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Intravascular ultrasound

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https://www.readbyqxmd.com/read/29162782/recurrent-early-coronary-stent-thrombosis-under-chronic-disseminated-intravascular-coagulation
#1
Yusuke Oba, Satoshi Hoshide, Tadayuki Mitama, Hajime Shinohara, Takahiro Komori, Tomoyuki Kabutoya, Yasushi Imai, Nobuhiko Ogata, Kazuomi Kario
A 62-year-old Japanese man presented with chest pain indicating that acute myocardial infarction had occurred. Eleven years earlier, he underwent a splenectomy due to idiopathic portal hypertension. Coronary angiography revealed diffuse stenosis, with calcification in the left anterior descending coronary artery (LAD). We performed a primary percutaneous coronary intervention (PCI). We deployed two drug-eluting stents with sufficient minimal cross-sectional stent area by intravascular ultrasound and thrombolysis in myocardial infarction (TIMI) 3 flow...
November 22, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29160047/neoatherosclerosis-from-basic-principles-to-intravascular-imaging
#2
Philipp Nicol, Erion Xhepa, Dmitry Bozhko, Michael Joner
Development of new atherosclerotic lesions within the neointima of stented vessels has been recognized as a novel disease manifestation of atherosclerosis (neoatherosclerosis), often manifesting as in-stent restenosis (ISR) or in-stent thrombosis (ST). The pathobiology of this entity is still not fully understood and definite diagnosis is challenging owing to limitations in resolution of contemporary intravascular imaging modalities and lack of consequent histopathology correlation studies. Yet, intravascular imaging has emerged as the gold standard for the diagnosis of in-stent pathologies, the most routinely used modalities being intravascular ultrasound (IVUS) and optical coherence tomography (OCT)...
November 20, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29157464/characterization-of-coronary-plaque-regions-in-intravascular-ultrasound-images-using-a-hybrid-ensemble-classifier
#3
Yoo Na Hwang, Ju Hwan Lee, Ga Young Kim, Eun Seok Shin, Sung Min Kim
BACKGROUND AND OBJECTIVES: The purpose of this study was to propose a hybrid ensemble classifier to characterize coronary plaque regions in intravascular ultrasound (IVUS) images. METHODS: Pixels were allocated to one of four tissues (fibrous tissue (FT), fibro-fatty tissue (FFT), necrotic core (NC), and dense calcium (DC)) through processes of border segmentation, feature extraction, feature selection, and classification. Grayscale IVUS images and their corresponding virtual histology images were acquired from 11 patients with known or suspected coronary artery disease using 20 MHz catheter...
January 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29155383/efficacy-of-optical-coherence-tomography-derived-morphometric-assessment-in-predicting-the-physiological-significance-of-coronary-stenosis-head-to-head-comparison-with-intravascular-ultrasound
#4
Eisuke Usui, Taishi Yonetsu, Yoshihisa Kanaji, Masahiro Hoshino, Masao Yamaguchi, Masahiro Hada, Rikuta Hamaya, Yoshinori Kanno, Tadashi Murai, Tetsumin Lee, Tsunekazu Kakuta
AIMS: This study aimed to investigate the diagnostic efficacy of optical coherence tomography (OCT) in identifying functional significance via fractional flow reserve (FFR) compared with that of intravascular ultrasound (IVUS). METHODS AND RESULTS: We investigated 203 de novo intermediate coronary lesions of 186 patients who underwent frequency-domain OCT, IVUS and FFR measurements. Diagnostic efficacy of the minimal lumen area (MLA) obtained by OCT (OCT-MLA) and IVUS (IVUS-MLA) in predicting an FFR<0...
November 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29153502/clinical-outcomes-following-intravascular%C3%A2-imaging-guided-versus-coronary-angiography-guided-percutaneous-coronary-intervention-with%C3%A2-stent-implantation-a%C3%A2-systematic-review-and-bayesian-network-meta-analysis-of%C3%A2-31%C3%A2-studies-and-17-882-patients
#5
Sergio Buccheri, Gabriele Franchina, Sara Romano, Sebastiano Puglisi, Giuseppe Venuti, Paolo D'Arrigo, Bruno Francaviglia, Matteo Scalia, Antonio Condorelli, Marco Barbanti, Piera Capranzano, Corrado Tamburino, Davide Capodanno
OBJECTIVES: The authors sought to explore the comparative clinical efficacy of different imaging modalities for guiding percutaneous coronary interventions (PCI). BACKGROUND: Coronary angiography (CA) is the standard imaging modality for intraprocedural guidance of PCI. Intracoronary imaging techniques, including intravascular ultrasound (IVUS) and optical coherence tomography (OCT), can overcome some limitations of CA. METHODS: Comprehensive hierarchical Bayesian network meta-analysis of randomized clinical trials and adjusted observational studies comparing clinical outcomes of PCI with stent implantation guided by CA, IVUS, or OCT...
