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https://www.readbyqxmd.com/read/27911282/role-of-rehabilitation-in-hurler-s-syndrome
#1
Sudhir Ramkishore Mishra, Mona Shastri, Jaishree Ramesh
Hurler syndrome is an inherited autosomal recessive disorder of lysosomal accumulation of un-degraded glucosaminoglycan secondary to deficiency of a-L-Iduronidase enzyme. It is most severe form of Mucopolysaccharidosis with incidence of 1:100 000. It has multisystemic involvement leading to multiple deformity, disability and death within 10th years of life. A 2 year old boy presented with umbilical hernia, gross developmental delay and a progressive spinal deformity. On detailed clinical, radiological and laboratory investigation he was diagnosed as Hurler's syndrome...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27910417/new-numerical-simulation-method-to-calibrate-the-regular-hexagonal-nai-tl-detector-with-radioactive-point-sources-situated-non-axial
#2
Ayman Hamzawy, Dimitar N Grozdanov, Mohamed S Badawi, Fuad A Aliyev, Abouzeid A Thabet, Mahmoud I Abbas, Ivan N Ruskov, Ahmed M El-Khatib, Yuri N Kopatch, Mona M Gouda
Scintillation crystals are usually used for detection of energetic photons at room temperature in high energy and nuclear physics research, non-destructive analysis of materials testing, safeguards, nuclear treaty verification, geological exploration, and medical imaging. Therefore, new designs and construction of radioactive beam facilities are coming on-line with these science brunches. A good number of researchers are investigating the efficiency of the γ-ray detectors to improve the models and techniques used in order to deal with the most pressing problems in physics research today...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27908841/study-of-gene-polymorphisms-of-glutathione-s-transferase-t1-m1-in-egyptian-children-and-adolescents-with-type-1-diabetes-mellitus
#3
Naglaa Barseem, Mona Elsamalehy
OBJECTIVE: To evaluate the association of glutathione S- transferase mu 1 (GST M1) and glutathione S- transferase theta 1 (GST T1) polymorphisms with the development of T1DM and disease-related risk factors. METHODS: Sixty-four diabetic children and 41 controls were enrolled and subjected to fasting glucose, serum creatinine, lipid profile, HbA1c and evaluation of GST T1 and M1 genetic polymorphisms using polymerase chain reaction (PCR). RESULTS: There were significantly higher fasting glucose, glycosylated hemoglobin (HbA1c) and cholesterol in the diabetics...
December 2, 2016: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/27908396/the-fda-in-the-21st-century-how-is-the-fda-responding-to-the-new-world-a-focus-on-heart-failure-devices
#4
EDITORIAL
Matthew Hillebrenner, Bram Zuckerman, Mona Fiuzat, Norman Stockbridge, Robert Califf
No abstract text is available yet for this article.
December 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/27906805/predictors-of-positive-margins-at-time-of-loop-electrosurgical-excision-procedure
#5
Jill Liss, Meredith Alston, Mona B Krull, Sara E Mazzoni
OBJECTIVE: The aim of the study was to identify factors associated with the presence of high-grade squamous intraepithelial lesion (HSIL) at surgical margins of loop electrosurgical excision procedure (LEEP) pathology specimens. MATERIALS AND METHODS: All women evaluated for lower genital tract disease at a single academic institution were prospectively entered into a database. The database was queried for all women who had a LEEP performed for indications within contemporary American Society of Colposcopy and Cervical Pathology guidelines between April 1, 2013, and April 30, 2015...
November 30, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27905684/the-effect-of-maternal-and-infant-factors-on-cord-blood-yield
#6
REVIEW
Seyed Hadi Mousavi, Saeid Abroun, Morteza Zarrabi, Mona Ahmadipanah
Umbilical cord blood (CB) can be used as an alternative hematopoietic stem cell source for transplantation in hematological malignancy and blood disorders. The success of transplantation is highly related to the levels of total nucleated cell and CD34(+) cell counts. The evaluation of optimal conditions can decrease the rate of graft rejection due to low cell count and increases the quality of CB units (CBUs) in the blood bank and the success rate of engraftment. To this end, we review the maternal and infant parameters affecting the quality and quantity of CBUs...
December 1, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27904544/comparative-evaluation-of-conventional-and-bactec-methods-for-detection-of-bacterial-infection
#7
Afshin Mohammad Alizadeh, Rehyhaneh Kabiri Movahed, Mona Mohammadnia
BACKGROUND: Infectious diseases are a leading cause of morbidity and mortality in developing countries. The aim of this study was to compare the results of blood culture employing the conventional and BACTEC methods for detection of bacterial infection in Taleghani Hospital, Tehran. MATERIALS AND METHODS: This was a descriptive study carried out for 3 months (March 2014-May 2014) on 272 inpatients. Their blood culture results were analyzed using the two methods (BACTEC and conventional)...
