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https://www.readbyqxmd.com/read/29777951/experimental-referred-pain-extends-towards-previously-injured-location-an-explorative-study
#1
Thorvaldur Skuli Palsson, Shellie A Boudreau, Hans Jørgen Krebs, Thomas Graven-Nielsen
Facilitated pain mechanisms have been demonstrated in musculoskeletal pain but it is unclear whether a recent painful injury leaves the pain system sensitized. Pain characteristics were assessed in individuals who recently recovered from ankle pain (recovered pain group; n=25) and sex-matched controls (n=25) in response to tonic-pressure pain and saline-induced pain applied at the shin muscle. Pain intensity and pain referral patterns were recorded bilaterally after the painful muscle stimulus. Pressure pain thresholds (PPTs) were measured at the lower legs and shoulder...
May 16, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29742000/haemoproteus-parahaemoproteus-spp-in-captive-bred-bobwhite-quail-colinus-virginianus-in-southern-utah-usa
#2
E Jane Kelly, Thomas J Baldwin, David D Frame, April L Childress, James F X Wellehan
A captive-bred Bobwhite Quail ( Colinus virginianus) ranch in southern Utah experienced high mortality rates in the late summer and fall of 2012. Nine juvenile birds were necropsied at the Utah Veterinary Diagnostic Laboratory. Gross lesions included pale skeletal muscle with multifocal hemorrhages and petechiae in the air sacs and serosal surfaces of most organs. Histologically there was moderate to severe, multifocal, degenerative myositis with intramyofiber schizonts and minimal lymphoplasmacytic infiltrates in the proventriculus, ventriculus, heart, and skeletal muscle...
May 9, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29732389/the-prognostic-role-of-the-change-in-neutrophil-to-lymphocyte-ratio-during-neoadjuvant-chemotherapy-in-patients-with-muscle-invasive-bladder-cancer-a-retrospective-multi-institutional-study
#3
Jeenan Kaiser, Haocheng Li, Scott A North, Raya Leibowitz-Amit, Jo-An Seah, Nisha Morshed, Caroline Chau, Richard Lee-Ying, Daniel Y C Heng, Srikala Sridhar, Simon J Crabb, Nimira S Alimohamed
Background: The impact of the change in the neutrophil-to-lymphocyte ratio (NLR) during neoadjuvant chemotherapy (NAC) on outcomes in patients with muscle-invasive bladder cancer (MIBC) is poorly understood. Objective: To evaluate the prognostic impact of the change in NLR during NAC for patients with MIBC. Methods: Patients referred to academic, community, and quaternary referral centres in Alberta, Canada from 2005 to 2015, Ontario, Canada from 2005 to 2013, and Southampton, UK from 2004 to 2010 were evaluated...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29710183/an-update-on-the-management-of-neonatal-brachial-plexus-palsy-replacing-old-paradigms-a-review
#4
Brandon W Smith, Alecia K Daunter, Lynda J-S Yang, Thomas J Wilson
Importance: Neonatal brachial plexus palsy (NBPP) can result in persistent deficits for those who develop it. Advances in surgical technique have resulted in the availability of safe, reliable options for treatment. Prevailing paradigms include, "all neonatal brachial plexus palsy recovers," "wait a year to see if recovery occurs," and "don't move the arm." Practicing by these principles places these patients at a disadvantage. Thus, the importance of this review is to provide an update on the management of NBPP to replace old beliefs with new paradigms...
April 30, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29705166/differences-in-knee-and-hip-adduction-and-hip-muscle-activation-in-runners-with-and-without-iliotibial-band-syndrome
#5
Robert L Baker, Richard B Souza, Mitchell J Rauh, Michael Fredericson, Michael D Rosenthal
BACKGROUND: Iliotibial Band Syndrome has been associated with altered hip and knee kinematics in runners. Prior studies have recommended further research on neuromuscular factors at the hip. The frontal plane hip muscles have been a strong focus in strength comparison, but not for electromyography investigation. OBJECTIVE: To compare hip surface electromyography, and frontal plane hip and knee kinematics, in runners with and without iliotibial band syndrome. DESIGN: Observational cross sectional study, 30 participants were tested for motion capture at the hip and knee and muscle activation in the lateral and posterior hip...
