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https://www.readbyqxmd.com/read/29044563/the-impact-of-socioeconomic-status-on-stage-specific-prostate-cancer-survival-and-mortality-before-and-after-introduction-of-psa-test-in-finland
#1
Heikki A Seikkula, Antti J Kaipia, Heidi Ryynänen, Karri Seppä, Janne M Pitkäniemi, Nea K Malila, Peter J Boström
Socioeconomic status (SES) has an impact on prostate cancer (PCa) outcomes. Men with high SES have higher incidence and lower mortality of PCa versus lower SES males. PCa cases diagnosed in Finland in 1985-2014 (N=95076) were identified from the Finnish Cancer Registry. Information on education level (EL) was obtained from Statistics Finland. EL was assessed with three-tiered scale: basic, upper secondary and higher education. PCa stage at diagnosis was defined as localized, metastatic or unknown. Years of diagnosis 1985-1994 were defined as pre-PSA period and thereafter as post-PSA period...
October 16, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29043949/arthroscopic-surgery-for-knee-osteoarthritis-impact-of-health-technology-assessment-in-germany
#2
Naomi Fujita-Rohwerder, Alric Rüther, Stefan Sauerland
OBJECTIVES: This study aims to describe how a negative reimbursement decision-based on the health technology assessment (HTA) report of a nondrug intervention-affects healthcare providers in Germany. METHODS: Knee arthroscopy was chosen as an example, because as of April 2016 this procedure is no longer reimbursed for osteoarthritis, but is still covered for other indications, including meniscal lesions. The exclusion followed an HTA report prepared by the Institute for Quality and Efficiency in Health Care (IQWiG)...
October 18, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29043922/barriers-and-facilitators-to-dispensing-of-intranasal-naloxone-by-pharmacists
#3
Ludmila N Bakhireva, Adriana Bautista, Sandra Cano, Shikhar Shrestha, Amy M Bachyrycz, Theresa H Cruz
BACKGROUND: While misuse of prescription opioids has reached epidemic proportions, pharmacy-based preventive services to combat this epidemic are limited. The aims of this study were to identify barriers and facilitators to the dispensing of intranasal naloxone (INN) by pharmacists in New Mexico. METHODS: For this mixed methods study, a qualitative component (focus group) informed the development of a quantitative component (electronic survey) distributed to all pharmacists registered with the New Mexico Board of Pharmacy and practicing in the state...
October 18, 2017: Substance Abuse
https://www.readbyqxmd.com/read/29042408/impact-of-restricting-diagnostic-imaging-reimbursement-for-uncomplicated-low-back-pain-in-ontario-a-population-based-interrupted-time-series-analysis
#4
Benjamin Fine, Susan E Schultz, Lawrence White, David Henry
BACKGROUND: In 2012, the Ontario government withdrew public insurance coverage of imaging tests for uncomplicated low back pain. We studied the impact of this restriction on test ordering by physicians. METHODS: We compared the numbers of lumbar spine radiography, computed tomography (CT) and single-segment magnetic resonance imaging (MRI) studies ordered by physicians in the 3 years before and after the policy change. We linked claims data from the Ontario Health Insurance Program with physician details to calculate rates per test-ordering physician...
