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Optical coherence tomography

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https://www.readbyqxmd.com/read/28227922/evaluation-of-effects-of-electrical-stimulation-in-the-retina-with-optical-coherence-tomography
#1
A Gonzalez-Calle, J D Weiland, A Gonzalez-Calle, J D Weiland, A Gonzalez-Calle, J D Weiland
Retinal prostheses provide the capability to blind patients to detect motion and locate large objects. To avoid activating axons of passage, which can create streak-like perceptions, long pulse stimulation can be used to bypass axons and achieve focal retinal activation. Safety is a concern because long pulses require more charge than short pulses to elicit a response from neural tissue. Future implants will require smaller electrodes to improve resolution, but increased charge density may result, which is another safety concern...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227854/3d-reconstruction-of-cochlea-using-optical-coherence-tomography
#2
Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Yuki Uranishi, Hiroshi Tamura, Tatsunori Sakamoto, Yosuke Tona, Tomohiro Kuroda, Kazuya Okamoto, Tuukka Karvonen
Recently, in vivo visualization of the cochlea and the smaller structures inside of it has been achieved by optical coherence tomography (OCT). This makes it possible to use OCT imaging for diagnosis of diseases such as Meniere's disease through measuring the degree of endolymphatic hydrops. To this end, we present a novel method for 3D segmentation of these cochlear OCT images that is based on superpixels and diffusion maps. The method takes as input grayscale volumetric OCT images and outputs a binary image with the segmented cochlea...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227373/comparative-study-of-texture-features-in-oct-images-at-different-scales-for-human-breast-tissue-classification
#3
Yu Gan, Xinwen Yao, Ernest Chang, Syed Bin Amir, Hanina Hibshoosh, Sheldon Feldman, Christine P Hendon, Yu Gan, Xinwen Yao, Ernest Chang, Syed Bin Amir, Hanina Hibshoosh, Sheldon Feldman, Christine P Hendon, Syed Bin Amir, Christine P Hendon, Sheldon Feldman, Yu Gan, Hanina Hibshoosh, Ernest Chang, Xinwen Yao
Breast cancer is the second leading cause of death in women in the United States due to cancer. Early detection of breast cancerous regions will aid the diagnosis, staging, and treatment of breast cancer. Optical coherence tomography (OCT), a non-invasive imaging modality with high resolution, has been widely used to visualize various tissue types within the human breast and has demonstrated great potential for assessing tumor margins. Imaging large resected samples with a fast imaging speed can be accomplished by under-sampling in the spatial domain, resulting in a large image scale...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227372/multimodal-embryonic-imaging-using-optical-coherence-tomography-selective-plane-illumination-microscopy-and-optical-projection-tomography
#4
M Singh, C Wu, D Mayerich, M E Dickinson, I V Larina, K V Larin, M Singh, C Wu, D Mayerich, M E Dickinson, I V Larina, K V Larin, I V Larina, M Singh, K V Larin, D Mayerich, M E Dickinson, C Wu
The murine model is commonly utilized for studying developmental diseases. Different optical techniques have been developed to image mouse embryos, but each has its own set of limitations and restrictions. In this study, we compare the performance of the well-established technique of optical coherence tomography (OCT) to the relatively new methods of selective plane illumination microscopy (SPIM) and optical projection tomography (OPT) to assess murine embryonic development. OCT can provide label free high resolution images of the mouse embryo, but suffers from light attenuation that limits visualization of deeper structures...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227371/dynamic-analysis-of-mental-sweating-of-eccrine-sweat-gland-of-human-fingertip-by-time-sequential-piled-up-en-face-optical-coherence-tomography-images
#5
Masato Ohmi, Yuki Wada, Masato Ohmi, Yuki Wada, Masato Ohmi, Yuki Wada
In this paper, we demonstrate dynamic analysis of mental sweating for sound stimulus of a few tens of eccrine sweat glands by the time-sequential piled-up en face optical coherence tomography (OCT) images with the frame spacing of 3.3 sec. In the experiment, the amount of excess sweat can be evaluated simultaneously for a few tens of sweat glands by piling up of all the en face OCT images. Non-uniformity was observed in mental sweating where the amount of sweat in response to sound stimulus is different for each sweat gland...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227366/automated-in-vivo-3d-high-definition-optical-coherence-tomography-skin-analysis-system
