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Adenoma detection rate

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https://www.readbyqxmd.com/read/29445907/management-of-serrated-polyps-of-the-colon
#1
REVIEW
Claire Fan, Adam Younis, Christine E Bookhout, Seth D Crockett
PURPOSE OF REVIEW: The purpose of this review is to summarize the management of serrated colorectal polyps (SPs), with a particular focus on the most common premalignant SP, sessile serrated adenoma or polyp (SSA/P). These lesions present a challenge for endoscopists with respect to detection and resection, and are also susceptible to pathologic misdiagnosis. RECENT FINDINGS: Patients with SSA/Ps are at an increased risk of future colorectal neoplasia, including advanced polyps and cancer...
February 14, 2018: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/29441370/adenoma-detection-rate-is-it-the-master-key-for-the-colonoscopy-quality-indicator
#2
EDITORIAL
Su Young Kim, Hyun-Soo Kim
No abstract text is available yet for this article.
2018: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29426056/g-eye-advanced-colonoscopy-for-improved-polyp-detection-rates-a-randomized-tandem-pilot-study-with-different-endoscopists
#3
Johannes Wilhelm Rey, Sebastian Dümcke, Jafer Haschemi, Achim Tresch, Dietmar Borger, Ann-Christin Kirchner, Daniel Teubner, Ralf Kiesslich, Arthur Hoffman
BACKGROUND AND AIMS:  The most commonly missed polyps in colonoscopy are those located behind haustral folds. The G-EYE system is a standard colonoscope consisting of re-processable balloon at its distal tip. The G-EYE balloon improves the detection of polyps by straightening the haustral folds. In our back-to-back tandem study, we aimed to determine whether and to what extent the G-EYE system could reduce adenoma miss rates in screening colonoscopy. METHODS:  Patients referred to colonoscopy were randomized into 2 groups...
February 9, 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29417332/left-sided-colectomy-one-of-the-important-risk-factors-of-metachronous-colorectal-adenoma-after-colectomy-for-colon-cancer
#4
Gee Young Yun, Hee Seok Moon, In Sun Kwon, Ju Seok Kim, Sun Hyung Kang, Eaum Seok Lee, Seok Hyun Kim, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong
BACKGROUND: Patients with a history of colonic resection for cancer have an increased risk for the development of metachronous malignant lesions. However, there is a lack of data on the detection rates of premalignant lesions during colonoscopy surveillance in these patients, and the few existing studies have shown conflicting results. AIMS: To identify the risk factor of metachronous premalignant lesions after colon cancer surgery. METHODS: We retrospectively screened consecutive patients who had undergone colonic surgery to treat colon cancer at the Chungnam National University Hospital between September 2009 and April 2014...
February 8, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29416736/prognostic-and-histogenetic-roles-of-gene-alteration-and-the-expression-of-key-potentially-actionable-targets-in-salivary-duct-carcinomas
#5
Tomotaka Shimura, Yuichiro Tada, Hideaki Hirai, Daisuke Kawakita, Satoshi Kano, Kiyoaki Tsukahara, Akira Shimizu, Soichiro Takase, Yorihisa Imanishi, Hiroyuki Ozawa, Kenji Okami, Yuichiro Sato, Yukiko Sato, Chihiro Fushimi, Hideaki Takahashi, Takuro Okada, Hiroki Sato, Kuninori Otsuka, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Takafumi Togashi, Yushi Ueki, Hisayuki Ota, Mizuo Ando, Shinji Kohsaka, Toyoyuki Hanazawa, Hideaki Chazono, Yoshiyuki Kadokura, Hitome Kobayashi, Toshitaka Nagao
The molecular characteristics of therapeutically-relevant targets and their clinicopathological implications in salivary duct carcinomas (SDCs) are poorly understood. We investigated the gene alterations and the immunoexpression of crucial oncogenic molecules in 151 SDCs. The mutation rates that were identified, in order of frequency, were as follows: TP53 , 68%; PIK3CA , 18%; H-RAS , 16%; BRAF , 4%; and AKT1 , 1.5%. PIK3CA/H-RAS/BRAF mutations were more common in de novo SDC than in SDC ex-pleomorphic adenoma...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29415338/a-statewide-program-providing-colorectal-cancer-screening-to-the-uninsured-of-south-carolina
#6
Jan M Eberth, Annie Thibault, Renay Caldwell, Michele J Josey, Beidi Qiang, Edsel Peña, Delecia LaFrance, Franklin G Berger
BACKGROUND: Cancer screening rates are lowest in those without insurance or a regular provider. Since 2008, the Colorectal Cancer Prevention Network (CCPN) has provided open access colonoscopy to uninsured residents of South Carolina through established, statewide partnerships and patient navigation. Herein, we describe the structure, implementation, and clinical outcomes of this program. METHODS: The CCPN provides access to colonoscopy screening at no cost to uninsured, asymptomatic patients aged 50-64 years (African Americans age 45-64 years are eligible) who live at or below 150% of the poverty line and seek medical care in free medical clinics, federally qualified health centers, or hospital-based indigent practices in South Carolina...