October 13, 2017: CMAJ Open
https://www.readbyqxmd.com/read/29042372/awareness-and-willingness-towards-pre-exposure-prophylaxis-against-hiv-infection-among-individuals-seeking-voluntary-counselling-and-testing-for-hiv-in-taiwan-a-cross-sectional-questionnaire-survey
#5
Yi-Chieh Lee, Sui-Yuan Chang, Kuan-Yin Lin, Lan-Hsin Chang, Wen-Chun Liu, Cheng-Hsin Wu, Hsin-Yun Sun, Chien-Ching Hung, Shan-Chwen Chang
OBJECTIVES: We aimed to investigate the awareness and willingness towards pre-exposure prophylaxis (PrEP) among individuals seeking voluntary counselling and testing (VCT) for HIV in Taiwan, where PrEP is currently not reimbursed by the insurance. METHODS: Between April and October 2016, a questionnaire interview was conducted among VCT clients to inquire about the attitudes towards PrEP against HIV infection. Multivariate logistic regression analysis was performed to identify the associated factors with willingness to initiate PrEP...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042060/australian-general-practitioners-initiate-statin-therapy-primarily-on-the-basis-of-lipid-levels-new-zealand-general-practitioners-use-absolute-risk
#6
REVIEW
Chris Schilling, Josh Knight, Duncan Mortimer, Dennis Petrie, Philip Clarke, John Chalmers, Andrew Kerr, Rod Jackson
OBJECTIVES: To compare the determinants of initial statin prescribing between New Zealand and Australia. New Zealand has a system-wide absolute risk-based approach to primary care cardiovascular disease (CVD) management, while Australia has multiple guidelines. METHOD: Classification and Regression Tree (CART) analysis of two observational studies of primary care CVD management from New Zealand (PREDICT-CVD) and Australia (AusHeart). Over 80% of eligible New Zealanders have been screened for CVD risk...
October 10, 2017: Health Policy
https://www.readbyqxmd.com/read/29041915/cost-effectiveness-analysis-of-xelox-versus-xelox-plus-bevacizumab-for-metastatic-colorectal-cancer-in-a-public-hospital-school
#7
Andrea Queiróz Ungari, Leonardo Régis Leira Pereira, Altacílio Aparecido Nunes, Fernanda Maris Peria
BACKGROUND: Metastatic colorectal cancer imposes a substantial burden on patients and society. Over the last years, progresses in the treatment have been made especially due to the introduction of monoclonal antibodies, such as bevacizumab which, on the other hand, has considerably increased the costs of treatment. We performed a cost-effectiveness analysis of bevacizumab plus XELOX in comparison with XELOX alone in metastatic colorectal cancer in first-line therapy, from the perspective of a public hospital school in Brazil...
October 17, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29039685/health-technology-assessment-process-of-a-cardiovascular-medical-device-in-four-different-settings
#8
Antonio Olry de Labry Lima, Jaime Espín Balbino, Alexandre Lemgruber, Araceli Caro Martínez, Leticia García-Mochón, Eva Martín Ruiz, Fernanda Lessa
AIM: Health technology assessment (HTA) is a tool to help the decision-making process. The aim is to describe methods and processes used in the reimbursement decision making for drug-eluting stents (DES) in four different settings. METHODS: DES as a technology under study was selected according to different criteria, all of them agreed by a working group. A survey of key informants was designed. RESULTS: DES was evaluated following well-structured HTA processes...
October 17, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29039627/beliefs-endorsement-and-application-of-homeopathy-disclosed-a-survey-among-ambulatory-care-physicians
#9
Stefan Markun, Marc Maeder, Thomas Rosemann, Sima Djalali
BACKGROUND: Explanation models for the effectiveness of homeopathy are not supported by natural sciences and the aggregated evidence from clinical trials is unconvincing. From this standpoint, placebo effects seem the most obvious explanation for the therapeutic effects experienced in homeopathy. Still, many physicians continue to prescribe homeopathic treatments. OBJECTIVES: Whether physicians who prescribe homeopathic treatments aim to achieve placebo effects or actually believe in specific effects is poorly understood...
October 17, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29039054/treatment-persistence-and-healthcare-costs-among-patients-with-rheumatoid-arthritis-changing-biologics-in-the-usa
#10
Benjamin Chastek, Chieh-I Chen, Clare Proudfoot, Shraddha Shinde, Andreas Kuznik, Wenhui Wei
INTRODUCTION: After a patient with rheumatoid arthritis (RA) fails tumor necrosis factor inhibitor (TNFi) treatment, clinical guidelines support either cycling to another TNFi or switching to a different mechanism of action (MOA), but payers often require TNFi cycling before they reimburse switching MOA. This study examined treatment persistence, cost, and cost per persistent patient among MOA switchers versus TNFi cyclers. METHODS: This study of Commercial and Medicare Advantage claims data from the Optum Research Database included patients with RA and at least one claim for a TNFi (adalimumab, certolizumab pegol, etanercept, golimumab, or infliximab) between January 2012 and September 2015 who changed to another TNFi or a different MOA therapy (abatacept, tocilizumab, or tofacitinib) within 1 year...