2016: Tanaffos
https://www.readbyqxmd.com/read/27904529/anti-aggregatory-effect-of-boswellic-acid-in-high-fat-fed-rats-involvement-of-redox-and-inflammatory-cascades
#8
Mona Kamal Tawfik
INTRODUCTION: A high-fat diet is one of the main dietary factors promoting platelet aggregation. The present study was conducted to elucidate the involvement of boswellic acid (BA) on the platelet hyperaggregability in HFD-fed rats. As platelet hyperaggregability in HFD rats is closely linked to inflammation and enhanced free radical production, the present study was extended to evaluate the anti-inflammatory and anti-oxidative effect of BA on HFD-promoted platelet aggregation. MATERIAL AND METHODS: Rats were assigned to normal, HFD-fed, aspirin-treated (30 mg/kg), and BA-treated (250 and 500 mg/kg) groups...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27903055/local-landscape-effects-on-population-dynamics-of-ixodes-ricinus
#9
Naveed Asghar, Mona Petersson, Magnus Johansson, Patrik Dinnetz
Ixodes ricinus, a common tick in Europe, transmits severe tickborne pathogens (TBPs). In Sweden, both prevalence and incidence of tick-borne infections have increased during the last few decades, and a majority of the cases is reported from the area around Stockholm. Among ticks, transmission of TBPs involves co-feeding of susceptible larvae or nymphs with infected ticks on the same host. Seasonal synchrony of immature stages and total tick abundance are important factors for the probability of horizontal transmission of TBPs...
November 21, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27901344/effect-of-electromagnetic-waves-from-mobile-phone-on-immune-status-of-male-rats-possible-protective-role-of-vitamin-d
#10
Ola Ahmed El-Gohary, Mona Abdel-Azeem Said
There are considerable public concerns about the relationship between mobile phone radiation and human health. The present study assesses the effect of electromagnetic field (EMF) emitted from a mobile phone on the immune system in rats and the possible protective role of vitamin D. Rats were randomly divided into six groups: Group I: control group; Group II: received vitamin D (1000 IU/kg/day) orally; Group III: exposed to EMF 1 h/day; Group IV: exposed to EMF 2 h/day; Group V: exposed to EMF 1 h/day and received vitamin D (1000 IU/kg/day); Group VI: exposed to EMF 2 h/day and received vitamin D (1000 IU/kg/day)...
September 5, 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/27901291/success-rate-of-pneumatic-reduction-of-intussusception-with-and-without-sedation
#11
Oren Feldman, Giora Weiser, Mona Hanna, Ori Devir, Uri Balla, David W Johnson, Eran Kozer, Itai Shavit
BACKGROUND: Pneumatic reduction of ileocolic intussusception is often performed without sedation. The aim of this study was to evaluate the success rate of pneumatic reduction of intussusception with and without sedation. METHODS: We conducted a retrospective cohort study in Israel in two tertiary care centers using a similar protocol for pneumatic reduction of intussusception. In one center, patients had pneumatic reduction of intussusception under propofol-based sedation, while in the other, patients had pneumatic reduction of intussusception without any sedation...
November 30, 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27900602/transepithelial-transport-of-curcumin-in-caco-2-cells-is-significantly-enhanced-by-micellar-solubilisation
#12
Jan Frank, Christina Schiborr, Alexa Kocher, Jürgen Meins, Dariush Behnam, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab
Curcumin, the active constituent of Curcuma longa L. (family Zingiberaceae), has gained increasing interest because of its anti-cancer, anti-inflammatory, anti-diabetic, and anti-rheumatic properties associated with good tolerability and safety up to very high doses of 12 g. Nanoscaled micellar formulations on the base of Tween 80 represent a promising strategy to overcome its low oral bioavailability. We therefore aimed to investigate the uptake and transepithelial transport of native curcumin (CUR) vs. a nanoscaled micellar formulation (Sol-CUR) in a Caco-2 cell model...
November 29, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27898663/as-simple-as-possible-but-not-simpler-exploring-the-fidelity-of-coarse-grained-protein-models-for-simulated-force-spectroscopy
#13
Mona Habibi, Jörg Rottler, Steven S Plotkin
Mechanical unfolding of a single domain of loop-truncated superoxide dismutase protein has been simulated via force spectroscopy techniques with both all-atom (AA) models and several coarse-grained models having different levels of resolution: A Gō model containing all heavy atoms in the protein (HA-Gō), the associative memory, water mediated, structure and energy model (AWSEM) which has 3 interaction sites per amino acid, and a Gō model containing only one interaction site per amino acid at the Cα position (Cα-Gō)...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27896882/quality-of-claims-and-references-found-in-australian-pharmacy-journal-advertisements
#14
Mona Mandoh, Colin Michael Curtain
OBJECTIVES: To evaluate the quality of pharmaceutical advertisement claims and supporting references in Australian pharmacy journals that target community pharmacists. METHODS: All full-page advertisements for a medicinal product, found in two Australian pharmacy journals from the year 2012 to 2015 were included. Advertisement claims and references were evaluated by claim type (unambiguous to immeasurable) and level of evidence (strong to irrelevant) in supporting references...