November 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29152929/the-role-of-echocardiography-in-kawasaki-disease
#6
Brian W McCrindle, Barbara Cifra
Kawasaki disease (KD) is an acute, self-limited vasculitis affecting young children. It can result in coronary artery abnormalities in a significant proportion of patients, especially if the diagnosis is missed or treatment gets delayed. Echocardiography is the imaging modality of choice for detection of coronary artery abnormalities and assessment of myocardial function. It is also useful for characterization and risk stratification of patients with KD. Echocardiography should be performed at the time of diagnosis and then again at 1-2 weeks and 4-6 weeks after treatment, for uncomplicated cases who do not have significant coronary artery involvement...
November 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29151488/impact-of-coronary-stent-fracture-on-restenotic-neointimal-tissue-characterization-after-drug-eluting-stent-implantation
#7
Yasuhiro Uchida, Satoshi Ichimiya, Hideki Ishii, Hideo Oishi, Toshijiro Aoki, Yusuke Miki, Toshiki Kawamiya, Hitoshi Ichimiya, Junji Watanabe, Masaaki Kanashiro, Shinji Hayano, Susumu Suzuki, Tetsuya Amano, Tatsuaki Matsubara, Toyoaki Murohara
Although drug-eluting stents (DESs) reduce the rates of in-stent restenosis (ISR) and subsequent target lesion revascularization, stent fracture (SF) after DES implantation has become an important concern because of its potential association with restenosis and stent thrombosis. We aimed to assess the pathogenic impact of SF on in-stent restenotic neointimal tissue components after DES implantation. We analyzed 43 consecutive patients (14 with SF and 29 without SF) with ISR requiring revascularization after DES implantation between January 2008 and March 2014...
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29150363/development-of-a-3-french-dual-frequency-intravascular-ultrasound-catheter
#8
Chelsea E Munding, Emmanuel Chérin, Isaac Jourard, Jill J Weyers, David E Goertz, Brian K Courtney, F Stuart Foster
Coronary plaque morphology, including plaque size and fibrous cap thickness, is thought to contribute to the risk of plaque rupture and future cardiac events. Dual-frequency intravascular ultrasound has been proposed as a possible technique to visualize both large-scale features and superficial detail of coronary plaque; however, it has not been found to be feasible within the constraints of a clinically functional intravascular ultrasound catheter. In this study, we describe the design and fabrication of a dual-frequency catheter using a bidirectional transducer stack with center frequencies of approximately 30 and 80 MHz...
November 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29148219/breaking-free-from-vascular-confinement-status-and-prospects-for-submicron-ultrasound-contrast-agents
#9
REVIEW
Carly Pellow, David E Goertz, Gang Zheng
The development of encapsulated microbubbles (~1-6 μm) has expanded the utility of ultrasound from soft tissue anatomical imaging to not only functional intravascular imaging, but therapeutic interventions, with compelling studies of elicited biological effects. The large diameter of these bubbles has confined their utility to the vasculature, but converging interdisciplinary research pathways are giving rise to new submicron ultrasound contrast agents capable of extending their effects beyond the vascular compartment...
November 17, 2017: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/29147470/retrospective-analysis-of-inferior-vena-cava-collapsibility-with-point-of-care-ultrasound-and-urine-sodium-and-fena-in-patients-with-early-stage-acute-kidney-injury
#10
Faizan Babar, Gurkeerat Singh, Mustafa Noor, Bruce Sabath
Early stage acute kidney injury (AKI) is an independent risk factor for an increase in mortality. Accurate assessment of volume status is a major challenge during the early stages of acute renal injury. Determining volume status based on the history and physical exam lacks accuracy. Urine sodium and free excretion of sodium (FENa) provide objective evidence of intravascular volume status when interpreted carefully and is helpful to delineate prerenal from intrinsic renal failure. In recent years point of care ultrasound has been used to assess volume status...
2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29146671/predictors-and-long-term-clinical-outcome-of-longitudinal-stent-deformation-insights-from-pooled-analysis-of-korean-multicenter-drug-eluting-stent-cohort
#11
Tae-Min Rhee, Kyung Woo Park, Joo Myung Lee, Michael S Lee, Ki-Hyun Jeon, Hyun-Jae Kang, Bon-Kwon Koo, Jay Young Rhew, Kwang Soo Cha, Jang-Ho Bae, Kyoo-Rok Han, Si-Hoon Park, Woo-Jung Park, Seung-Woon Rha, Seok-Kyu Oh, Hyuck Moon Kwon, Ki-Bae Seung, Taehoon Ahn, Sang-Hyun Kim, Hyo-Soo Kim
BACKGROUND: There are limited data on the frequency of and factors associated with quantitative coronary angiography (QCA)-defined longitudinal stent deformation (LSD) in various contemporary drug-eluting stents platforms. This study sought to evaluate the predictors of LSD and its long-term clinical implication. METHODS AND RESULTS: A patient-level pooled analysis was performed with 7350 lesions in 5871 patients treated with platinum-chromium-based everolimus-eluting stent (Promus Element), cobalt-chromium-based everolimus-eluting stent (Promus/Xience V), or cobalt-chromium-based zotarolimus-eluting stent (Endeavor Resolute)...