October 16, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29038733/mining-comorbidity-patterns-using-retrospective-analysis-of-big-collection-of-outpatient-records
#11
Svetla Boytcheva, Galia Angelova, Zhivko Angelov, Dimitar Tcharaktchiev
BACKGROUND: Studying comorbidities of disorders is important for detection and prevention. For discovering frequent patterns of diseases we can use retrospective analysis of population data, by filtering events with common properties and similar significance. Most frequent pattern mining methods do not consider contextual information about extracted patterns. Further data mining developments might enable more efficient applications in specific tasks like comorbidities identification. METHODS: We propose a cascade data mining approach for frequent pattern mining enriched with context information, including a new algorithm MIxCO for maximal frequent patterns mining...
December 2017: Health Information Science and Systems
https://www.readbyqxmd.com/read/29035903/the-future-of-obstetrics-and-gynecology-macra-electronic-health-records-and-more
#12
Deborah A Wing
There is immense change affecting obstetrical and gynecologic medical practice at this moment in time-involving reimbursement with the shift from volume-based to value-based care, increasing regulation, and workforce sustainability. Aspects to be reviewed in this chapter include reimbursements and Medicare Access and CHIP Reauthorization Act of 2015 (MACRA), electronic medical records, physician satisfaction surveys, maintenance of certification, and physician burnout.
December 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29033060/a-review-of-international-coverage-and-pricing-strategies-for-personalized-medicine-and-orphan-drugs
#13
REVIEW
Irina Degtiar
BACKGROUND: Personalized medicine and orphan drugs share many characteristics-both target small patient populations, have uncertainties regarding efficacy and safety at payer submission, and frequently have high prices. Given personalized medicine's rising importance, this review summarizes international coverage and pricing strategies for personalized medicine and orphan drugs as well as their impact on therapy development incentives, payer budgets, and therapy access and utilization...
September 29, 2017: Health Policy
https://www.readbyqxmd.com/read/29031682/-rates-of-total-and-free-psa-prescriptions-in-france-2012-2014
#14
Philippe Tuppin, Claire Leboucher, Gabrielle Peyre-Lanquar, Pierre-Jean Lamy, Pierre Gabach, Xavier Rébillard
BACKGROUND: In 2010, the French Haute Autorité de santé (National Health Authority) confirmed the limited value of prostate cancer (PCa) screening by total prostate-specific antigen (PSA) assay. OBJECTIVE: This study was designed to determine the modalities of ordering total PSA or free PSA assays (in the absence of PCa) according to various parameters and the corresponding sums reimbursed. METHODS: Men aged 40 years and older covered by the national health insurance general scheme (73% of the French population) between 2012 and 2014 were selected...
October 11, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29031290/privately-practising-nurse-practitioners-provision-of-care-subsidised-through-the-medicare-benefits-schedule-and-the-pharmaceutical-benefits-scheme-in-australia-results-from-a-national-survey
#15
Jane Currie, Mary Chiarella, Thomas Buckley
Objective Since legislative changes in 2010, certain health care services provided by privately practising nurse practitioners (PPNPs) in Australia have been eligible for reimbursement under the Medicare Benefits Schedule (MBS) and the Pharmaceutical Benefits Scheme (PBS). The aim of the present study was to describe survey results relating to the care provided by PPNPs subsidised through the MBS and PBS.Methods PPNPs in Australia were invited to complete an electronic survey exploring their practice activities...