#6
Ai Ping Yow, Jun Cheng, Annan Li, Ruchir Srivastava, Jiang Liu, Damon Wing Kee Wong, Hong Liang Tey, Ai Ping Yow, Jun Cheng, Annan Li, Ruchir Srivastava, Jiang Liu, Damon Wing Kee Wong, Hong Liang Tey, Ai Ping Yow, Jiang Liu, Annan Li, Hong Liang Tey, Jun Cheng, Ruchir Srivastava
The in vivo assessment and visualization of skin structures can be performed through the use of high resolution optical coherence tomography imaging, also known as HD-OCT. However, the manual assessment of such images can be exhaustive and time consuming. In this paper, we present an analysis system to automatically identify and quantify the skin characteristics such as the topography of the surface of the skin and thickness of the epidermis in HD-OCT images. Comparison of this system with manual clinical measurements demonstrated its potential for automatic objective skin analysis and diseases diagnosis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227126/cardiac-muscle-energetics-improved-normalisation-of-heat-using-optical-coherence-tomography
#7
Ming L Cheuk, Callum M Johnston, June-Chiew Han, Denis S Loiselle, Poul M F Nielsen, Andrew J Taberner, Ming L Cheuk, Callum M Johnston, June-Chiew Han, Denis S Loiselle, Poul M F Nielsen, Andrew J Taberner, June-Chiew Han, Callum M Johnston, Poul M F Nielsen, Ming L Cheuk, Denis S Loiselle, Andrew J Taberner
Heat liberated from isolated cardiac muscle has been used to inform us of thermo-mechanical processes that occur during a contraction. However, for comparisons between different samples to be useful, the heat output needs to be normalized to volume. We have implemented an optical coherence tomograph (OCT), together with a flow-through calorimeter, to accurately determine both muscle volume and heat in the same measurement chamber. The heat rate for multiple stimulation frequencies were recorded and normalized to the volume captured by the OCT...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227121/automated-basal-cell-carcinoma-detection-in-high-definition-optical-coherence-tomography
#8
Annan Li, Jun Cheng, Ai Ping Yow, Ruchir Srivastava, Damon Wing Kee Wong, Hong Liang Tey, Jiang Liu, Annan Li, Jun Cheng, Ai Ping Yow, Ruchir Srivastava, Damon Wing Kee Wong, Hong Liang Tey, Jiang Liu, Ai Ping Yow, Jiang Liu, Annan Li, Hong Liang Tey, Jun Cheng, Ruchir Srivastava
Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Conventional diagnosis of BCC requires invasive biopsies. Recently, a high-definition optical coherence tomography (HD-OCT) technique has been developed, which provides a non-invasive in vivo imaging method of skin. Good agreements of BCC features between HD-OCT images and histopathological architecture have been found. Therefore it is possible to automatically detect BCC using HD-OCT. This paper presents a novel BCC detection method that consists of four steps: graph based skin surface segmentation, surface flattening, deep feature extraction and the BCC classification...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226752/classification-of-sd-oct-volumes-with-multi-pyramids-lbp-and-hog-descriptors-application-to-dme-detections
#9
Khaled Alsaih, Guillaume Lemaitre, Join Massich Vall, Mojdeh Rastgoo, Desire Sidibe, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Carol Y Cheung, Fabrice Meriaudeau, Khaled Alsaih, Guillaume Lemaitre, Join Massich Vall, Mojdeh Rastgoo, Desire Sidibe, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Carol Y Cheung, Fabrice Meriaudeau, Guillaume Lemaitre, Dan Milea, Carol Y Cheung, Desire Sidibe, Ecosse Lamoureux, Join Massich Vall, Mojdeh Rastgoo, Fabrice Meriaudeau, Tien Y Wong, Khaled Alsaih
This paper deals with the automated detection of Diabetic Macular Edema (DME) on Optical Coherence Tomography (OCT) volumes. Our method considers a generic classification pipeline with preprocessing for noise removal and flattening of each B-Scan. Features such as Histogram of Oriented Gradients (HOG) and Local Binary Patterns (LBP) are extracted and combined to create a set of different feature vectors which are fed to a linear-Support Vector Machines (SVM) Classifier. Experimental results show a promising sensitivity/specificity of 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226739/automated-segmentation-of-intra-retinal-cysts-from-optical-coherence-tomography-scans-using-marker-controlled-watershed-transform
