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https://www.readbyqxmd.com/read/29165955/male-caregivers-of-persons-with-end-stage-renal-disease-a-qualitative-study
#1
Loretta Alexia Williams, J Carolyn Graff, Mona N Wicks, Patricia A Cowan, Shelley White-Means, Elizabeth A Tolley
This study explored experiences associated with burden, depressive symptoms, and perceived health in six male caregivers of persons with end stage renal disease (ESRD) using qualitative interviews. Analysis employed open coding and analysis to generate codes and categories. Eighty-three percent of the participants reported significant subjective and objective burden. Linkages occurred between sociodemographic characteristics, care recipient attributes, and caregiver-care recipient relationship, and caregivers' experience of burden and depressive symptoms...
May 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29163943/rehabilitation-for-patients-with-rheumatic-diseases-patient-experiences-of-a-structured-goal-planning-and-tailored-follow-up-programme
#2
Turid Nygaard Dager, Ingvild Kjeken, Gunnhild Berdal, Anne-Lene Sand-Svartrud, Ingvild Bø, Anne Dingsør, Siv Grødal Eppeland, Jon Hagfors, Bente Hamnes, Merete Nielsen, Bente Slungaard, Sigrid Hørven Wigers, Mona-Iren Hauge
Objective: To explore the significance of the content of rehabilitation in terms of achieving a personal outcome, and to understand the significance of tailored follow-up interventions for individual efforts to prolong health behaviour change after rehabilitation. Design: Semi-structured interviews with patients who had received an extended rehabilitation programme. All interviews were transcribed verbatim. A thematic analysis was applied. Subjects: A purposeful sample of 18 patients with rheumatic diseases who had attended specialized multidisciplinary rehabilitation with an extended programme consisting of a self-help booklet, structured goal-setting talks and tailored follow-up calls based on motivational interviewing...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/29163198/ankyrins-and-spectrins-in-cardiovascular-biology-and-disease
#3
REVIEW
Mona M El Refaey, Peter J Mohler
Ankyrins are adaptor proteins critical for the expression and targeting of cardiac membrane proteins, signaling molecules, and cytoskeletal elements. Findings in humans and animal models have highlighted the in vivo roles for ankyrins in normal physiology and in cardiovascular disease, most notably in cardiac arrhythmia. For example, human ANK2 loss-of-function variants are associated with a complex array of electrical and structural phenotypes now termed "ankyrin-B syndrome," whereas alterations in the ankyrin-G pathway for Nav channel targeting are associated with human Brugada syndrome...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29161778/highly-efficient-destruction-of-squamous-carcinoma-cells-of-the-head-and-neck-by-photochemical-internalization-of-ranpirnase
#4
Nora Liebers, Tim Holland-Letz, Mona Welschof, Anders Høgset, Dirk Jäger, Michaela A E Arndt, Jürgen Krauss
Introduction: Photochemical Internalization is a novel drug delivery technology for cancer treatment based on the principle of Photodynamic Treatment. Using a photosensitizer that locates in endocytic vesicles membranes of tumor cells, Photochemical internalization enables cytosolic release of endocytosed antitumor agents in a site-specific manner. The purpose of the present in-vitro study was to explore whether Photochemical Internalization is able to enhance the efficacy of Ranpirnase, a cytotoxic amphibian ribonuclease, for eradication of squamous cell carcinoma of the head and neck...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29158881/serum-proteomic-profiling-of-obsessive-compulsive-disorder-washing-subtype-a-preliminary-study
#5
Mona Zamanian-Azodi, Mostafa Rezaei-Tavirani, Naser Nejadi, Afsaneh Arefi Oskouie, Faird Zayeri, Mostafa Hamdieh, Akram Safaei, Majid Rezaei-Tavirani, Alireza Ahmadzadeh, Alireza Amouzandeh-Nobaveh, Farshad Okhovatian
Introduction: Obsessive-Compulsive Disorder (OCD) is a disabling mental condition that its proteomic profiling is not yet investigated. Proteomics is a valuable tool to discover biomarker approaches. It can be helpful to detect protein expression changes in complex disorders such as OCD. Methods: Here, by the application of 2D gel electrophoresis (2DE), a pilot study of serum proteome profile of females with washing subtype of OCD was performed. Serum samples were obtained from females with washing subtype of OCD...
