. Oral steroids were prescribed and relevant investigations sent for noninfective and infective causes...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440254/combined-branch-retinal-vein-and-branch-retinal-artery-occlusion-clinical-features-systemic-associations-and-outcomes
#7
Sabyasachi Sengupta, Utsab Pan
PURPOSE: Retinal vascular occlusions affecting both the arterial and venous systems are rare events. Combined branch retinal artery (BRAO) and vein (BRVO) occlusion are exceedingly rare and not well characterized. METHODS: Six patients with combined BRAO and BRVO underwent a comprehensive eye examination, fundus fluorescein angiography, optical coherence tomography, and cardiovascular evaluation. RESULTS: Mean age at presentation was 54 ± 7...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440249/innovations-in-pediatric-cataract-surgery
#8
Sudarshan Kumar Khokhar, Ganesh Pillay, Esha Agarwal, Manish Mahabir
Advances in technology have made surgery in children safer and faster. The management of pediatric cataract has made rapid progress in the past decade with the availability of safer anesthesia, newer technique's, more predictable intraocular lens (IOL) power calculation, a better understanding of neurobiology, genetics, amblyopia management, improved IOL designs for preventing visual axis opacification, and adjuvant postoperative care. Modern vitrectomy machines with minimally invasive instruments, radiofrequency, diathermy, and plasma blades help immensely in complicated cases...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28439729/macular-morphology-in-former-preterm-and-full-term-infants-aged-4-to-10%C3%A2-years
#9
Achim Fieß, Johannes Janz, Alexander K Schuster, Ruth Kölb-Keerl, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
OBJECTIVE: To analyse macular retinal and choroidal layer thickness in former preterm and full-term infants and to assess associated perinatal influence factors and functional correlation. METHODS: This prospective controlled, cross-sectional, hospital-based study in a tertiary center of maximum care examined former preterm infants with a gestational age (GA) ≤ 32 weeks and full-term neonates currently aged 4 to 10 years. We investigated data from 397 infants, analysing total foveal retinal thickness and six distinct macular retinal layer and choroidal layer measurements via spectral-domain optical coherence tomography...
April 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28439123/in-vivo-molecular-optical-coherence-tomography-of-lymphatic-vessel-endothelial-hyaluronan-receptors
#10
Peng Si, Debasish Sen, Rebecca Dutta, Siavash Yousefi, Roopa Dalal, Yonatan Winetraub, Orly Liba, Adam de la Zerda
Optical Coherence Tomography (OCT) imaging of living subjects offers increased depth of penetration while maintaining high spatial resolution when compared to other optical microscopy techniques. However, since most protein biomarkers do not exhibit inherent contrast detectable by OCT, exogenous contrast agents must be employed for imaging specific cellular biomarkers of interest. While a number of OCT contrast agents have been previously studied, demonstrations of molecular targeting with such agents in live animals have been historically challenging and notably limited in success...
April 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28438153/damage-to-the-macula-associated-with-led-derived-blue-laser-exposure-a-case-report
#11
Lingling Liang, Zhihua Cui, Chengwei Lu, Qian Hao, Yajuan Zheng
BACKGROUND: Light emitting diodes laser is emerging as an important source of light replacing conventional lights. It is widely used for illumination in the bar where young people love to go. But not everyone knows about the light damage to the eye especially to the macula. In this article, we report the case of a macular damage induced by LED-derived blue laser in a bar, studied with optical coherence tomography (OCT) to evaluate the retinal lesion and multifocal electroretinography (mfERG) to evaluate functional damage...
April 24, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28437528/automated-staging-of-age-related-macular-degeneration-using-optical-coherence-tomography
#12
Freerk G Venhuizen, Bram van Ginneken, Freekje van Asten, Mark J J P van Grinsven, Sascha Fauser, Carel B Hoyng, Thomas Theelen, Clara I Sánchez
Purpose: To evaluate a machine learning algorithm that automatically grades age-related macular degeneration (AMD) severity stages from optical coherence tomography (OCT) scans. Methods: A total of 3265 OCT scans from 1016 patients with either no signs of AMD or with signs of early, intermediate, or advanced AMD were randomly selected from a large European multicenter database. A machine learning system was developed to automatically grade unseen OCT scans into different AMD severity stages without requiring retinal layer segmentation...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28437524/the-evolution-of-the-plateau-an-optical-coherence-tomography-signature-seen-in-geographic-atrophy
#13
Anna C S Tan, Polina Astroz, Kunal K Dansingani, Jason S Slakter, Lawrence A Yannuzzi, Christine A Curcio, K Bailey Freund
Purpose: Histologic details of progression routes to geographic atrophy (GA) in AMD are becoming available through optical coherence tomography (OCT). We studied the origins and evolution of an OCT signature called plateau in eyes with GA and suggested a histologic correlate. Methods: Serial eye-tracked OCT scans and multimodal imaging were acquired from eight eyes of seven patients with GA and plateau signatures over a mean follow-up of 7.7 years (range, 3.7-11...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28437483/quantitative-microvascular-analysis-of-retinal-venous-occlusions-by-spectral-domain-optical-coherence-tomography-angiography
#14
Nicole Koulisis, Alice Y Kim, Zhongdi Chu, Anoush Shahidzadeh, Bruce Burkemper, Lisa C Olmos de Koo, Andrew A Moshfeghi, Hossein Ameri, Carmen A Puliafito, Veronica L Isozaki, Ruikang K Wang, Amir H Kashani
PURPOSE: To quantitatively evaluate the retinal microvasculature in human subjects with retinal venous occlusions (RVO) using optical coherence tomography angiography (OCTA). DESIGN: Retrospective, cross-sectional, observational case series. PARTICIPANTS: Sixty subjects (84 eyes) were included (20 BRVO, 14 CRVO, 24 unaffected fellow eyes, and 26 controls). METHODS: OCTA was performed on a prototype, spectral domain-OCTA system in the 3x3mm central macular region...
