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https://www.readbyqxmd.com/read/28270251/decontamination-work-and-the-long-term-increase-in-hospital-visits-for-hymenoptera-stings-following-the-fukushima-nuclear-disaster
#1
Akihiko Ozaki, Takeru Yokota, Shuhei Nomura, Masaharu Tsubokura, Claire Leppold, Tetsuya Tanimoto, Toru Miura, Kana Yamamoto, Toyoaki Sawano, Manabu Tsukada, Masahiro Kami, Yukio Kanazawa, Hiromichi Ohira
OBJECTIVE: Animals, including arthropods, are one health threat that can be affected by disasters. This institution-based study aimed to assess trends in Hymenoptera stings following the 2011 Fukushima nuclear disaster. METHODS: We reviewed the medical records of patients with hymenopteran stings who visited Minamisoma Municipal General Hospital, located 23 km from Fukushima Daiichi Nuclear Power Plant, from March 2005 to March 2016. Patient and sting characteristics of post-disaster patients were examined, and the annual incidence of hospital visits for hymenopteran stings was compared with the pre-disaster baseline, calculating an incidence rate ratio (IRR) for each year...
March 8, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28193791/epinephrine-for-first-aid-management-of-anaphylaxis
#2
Scott H Sicherer, F Estelle R Simons
Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians identify patients at risk of anaphylaxis and new information about epinephrine and epinephrine autoinjectors (EAs). The report also highlights the importance of patient and family education about the recognition and management of anaphylaxis in the community...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28125668/a-new-method-for-quick-and-easy-hemolymph-collection-from-apidae-adults
#3
Grzegorz Borsuk, Aneta A Ptaszyńska, Krzysztof Olszewski, Marcin Domaciuk, Patcharin Krutmuang, Jerzy Paleolog
Bio-analysis of insects is increasingly dependent on highly sensitive methods that require high quality biological material, such as hemolymph. However, it is difficult to collect fresh and uncontaminated hemolymph from adult bees since they are very active and have the potential to sting, and because hemolymph is rapidly melanized. Here we aimed to develop and test a quick and easy method for sterile and contamination-free hemolymph sampling from adult Apidae. Our novel antennae method for hemolymph sampling (AMHS), entailed the detachment of an antenna, followed by application of delicate pressure to the bee's abdomen...
2017: PloS One
https://www.readbyqxmd.com/read/28120601/hymenoptera-venom-allergy-a-closer-collaboration-is-needed-between-allergists-and-emergency-physicians
#4
A Ciccarelli, C Calabrò, C Imperatore, G Scala
Background. Hymenoptera stings are sometimes fatal in venom-allergic patients. Fatalities mostly occur in previously stung subjects, especially those with a history of systemic reactions, and could be avoided if patients were properly informed of the existence of a prevention strategy for insect stings, referred to an allergy follow-up and prescribed auto-injectable epinephrine and/or venom-specific immunotherapy (VIT). We sought to assess knowledge and awareness of Hymenoptera Venom Allergy (HVA) in a small sample of Emergency Physicians in our geographic area...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28120424/allergen-immunotherapy-for-insect-venom-allergy-a-systematic-review-and-meta-analysis
#5
REVIEW
S Dhami, H Zaman, E-M Varga, G J Sturm, A Muraro, C A Akdis, D Antolín-Amérigo, M B Bilò, D Bokanovic, M A Calderon, E Cichocka-Jarosz, J N G Oude Elberink, R Gawlik, T Jakob, M Kosnik, J Lange, E Mingomataj, D I Mitsias, H Mosbech, M Ollert, O Pfaar, C Pitsios, V Pravettoni, G Roberts, F Ruëff, B A Sin, M Asaria, G Netuveli, A Sheikh
BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines on Allergen Immunotherapy (AIT) for the management of insect venom allergy. To inform this process, we sought to assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy. METHODS: We undertook a systematic review, which involved searching 15 international biomedical databases for published and unpublished evidence...
November 6, 2016: Allergy
https://www.readbyqxmd.com/read/28050465/lizard-bite-masquerading-as-scorpion-sting-envenomation
#6
Ramesh Neelannavar, Mallanagouda Patil, Shankargouda Patil, Bhavana Lakhkar, Vijaykumar Shegji
Lizard bite is very infrequent in children. Lizards tend to avoid confrontation. Bites are only inflicted when they are manipulated or when they are cornered and feel threatened. Lizard bites may be frightening but most do not cause serious health problems. The wall lizard or gecko, found in most homes, is not poisonous at all. It only checks insect population. A two-year-old boy was brought with history of lizard bite over right hand when he was trying to capture it. The child had experienced excessive sweating and irritability within two hours of bite...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28007086/stinging-insect-hypersensitivity-a-practice-parameter-update-2016
#7
David B K Golden, Jeffrey Demain, Theodore Freeman, David Graft, Michael Tankersley, James Tracy, Joann Blessing-Moore, David Bernstein, Chitra Dinakar, Matthew Greenhawt, David Khan, David Lang, Richard Nicklas, John Oppenheimer, Jay Portnoy, Christopher Randolph, Diane Schuller, Dana Wallace
No abstract text is available yet for this article.