November 29, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27895958/factors-associated-with-the-timeliness-of-electronic-nursing-documentation
#15
Meejung Ahn, Mona Choi, YoungAh Kim
OBJECTIVES: To investigate the factors associated with the timeliness of electronic nursing documentation using the entry time on the Electronic Medical Record (EMR) system. METHODS: As a retrospective study, data were extracted from January 1 to February 28, 2014 from a hospital EMR system and a nurses' personnel information system. The timeliness of instances of nursing documentation was categorized into 'timely' or 'untimely' according to whether the entry time was time-stamped within the working hours during each day, evening, or night shift...
October 2016: Healthcare Informatics Research
https://www.readbyqxmd.com/read/27895852/protein-protein-interaction-network-of-celiac-disease
#16
Mona Zamanian Azodi, Hassan Peyvandi, Mohammad Rostami-Nejad, Akram Safaei, Kamran Rostami, Reza Vafaee, Mohammadhossein Heidari, Mostafa Hosseini, Mohammad Reza Zali
AIM: The aim of this study is to investigate the Protein-Protein Interaction Network of Celiac Disease. BACKGROUND: Celiac disease (CD) is an autoimmune disease with susceptibility of individuals to gluten of wheat, rye and barley. Understanding the molecular mechanisms and involved pathway may lead to the development of drug target discovery. The protein interaction network is one of the supportive fields to discover the pathogenesis biomarkers for celiac disease...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27895461/sildenafil-potentiates-the-antitumor-activity-of-cisplatin-by-induction-of-apoptosis-and-inhibition-of-proliferation-and-angiogenesis
#17
Mona Mohamed El-Naa, Mohamed Othman, Sheren Younes
Sildenafil is the first phosphodiesterase-5 inhibitor used for the treatment of erectile dysfunction. However, recent studies have been suggesting an antitumor effect of sildenafil. The current study assessed the aforementioned activity of sildenafil in vivo and in vitro in solid-tumor-bearing mice and in a human cell line MCF-7, respectively. Moreover, we investigated the impact of sildenafil on cisplatin antitumor activity. The solid tumor was induced by inoculation of Ehrlich ascites carcinoma cells in female mice...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27895004/predictors-of-vascular-cognitive-impairment-poststroke-in-a-middle-eastern-bahrain-cohort-a-proposed-case-control-comparison
#18
Claire Donnellan, Mona Al Banna, Noor Redha, Adel Al Jishi, Isa Al Sharoqi, Safa Taha, Moiz Bakhiet, Fatema Abdulla, Patrick Walsh
BACKGROUND: Poststroke dementia and cognitive impairment are associated with poor long-term outcomes after stroke. The contribution of genetic factors such as the presence of apolipoprotein (ApoE) ɛ4 allele and its association with cognitive impairment poststroke remains inconclusive, particularly in Middle Eastern regions. OBJECTIVE: The aim of this study is to examine all correlates and potential predictors of cognitive impairment including self-awareness and regulation deficits in stroke patients and compare these functions with healthy older adults from a Middle Eastern population...
November 28, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27892641/the-effect-of-illustration-on-improving-text-comprehension-in-dyslexic-adults
#19
Mona Holmqvist Olander, Eva Wennås Brante, Marcus Nyström
This study analyses the effect of pictures in reading materials on the viewing patterns of dyslexic adults. By analysing viewing patterns using eye-tracking, we captured differences in eye movements between young adults with dyslexia and controls based on the influence of reading skill as a continuous variable of the total sample. Both types of participants were assigned randomly to view either text-only or a text + picture stimuli. The results show that the controls made an early global overview of the material and (when a picture was present) rapid transitions between text and picture...
November 28, 2016: Dyslexia: the Journal of the British Dyslexia Association
https://www.readbyqxmd.com/read/27891325/effect-of-tocopheryl-acetate-on-maternal-cigarette-smoke-exposed-swiss-albino-mice-inbred-fetus
#20
Janardan Chaudhary, Royana Singh, S N Shamal, K Supriya, Mona Srivastava, R S More
INTRODUCTION: Cigarette smoking is worldwide problem which can be correlated with teratogenicity. Tocopheryl acetate plays as an antioxidant against the oxidative stress evolved by cigarette smoke exposure during pregnancy. AIM: To study the effect of maternal exposure to cigarette smoke and Tocopheryl acetate on fetuses of mice. MATERIALS AND METHODS: Pregnant mice randomly assigned to different groups (Group I (control), Group II (Tocopheryl acetate), Group III(soyabean oil used as vehicle for Tocopheryl acetate), Group IV (Cigarette smoke Exposed), Group V (Cigarette smoke exposed plus Tocopheryl acetate) and Group VI(Cigarette smoke exposed plus soyabean oil) were exposed to cigarette smoke 3 times a day for 20 minutes each time and Tocopheryl acetate with dose of 200mg/kg/day in 0...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
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