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https://www.readbyqxmd.com/read/28097680/development-of-a-novel-algorithm-for-detecting-glucocorticoid-induced-diabetes-mellitus-using-a-medical-information-database
#1
T Imatoh, K Sai, K Hori, K Segawa, J Kawakami, M Kimura, Y Saito
WHAT IS KNOWN AND OBJECTIVE: Glucocorticoid-induced diabetes mellitus (GIDM) increases the risk of diabetes mellitus (DM)-related complications but is generally difficult to detect in clinical settings. The criteria for diagnosing GIDM have not been established. Recently, medical information databases (MIDs) have been used in post-marketing surveillance (PMS) studies. We conducted a pharmacoepidemiological study to develop an algorithm for detecting GIDM using MID. METHODS: We selected 1214 inpatients who were newly prescribed with a typical glucocorticoid, prednisolone, during hospitalization from 2008 to 2014 from an MID of Hamamatsu University Hospital in Japan...
January 18, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28094051/competition-policy-for-health-care-provision-in-portugal
#2
Pedro Pita Barros
We review the role of competition among healthcare providers in Portugal, which has a public National Health Service (NHS) at the core of the health system. There is little competition among healthcare providers within the NHS. Competition among NHS primary care providers is hindered by excess demand (many residents in Portugal do not have a designated family doctor). Competition among NHS hospitals has been traditionally limited to cases of maximum guaranteed waiting time for surgery being exceeded. The Portuguese Competition Authority enforces competition law...
December 23, 2016: Health Policy
https://www.readbyqxmd.com/read/28090511/emerging-trends-in-social-media-and-plastic-surgery
#3
REVIEW
Daniel J Gould, Hyuma A Leland, Adelyn L Ho, Ketan M Patel
Social media has increasingly changed the landscape of medicine and surgery and is rapidly expanding its influence in most peoples' lives. The average person spends nearly 2 hours per day using social media, consuming information about everything from family updates to entertainment news to presidential elections. The concentration of consumers on social media platforms has resulted in direct medicine and medical products marketing to consumers. Similarly, social media is increasingly becoming a platform for interaction between physicians and potential patients...
December 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28063134/how-can-pricing-and-reimbursement-policies-improve-affordable-access-to-medicines-lessons-learned-from-european-countries
#4
REVIEW
Sabine Vogler, Valérie Paris, Alessandra Ferrario, Veronika J Wirtz, Kees de Joncheere, Peter Schneider, Hanne Bak Pedersen, Guillaume Dedet, Zaheer-Ud-Din Babar
This article discusses pharmaceutical pricing and reimbursement policies in European countries with regard to their ability to ensure affordable access to medicines. A frequently applied pricing policy is external price referencing. While it provides some benchmark for policy-makers and has been shown to be able to generate savings, it may also contribute to delay in product launch in countries where medicine prices are low. Value-based pricing has been proposed as a policy that promotes access while rewarding useful innovation; however, implementing it has proven quite challenging...
January 6, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28060547/the-safety-of-sacubitril-valsartan-for-the-treatment-of-chronic-heart-failure
#5
Jeffrey M Tyler, John R Teerlink
Sacubitril-valsartan is a combination drug that contains the neprilysin inhibitor sacubitril and angiotensin II receptor blocker valsartan. In 2015, the US Food and Drug Administration approved sacubitril-valsartan for treatment of heart failure patients with reduced ejection fraction and New York Heart Association class II-IV symptoms following a large, Phase III clinical trial (PARADIGM-HF) that demonstrated a 20% reduction in the combined primary end-point of death from cardiovascular cause or hospitalization for heart failure compared to enalapril...
January 6, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28059955/diagnosis-of-opportunistic-infections-hiv-co-infections-tuberculosis
#6
Lesley Scott, Pedro da Silva, Catharina C Boehme, Wendy Stevens, Chris Gilpin
PURPOSE OF REVIEW: Tuberculosis (TB) incidence has declined ∼1.5% annually since 2000, but continued to affect 10.4 million individuals in 2015, with 1/3 remaining undiagnosed or underreported. The diagnosis of TB among those co-infected with HIV is challenging as TB remains the leading cause of death in such individuals. Accurate and rapid diagnosis of active TB will avert mortality in both adults and children, reduce transmission, and assist in timeous decisions for antiretroviral therapy initiation...
January 5, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28050682/competition-and-quality-indicators-in-the-health-care-sector-empirical-evidence-from-the-dutch-hospital-sector
#7
R R Croes, Y J F M Krabbe-Alkemade, M C Mikkers
There is much debate about the effect of competition in healthcare and especially the effect of competition on the quality of healthcare, although empirical evidence on this subject is mixed. The Netherlands provides an interesting case in this debate. The Dutch system could be characterized as a system involving managed competition and mandatory healthcare insurance. Information about the quality of care provided by hospitals has been publicly available since 2008. In this paper, we evaluate the relationship between quality scores for three diagnosis groups and the market power indicators of hospitals...