January 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27998634/transient-coagulopathy-due-to-wasp-sting-a-case-report
#8
Jeremy Shaowei Mong, Chee Kheong Ooi
BACKGROUND: Insect venom anaphylaxis is a potentially life-threatening disorder. Transient coagulopathy in insect venom anaphylaxis is a rare phenomenon. CASE REPORT: A 41-year-old man presented to the Emergency Department (ED) with hypotension after a run in a park. History and examination revealed signs of anaphylactic shock. A deranged coagulation profile with a normal platelet count led to the diagnosis of wasp sting anaphylaxis. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Transient deranged coagulation profile with a normal platelet count may arise from insect venom anaphylaxis...
December 17, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27932918/salix-transect-of-europe-variation-in-ploidy-and-genome-size-in-willow-associated-common-nettle-urtica-dioica-l-sens-lat-from-greece-to-arctic-norway
#9
Quentin Cronk, Oriane Hidalgo, Jaume Pellicer, Diana Percy, Ilia J Leitch
BACKGROUND: The common stinging nettle, Urtica dioica L. sensu lato, is an invertebrate "superhost", its clonal patches maintaining large populations of insects and molluscs. It is extremely widespread in Europe and highly variable, and two ploidy levels (diploid and tetraploid) are known. However, geographical patterns in cytotype variation require further study. NEW INFORMATION: We assembled a collection of nettles in conjunction with a transect of Europe from the Aegean to Arctic Norway (primarily conducted to examine the diversity of Salix and Salix-associated insects)...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27922561/a-pharmacologic-review-of-anaphylaxis
#10
Nancy S Yunker, Bradley J Wagner
Anaphylaxis occurs in the surgical population and may have devastating consequences. Anaphylaxis and anaphylactoid reactions are immediate hypersensitivity reactions that are most commonly precipitated by medications, insect stings, and foods. In the surgical population, 47.4% of immediate hypersensitivity reactions were precipitated by neuromuscular blocking agents, followed by latex and antibiotics in 20% and 18.1% of cases, respectively. Initial treatment consists of removing the precipitating trigger, administering epinephrine, and correct patient positioning...
October 2016: Plastic Surgical Nursing
https://www.readbyqxmd.com/read/27914814/rush-venom-immunotherapy-in-children
#11
Ronit Confino-Cohen, Yossi Rosman, Arnon Goldberg
BACKGROUND: Rush venom immunotherapy (VIT) is highly effective in Hymenoptera venom allergy. Still, specific data regarding its safety and efficiency in children are rather sparse. OBJECTIVES: The objective of this study was to better evaluate the safety and efficiency of rush VIT in this specific age group. METHODS: Children younger than 16 years with systemic reaction to insect sting involving, at least, one body system other than skin and children aged 16-18 years with any kind of systemic reaction were offered conventional or rush VIT with a build-up phase that lasted 3 days...
November 30, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27824940/invertebrate-iridescent-virus-6-a-dna-virus-stimulates-a-mammalian-innate-immune-response-through-rig-i-like-receptors
#12
Laura R H Ahlers, Reginaldo G Bastos, Aoi Hiroyasu, Alan G Goodman
Insects are not only major vectors of mammalian viruses, but are also host to insect-restricted viruses that can potentially be transmitted to mammals. While mammalian innate immune responses to arboviruses are well studied, less is known about how mammalian cells respond to viruses that are restricted to infect only invertebrates. Here we demonstrate that IIV-6, a DNA virus of the family Iridoviridae, is able to induce a type I interferon-dependent antiviral immune response in mammalian cells. Although IIV-6 is a DNA virus, we demonstrate that the immune response activated during IIV-6 infection is mediated by the RIG-I-like receptor (RLR) pathway, and not the canonical DNA sensing pathway via cGAS/STING...
2016: PloS One
https://www.readbyqxmd.com/read/27753590/stinging-the-conscience-a-case-of-severe-hymenoptera-anaphylaxis-and-the-need-for-provider-awareness
#13
Kyle Mikals, Douglas Beakes, Taylor A Banks
Hymenoptera venom allergy accounts for approximately 17% of all cases of anaphylaxis. Insect stings are a common occurrence across the world, with significant impact on active duty personnel. Venom immunotherapy (VIT) provides an effective treatment for those with systemic reactions to insect stings and other similar indications. We present a case of severe reaction to hymenoptera venom requiring an epinephrine drip and provide an overview for primary care providers on who should be referred to allergy or an allergist, carry an epinephrine auto-injector, and be a candidate for VIT...
