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https://www.readbyqxmd.com/read/28938365/why-the-p-value-alone-is-not-enough-the-need-for-confidence-intervals-in-plastic-surgery-research
#1
Osama A Samargandi, Mona Al-Taha, Kit Moran, Sarah Al Youha, Michael Bezuhly
BACKGROUND: The p-value is one of the most utilized descriptors in statistical analysis; however, when reported in isolation, it does not convey the effect size of a treatment. The reporting of confidence intervals (CIs) is an essential adjunct to determine the clinical value of treatment, as it permits an assessment of the effect size. The authors assessed the reporting of CIs in clinical trials within the plastic surgery literature. METHODS: The seven highest impact plastic surgery journals were screened using MEDLINE for clinical trials in the years 2006, 2009, 2012, and 2015...
September 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28937899/microbiological-evaluation-of-ozone-on-dentinal-lesions-in-young-permanent-molars-using-the-stepwise-excavation
#2
Osama Safwat, Mona Elkateb, Karin Dowidar, Hala Abdel Salam, Omar El Meligy
AIM: To assess the microbial effect of ozone gas on dentinal lesions in young permanent molars using the stepwise excavation. STUDY DESIGN: An experimental, controlled clinical trial was performed. The sample included 80 immature first permanent molars, showing deep occlusal carious cavities that were indicated for stepwise excavation. Following first step of dentin excavation, the sample was divided into test (ozone gas) and control (calcium hydroxide (Ca(OH)2) base material) groups...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28937889/clinical-evaluation-of-ozone-on-dentinal-lesions-in-young-permanent-molars-using-the-stepwise-excavation
#3
Osama Safwat, Mona Elkateb, Karin Dowidar, Omar El Meligy
AIM: To evaluate the clinical changes in dentin of deep carious lesions in young permanent molars, following ozone application with and without the use of a remineralizing solution, using the stepwise excavation. STUDY DESIGN: The sample included 162 first permanent immature molars, showing deep occlusal carious cavities that were indicated for indirect pulp capping. Teeth were divided into 2 main groups according to the method of ozone treatment. Each group was further subdivided equally into test and control subgroups...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28937536/enoxaparin-population-pharmacokinetics-in-the-first-year-of-life
#4
Brady S Moffett, Marianne Galati, Donald Mahoney, YoungNa Lee-Kim, Jun Teruya, Mona D Shah, Donald L Yee
Aims Enoxaparin dosing requirements in the first year of life can be highly variable. Characterization of pharmacokinetics in this patient population can assist in dosing. METHODS: Patients less than one year post-natal age who received enoxaparin and had an anti-factor Xa activity level drawn as inpatients were identified through the pharmacy database over a five-year period. Patients on renal replacement therapy or with hyperbilirubinemia were excluded. Data collection included demographic variables, indication for enoxaparin, enoxaparin doses, anti-factor Xa activity levels, serum creatinine, hemoglobin, hematocrit, platelet count, and urine output over the previous 24 hours...
September 19, 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/28937439/langerhans-cell-histiocytosis-with-clinical-and-histologic-features-of-hidradenitis-suppurativa-brief-report-and-review
#5
Jessica E Kalen, Divya Shokeen, Mona Mislankar, Michael Wangia, Kiran Motaparthi
Langerhans cell histiocytosis (LCH) is an uncommon histiocytic disorder in adults. Clinically, this rare entity can mimic other dermatologic conditions, including hidradenitis suppurativa. A case of LCH is reported with clinical and histologic features of hidradenitis suppurativa, along with a review of these unusual findings. Clinical dermatologists and dermatopathologists benefit from awareness of this unique presentation, which may prompt earlier identification and diagnosis of adult patients with LCH.
