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https://www.readbyqxmd.com/read/28414559/evaluating-the-cost-and-utility-of-mandating-schools-to-stock-epinephrine-auto-injectors
#1
Chelsea Steffens, Benjamin Clement, William Fales, Ahel El Haj Chehade, Kevin Putman, Robert Swor
BACKGROUND: The Michigan Legislature mandated that all public schools stock epinephrine auto-injectors (EAIs). A minimal amount is known regarding the incremental value of EAIs in schools. Our primary objective was to describe the frequency of administration of epinephrine for EMS patients with acute allergic reactions in public schools. Our secondary objective was to estimate the cost of mandating public schools to stock EAIs. METHODS: We performed a retrospective cohort study of EMS cases with an impression of allergic reaction and who received epinephrine recorded in the 2014 Michigan EMS Information System (MI-EMSIS)...
April 17, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28411932/arthropod-envenomation-in-north-america
#2
REVIEW
Timothy B Erickson, Navneet Cheema
Arthropods (phylum Arthopoda) account for a higher percentage of morbidity and mortality to humans than do mammalian bites, snake bites, or marine envenomation. They are ubiquitous in domestic dwellings, caves, and campsites and in wilderness settings such as deserts, forests, and lakes. Although arthropods are most intrusive during warmer months, many are active throughout the winter, particularly indoors. Arthropods are also nocturnal and often bite unsuspecting victims while they are sleeping. Encounters with humans are generally defensive, accidental, or reactive...
May 2017: Emergency Medicine Clinics of North America
https://www.readbyqxmd.com/read/28390586/an-analysis-of-anaphylaxis-cases-at-a-single-pediatric-emergency-department-during-a-1-year-period
#3
Christopher D Wright, Mindy Longjohn, Phillip L Lieberman, Jay Adam Lieberman
BACKGROUND: Case series of anaphylaxis can vary regarding causes, treatments, and follow-up of patients. Unfortunately, case series that are specific to the pediatric population are few. OBJECTIVE: To describe confirmed cases of pediatric anaphylaxis in patients presenting to a pediatric hospital emergency department (ED). METHODS: We identified all ED visits with the International Classification of Diseases, Ninth Revision (ICD-9) codes 995...
April 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28376325/phylogenomic-insights-into-the-evolution-of-stinging-wasps-and-the-origins-of-ants-and-bees
#4
Michael G Branstetter, Bryan N Danforth, James P Pitts, Brant C Faircloth, Philip S Ward, Matthew L Buffington, Michael W Gates, Robert R Kula, Seán G Brady
The stinging wasps (Hymenoptera: Aculeata) are an extremely diverse lineage of hymenopteran insects, encompassing over 70,000 described species and a diversity of life history traits, including ectoparasitism, cleptoparasitism, predation, pollen feeding (bees [Anthophila] and Masarinae), and eusociality (social vespid wasps, ants, and some bees) [1]. The most well-studied lineages of Aculeata are the ants, which are ecologically dominant in most terrestrial ecosystems [2], and the bees, the most important lineage of angiosperm-pollinating insects [3]...
April 3, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28374596/-management-of-acute-anaphylaxis-in-clinical-practice-in-the-context-of-the-guidelines
#5
P Ch Cmorej, M Nesvadba, R Babeľa, O Slowik, R Didič
Anaphylaxis is a rapidly progressing, life-threatening allergic reaction that needs rapid diagnosis and treatment. Recent research has brought new information about the increasing incidence of anaphylaxis. Nevertheless, the prevalence and incidence of anaphylaxis are difficult to estimate due to the lack of consensus on the definition of anaphylaxis, differences between the population groups analysed, and use of different data collection methods. The most common triggers of anaphylaxis are food allergens, insect stings, and drugs...
2017: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/28372711/outpatient-emergencies-anaphylaxis
#6
REVIEW
Scott P Commins
Anaphylactic fatalities are rare; however, mild reactions can rapidly progress to cardiovascular and respiratory arrest. The clinical course of anaphylaxis can be unpredictable. Prompt and early use of epinephrine should be considered. Most anaphylaxis episodes have an immunologic mechanism involving immunoglobulin E (IgE). Foods are the most common cause in children; medications and insect stings are more common in adults. When the cause is not completely avoidable or cannot be determined, a patient should be supplied with autoinjectable epinephrine and be instructed its use...
May 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/28343967/evolutionary-history-of-the-hymenoptera
#7
Ralph S Peters, Lars Krogmann, Christoph Mayer, Alexander Donath, Simon Gunkel, Karen Meusemann, Alexey Kozlov, Lars Podsiadlowski, Malte Petersen, Robert Lanfear, Patricia A Diez, John Heraty, Karl M Kjer, Seraina Klopfstein, Rudolf Meier, Carlo Polidori, Thomas Schmitt, Shanlin Liu, Xin Zhou, Torsten Wappler, Jes Rust, Bernhard Misof, Oliver Niehuis
Hymenoptera (sawflies, wasps, ants, and bees) are one of four mega-diverse insect orders, comprising more than 153,000 described and possibly up to one million undescribed extant species [1, 2]. As parasitoids, predators, and pollinators, Hymenoptera play a fundamental role in virtually all terrestrial ecosystems and are of substantial economic importance [1, 3]. To understand the diversification and key evolutionary transitions of Hymenoptera, most notably from phytophagy to parasitoidism and predation (and vice versa) and from solitary to eusocial life, we inferred the phylogeny and divergence times of all major lineages of Hymenoptera by analyzing 3,256 protein-coding genes in 173 insect species...
