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https://www.readbyqxmd.com/read/28550814/determination-of-equilibrium-structures-of-bromothymol-blue-revealed-by-using-quantum-chemistry-with-an-aid-of-multivariate-analysis-of-electronic-absorption-spectra
#1
Toru Shimada, Takeshi Hasegawa
The pH dependent chemical structures of bromothymol blue (BTB), which have long been under controversy, are determined by employing a combined technique of multivariate analysis of electronic absorption spectra and quantum chemistry. Principle component analysis (PCA) of the pH dependent spectra apparently reveals that only two chemical species are adequate to fully account for the color changes, with which the spectral decomposition is readily performed by using augmented alternative least-squares (ALS) regression analysis...
May 19, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28550022/longitudinal-assessment-of-brain-derived-neurotrophic-factor-in-sardinian-psychotic-patients-labsp-a-protocol-for-a-prospective-observational-study
#2
Diego Primavera, Mirko Manchia, Luca Deriu, Massimo Tusconi, Roberto Collu, Maria Scherma, Paola Fadda, Walter Fratta, Bernardo Carpiniello
INTRODUCTION: Brain-derived neurotrophic factor (BDNF) plays a crucial role in neurodevelopment, synaptic plasticity and neuronal function and survival. Serum and plasma BDNF levels are moderately, but consistently, decreased in patients with schizophrenia (SCZ) compared with healthy controls. There is a lack of knowledge, however, on the temporal manifestation of this decline. Clinical, illness course and treatment factors might influence the variation of BDNF serum levels in patients with psychosis...
May 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28549914/timing-of-permanent-ventricular-shunt-placement-following-external-ventricular-drain-placement-in-primary-intracerebral-hemorrhage
#3
Steven Ray Peters, David Tirschwell
BACKGROUND: Intraventricular hemorrhage requiring ventriculostomy placement is a frequent complication of spontaneous intracerebral hemorrhage. Although a subset of patients will require permanent ventricular shunt placement, little is known about contemporary practices regarding the timing of ventriculostomy and ventricular shunt placement after intracerebral hemorrhage. METHODS: Using the 2010-2012 National Inpatient Sample, we identified patients with International Classification of Diseases, Ninth Revision codes for intracerebral hemorrhage, excluded secondary causes, and examined procedure dates...
May 23, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28549612/variation-in-cesarean-birth-rates-by-labor-and-delivery-nurses
#4
Joyce K Edmonds, Michele O'Hara, Sean P Clarke, Neel Shah
OBJECTIVE: To examine variation in the cesarean birth rates of women cared for by labor and delivery nurses. DESIGN: Retrospective cohort study. SETTING: One high-volume labor and delivery unit at an academic medical center in a major metropolitan area. PARTICIPANTS: Labor and delivery nurses who cared for nulliparous women who gave birth to term, singleton fetuses in vertex presentation. METHODS: Data were extracted from electronic hospital birth records from January 1, 2013 through June 30, 2015...
May 23, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28549445/fibrinogen-early-in-severe-trauma-study-feisty-study-protocol-for-a-randomised-controlled-trial
#5
James Winearls, Martin Wullschleger, Elizabeth Wake, Catherine Hurn, Jeremy Furyk, Glenn Ryan, Melita Trout, James Walsham, Anthony Holley, Jeremy Cohen, Megan Shuttleworth, Wayne Dyer, Gerben Keijzers, John F Fraser, Jeffrey Presneill, Don Campbell
BACKGROUND: Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen replacement is recommended by several international trauma guidelines using either fibrinogen concentrate (FC) or cryoprecipitate (Cryo). There is limited evidence to support one product over the other with widespread geographic and institutional variation in practice. This pilot trial is the first randomised controlled trial comparing FC to Cryo in traumatic haemorrhage...
May 26, 2017: Trials
https://www.readbyqxmd.com/read/28549336/evaluation-of-a-new-random-access-hbv-dna-molecular-assay-the-veris-hbv-assay
#6
Slim Fourati, Dominique Challine, Jean-Dominique Poveda, Syria Laperche, Sandrine Rallier, Jean-Michel Pawlotsky, Stéphane Chevaliez
BACKGROUND: Detection and quantification of HBV DNA are essential to diagnose chronic HBV infection, monitor the virological response to treatment and the possible selection of resistant viruses in order to tailor therapy. The VERIS/MDx System HBV Assay is a random-access system that quantifies HBV DNA in clinical samples using unique single sample and reagent access during the workflow process without the need to reload other tests and delivers results within 1.2h following sampling...
May 17, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28549285/environmental-response-to-long-term-mariculture-activities-in-the-weihai-coastal-area-china
#7
Hongmei Li, Xiaomin Li, Qiang Li, Ying Liu, Jide Song, Yongyu Zhang
The environmental impacts of rapid expansion of mariculture have garnered worldwide attention. China is currently one of the largest countries to engage in this practice. In this study, a representative mariculture zone, the Weihai coastal area in China, was explored to determine the temporal variations in regional nutrients, N/P ratio, dissolved oxygen (DO), pH, chlorophyll a (Chl-a), and cellular abundance of diatoms and dinoflagellates in response to the rapid growth in mariculture activities between 2006 and 2014...