February 7, 2018: Cancer
https://www.readbyqxmd.com/read/29415287/residual-adenoma-after-cold-snare-polypectomy-for-small-colorectal-adenomas-a-prospective-clinical-study
#7
Daisuke Maruoka, Makoto Arai, Naoki Akizue, Kentaro Ishikawa, Shingo Kasamatsu, Takashi Taida, Hideaki Ishigami, Kenichiro Okimoto, Keiko Saito, Tomoaki Matsumura, Tomoo Nakagawa, Tatsuro Katsuno, Naoya Kato
BACKGROUND: Endoscopic resection of all colonic adenomas prevents the occurrence of colon cancer and death. The European Society of Gastrointestinal Endoscopy Clinical Guideline recommends resection of all polyps predicted to be adenomas and cold snare polypectomy (CSP) for removal of adenomas ≤ 9 mm on the basis of safety; however, it also states that this recommendation lacks adequate evidence of efficacy. The residual adenoma rate after resection is an important indicator of efficacy, but there have been no reports showing this prospectively...
February 7, 2018: Endoscopy
https://www.readbyqxmd.com/read/29415286/gaze-patterns-hold-key-to-unlocking-successful-search-strategies-and-increasing-polyp-detection-rate-in-colonoscopy
#8
Mariam Lami, Harsimrat Singh, James H Dilley, Hajra Ashraf, Matthew Edmondon, Felipe Orihuela-Espina, Jonathan Hoare, Ara Darzi, Mikael H Sodergren
BACKGROUND:  The adenoma detection rate (ADR) is an important quality indicator in colonoscopy. The aim of this study was to evaluate the changes in visual gaze patterns (VGPs) with increasing polyp detection rate (PDR), a surrogate marker of ADR. METHODS:  18 endoscopists participated in the study. VGPs were measured using eye-tracking technology during the withdrawal phase of colonoscopy. VGPs were characterized using two analyses - screen and anatomy. Eye-tracking parameters were used to characterize performance, which was further substantiated using hidden Markov model (HMM) analysis...
February 7, 2018: Endoscopy
https://www.readbyqxmd.com/read/29410020/impact-of-2-generational-improvements-of-colonoscopes-on-adenoma-miss-rates-results-of-a-prospective-randomized-multicenter-tandem-study
#9
Mathieu Pioche, Angelique Denis, Hans-Dieter Allescher, Gianluca Andrisani, Guido Costamagna, Evelien Dekker, Paul Fockens, Christian Gerges, Stefan Groth, Jennis Kandler, Isabelle Lienhart, Horst Neuhaus, Lucio Petruzziello, Guido Schachschal, Kristien Tytgat, Jürgen Wallner, Vincens Weingart, Sandrine Touzet, Thierry Ponchon, Thomas Rösch
BACKGROUND AND AIMS: Numerous randomized studies have shown that changing certain features of colonoscopes, usually incorporated when switching from one endoscope generation to the next, mostly do not increase adenoma yield. There is, however, indirect evidence that it may be necessary to skip one instrument generation (ie, changing from one generation to the next but one) to achieve this effect. METHODS: We compared the latest-generation colonoscopes from one company (Olympus Exera III, 190-C) with the next to last one (Olympus 160/5-C) in a prospective multicenter study randomized for the order of colonoscopes in a tandem fashion, involving 2 different examiners...