#10
G N Girish, Abhishek R Kothari, Jeny Rajan, G N Girish, Abhishek R Kothari, Jeny Rajan, Jeny Rajan, G N Girish, Abhishek R Kothari
Optical Coherence Tomography (OCT) has emerged as a major diagnostic modality for retinal imaging. Although OCT generates gross volumetric data, manual analysis of the images for locating or quantifying retinal cysts is a time consuming process. Recently semi- and fully-automatic methods for locating and segmenting retinal cysts have been proposed in the literature. Our paper proposes a fully automatic method for intra-retinal cyst segmentation using marker controlled watershed transform on B-scan images obtained on OCT scanning...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226738/automatic-anterior-chamber-angle-structure-segmentation-in-as-oct-image-based-on-label-transfer
#11
Huazhu Fu, Yanwu Xu, Damon Wing Kee Wong, Jiang Liu, Mani Baskaran, Shamira A Perera, Tin Aung, Huazhu Fu, Yanwu Xu, Damon Wing Kee Wong, Jiang Liu, Mani Baskaran, Shamira A Perera, Tin Aung, Mani Baskaran, Tin Aung, Huazhu Fu, Yanwu Xu, Damon Wing Kee Wong, Jiang Liu, Shamira A Perera
The anterior chamber angle (ACA) plays an important role for diagnosis and treatment of angle-closure glaucoma. Anterior Segment Optical Coherence Tomography (AS-OCT) imaging is qualitative and quantitative assessment for the ACA structure. In this paper, we propose a novel fully automatic segmentation method for anterior chamber angle structure in AS-OCT. In our method, the initial labels are obtained by using label transfer from the AS-OCT reference dataset. Then, these labels are refined and utilized as the landmarks to support the structure segmentation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226529/shearlet-transform-a-good-candidate-for-compressed-sensing-in-optical-coherence-tomography
#12
Lesley-Ann Duflot, Alexandre Krupa, Brahim Tamadazte, Nicolas Andreff, Lesley-Ann Duflot, Alexandre Krupa, Brahim Tamadazte, Nicolas Andreff, Alexandre Krupa, Lesley-Ann Duflot, Brahim Tamadazte, Nicolas Andreff
This paper deals with the development of a fast and smart acquisition technique of Optical Coherence Tomography (OCT) data that has the capability to reconstruct missing data of OCT image. The main objective is to reduce the acquisition time (i.e., increase the frame rate) of an OCT-scan system by choosing a trajectory that covers entirely the image but that does not take all the measurements. The reconstruction of the missing data is achieved by applying an updated Fast Iterative Soft-Thresholding Algorithm (FISTA) on a sparse representation of the image...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226218/assessing-cartilage-biomechanical-properties-techniques-for-evaluating-the-functional-performance-of-cartilage-in-health-and-disease
#13
Benjamin A Lakin, Brian D Snyder, Mark W Grinstaff
Osteoarthritis (OA) affects millions of people and results in weakened hyaline cartilage due to overloading. During joint articulation, hyaline cartilage must withstand high loads while maintaining low friction to prevent wear and tissue loss. Thus, cartilage compressive stiffness and the coefficient of friction are important indicators of the tissue's functional performance. These mechanical properties are often measured ex vivo using mechanical testing regimens, but arthroscopic handheld probes (e.g., for indentation testing, ultrasound, and optical coherence tomography) and noninvasive imaging modalities (e...
February 2, 2017: Annual Review of Biomedical Engineering
https://www.readbyqxmd.com/read/28225726/computer-assisted-retinal-vessel-tortuosity-evaluation-in-novel-mutation-fabry-disease-towards-new-prognostic-markers
#14
Irene San Román, María-Elena Rodríguez, Orsola Caporossi, Claudia Zoppetti, Andrea Sodi, Alessandro Mecocci, David López, Beatriz Rodríguez, Juan-Ramón Gimeno
PURPOSE: Fabry disease is a rare lysosomal storage disorder with systemic involvement. The authors report on a large Fabry family with GLA p.M187R mutation and exhaustive ophthalmologic assessment. METHODS: Comprehensive systemic evaluation and genetic diagnosis were performed. Ophthalmologic evaluation included intraocular pressure/visual acuity measurement, refractometry, slit lamp examination, retinography, and optical coherence tomography. Three parameters quantified retinal vessel tortuosity: sum of angle metrics, product of angle distance, and triangular index...