May 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28548543/systematic-review-of-clinical-guidance-documents-for-autism-spectrum-disorder-diagnostic-assessment-in-select-regions
#8
Melanie Penner, Evdokia Anagnostou, Lana Y Andoni, Wendy J Ungar
Clinical guidance documents play an important role in ensuring access to high-quality autism spectrum disorder diagnostic assessment practices. The objective was to perform a systematic review of professional association and government clinical guidance documents for autism spectrum disorder diagnostic assessment, analyzing their quality and content. The government search was limited to English-speaking, single-payer, publicly funded health systems. A quality appraisal was conducted by two appraisers using the Appraisal of Guidelines Research and Evaluation, second edition tool...
May 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28548368/developing-minimum-clinical-standards-for-physiotherapy-in-south-african-icus-a-qualitative-study
#9
Heleen van Aswegen, Shane Patman, Natascha Plani, Susan Hanekom
RATIONALE, AIMS, AND OBJECTIVES: Physiotherapists are integral members of the intensive care unit (ICU) team. Clinicians working in ICU are dependent on their own experience when making decisions regarding individual patient management thus resulting in variation in clinical practice. No formalized clinical practice guidelines or standards exist for the educational profile or scope of practice requirements for ICU physiotherapy. This study explored perceptions of physiotherapists on minimum clinical standards that ICU physiotherapists should adhere to for delivering safe, effective physiotherapy services to critically ill patients...
May 26, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28548301/night-to-night-variability-of-obstructive-sleep-apnea
#10
Anna S Stöberl, Esther I Schwarz, Sarah R Haile, Christopher D Turnbull, Valentina A Rossi, John R Stradling, Malcolm Kohler
One night of a sleep study is the standard for diagnosis and exclusion of obstructive sleep apnea. Single testing requires high sensitivity of the test method and a stable disease of interest to warrant a low rate of false-negative tests. Obstructive sleep apnea is diagnosed and graded by conventional thresholds of apneas and hypopneas per hour of sleep, and treatment is usually initiated in the presence of symptoms. The aim of this study was to assess night-to-night variability of obstructive sleep apnea to reassess the current practice...
May 26, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28548234/catheter-ablation-of-atrial-flutter-a-survey-focusing-on-post-ablation-oral-anticoagulation-management-and-ecg-monitoring
#11
Philipp Attanasio, Tabea Budde, Philipp Lacour, Abdul Shokor Parwani, Burkert Pieske, Florian Blaschke, Wilhelm Haverkamp, Leif-Hendrik Boldt, Martin Huemer
BACKGROUND: A considerable amount of patients with typical atrial flutter develops atrial fibrillation after CTI ablation. No uniform recommendations are available to guide anticoagulation regimes or ECG monitoring strategies after this procedure. METHODS: We conducted a web-based survey in electrophysiology (EP) centers in Germany, Switzerland and Austria. Responses were received from 47 centers. The survey was designed to investigate variations in management of the following: Ablation strategy, oral anticoagulation (OAC) management and ECG monitoring after successful cavotricuspid isthmus (CTI) ablation...
May 26, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28548000/assessment-for-improving-the-performance-of-nicus-the-italian-experience
#12
Simone Fanelli, Antonello Zangrandi
This paper describes neonatal intensive care units (NICU) in Italy using a set of organizational variables identifying management profile. The correlations between variables, and how these are impacted by structural aspects of the department or hospital, are investigated. The research was conducted within the 5-year far-reaching and complex SONAR study run by the Italian Neonatal Network, which maps NICU, monitors outcomes of member centres, defines organizational models, and identifies best practices to improve care quality...
January 1, 2017: Health Services Management Research
https://www.readbyqxmd.com/read/28546858/quality-indicators-for-the-acute-and-long-term-management-of-anaphylaxis-a-systematic-review
#13
REVIEW
Sangeeta Dhami, Aadam Sheikh, Antonella Muraro, Graham Roberts, Susanne Halken, Monserat Fernandez Rivas, Margitta Worm, Aziz Sheikh
BACKGROUND: The quality of acute and long-term anaphylaxis management is variable and this contributes to the poor outcomes experienced by many patients. Clinical practice guidelines have the potential to improve outcomes, but implementing guideline recommendations in routine practice is challenging. Quality indicators have the potential to support guideline implementation efforts. OBJECTIVE: To identify quality indicators to support the acute and long-term management of anaphylaxis...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28546222/prevalence-of-celiac-disease-in-52-721-youth-with-type-1-diabetes-international-comparison-across-three-continents
#14
Maria E Craig, Nicole Prinz, Claire T Boyle, Fiona M Campbell, Timothy W Jones, Sabine E Hofer, Jill H Simmons, Naomi Holman, Elaine Tham, Elke Fröhlich-Reiterer, Stephanie DuBose, Helen Thornton, Bruce King, David M Maahs, Reinhard W Holl, Justin T Warner
OBJECTIVE: Celiac disease (CD) has a recognized association with type 1 diabetes. We examined international differences in CD prevalence and clinical characteristics of youth with coexisting type 1 diabetes and CD versus type 1 diabetes only. RESEARCH DESIGN AND METHODS: Data sources were as follows: the Prospective Diabetes Follow-up registry (Germany/Austria); the T1D Exchange Clinic Network (T1DX) (U.S.); the National Paediatric Diabetes Audit (U.K. [England/Wales]); and the Australasian Diabetes Data Network (ADDN) (Australia)...