April 3, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28343286/a-mimic-of-sexually-motivated-homicide-insect-stings-and-heat-exhaustion-in-a-forest
#8
Nancy X Liu, Michael S Pollanen
We report the case a woman who was found dead in a forest. The body was nude and the position of the body suggested a sexually motivated homicide. We concluded that death was not related to homicide, but was related to the conjunction of environmental factors, including insect stings, and acute psychosis. A medicolegal death investigation with postmortem examination was undertaken to determine cause of death. At the scene, the body was supine with legs spread apart and the knees flexed, exposing the external genitalia...
March 25, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28270251/decontamination-work-and-the-long-term-increase-in-hospital-visits-for-hymenoptera-stings-following-the-fukushima-nuclear-disaster
#9
Akihiko Ozaki, Takeru Yokota, Shuhei Nomura, Masaharu Tsubokura, Claire Leppold, Tetsuya Tanimoto, Toru Miura, Kana Yamamoto, Toyoaki Sawano, Manabu Tsukada, Masahiro Kami, Yukio Kanazawa, Hiromichi Ohira
OBJECTIVE: Animals, including arthropods, are one health threat that can be affected by disasters. This institution-based study aimed to assess trends in Hymenoptera stings following the 2011 Fukushima nuclear disaster. METHODS: We reviewed the medical records of patients with hymenopteran stings who visited Minamisoma Municipal General Hospital, located 23 km from Fukushima Daiichi Nuclear Power Plant, from March 2005 to March 2016. Patient and sting characteristics of post-disaster patients were examined, and the annual incidence of hospital visits for hymenopteran stings was compared with the pre-disaster baseline, calculating an incidence rate ratio (IRR) for each year...
March 8, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28193791/epinephrine-for-first-aid-management-of-anaphylaxis
#10
Scott H Sicherer, F Estelle R Simons
Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians identify patients at risk of anaphylaxis and new information about epinephrine and epinephrine autoinjectors (EAs). The report also highlights the importance of patient and family education about the recognition and management of anaphylaxis in the community...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28125668/a-new-method-for-quick-and-easy-hemolymph-collection-from-apidae-adults
#11
Grzegorz Borsuk, Aneta A Ptaszyńska, Krzysztof Olszewski, Marcin Domaciuk, Patcharin Krutmuang, Jerzy Paleolog
Bio-analysis of insects is increasingly dependent on highly sensitive methods that require high quality biological material, such as hemolymph. However, it is difficult to collect fresh and uncontaminated hemolymph from adult bees since they are very active and have the potential to sting, and because hemolymph is rapidly melanized. Here we aimed to develop and test a quick and easy method for sterile and contamination-free hemolymph sampling from adult Apidae. Our novel antennae method for hemolymph sampling (AMHS), entailed the detachment of an antenna, followed by application of delicate pressure to the bee's abdomen...
2017: PloS One
https://www.readbyqxmd.com/read/28120601/hymenoptera-venom-allergy-a-closer-collaboration-is-needed-between-allergists-and-emergency-physicians
#12
A Ciccarelli, C Calabrò, C Imperatore, G Scala
Background. Hymenoptera stings are sometimes fatal in venom-allergic patients. Fatalities mostly occur in previously stung subjects, especially those with a history of systemic reactions, and could be avoided if patients were properly informed of the existence of a prevention strategy for insect stings, referred to an allergy follow-up and prescribed auto-injectable epinephrine and/or venom-specific immunotherapy (VIT). We sought to assess knowledge and awareness of Hymenoptera Venom Allergy (HVA) in a small sample of Emergency Physicians in our geographic area...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120424/allergen-immunotherapy-for-insect-venom-allergy-a-systematic-review-and-meta-analysis
#13
REVIEW
S Dhami, H Zaman, E-M Varga, G J Sturm, A Muraro, C A Akdis, D Antolín-Amérigo, M B Bilò, D Bokanovic, M A Calderon, E Cichocka-Jarosz, J N G Oude Elberink, R Gawlik, T Jakob, M Kosnik, J Lange, E Mingomataj, D I Mitsias, H Mosbech, M Ollert, O Pfaar, C Pitsios, V Pravettoni, G Roberts, F Ruëff, B A Sin, M Asaria, G Netuveli, A Sheikh
BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines on Allergen Immunotherapy (AIT) for the management of insect venom allergy. To inform this process, we sought to assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy. METHODS: We undertook a systematic review, which involved searching 15 international biomedical databases for published and unpublished evidence...