March 2017: Retina
https://www.readbyqxmd.com/read/28225724/outer-retinal-tubulation-in-retinal-dystrophies
#15
Imoro Z Braimah, Sunila Dumpala, Jay Chhablani
BACKGROUND/PURPOSE: To evaluate the occurrence and characteristics of outer retinal tubulation (ORT) in an Indian population with retinal dystrophies. METHODS: In this retrospective study, 309 eyes of 157 patients with retinal dystrophies including retinitis pigmentosa (RP, 183 eyes), Stargardt disease (STGD, 93 eyes) and Best disease (33 eyes) were reviewed. The demographic details, clinical data including visual acuity, treatment history and good quality spectral domain optical coherence tomography (SD-OCT) scans were collected...
March 2017: Retina
https://www.readbyqxmd.com/read/28225723/characterization-of-macular-choroidal-thickness-in-ischemic-and-nonischemic-diabetic-maculopathy
#16
Jay U Sheth, Anantharaman Giridhar, Bindu Rajesh, Mahesh Gopalakrishnan
PURPOSE: To evaluate changes in macular choroidal thickness in eyes with ischemic and nonischemic diabetic maculopathy. METHODS: Cross-sectional study of enhanced depth imaging optical coherence tomography of patients with diabetes. The diabetic eyes were divided into 3 groups: 1) eyes with no diabetic retinopathy (NDR); 2) those with diabetic retinopathy without macular ischemia (DR/MI-); and 3) those with diabetic retinopathy and macular ischemia (DR/MI+). RESULTS: This analysis included 261 eyes of 160 patients...
March 2017: Retina
https://www.readbyqxmd.com/read/28225721/superficial-foveal-avascular-zone-determined-by-optical-coherence-tomography-angiography-before-and-after-macular-hole-surgery
#17
Takayuki Baba, Masato Kakisu, Tomohiro Nizawa, Toshiyuki Oshitari, Shuichi Yamamoto
PURPOSE: To determine the size of the superficial foveal avascular zone (FAZ) by optical coherence tomography angiography before and after surgery for an idiopathic macular hole. METHODS: A retrospective, observational case series, in which 16 eyes of 16 patients with an idiopathic macular hole were studied. Pars plana vitrectomy was performed with internal limiting membrane peeling. The foveal retinal vasculature was examined by optical coherence tomography angiography, and the area of the superficial FAZ was determined before, and at 1 and 3 months after the surgery...
March 2017: Retina
https://www.readbyqxmd.com/read/28225373/outer-retinal-tubulation-a-case-series
#18
Leticia A Rousso, Julie A Rodman, Brad Sutton, Diana L Shechtman
PURPOSE: The advent of spectral domain optical coherence tomography has led to superb imaging capabilities in addition to enhanced visualization of the retinal layers. Such advancements have led to the identification of a variety of new retinal conditions, including outer retinal tubulations (ORTs). ORTs are ovoid hyporeflective spaces located in the outer retina. The pathogenesis is unclear but seems to involve sublethal injury to the photoreceptors leading to a compensatory reorganization of the photoreceptor layer with the neighboring ellipsoid zone resulting in a hyperreflective border surrounding a central lumen...
March 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28224400/multimodality-imaging-of-pediatric-airways-disease-indication-and-technique
#19
REVIEW
Nicola Stagnaro, Francesca Rizzo, Michele Torre, Giuseppe Cittadini, GianMichele Magnano
Congenital and acquired airway anomalies represent a relatively common albeit diagnostic and therapeutic challenge, even for the most skilled operators in dedicated centers. Airway malformations encompass a wide spectrum of pathologies involving the larynx, trachea and bronchi, esophagus, mediastinal vessels. These developmental lesions are often isolated but the association of two or more anomalies is not infrequent. From the traditional chest X-ray to the newest applications of Optical Coherence Tomography, non- or mini-invasive diagnostic techniques represent useful tools to integrate invasive procedures...
February 21, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28221330/comparison-of-anterior-segment-optical-coherence-tomography-bleb-grading-moorfields-bleb-grading-system-and-intraocular-pressure-after-trabeculectomy
#20
Joanne C Wen, Sandra S Stinnett, Sanjay Asrani
PURPOSE: To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS: A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM) 4, 6, and 12, respectively...
February 17, 2017: Journal of Glaucoma
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