October 2016: Military Medicine
https://www.readbyqxmd.com/read/27685197/follow-up-of-venom-immunotherapy-on-flow-cytometry-and-definition-of-a-protective-index
#14
Jean Sainte-Laudy, François Touraine, Delphine Cluzan, François Belle Moudourou
BACKGROUND: A major problem of venom-specific immunotherapy (VIT) is the absence of reliable parameters for deciding treatment discontinuation. AIM OF THE STUDY: Intracutaneous tests (ICTs), the basophil activation test (BAT), specific IgEs (sIgEs) and blocking factor (BF) activity were measured during VIT. We made an evaluation by means of a protective index (PI) including ICT, BAT and BF values. MATERIAL AND METHODS: A population of 45 patients who had experienced a systemic reaction after an insect sting were tested before VIT (T0), at 1 week (T1w), at 10 weeks (T10w) and at 21 weeks (T21w), and, for a subgroup of 17 patients, at 3-5 years (T3-5y)...
2016: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/27591992/insect-sting-reactions-and-specific-ige-to-venom-and-major-allergens-in-a-general-population
#15
Holger Mosbech, Line Tang, Allan Linneberg
BACKGROUND: Insect sting reactions are frequently reported, but population studies documenting the frequency and the relation to IgE-sensitization and serum tryptase are scarce. METHODS: Questionnaire data and results from measurements of specific IgE against venom, major allergens and cross-reacting carbohydrate determinants (CCDs) were collected from 2,090 adult participants in a cross-sectional survey. RESULTS: 13% of the population reported symptoms of sting reactions and about half were systemic in nature...
2016: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/27545732/insect-allergy
#16
REVIEW
Hobart Lee, Sara Halverson, Regina Mackey
Insect bites and stings are common. Risk factors are mostly associated with environmental exposure. Most insect bites and stings result in mild, local, allergic reactions. Large local reactions and systemic reactions like anaphylaxis are possible. Common insects that bite or sting include mosquitoes, ticks, flies, fleas, biting midges, bees, and wasps. The diagnosis is made clinically. Identification of the insect should occur when possible. Management is usually supportive. For anaphylaxis, patients should be given epinephrine and transported to the emergency department for further evaluation...
September 2016: Primary Care
https://www.readbyqxmd.com/read/27545728/allergy-testing
#17
REVIEW
Konstantinos Tourlas, Deepa Burman
Allergic diseases are common in outpatient primary care. Allergy testing can guide management to determine allergy as a cause of symptoms and target therapeutic interventions. This article provides a review of common methods of allergy testing available so that physicians may counsel and refer patients appropriately. Immediate-type hypersensitivity skin tests can be used for airborne allergens, foods, insect stings, and penicillin. Radioallergosorbent testing can be used to evaluate immediate-type hypersensitivity...
September 2016: Primary Care
https://www.readbyqxmd.com/read/27544632/bothriurus-bonariensis-scorpion-venom-activates-voltage-dependent-sodium-channels-in-insect-and-mammalian-nervous-systems
#18
Douglas Silva Dos Santos, Evelise Leis Carvalho, Jeferson Camargo de Lima, Ricardo Vaz Breda, Raquel Soares Oliveira, Thiago Carrazoni de Freitas, Simone Denise Salamoni, Michelle Flores Domingues, Angela Regina Piovesan, Juliano Tomazzoni Boldo, Dênis Reis de Assis, Jaderson Costa da Costa, Cháriston André Dal Belo, Paulo Marcos Pinto
Animal venoms have been widely recognized as a major source of biologically active molecules. Bothriurus bonariensis, popularly known as black scorpion, is the arthropod responsible for the highest number of accidents involving scorpion sting in Southern Brazil. Here we reported the first attempt to investigate the neurobiology of B. bonariensis venom (BBV) in the insect and mammalian nervous system. BBV (32 μg/g) induced a slow neuromuscular blockade in the in vivo cockroach nerve-muscle preparations (70 ± 4%, n = 6, p < 0...
October 25, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27505851/-not-available
#19
Theo Gülen, Janne Björkander
Bee and wasp stings can cause allergic reactions. Although the local reactions are more frequent, anaphylaxis due to insect stings can be potentially fatal. Rapid recognition of anaphylaxis is therefore critical and reactions should immediately be treated with i.m. adrenaline. Patients having experienced anaphylaxis should be referred to an allergist for diagnostic evaluation and possible venom-immunotherapy (VIT). The clinical history is essential in diagnosis of venom allergy as the test results are not always reliable...
August 4, 2016: Läkartidningen
https://www.readbyqxmd.com/read/27496543/application-of-recombinant-antigen-5-allergens-from-seven-allergy-relevant-hymenoptera-species-in-diagnostics
#20
M Schiener, B Eberlein, C Moreno-Aguilar, G Pietsch, P Serrano, M McIntyre, L Schwarze, D Russkamp, T Biedermann, E Spillner, U Darsow, M Ollert, C B Schmidt-Weber, S Blank
BACKGROUND: Hymenoptera stings can cause severe anaphylaxis in untreated venom-allergic patients. A correct diagnosis regarding the relevant species for immunotherapy is often hampered by clinically irrelevant cross-reactivity. In vespid venom allergy, cross-reactivity between venoms of different species can be a diagnostic challenge. To address immunological IgE cross-reactivity on molecular level, seven recombinant antigens 5 of the most important Vespoidea groups were assessed by different diagnostic setups...
January 2017: Allergy
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