November 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29138364/retrograde-cto-pci-of-native-coronary-arteries-via-left-internal-mammary-artery-grafts-insights-from-a-multicenter-u-s-registry
#12
Peter Tajti, Aris Karatasakis, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, Ehtisham Mahmud, James W Choi, Anthony H Doing, Catalin Toma, Barry Uretsky, Santiago Garcia, Jeffrey W Moses, Manish Parikh, Ajay Kirtane, Ziad A Ali, Raja Hatem, Judit Karacsonyi, Barbara A Danek, Bavana V Rangan, Subhash Banerjee, Imre Ungi, Emmanouil S Brilakis
BACKGROUND: Retrograde percutaneous coronary intervention (PCI) of native coronary artery chronic total occlusion (CTO) via left internal mammary artery (LIMA) graft has received limited study. METHODS AND RESULTS: We compared the clinical and procedural characteristics and outcomes of retrograde CTO-PCI through LIMA grafts vs other conduits in a contemporary multicenter CTO registry. The LIMA was used as the collateral channel in 20 of 990 retrograde CTO-PCIs (2...
November 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29135482/long-term-darapladib-use-does-not-affect-coronary-plaque-composition-assessed-using-multimodality-intravascular-imaging-modalities-a-randomized-controlled-study
#13
Woong Gil Choi, Megha Prasad, Ryan Lennon, Rajiv Gulati, Abhiram Prasad, Lilach O Lerman, Amir Lerman
BACKGROUND: Lipoprotein-associated phospholipase A2 (Lp-PLA2) may play a role in plaque progression and vulnerability. We aimed to define plaque characteristics on multimodality intravascular imaging in patients with coronary endothelial dysfunction in response to long-term inhibition of Lp-PLA2 by darapladib. PATIENTS AND METHODS: This is a double-blinded, randomized study screening 70 patients, and enrolling 54 patients with suspected ischemia, without obstructive disease on angiography and with coronary endothelial dysfunction by invasive assessment...
November 10, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29133478/clinical-relevance-of-18-f-sodium-fluoride-positron-emission-tomography-in-noninvasive-identification-of-high-risk-plaque-in-patients-with-coronary-artery-disease
#14
Joo Myung Lee, Ji-In Bang, Bon-Kwon Koo, Doyeon Hwang, Jonghanne Park, Jinlong Zhang, Tong Yaliang, Minseok Suh, Jin Chul Paeng, Yasutsugu Shiono, Takashi Kubo, Takashi Akasaka
BACKGROUND: (18)F-sodium fluoride ((18)F-NaF) positron-emission tomography has been introduced as a potential noninvasive imaging tool to identify plaques with high-risk characteristics in patients with coronary artery disease. We sought to evaluate the clinical relevance of (18)F-NaF uptake using optical coherence tomography (OCT), intravascular ultrasound (IVUS), and coronary computed tomography angiography in patients with coronary artery disease. METHODS AND RESULTS: The target population consisted of 51 prospectively enrolled patients (93 stenoses) who underwent (18)F-NaF positron-emission tomography before invasive coronary angiography...
November 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29122129/a-new-algorithm-for-crossing-chronic-total-occlusions-from-the-asia-pacific-chronic-total-occlusion-club
#15
REVIEW
Scott A Harding, Eugene B Wu, Sidney Lo, Soo Teik Lim, Lei Ge, Ji-Yan Chen, Jie Quan, Seung-Whan Lee, Hsien-Li Kao, Etsuo Tsuchikane
Although the hybrid chronic total occlusion (CTO) algorithm had many excellent recommendations, there has been infrequent adoption in the Asia Pacific region. The Asia Pacific CTO club propose an algorithm for case selection based on the Japan-CTO score and a new CTO algorithm, which is applicable globally. This algorithm allows for differing skill sets and equipment availability and contains practical teaching for CTO percutaneous coronary intervention. Similar to the hybrid algorithm there are 3 main questions that determine whether the primary approach is antegrade or retrograde: 1) is there proximal cap ambiguity; 2) is the distal vessel of poor quality; and 3) are there interventional collaterals present...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29121226/optical-frequency-domain-imaging-vs-intravascular-ultrasound-in-percutaneous-coronary-intervention-opinion-trial-one-year-angiographic-and-clinical-results
#16
Takashi Kubo, Toshiro Shinke, Takayuki Okamura, Kiyoshi Hibi, Gaku Nakazawa, Yoshihiro Morino, Junya Shite, Tetsuya Fusazaki, Hiromasa Otake, Ken Kozuma, Tetsuya Ioji, Hideaki Kaneda, Takeshi Serikawa, Toru Kataoka, Hisayuki Okada, Takashi Akasaka
Aims: Optical frequency domain imaging (OFDI) is a recently developed, light-based, high-resolution intravascular imaging technique. Intravascular ultrasound (IVUS) is a widely used, conventional imaging technique for guiding percutaneous coronary intervention (PCI). We aimed to demonstrate the non-inferiority of OFDI-guided PCI compared with IVUS-guided PCI in terms of clinical outcomes. Methods and results: We did a prospective, multicentre, randomized (ratio 1:1), active-controlled, non-inferiority study to compare head-to-head OFDI vs...