July 2017: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29158661/policy-system-and-environmental-correlates-of-fruit-and-vegetable-consumption-in-a-low-income-african-american-population-in-the-southeast
#6
Lori Brand Bateman, LaToya J O'Neal, Theolishia Smith, Yufeng Li, Theresa A Wynn, Chen Dai, Mona N Fouad
Objective: The current study seeks to identify policy, system and environmental (PSE) correlates of fruit and vegetable consumption among a sample of low-income African Americans in two counties in Alabama (Jefferson and Mobile) and one county in Mississippi (Forrest). Design: A modified Behavioral Risk Factor Surveillance System (BRFFS) survey, which included multi-level ecological factors, was used to evaluate nutritional habits at the pre-intervention stage of a multi-state research study...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29158660/empowering-one-community-at-a-time-for-policy-system-and-environmental-changes-to-impact-obesity
#7
Katrina Betancourt, Andrea Ridgway, Joy Rockenbach, Sequoya Eady, Joanice Thompson, Lori Brand Bateman, Mona N Fouad, Yu-Mei M Schoenberger
Objective: This article describes Mayors Mentoring Mayors (3M), an initiative of the Arkansas Coalition for Obesity Prevention (ArCOP), which expanded to five states to become the signature community initiative of the Mid-South Transdisciplinary Collaborative Center (Mid-South TCC) for Health Disparities Research. Methods: The 3M program is an extension of the Growing Healthy Communities (GHC) program, which sought to build capacity within communities to reduce obesity by implementing policy, system and environmental (PSE) changes that support healthy living...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29158658/examining-neighborhood-social-cohesion-in-the-context-of-community-based-participatory-research-descriptive-findings-from-an-academic-community-partnership
#8
Lori Brand Bateman, Mona N Fouad, Bianca Hawk, Tiffany Osborne, Sejong Bae, Sequoya Eady, Joanice Thompson, Wendy Brantley, Lovie Crawford, Laura Heider, Yu-Mei M Schoenberger
Objective: The purpose of this article is to describe the process of conducting an assessment of neighborhood perceptions and cohesion by a community coalition-academic team created in the context of community-based participatory research (CBPR), to guide the design of locally relevant health initiatives. Methods: Guided by CBPR principles, a collaborative partnership was established between an academic center and a local, urban, underserved neighborhood in Birmingham, Alabama to identify and address community concerns and priorities...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29158655/bikeshare-use-in-urban-communities-individual-and-neighborhood-factors
#9
Gabriela R Oates, Bryant W Hamby, Sejong Bae, Maria C Norena, H Olivia Hart, Mona N Fouad
Objective: Bicycling is an affordable way to increase access to employment, schooling, and services and an effective measure against obesity. Bikeshare programs can make bicycling accessible to diverse populations, but little evidence exists on their adoption in low-resource neighborhoods. Our study examined factors associated with bikeshare use in a metropolitan area in the southern United States. Methods: We performed a retrospective cross-sectional analysis of a database of clients (N=815) who rented a bicycle from Zyp Bikeshare in Birmingham, Alabama between October 2015 and November 2016...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29157166/sub-chronic-boldine-treatment-exerts-anticonvulsant-effects-in-mice
#10
Leila Moezi, Siranoush Yahosseini, Akram Jamshidzadeh, Mona Dastgheib, Fateme Pirsalami
OBJECTIVES: Boldine is an aporphine alkaloid which is best known for its antioxidant, anti-inflammatory and cytoprotective characteristics. It seems that all these activities are related to boldine ability to scavenge reactive free radicals. As indicated by several pieces of evidence, free radicals generation are involved in initiation and propagation of epilepsy. METHODS: In this study, we investigated the sub-chronic effects of boldine on intraperitoneal and intravenous pentylenetetrazole (PTZ) models and electroshock-induced seizure in mice...