November 6, 2016: Allergy
https://www.readbyqxmd.com/read/28050465/lizard-bite-masquerading-as-scorpion-sting-envenomation
#14
Ramesh Neelannavar, Mallanagouda Patil, Shankargouda Patil, Bhavana Lakhkar, Vijaykumar Shegji
Lizard bite is very infrequent in children. Lizards tend to avoid confrontation. Bites are only inflicted when they are manipulated or when they are cornered and feel threatened. Lizard bites may be frightening but most do not cause serious health problems. The wall lizard or gecko, found in most homes, is not poisonous at all. It only checks insect population. A two-year-old boy was brought with history of lizard bite over right hand when he was trying to capture it. The child had experienced excessive sweating and irritability within two hours of bite...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28007086/stinging-insect-hypersensitivity-a-practice-parameter-update-2016
#15
David B K Golden, Jeffrey Demain, Theodore Freeman, David Graft, Michael Tankersley, James Tracy, Joann Blessing-Moore, David Bernstein, Chitra Dinakar, Matthew Greenhawt, David Khan, David Lang, Richard Nicklas, John Oppenheimer, Jay Portnoy, Christopher Randolph, Diane Schuller, Dana Wallace
No abstract text is available yet for this article.
January 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27998634/transient-coagulopathy-due-to-wasp-sting-a-case-report
#16
Jeremy Shaowei Mong, Chee Kheong Ooi
BACKGROUND: Insect venom anaphylaxis is a potentially life-threatening disorder. Transient coagulopathy in insect venom anaphylaxis is a rare phenomenon. CASE REPORT: A 41-year-old man presented to the Emergency Department (ED) with hypotension after a run in a park. History and examination revealed signs of anaphylactic shock. A deranged coagulation profile with a normal platelet count led to the diagnosis of wasp sting anaphylaxis. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Transient deranged coagulation profile with a normal platelet count may arise from insect venom anaphylaxis...
April 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27932918/salix-transect-of-europe-variation-in-ploidy-and-genome-size-in-willow-associated-common-nettle-urtica-dioica-l-sens-lat-from-greece-to-arctic-norway
#17
Quentin Cronk, Oriane Hidalgo, Jaume Pellicer, Diana Percy, Ilia J Leitch
BACKGROUND: The common stinging nettle, Urtica dioica L. sensu lato, is an invertebrate "superhost", its clonal patches maintaining large populations of insects and molluscs. It is extremely widespread in Europe and highly variable, and two ploidy levels (diploid and tetraploid) are known. However, geographical patterns in cytotype variation require further study. NEW INFORMATION: We assembled a collection of nettles in conjunction with a transect of Europe from the Aegean to Arctic Norway (primarily conducted to examine the diversity of Salix and Salix-associated insects)...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27922561/a-pharmacologic-review-of-anaphylaxis
#18
Nancy S Yunker, Bradley J Wagner
Anaphylaxis occurs in the surgical population and may have devastating consequences. Anaphylaxis and anaphylactoid reactions are immediate hypersensitivity reactions that are most commonly precipitated by medications, insect stings, and foods. In the surgical population, 47.4% of immediate hypersensitivity reactions were precipitated by neuromuscular blocking agents, followed by latex and antibiotics in 20% and 18.1% of cases, respectively. Initial treatment consists of removing the precipitating trigger, administering epinephrine, and correct patient positioning...
October 2016: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/27914814/rush-venom-immunotherapy-in-children
#19
Ronit Confino-Cohen, Yossi Rosman, Arnon Goldberg
BACKGROUND: Rush venom immunotherapy (VIT) is highly effective in Hymenoptera venom allergy. Still, specific data regarding its safety and efficiency in children are rather sparse. OBJECTIVES: The objective of this study was to better evaluate the safety and efficiency of rush VIT in this specific age group. METHODS: Children younger than 16 years with systemic reaction to insect sting involving, at least, one body system other than skin and children aged 16-18 years with any kind of systemic reaction were offered conventional or rush VIT with a build-up phase that lasted 3 days...
November 30, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27824940/invertebrate-iridescent-virus-6-a-dna-virus-stimulates-a-mammalian-innate-immune-response-through-rig-i-like-receptors
#20
Laura R H Ahlers, Reginaldo G Bastos, Aoi Hiroyasu, Alan G Goodman
Insects are not only major vectors of mammalian viruses, but are also host to insect-restricted viruses that can potentially be transmitted to mammals. While mammalian innate immune responses to arboviruses are well studied, less is known about how mammalian cells respond to viruses that are restricted to infect only invertebrates. Here we demonstrate that IIV-6, a DNA virus of the family Iridoviridae, is able to induce a type I interferon-dependent antiviral immune response in mammalian cells. Although IIV-6 is a DNA virus, we demonstrate that the immune response activated during IIV-6 infection is mediated by the RIG-I-like receptor (RLR) pathway, and not the canonical DNA sensing pathway via cGAS/STING...
2016: PloS One
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