E L Nurmi, C P Laughlin, H de Wit, A A Palmer, J MacKillop, T D Cannon, R M Bilder, E Congdon, F W Sabb, L C Seaman, J J McElroy, M R Libowitz, J Weafer, J Gray, A C Dean, G S Hellemann, E D London
Risky decision-making is a common, heritable endophenotype seen across many psychiatric disorders. Its underlying genetic architecture is incompletely explored. We examined behavior in the Balloon Analogue Risk Task (BART), which tests risky decision-making, in two independent samples of European ancestry. One sample (n = 1138) comprised healthy participants and some psychiatric patients (53 schizophrenia, 42 bipolar disorder, 47 ADHD); the other (n = 911) excluded for recent treatment of various psychiatric disorders but not ADHD...
August 15, 2023: Molecular Psychiatry