January 30, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29404934/biochemical-and-pathologic-factors-affecting-technetium-99m-methoxyisobutylisonitrile-imaging-results-in-patients-with-primary-hyperparathyroidism
#10
Aysenur Ozderya, Sule Temizkan, Aylin Ege Gul, Sule Ozugur, Kenan Cetin, Kadriye Aydin
OBJECTIVE: Technetium 99 m methoxyisobutylisonitrile (Tc-99m MIBI) scintigraphy represents the most commonly utilized imaging modality for the detection of the diseased gland in patients with primary hyperparathyroidism (PHPT). In this study, we aimed to identify potential biological factors with an impact on MIBI sensitivity. METHODS: A total of 147 patients with surgically confirmed parathyroid adenomas were assessed retrospectively. Data including medical history, biochemical and hormonal measurements, cervical US, Tc-99m MIBI scans as well as pathology reports were retrieved and recorded...
February 5, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29397494/adenoma-detection-rate-falls-at-the-end-of-the-day-in-a-large-multi-site-sample
#11
Felippe O Marcondes, Rebecca A Gourevitch, Robert E Schoen, Seth D Crockett, Michele Morris, Ateev Mehrotra
BACKGROUND: There is concern that mental and physical fatigue among endoscopists over the course of the day will lead to lower adenoma detection rate (ADR). There are mixed findings in the prior literature on whether such an association exists. AIMS: The aim of this study was to measure the association between the number of colonoscopies performed in a day and ADR and withdrawal time. METHODS: We analyzed 86,624 colonoscopy and associated pathology reports between October 2013 and September 2015 from 131 physicians at two medical centers...
February 3, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29391311/shorter-waiting-times-from-education-to-colonoscopy-can-improve-the-quality-of-bowel-preparation-a-randomized-controlled-trial
#12
Jin Lee, Tae Oh Kim, Joo Wan Seo, Joon Hyuk Choi, Nae Yun Heo, Jongha Park, Seung Ha Park, Sung Yeon Yang, Young Soo Moon
BACKGROUND/AIMS: Adequate bowel preparation is essential for an effective and safe colonoscopy. This study aimed to evaluate the quality of bowel preparation according to waiting times from education to colonoscopy. MATERIALS AND METHODS: A prospective, investigator-blinded, randomized study was performed from December 2016 to March 2017. Patients were divided into two groups: within 2 weeks (group A, n=64) or more than 2 weeks (group B, n=66) from education about bowel preparation to colonoscopy...
January 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29383029/can-technology-increase-adenoma-detection-rate
#13
REVIEW
Wee Sing Ngu, Colin Rees
Colorectal cancer is the third most common cancer worldwide and the second most common cause of cancer-related death in Europe and North America. Colonoscopy is the gold standard investigation for the colon but is not perfect, and small or flat adenomas can be missed which increases the risk of patients subsequently developing colorectal cancer. Adenoma detection rate is the most widely used marker of quality, and low rates are associated with increased rates of post-colonoscopy colorectal cancer. Standards of colonoscopy and adenoma detection vary widely between different endoscopists...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29382240/diagnostic-yield-is-not-influenced-by-the-timing-of-screening-endoscopy-morning-versus-afternoon
#14
Ying Xu, Ke Chen, Lantao Xu, Xiaoqin Yuan, Yunlin Wu, Ping Chen
BACKGROUND: Previous studies have shown the colonoscopy quality affected by the endoscopist's fatigue. This study was aimed to evaluate this potential factor in a colorectal cancer-screening cohort of Chinese patients. METHODS: The attendances at department of gastroenterology for colorectal cancer screening between 2013 and 2015 were retrospectively analyzed. The procedure time-of-day and hours elapse were recorded. The primary outcome was defined as adenoma detection rate (ADR)...
January 30, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29381378/incidentally-detected-bilateral-adrenal-nodules-in-patients-without-cancer-is-further-workup-necessary
#15
Michael T Corwin, James S Chalfant, Thomas W Loehfelm, Ghaneh Fananapazir, Ramit Lamba, William W Mayo-Smith
OBJECTIVE: The purpose of this study was to determine the rate of malignancy in incidentally detected bilateral adrenal masses in patients with no known history of cancer. MATERIALS AND METHODS: A retrospective search of CT reports of patients with incidentally detected bilateral adrenal nodules was performed from January 1, 2002, to January 1, 2014. Patients were excluded if they had a known cancer or suspected functioning adrenal tumor; 161 patients were included...