September 11, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28937024/celiac-disease-related-osteopathy-among-saudi-celiac-patients-are-we-adherent-to-recommendations
#6
Mona A Fouda
BACKGROUND/AIMS: There are no reports from Saudi Arabia documenting the picture of osteopathy in celiac disease (CD) and the adherence of physicians to the guidelines and recommendations to screen for bone disease. We conducted this study to document the prevalence of CD-related osteopathy and the Saudi physicians' adherence to the screening recommendations. PATIENTS AND METHODS: We identified the biopsy proven CD cases diagnosed between 2003 and 2012. In addition to demographic data, we collected laboratory (serum calcium, phosphate, alkaline phosphatase, 25-dihydroxy vitamin D, and parathyroid hormone levels) and imaging [Dual-energy X-ray absorptiometry (DEXA)] data...
September 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28936188/all-impostors-aren-t-alike-differentiating-the-impostor-phenomenon
#7
Mona Leonhardt, Myriam N Bechtoldt, Sonja Rohrmann
Following up on earlier investigations, the present paper analyzes construct validity of the impostor phenomenon. It examines the question whether the impostor phenomenon is a homogeneous construct or whether different types of persons with impostor self-concept can be distinguished on the basis of related characteristics. The study was conducted with professionals in leadership positions exhibiting a pronounced impostor self-concept (n = 183). Cluster-analytic procedures indicated the existence of two different types: one group which, in line with the literature (e...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28935805/teaching-personal-initiative-beats-traditional-training-in-boosting-small-business-in-west-africa
#8
Francisco Campos, Michael Frese, Markus Goldstein, Leonardo Iacovone, Hillary C Johnson, David McKenzie, Mona Mensmann
Standard business training programs aim to boost the incomes of the millions of self-employed business owners in developing countries by teaching basic financial and marketing practices, yet the impacts of such programs are mixed. We tested whether a psychology-based personal initiative training approach, which teaches a proactive mindset and focuses on entrepreneurial behaviors, could have more success. A randomized controlled trial in Togo assigned microenterprise owners to a control group (n = 500), a leading business training program (n = 500), or a personal initiative training program (n = 500)...
September 22, 2017: Science
https://www.readbyqxmd.com/read/28935409/-which-technique-should-be-used-in-the-phenotyping-of-lymphocytic-alveolitis-immunocytochemistry-or-flow-cytometry
#9
Mona Mlika, Rihem Kasmi, Ines Safra, Emna Braham, Chokri Chebbi, Faouzi El Mezni
BACKGROUND: Diffuse interstitial pneumonias are considered as a group of multiple affections characterized by challenging diagnoses because of the lack of specific clinical signs. Radiologic investigations highlight the diagnoses in most of the cases but bronchoalveolar lavage plays a key role in the diagnostic diagram. We aim to compare the immunocytochemical technique and the flow cytometry in the phenotyping of lymphocytic alveolitis. METHODS: We described a series of 32 lymphocytic alveolitis, which were analyzed using immunocytochemistry and flow cytometry...
September 18, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28935257/tetrac-conjugated-polymersomes-for-integrin-targeted-delivery-of-camptothecin-to-colon-adenocarcinoma-in-vitro-and-in-vivo
#10
Mona Alibolandi, Rouhollah Rezvani, Sara Amel Farzad, Seyed Mohammad Taghdisi, Khalil Abnous, Mohammad Ramezani
In this study, we prepared tetraiodothyroacetic acid (tetrac) conjugated PEG-PLGA polymersomes for the targeted delivery of camptothecin to colon adenocarcinoma. Tetrac, which binds to integrin αvβ3 with high affinity and specificity, was covalently conjugated to the surface of the PEGylated polymersomal formulation of camptothecin (CPT). The hydrodynamic and morphological properties of the prepared system were evaluated using TEM (transmission electron microscopy), SEM (scanning electron microscopy) and DLS (dynamic light scattering) experiments...