2017: PloS One
https://www.readbyqxmd.com/read/28437318/results-of-macular-hole-surgery-evaluation-based-on-the-international-vitreomacular-traction-study-classification
#15
Laura Liu, Ijilmurun Enkh-Amgalan, Nan-Kai Wang, Lan-Hsin Chuang, Yen-Po Chen, Yih-Shiou Hwang, Chee-Jen Chang, Kuan-Jen Chen, Wei-Chi Wu, Tun-Lu Chen, Chi-Chun Lai
PURPOSE: To evaluate the differences in anatomical and visual function changes after macular hole (MH) surgery using the International Vitreomacular Traction Study classification. METHODS: Patients who underwent vitrectomy and blood-assisted internal limiting membrane peeling because of MHs were enrolled in the present study. The patients were divided into three groups according to the sizes of their MHs (small: ≤250 μm, medium: >250 μm and ≤400 μm, and large: >400 μm)...
April 20, 2017: Retina
https://www.readbyqxmd.com/read/28436839/automatic-subretinal-fluid-segmentation-of-retinal-sd-oct-images-with-neurosensory-retinal-detachment-guided-by-enface-fundus-imaging
#16
Menglin Wu, Qiang Chen, Xiaojun He, Ping Li, Wen Fan, Songtao Yuan, Hyunjin Park
OBJECTIVE: Accurate segmentation of neurosensory retinal detachment (NRD)-associated subretinal fluid in spectral domain optical coherence tomography (SD-OCT) is vital for the assessment of central serous chorioretinopathy (CSC). A novel two-stage segmentation algorithm was proposed, guided by Enface fundus imaging. METHODS: In the first stage, Enface fundus image was segmented using thickness map prior to detecting the fluid-associated abnormalities with diffuse boundaries...
April 18, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28435212/testing-the-clinical-value-of-multifocal-electroretinography-and-microperimetry-and-the-effects-of-intravitreal-therapy-with-ranibizumab-on-macular-function-in-the-course-of-wet-age-related-macular-degeneration-a-1-year-prospective-study
#17
Mihaela Reinsberg, Ralf-Dieter Hilgers, Inger Lüdeke, Khaled Nassar, Swaantje Grisanti, Salvatore Grisanti, Julia Lüke, Matthias Lüke
PURPOSE: To investigate the clinical value of multifocal electroretinography (mfERG) and microperimetry and the effects of intravitreal therapy with ranibizumab (Lucentis(®)) on macular function in the course of neovascular age-related macular degeneration (nAMD). MATERIALS AND METHODS: We conducted a prospective single-arm interventional cohort study with 20 nAMD patients older than 50 years. Examinations were scheduled monthly for 1 year during intravitreal therapy with ranibizumab...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28435210/incidence-of-interface-fluid-syndrome-after-laser-in-situ-keratomileusis-in-egyptian-patients
#18
Amr A Gab-Alla
PURPOSE: To determine the incidence of interface fluid syndrome (IFS) secondary to steroid-induced elevation of intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) in myopic Egyptian patients. METHODS: This retrospective case series study was conducted at El-Gowhara Private Eye Center. The medical records of 1,807 patients (3,489 eyes), who underwent LASIK to correct myopia from April 2012 to December 2015 were included. The patients were operated on and reviewed by one surgeon (AAG) for IFS after LASIK associated with elevation of IOP (as compared to preoperative values)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28435209/increase-in-average-foveal-thickness-after-internal-limiting-membrane-peeling
#19
Kazuyuki Kumagai, Mariko Furukawa, Tetsuyuki Suetsugu, Nobuchika Ogino
PURPOSE: To report the findings in three cases in which the average foveal thickness was increased after a thin epiretinal membrane (ERM) was removed by vitrectomy with internal limiting membrane (ILM) peeling. METHODS: The foveal contour was normal preoperatively in all eyes. All cases underwent successful phacovitrectomy with ILM peeling for a thin ERM. The optical coherence tomography (OCT) images were examined before and after the surgery. The changes in the average foveal (1 mm) thickness and the foveal areas within 500 μm from the foveal center were measured...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28434071/repeatability-and-agreement-of-central-corneal-thickness-measurement-with-non-contact-methods-a-comparative-study
#20
Tarannum Mansoori, Nagalla Balakrishna
PURPOSE: To compare the central corneal thickness (CCT) measurements and reliability of RTVue XR-100 anterior segment optical coherence tomography (AS-OCT), AL-scan optical biometer and Schwind Sirius anterior segment analysis system. METHODS: The CCT was measured in one hundred and twenty-seven eyes of 127 healthy subjects with AS-OCT, AL-scan and Sirius system. Mean CCT was compared among the instruments, and the level of agreement was assessed using Bland-Altman plots...
April 22, 2017: International Ophthalmology
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