May 25, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28545916/long-term-success-and-failure-with-sg-is-predictable-by-3-months-a-multivariate-model-using-simple-office-markers
#15
Austin Cottam, Josiah Billing, Daniel Cottam, Peter Billing, Samuel Cottam, Hinali Zaveri, Amit Surve
INTRODUCTION: Despite being the most common surgery in the United States, little is known about predicting weight loss success and failure with sleeve gastrectomy (SG). Papers that have been published are inconclusive. We decided to use multivariate analysis from 2 practices to design a model to predict weight loss outcomes using data widely available to any surgical practice at 3 months to determine weight loss outcomes at 1 year. SETTING: Two private practices in the United States...
March 23, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28545681/survey-of-uk-imaging-practice-for-the-investigation-of-pulmonary-embolism-in-pregnancy
#16
L Armstrong, F Gleeson, L Mackillop, S Mutch, A Beale
AIM: To determine the utilisation of computed tomography pulmonary angiography (CTPA) and lung scintigraphy in the UK, and to assess their diagnostic qualities in the investigation of suspected pulmonary embolism (PE) in pregnancy. MATERIALS AND METHODS: Data were collected via electronic questionnaire in the UK from 24 sites. Data on the choice of imaging technique, radiation dose, technical adequacy, weeks' gestation, presenting symptoms, and further management of patients with indeterminate imaging were collected...
May 22, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28545582/gender-differences-in-hypertension-awareness-antihypertensive-use-and-blood-pressure-control-in-bangladeshi-adults-findings-from-a-national-cross-sectional-survey
#17
Muntasirur Rahman, Gail Williams, Abdullah Al Mamun
BACKGROUND: Bangladesh is facing an epidemiological transition with a growing burden of non-communicable diseases. Traditionally, hypertension and associated complications in women receive less recognition, and there is a dearth of related publications. The study aims to explore gender differences in high blood pressure awareness and antihypertensive use in Bangladeshi adults at the community level. Another objective is to identify factors associated with uncontrolled hypertension among antihypertensive users...
May 25, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28545561/sources-of-variability-in-the-measurement-of-ascaris-lumbricoides-infection-intensity-by-kato-katz-and-qpcr
#18
Alice V Easton, Rita G Oliveira, Martin Walker, Elise M O'Connell, Sammy M Njenga, Charles S Mwandawiro, Joanne P Webster, Thomas B Nutman, Roy M Anderson
BACKGROUND: Understanding and quantifying the sources and implications of error in the measurement of helminth egg intensity using Kato-Katz (KK) and the newly emerging "gold standard" quantitative polymerase chain reaction (qPCR) technique is necessary for the appropriate design of epidemiological studies, including impact assessments for deworming programs. METHODS: Repeated measurements of Ascaris lumbricoides infection intensity were made from samples collected in western Kenya using the qPCR and KK techniques...
May 25, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28545545/a-focused-ethnography-of-a-child-and-adolescent-mental-health-service-factors-relevant-to-the-implementation-of-a-depression-trial
#19
C E W Kitchen, S Lewis, P A Tiffin, P R Welsh, L Howey, D Ekers
BACKGROUND: Prior to commencing a randomised controlled trial, we conducted a focused ethnography to ensure that the trial was well suited to the proposed setting. METHODS: A six-month observation of a Child and Adolescent Mental Health Service site in the North-East of England was undertaken to observe the site procedures, staff culture and patient care pathways. During this period, documentary data were collected and interviews were conducted with key informants to provide insight into staff perceptions of the proposed trial...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28545535/electronic-audit-and-feedback-intervention-with-action-implementation-toolbox-to-improve-pain-management-in-intensive-care-protocol-for-a-laboratory-experiment-and-cluster-randomised-trial
#20
Wouter T Gude, Marie-José Roos-Blom, Sabine N van der Veer, Evert de Jonge, Niels Peek, Dave A Dongelmans, Nicolette F de Keizer
BACKGROUND: Audit and feedback is often used as a strategy to improve quality of care, however, its effects are variable and often marginal. In order to learn how to design and deliver effective feedback, we need to understand their mechanisms of action. This theory-informed study will investigate how electronic audit and feedback affects improvement intentions (i.e. information-intention gap), and whether an action implementation toolbox with suggested actions and materials helps translating those intentions into action (i...
May 25, 2017: Implementation Science: IS
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