November 20, 2017: Neurological Research
https://www.readbyqxmd.com/read/29156489/an-adherent-mucus-layer-attenuates-the-genotoxic-effect-of-colibactin
#11
Christian Reuter, Mona Alzheimer, Heike Walles, Tobias A Oelschlaeger
The human gastrointestinal tract is a complex ecosystem in which epithelial cells and microorganisms of the intestinal microbiota live in symbiosis. Certain members of the microbiota, in particular Escherichia coli strains of the B2 phylotype, carry the polyketide synthase (pks)-island encoding the genotoxin colibactin. Colibactin is a non-ribosomal peptide (NRP) or polyketide (PK)-NRP hybrid of still unsolved structure, which induces DNA double strand breaks (DSBs) in eukaryotic cells. However, direct contact between live bacteria and host cell is required in order to elicit these genotoxic effects...
November 20, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/29156408/label-free-electrochemical-dna-biosensor-for-guanine-and-adenine-by-ds-dna-poly-l-cysteine-fe3o4-nanoparticles-graphene-oxide-nanocomposite-modified-electrode
#12
Majid Arvand, Mona Sanayeei, Shiva Hemmati
In this study, we aim to design a simple and effective electrochemical DNA biosensor based on a carbon paste electrode modified with ds-DNA/poly(L-cysteine)/Fe3O4 nanoparticles-graphene oxide (ds-DNA/p(L-Cys)/Fe3O4 NPs-GO/CPE) for sensitive detection of adenine (A) and guanine (G). The electrocatalytic oxidation of A and G on the electrode was explored by differential pulse voltammetry (DPV) and cyclic voltammetry (CV). This sensor shows separated and well-defined peaks for A and G, by which one can determine these biological bases individually or simultaneously...
November 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29155666/cdc-activities-for-improving-implementation-of-human-papillomavirus-vaccination-cervical-cancer-screening-and-surveillance-worldwide
#13
Virginia Senkomago, Denise Duran, Anagha Loharikar, Terri B Hyde, Lauri E Markowitz, Elizabeth R Unger, Mona Saraiya
Cervical cancer incidence and mortality rates are high, particularly in developing countries. Most cervical cancers can be prevented by human papillomavirus (HPV) vaccination, screening, and timely treatment. The US Centers for Disease Control and Prevention (CDC) provides global technical assistance for implementation and evaluation of HPV vaccination pilot projects and programs and laboratory-related HPV activities to assess HPV vaccines. CDC collaborates with global partners to develop global cervical cancer screening recommendations and manuals, implement screening, create standardized evaluation tools, and provide expertise to monitor outcomes...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29155655/synergies-between-communicable-and-noncommunicable-disease-programs-to-enhance-global-health-security
#14
Deliana Kostova, Muhammad J Husain, David Sugerman, Yuling Hong, Mona Saraiya, Jennifer Keltz, Samira Asma
Noncommunicable diseases are the leading cause of death and disability worldwide. Initiatives that advance the prevention and control of noncommunicable diseases support the goals of global health security in several ways. First, in addressing health needs that typically require long-term care, these programs can strengthen health delivery and health monitoring systems, which can serve as necessary platforms for emergency preparedness in low-resource environments. Second, by improving population health, the programs might help to reduce susceptibility to infectious outbreaks...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29155279/scalar-timing-in-memory-a-temporal-map-in-the-hippocampus
#15
Sorinel A Oprisan, Tristan Aft, Mona Buhus, Catalin V Buhusi
Decision making, rate calculation, and planning are examples of daily tasks we perform. They require accurate timing and involve many cortical areas such as the prefrontal cortex, the striatum, and the hippocampus. Although the neurobiological origin and the mechanisms of interval timing are largely unknown, we developed increasingly accurate mathematical and computational models that can mimic some properties of time perception. The accepted paradigm of temporal durations storage is that the objective elapsed time from the short-term memory is transferred to the reference memory using a multiplicative "memory translation constant" K*...