January 3, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28043708/emerging-roles-of-sodium-glucose-cotransporter-2-inhibitors-in-cardiology
#8
REVIEW
Atsushi Tanaka, Koichi Node
The ultimate goal of treatment in people with diabetes mellitus is to prevent development of cardiovascular (CV) disease, resulting in prolongation of healthy life expectancy. Although impaired glycemic metabolism has a central role in its pathology, a number of studies have demonstrated that remedy for its imbalance cannot necessarily be accomplished as a therapeutic goal. A comprehensive medical approach against multi-factorial pathologies in diabetes, such as insulin resistance, obesity, hypertension, and dyslipidemia, in addition to diet and exercise therapy should be rather performed in the routine clinical setting...
December 30, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/28041779/hospitalizations-within-14days-of-vaccination-among-pediatric-recipients-of-the-live-attenuated-influenza-vaccine-united-states-2010-2012
#9
Alexander J Millman, Sue Reynolds, Jonathan Duffy, Jufu Chen, Paul Gargiullo, Alicia M Fry
BACKGROUND: Live attenuated influenza vaccine (LAIV) is safe in healthy children ⩾2years. The original clinical trials excluded individuals with underlying conditions; however, post-marketing data suggest LAIV may be safe for these populations. METHODS: We analyzed MarketScan Commercial Claims Databases from 2010 to 2012 to describe hospitalizations within 14days of vaccination among LAIV recipients. We evaluated LAIV recipients aged 2-18years and defined underlying conditions by presence of inpatient or outpatient ICD-9 code during the previous calendar year...
December 29, 2016: Vaccine
https://www.readbyqxmd.com/read/28035843/within-the-triangle-of-healthcare-legacies-comparing-the-performance-of-south-eastern-european-health-systems
#10
Mihajlo Michael Jakovljevic, Jelena Arsenijevic, Milena Pavlova, Nick Verhaeghe, Ulrich Laaser, Wim Groot
OBJECTIVE: Inter-regional comparison of health-reform outcomes in south-eastern Europe (SEE). METHODS: Macro-indicators were obtained from the WHO Health for All Database. Inter-regional comparison among post-Semashko, former Yugoslavia and prior-1989-free-market SEE economies was conducted. RESULTS: United Nations Development Program Human Development Index growth was strongest among prior-free-market SEE followed by former Yugoslavia and post-Semashko...
December 30, 2016: Journal of Medical Economics
https://www.readbyqxmd.com/read/28035436/six-year-activity-on-approval-of-compassionate-use-of-medicines-by-the-ethics-committee-of-the-university-hospital-of-bologna-italy-time-to-update-rules-and-recommendations
#11
Nicola Montanaro, Mauro Melis, Stefania Proni, Giacomo Chiabrando, Domenico Motola
PURPOSE: Compassionate use of forthcoming drugs has become an increasing pathway through which patients can take advantage of promising medicines. We aimed to analyse the main features of the requests of compassionate use submitted to the Independent Ethics Committee (IEC) of the University Hospital of Bologna in the period 2010-2015. METHODS: The present analysis concerns the requests of compassionate use received by the IEC in the period 2010-2015. For each requested drug, we paired the date of the first request to our IEC with the date(s) of (a) submission to EMA, (b) CHMP positive opinion, and (c) European marketing authorization (if issued)...
December 29, 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28007050/an-adverse-drug-event-manager-facilitates-spontaneous-reporting-of-adverse-drug-reactions
#12
Siri Vinther, Pia Klarskov, Hanne Borgeskov, Perle Darsø, Anette Kvindebjerg Christophersen, Bille Borck, Catrine Christensen, Melissa Voigt Hansen, Natalie Monica Løvland Halladin, Mikkel Bring Christensen, Kirstine Moll Harboe, Marie Lund, Espen Jimenez-Solem
INTRODUCTION: Spontaneous reporting of adverse drug reactions (ADRs) is used for continuous risk-benefit evaluation of marketed pharmaceutical products and for signal detection. The Adverse Drug Event Manager (ADEM) is a service offered to clinicians employed at hospitals in the Capital Region of Denmark. The ADEM assists healthcare professionals in reporting suspected ADRs to the Danish Health Authority. The aim of this retrospective observational study was to quantify and describe ADRs reported via the ADEM in 2014...
January 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28005565/comparing-the-financial-impact-of-several-hospitals-on-their-local-markets
#13
Timothy Rotarius, Aaron Liberman
Several studies that measured the financial impact of hospitals on their local markets are examined. Descriptive analyses were performed to ascertain if there are any identifying characteristics and emerging patterns in the data. After hospitals were categorized into small, medium, and large classifications based on the number of employees, various predictive insights were discovered. Smaller hospitals could be expected to contribute approximately 7.3% to the local economy, whereas medium-sized hospitals would likely contribute approximately 11...