September 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28934183/trends-in-cervical-cancer-screening-in-title-x-funded-health-centers-united-states-2005-2015
#11
Christina I Fowler, Mona Saraiya, Susan B Moskosky, Jacqueline W Miller, Julia Gable, Nancy Mautone-Smith
Cervical cancer screening is critical to early detection and treatment of precancerous cells and cervical cancer. In 2015, 83% of U.S. women reported being screened per current recommendations, which is below the Healthy People 2020 target of 93% (1,2). Disparities in screening persist for women who are younger (aged 21-30 years), have lower income, are less educated, are uninsured, lack a source of health care, or who self-identify as Asian or American Indian/Alaska Native (2). Women who are never screened or rarely screened are more likely to develop cancer and receive a cancer diagnosis at later stages than women who are screened regularly (3)...
September 22, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28933743/european-policies-to-promote-children-s-rights-and-combat-child-poverty
#12
Mona Sandbæk
The upbringing of children relies heavily on shared responsibilities between parents and society. The Council of Europe Recommendation (2006) 19 on Policy to Support Positive Parenting and the European Commission Recommendation (2013) Investing in Children: Breaking the Cycle of Disadvantage, both aim at supporting parents to care and provide for their children in accordance with the UN Convention on the Rights of the Child. By means of a document analysis this article examines what kind of parental practices and provision to parents the recommendations suggest to safeguard children's rights in the family...
July 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28933691/jaminaea-pallidilutea-sp-nov-microstromatales-a-basidiomycetous-yeast-isolated-from-plant-material-of-mangrove-forests-in-iran
#13
Shaghayegh Nasr, Mona Mohammadimehr, Marzieh Geranpayeh Vaghei, Mohammad Ali Amoozegar, Seyed Abolhassan Shahzadeh Fazeli, Andrey Yurkov
In the course of an ongoing study aiming to catalogue the natural yeast biodiversity of Iran, a number of yeasts were isolated from plant material collected from mangrove forests on the shoreline of Qeshm Island. Two strains were identified as members of order Microstromatales. Standard phenotypic, biochemical, physiological characterization and a phylogenetic analyses of the combined 26S rRNA gene (D1/D2 domains) and ITS region sequences showed the conspecificity of these isolates and suggest their placement in the genus Jaminaea, close to Jaminaea lanaiensis and Jaminaea angkoriensis...
September 21, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28932329/molecular-characterization-of-klebsiella-pneumoniae-clinical-isolates-with-elevated-resistance-to-carbapenems
#14
Rasha Barwa, Mona Shaaban
BACKGROUND: Emergence of carbapenems-resistant K. pneumoniae represents a serious challenge for antimicrobial therapy. OBJECTIVE: The aim of this research is to determine different mechanisms mediating the emergence of K. pneumoniae isolates with high-level carbapenem resistance. METHOD: A total of 80 K. pneumoniae isolates were purified from sputum and urine specimens. The minimum inhibitory concentrations (MICs) of imipenem and meropenem were determined by broth microdilution method...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/28932298/expression-of-hnrnpk-claudin-4-in-hcv-induced-early-hcc-and-adjacent-liver-tissue
#15
Olfat Hammam, Mona Magdy, Amgad Anas, Ali Abdel Rahim, Mohamed Heedaya, Ahmed Helmy
BACKGROUND: HCC in Egypt usually occurs in HCV cirrhotic livers with poor prognosis due to late diagnosis. High hnRNPK & low Claudin-4 profiles indicate Epithelial Mesenchymal Transition (EMT), malignant transformation and high-grade tumours. AIM: We studied the immunohistochemical expression of hnRNPK and Claudin-4 in HCV induced early HCC (eHCC) and adjacent liver tissue in Egyptian patients to improve eHCC detection in cirrhotic livers with better curative therapy options...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932295/expression-of-mdm2-mrna-mdm2-p53-and-p16-proteins-in-urothelial-lesions-in-the-view-of-the-who-4-th-edition-guidelines-as-a-molecular-insight-towards-personalized-medicine
#16