November 16, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29155188/a-case-of-spontaneous-bilateral-renal-artery-dissection-following-robotic-surgery
#16
James W H Macneil, Mona Razavian, Michael S Stephen, Howard M Lau
No abstract text is available yet for this article.
November 16, 2017: Urology
https://www.readbyqxmd.com/read/29154179/the-effect-of-follicullar-fluid-pesticides-and-polychlorinated-biphenyls-concentrations-on-intracytoplasmic-sperm-injection-icsi-embryological-and-clinical-outcome
#17
Tarek K Al-Hussaini, Ahmed A Abdelaleem, Ihab Elnashar, Omar M Shabaan, Rashad Mostafa, Mona A H El-Baz, Sahar E M El-Deek, Tarek A Farghaly
OBJECTIVES: The present study evaluated the correlation between the concentrations of polychlorinated biphenyls (PCBs) and pesticides in the follicular fluid (FF) obtained during intracytoplasmic sperm injection (ICSI) with the ovarian response, endometrial thickness, and embryological and clinical outcomes. DESIGN: Cross-sectional observational study. MATERIALS AND METHODS: Women aged 20 to 38 years (300 infertile couples) presenting to a university-affiliated fertility center were approached to participate in the study...
November 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29153888/-the-2015-classification-of-lung-adenocarcinomas-reproducibility-in-a-tunisian-department-specialised-in-thoracic-pathology
#18
Mona Mlika, Imen Helal, Emna Braham, Aida Ayadi, Ali Mrabet, Faouzi Mezni
INTRODUCTION: The new classification of lung cancer contains modifications of terminology and a new subdivision of the tumors with the most relevant modifications concerning the group of adenocarcinomas. The latter has been increasing and represents nowadays the most frequent type. Our aim was to assess the reproducibility of the new classification through the experience of a Department of Pathology specialized in thoracic pathology. METHODS: Our study included initially 106 cases diagnosed as adenocarcinomas and reviewed by 2 pathologists and 1 referee...
November 16, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/29152319/the-effect-of-sodium-bicarbonate-and-validation-of-beckman-coulter-au680-analyzers-for-measuring-total-carbon-dioxide-tco2-concentrations-in-horse-serum
#19
Levent Dirikolu, Pamela Waller, Mona Landry Waguespack, Frank Michael Andrews, Michael Layne Keowen, Stephen David Gaunt
This study evaluated the usage of Beckman Coulter AU680 analyzers for measurement of TCO 2 in horse serum, and the effect of sodium bicarbonate administrations on serum TCO 2 levels in resting horses. Treatment of horses with sodium bicarbonate did not result in any adverse events. Mean TCO 2 concentration was significantly higher from 1 to 8 h in the sodium bicarbonate-treated horses compared to the untreated controls. Within an hour, administration of sodium bicarbonate increased the TCO 2 level from 31...
November 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/29151981/cellular-uptake-of-plain-and-spion-modified-microbubbles-for-potential-use-in-molecular-imaging
#20
Mona Ahmed, Barbara Cerroni, Anton Razuvaev, Johan Härmark, Gaio Paradossi, Kenneth Caidahl, Björn Gustafsson
Introduction: Both diagnostic ultrasound (US) and magnetic resonance imaging (MRI) accuracy can be improved by using contrast enhancement. For US gas-filled microbubbles (MBs) or silica nanoparticles (SiNPs), and for MRI superparamagnetic or paramagnetic agents, contribute to this. However, interactions of MBs with the vascular wall and cells are not fully known for all contrast media. Methods: We studied the in vitro interactions between three types of non-targeted air-filled MBs with a polyvinyl-alcohol shell and murine macrophages or endothelial cells...
2017: Cellular and Molecular Bioengineering
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