November 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29113866/intravascular-ultrasound-enhances-the-safety-of-rotational-atherectomy
#17
REVIEW
Kenichi Sakakura, Kei Yamamoto, Yousuke Taniguchi, Yoshimasa Tsurumaki, Shin-Ichi Momomura, Hideo Fujita
Intravascular ultrasound (IVUS) is mainly used in PCI to treat complex lesions, such as left main bifurcation, chronic total occlusion and calcified lesions. Although IVUS yields useful information such as the presence of napkin-ring calcification, the role of IVUS in rotational atherectomy (RA) is not fully appreciated. Recently, since the deliverability and crossability of IVUS catheters have improved, IVUS should be attempted before RA. Even if the IVUS catheter cannot cross the lesion, IVUS provides information just proximal to the target lesion, which would be useful in the selection of the appropriate guidewire and burr size...
September 23, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29112510/prediction-of-postpercutaneous-coronary-intervention-myocardial-infarction-insights-from-intravascular-imaging-coronary-flow-and-biomarker-evaluation
#18
Stephen P Hoole, Jules Hernández-Sánchez, Adam J Brown, Joel P Giblett, Martin R Bennett, Nick E J West
BACKGROUND: Percutaneous coronary intervention-induced myocardial infarction (PMI) has prognostic significance. Identifying patients at high risk for PMI is desirable as it may alter strategy and facilitate early preventative therapy. We therefore sought to establish whether preprocedural demographic, interventional (plaque characteristics and coronary microcirculatory function), and inflammatory, endothelial damage, and platelet-derived biomarker data could predict the risk of PMI. PATIENTS AND METHODS: We performed target vessel pressure wire to assess fractional flow reserve, index of microcirculatory resistance (IMR) and coronary flow reserve, plaque characterization by virtual histology intravascular ultrasound, and assayed peripheral biomarkers before uncomplicated PCI in 88 patients...
November 6, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29108400/early-experience-and-favorable-clinical-outcomes-of-everolimus-eluting-bioresorbable-scaffolds-for-coronary-artery-disease-in-korea
#19
Osung Kwon, Jung-Min Ahn, Do-Yoon Kang, Se Hun Kang, Pil Hyung Lee, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
Background/Aims: Compared with metallic drug-eluting stents (DES), bioresorbable vascular scaffolds (BVS) may further improve long-term outcomes of percutaneous coronary intervention (PCI) in patients with coronary artery disease. We report our early experience with BVS in Korea. Methods: We evaluated 105 consecutive patients with BVS implanted at Asan Medical Center, Korea between October 21, 2015 and June 3, 2016. Angiographic results, and in-hospital and 6-month clinical outcomes were assessed...
November 7, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29101838/a-molecular-intravascular-ultrasound-contrast-agent-allows-detection-of-activated-platelets-on-the-surface-of-symptomatic-human-plaques
#20
Alexander Maier, Patricia Plaza-Heck, Fabian Meixner, Felix Guenther, Beat A Kaufmann, Mara Kramer, Timo Heidt, Andreas Zirlik, Ingo Hilgendorf, Jochen Reinöhl, Peter Stachon, Peter Bronsert, Ralf Birkemeyer, Irene Neudorfer, Karlheinz Peter, Christoph Bode, Constantin von Zur Mühlen
BACKGROUND AND AIMS: Activated platelets are amongst the most attractive imaging targets in atherosclerosis due to their important role in early processes of atherogenesis and thrombus formation. We developed a molecular intravascular ultrasound (IVUS) approach to detect activated platelets ex vivo on the surface of human plaques, using an IVUS system applied in clinical routine. METHODS: Human carotid endarterectomy specimens were obtained directly from the operating room and exposed to artificial arterial flow conditions for incubation with the contrast agent...
October 24, 2017: Atherosclerosis
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