January 30, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29380819/variation-in-pathologist-classification-of-colorectal-adenomas-and-serrated-polyps
#16
Rebecca A Gourevitch, Sherri Rose, Seth D Crockett, Michele Morris, David S Carrell, Julia B Greer, Reetesh K Pai, Robert E Schoen, Ateev Mehrotra
OBJECTIVES: Endoscopist quality measures such as adenoma detection rate (ADR) and serrated polyp detection rates (SPDRs) depend on pathologist classification of histology. Although variation in pathologic interpretation is recognized, we add to the literature by quantifying the impact of pathologic variability on endoscopist performance. METHODS: We used natural language processing to abstract relevant data from colonoscopy and related pathology reports performed over 2 years at four clinical sites...
January 30, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29378376/-french-comment-on-article-impact-of-preprocedure-simethicone-on-adenoma-detection-rate-during-colonoscopy-a-multicenter-endoscopist-blinded-randomized-controlled-trial
#17
https://www.readbyqxmd.com/read/29374902/-analysis-of-community-colorectal-cancer-screening-in-50-74-years-old-people-in-guangzhou-2015-2016
#18
Y Li, H Z Liu, Y R Liang, G Z Lin, K Li, H Dong, H Xu, M Wang
Objective: To analyze the effect of colorectal cancer screening in the general population in Guangzhou, and provide evidence for the for development of colorectal cancer screening policy and strategy. Methods: The data of colorectal cancer screening in Guangzhou during 2015- 2016 were collected. The participation, the positive rate of fecal occult blood test, the detection rate of colonoscopy and screening effect of colonoscopy were evaluated. Results: A total of 220 834 residents aged 50-74 years received the screening, and the positive rate of the screening was 16...
January 10, 2018: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29373569/efficacy-and-acceptability-of-1-liter-of-polyethylene-glycol-with-ascorbic-acid-vs-2-liters-of-polyethylene-glycol-plus-mosapride-and-sennoside-for-colonoscopy-preparation
#19
Masato Kamei, Tomoyoshi Shibuya, Masahito Takahashi, Masae Makino, Keiichi Haga, Osamu Nomura, Takashi Murakami, Hideaki Ritsuno, Hiroya Ueyama, Tomohiro Kodani, Dai Ishikawa, Kenshi Matsumoto, Naoto Sakamoto, Taro Osada, Tatsuo Ogihara, Sumio Watanabe, Akihito Nagahara
BACKGROUND [color=black]Bowel preparation is an important factor for an optimal outcome of colonoscopy. Recently, polyethylene glycol (PEG) solution has been in common use for bowel cleansing for colonoscopy, but some patients are intolerant of PEG because of taste or volume. A low-volume PEG administered with ascorbic acid solution (PEG-Asc) was designed to improve tolerability, but the administration of this method is more complex than that with PEG alone. This study aimed to compare bowel cleansing efficacy, safety, and tolerability of 1 L PEG-Asc with a 2 L PEG preparation with use of sennosides and mosapride...
January 26, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29363535/improved-adenoma-detection-with-endocuff-vision-the-adenoma-randomised-controlled-trial
#20
Wee Sing Ngu, Roisin Bevan, Zacharias P Tsiamoulos, Paul Bassett, Zoë Hoare, Matthew D Rutter, Gayle Clifford, Nicola Totton, Thomas J Lee, Arvind Ramadas, John G Silcock, John Painter, Laura J Neilson, Brian P Saunders, Colin J Rees
OBJECTIVE: Low adenoma detection rates (ADR) are linked to increased postcolonoscopy colorectal cancer rates and reduced cancer survival. Devices to enhance mucosal visualisation such as Endocuff Vision (EV) may improve ADR. This multicentre randomised controlled trial compared ADR between EV-assisted colonoscopy (EAC) and standard colonoscopy (SC). DESIGN: Patients referred because of symptoms, surveillance or following a positive faecal occult blood test (FOBt) as part of the Bowel Cancer Screening Programme were recruited from seven hospitals...
January 23, 2018: Gut
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