October 16, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29031037/-evaluation-of-anti-cancer-therapies-with-reimbursement-limited-to-comprehensive-cancer-centres-using-the-european-society-for-medical-oncology-magnitude-of-clinical-benefit-scale
#16
T Büchler, B Melichar, D Vrána, R Lemstrová, J Fínek, L Dušek, K Petráková, J Prausová
BACKGROUND: The costs of oncology treatments are increasing, due to the rising prevalence of malignant diseases and the introduction of expensive novel anti-cancer agents. The new European Society for Clinical Oncology (ESMO) has recently developed a new parametric system to evaluate the clinical benefit of drugs. The Magnitude of Clinical Benefit Scale (ESMO-MCBS) compares the contribution of a novel drug based on overall and progression-free survival and quality of life with those of current treatment options...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/29029551/low-back-pain-investigation-of-biases-in-outpatient-canadian-physical-therapy
#17
Maude Laliberté, Barbara Mazer, Tatiana Orozco, Gevorg Chilingaryan, Bryn Williams-Jones, Matthew Hunt, Debbie Ehrmann Feldman
Background: Previous research suggested that physical therapy services can be influenced by patient characteristics (age, sex, socioeconomic status) or insurance status rather than their clinical need. Objective: The aim of this study was to determine whether patient-related factors (age, sex, SES) and the source of reimbursement for physical therapy services (insurance status) influence wait time for, frequency of, and duration of physical therapy for low back pain...
October 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29028119/comparison-of-treatment-persistence-with-dabigatran-or-rivaroxaban-versus-vitamin-k-antagonist-oral-anticoagulants-in-atrial-fibrillation-patients-a-competing-risk-analysis-in-the-french-nationwide-healthcare-databases
#18
Géric Maura, Cécile Billionnet, François Alla, Joshua J Gagne, Antoine Pariente
BACKGROUND: Direct oral anticoagulants (DOACs) have been proposed as a more convenient alternative to vitamin K antagonists (VKAs), which are commonly associated with poor treatment persistence in nonvalvular atrial fibrillation (nv-AF). METHODS: Using data from the French National Healthcare databases (Régime Général, 50 million beneficiaries), a cohort study was conducted to compare the 1-year non-persistence rates in nv-AF patients initiating dabigatran (N=11,141) or rivaroxaban (N=11,126) versus VKA (N=11,998)...
October 13, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/29026296/trends-in-health-care-resource-utilization-and-pharmacological-management-of-copd-in-taiwan-from-2004-to-2010
#19
Ying-Huang Tsai, Tsung-Ming Yang, Chieh-Mo Lin, Shu-Yi Huang, Yu-Wen Wen
RATIONALE: COPD has attracted widespread attention worldwide. The prevalence of COPD in Taiwan has been reported, but little is known about trends in health care resource utilization and pharmacologic management in COPD treatment. OBJECTIVE: The objective of this article was to study trends in health care resource utilization, pharmacologic management, and medical costs of COPD treatment in Taiwan. MATERIALS AND METHODS: Reimbursement claims in the Taiwan National Health Insurance System from 2004 to 2010 were collected...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29025143/cost-effectiveness-of-the-pharmacist-assisted-warfarin-monitoring-program-at-a-medical-center-in-taiwan
#20
Jen-Yu Chang, Chi-Chuan Wang, Hao-Cheng Kang, Li-Jiuan Shen, Chih-Fen Huang
Objective: To investigate the cost-effectiveness of the first patient self-paying pharmacist-assisted warfarin monitoring (PAWM) program in Taiwan. Design: A Markov model with a 1-month cycle length and a 20-year time horizon was employed in this study. The model is composed of the following eight states: three no-event states (i.e. 'subtherapeutic,' 'within therapeutic' and 'supratherapeutic' states), two serious adverse events (AEs) (i.e. bleeding and thromboembolism), two sequelae states and death...
August 22, 2017: International Journal for Quality in Health Care
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