December 21, 2016: Health Care Manager
https://www.readbyqxmd.com/read/28003942/clinical-usage-and-economic-effectiveness-of-a-recently-developed-epidermal-autograft-harvesting-system-in-13-chronic-wound-patients-in-a-university-based-wound-center
#14
Angela Hulsey, Paul Linneman, Jeff Litt
INTRODUCTION:  Chronic wounds are a significant healthcare problem in the United States. Their costs approach 25 billion dollars in the United States. Current wound-care treatments of local wound care, moist dressings, and source control, while necessary for wound healing, are frequently not enough to ensure complete wound closure. The current surgical technique of split-thickness skin grafting is an operative procedure, painful, time-consuming, and leaves significant donor site wounds...
November 14, 2016: Curēus
https://www.readbyqxmd.com/read/27999486/identifying-eleven-factors-of-service-marketing-mix-4ps-effective-on-tendency-of-patients-toward-private-hospital
#15
Seyed Mojtaba Hosseini, Samira Etesaminia, Mehrnoosh Jafari
INTRODUCTION: One of the important factors of correct management is to identify the reasons for patient tendency toward private hospitals. This study measures these factors based on service marketing mixes. PATIENTS AND METHODS: This study used a cross sectional descriptive methodology. The study was conducted during 6 months in 2015. The studied population included patients of private hospitals in Tehran. Random sampling was used (n = 200). Data was collected by an author-made questionnaire for service marketing factors...
October 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/27998332/-electroshock-therapy-in-the-third-reich
#16
Lara Rzesnitzek, Sascha Lang
The history of 'electroshock therapy' (now known as electroconvulsive therapy (ECT)) in Europe in the Third Reich is still a neglected chapter in medical history. Since Thomas Szasz's 'From the Slaughterhouse to the Madhouse', prejudices have hindered a thorough historical analysis of the introduction and early application of electroshock therapy during the period of National Socialism and the Second World War. Contrary to the assumption of a 'dialectics of healing and killing', the introduction of electroshock therapy in the German Reich and occupied territories was neither especially swift nor radical...
January 2017: Medical History
https://www.readbyqxmd.com/read/27993434/competition-policy-for-health-care-provision-in-france
#17
Philippe Choné
There are more than two thousand hospitals in France, about equally divided between government-owned and privately-owned hospitals. Activity-based payment, which has been generalized in 2008 for acute care hospitals, has raised competition issues as DRG tariffs differ according to ownership status. Furthermore, the payment rule has been criticized for preventing the realization of potential hospital synergies, and as a result a recent reform has mandated close cooperation between public hospitals. The physician market is dual, with most GPs being subject to fee regulation and many self-employed, private-practice, specialist doctors being allowed to set their prices freely...
November 24, 2016: Health Policy
https://www.readbyqxmd.com/read/27984406/correlates-of-interorganizational-relationship-strategies-among-critical-access-hospitals
#18
Larry R Hearld, Nathaniel W Carroll, Kristine R Hearld, William Opoku-Agyeman
BACKGROUND: Interorganizational relationships (IORs) between hospitals and other health care providers have many potential benefits for critical access hospitals (CAHs) that operate in resource-constrained environments. Given the potential benefits of IORs, especially for CAHs, it is important to identify the conditions that support or hinder IOR development. However, most research examining IORs isolates individual types of relationships while ignoring the practical reality that many hospitals participate in a portfolio of relationships simultaneously...
December 15, 2016: Health Care Management Review
https://www.readbyqxmd.com/read/27981563/comparison-of-outcomes-following-a-switch-from-a-brand-to-an-authorized-vs-independent-generic-drug
#19
Richard A Hansen, Jingjing Qian, Richard L Berg, James G Linneman, Enrique Seoane-Vazquez, Sarah Dutcher, Saeid Raofi, C David Page, Peggy L Peissig
Authorized generics are identical in formulation to brand drugs, manufactured by the brand company but marketed as a generic. Generics, marketed by generic manufacturers, are required to demonstrate pharmaceutical and bioequivalence to the brand drug, but repetition of clinical trials is not required. This retrospective cohort study compared outcomes for generics and authorized generics, which serves as a generic vs. brand proxy that minimizes bias against generics. For the seven drugs studied between 1999-2014, 5,234 unique patients were on brand drug prior to generic entry and 4,900 (93...
December 16, 2016: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27974913/product-policy-the-main-component-of-the-marketing-mix-in-the-romanian-health-services
#20
EDITORIAL
B I Coculescu, V L Purcarea, E C Coculescu
The objectives of the reforms in the EU healthcare systems are based on the implementation of the marketing concept in the health systems, which are, among other things: • efficient management of the financial resources and control costs of the rendered health services; • increased satisfaction of the clients of health care services; • broad accessibility to health services; • effective implementation of modern technologies; • rational stimulation of medical services consumption; • achievement of a fair and neutral competition between the public/ private providers and health insurance companies; • introduction of performance criteria in order to increase the incomes of the medical staff and hierarchy in hospitals; • implementation of modern management methods in health services management; • decentralization of the public healthcare system...
January 2016: Journal of Medicine and Life
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