Olfat Hammam, Mona Magdy, Mohamed Badawy, Khalid Al Osili, Amr El Kholy, Tarek El LeitHy
AIM: Here we imposed a multimarker molecular panel composed of P53, MDM2 protein & mRNA & P16 with the identification of sensitive and specific cut offs among the Egyptian urothelial carcinomas bilharzial or not emphasize the pathological and molecular classifications, pathways and prognosis as a privilege for adjuvant therapy. METHODS: Three hundred and ten urothelial lesions were pathologically evaluated and grouped as follows: 50 chronic cystitis as benign, 240 urothelial carcinomas and 20 normal bladder tissue as a control...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932161/the-efficacy-of-a-diabetic-educational-program-and-predictors-of-compliance-of-patients-with-noninsulin-dependent-type-2-diabetes-mellitus-in-al-khobar-saudi-arabia
#17
Fatma M Mokabel, Shadia F Aboulazm, Hanan E Hassan, Mona F Al-Qahtani, Seham F Alrashedi, Fatma A Zainuddin
BACKGROUND: The concept of detection and management of diabetes mellitus at primary health-care centers is justified and widely practised in Saudi Arabia. The objective of this study was to assess the efficacy of diabetic educational programs for noninsulin-dependent (type 2) diabetes mellitus patients, and to determine the predictors of compliance. MATERIALS AND METHODS: A longitudinal experimental research design was adopted for this study and conducted at the diabetic outpatient clinic of King Fahd Hospital of the University, Al Khobar, Kingdom of Saudi Arabia...
September 2017: Journal of Family & Community Medicine
https://www.readbyqxmd.com/read/28932142/color-stability-and-marginal-integrity-of-interim-crowns-an-in-vitro-study
#18
Marwa I Elagra, Mohammad R Rayyan, Maisam M Alhomaidhi, Areej A Alanaziy, Mona O Alnefaie
OBJECTIVE: Many commercial dental materials are used to fabricate interim restorations. This study aimed to compare the color stability and the marginal integrity of four different interim crown materials. MATERIALS AND METHODS: An ivorine right maxillary central incisor was prepared for a full coverage all-ceramic restoration. A total of 36 specimens in the form of crowns were fabricated on the master die using four different materials (n = 9); Polymethyl methacrylate (PMMA) resin (TrimPLUS), PMMA computer-aided design, and computer-aided manufacturing (CAD-CAM) blocks (Ceramill TEMP), cold cure bis-acryl resin (Success CD), and bis-acryl resin dual-cure composite (TempSpan)...
July 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28931384/early-food-for-future-health-a-randomized-controlled-trial-evaluating-the-effect-of-an-ehealth-intervention-aiming-to-promote-healthy-food-habits-from-early-childhood
#19
Christine Helle, Elisabet Rudjord Hillesund, Mona Linge Omholt, Nina Cecilie Øverby
BACKGROUND: Childhood overweight and obesity is a global public health challenge. Primary prevention initiatives targeting parents have been called for to encourage a positive feeding environment and healthy eating habits that may lay a good foundation for future health. At the same time, there is a need for interventions which combine accessibility and scalability with cost effectiveness. Today's parents are extensive Internet-users, but only a few randomized controlled trials have investigated the use of Internet to promote healthy eating habits in early childhood...
September 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28931368/depression-differed-by-midnight-cortisol-secretion-alexithymia-and-anxiety-between-diabetes-types-a-cross-sectional-comparison
#20
Eva O Melin, Maria Thunander, Mona Landin-Olsson, Magnus Hillman, Hans O Thulesius
BACKGROUND: Increased prevalence of depression is found in both type 2 diabetes (T2D) and type 1 diabetes (T1D). Melancholia and atypical depression differ by cortisol secretion and clinical features. The aim was to compare the clinical presentation of T1D and T2D patients in relation to self-reported depression, self-reported anxiety, alexithymia, obesity, and midnight salivary cortisol (MSC). METHODS: Comparative cross-sectional design. The participants were consecutively recruited from one hospital diabetes outpatient clinic: 24 T2D patients (31-59 years) and 148 T1D patients (32-59 years)...
September 20, 2017: BMC Psychiatry
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