April 26, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29705078/therapist-s-practice-patterns-for-subsequent-fall-osteoporotic-fracture-prevention-for-patients-with-a-distal-radius-fracture
#6
Neha Dewan, Joy C MacDermid, Norma J MacIntyre, Ruby Grewal
STUDY DESIGN: Cross-sectional survey. INTRODUCTION: Multifactorial risk factor screening and treatment is needed for subsequent falls/osteoporotic fractures prevention (SFOFP), given the elevated risk among patients with distal radius fracture (DRF). PURPOSE OF THE STUDY: The primary objective was to describe hand therapists' knowledge and clinical practice patterns for assessment, treatment, referral, and education with respect to SFOFP for patients with DRF older than 45 years...
April 25, 2018: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29696046/clinical-features-and-outcome-of-guillain-barr%C3%A3-syndrome-in-children
#7
Jafar Nasiri, Mohamadreza Ghazavi, Omid Yaghini, Mohamad Chaldavi
Objective: There are no reports about the clinical presentations and outcome of Guillain-Barré syndrome (GBS) in our region, therefore, we aimed to report some mentioned findings in children diagnosed with GBS in Isfahan, central Iran. Materials & Methods: In this retrospective study, pediatric diagnosed with GBS referred to Imam Hossein Hospital, the Pediatric Referral Center of Isfahan Province, central Iran were enrolled from 2011-2014. The following data were extracted from the medical files of patients; age, gender, early signs and symptoms of GBS, neurological features, sensory and motor and autonomic involvements, sphincter dysfunction, bulbar muscle involvement, respiratory failure, cranial nerve paralysis, delay time from onset to definite diagnosis and management of GBS and the outcome...
2018: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29687940/performance-evaluation-and-validation-of-the-animal-trauma-triage-score-and-modified-glasgow-coma-scale-with-suggested-category-adjustment-in-dogs-a-vetcot-registry-study
#8
Kristian Ash, Galina M Hayes, Robert Goggs, Julia P Sumner
OBJECTIVE: To examine the animal trauma triage (ATT) and modified Glasgow Coma Scale (mGCS) scores as predictors of mortality outcome (death or euthanasia) in injured dogs. DESIGN: Observational cohort study conducted from September 2013 to March 2015 with follow-up until death or hospital discharge. SETTING: Nine veterinary hospitals including private referral and veterinary teaching hospitals. ANIMALS: Consecutive sample of 3,599 dogs with complete data entries recruited into the Veterinary Committee on Trauma patient registry...
April 24, 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29621862/temporomandibular-dysfunction
#9
Jonathan Lomas, Taylan Gurgenci, Christopher Jackson, Duncan Campbell
BACKGROUND: Orofacial pain is a common presentation in the primary healthcare setting and temporomandibular dysfunction represents one of the major causes. Its aetiology is multifactorial, caused by both masticatory muscle dysfunction and derangement within the temporomandibular joint. OBJECTIVE: The aim of this article is to provide an overview of temporomandibular dysfunction, its management and referral considerations for general practioners. DISCUSSION: Temporomandibular joint dysfunction affects a large number of adults...
April 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29620662/good-outcomes-after-the-delayed-removal-of-an-epidural-hematoma-a-case-report
#10
Yong-Xing Yao, Ming-Xia Li, Lian-Juan Sun
RATIONALE: Epidural hematomas can develop following intrathecal puncture, spinal vascular malformation, or spontaneous hemorrhage. Prompt recognition of symptoms and referral to neurosurgical services are crucial for recovery. We report a rare case of delayed removal of an epidural hematoma that resulted in good patient outcomes. PATIENT CONCERNS: A 69-year-old woman weighing 58 kg presented with back pain that had persisted for 12 years. Her medical history was notable for hypertension...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29608510/pressure-induced-referred-pain-areas-are-more-expansive-in-individuals-with-a-recovered-fracture
#11
Víctor Doménech-García, Thorvaldur Skuli Palsson, Shellie Ann Boudreau, Pablo Herrero, Thomas Graven-Nielsen
Musculoskeletal trauma and pain can sensitize central pain mechanisms but whether these normalize upon recovery is unknown. This study compared the extent of pain referral in individuals recovered from a musculoskeletal trauma and healthy controls. Twenty pain-free participants recovered from a shoulder fracture and 20 age/gender matched controls participated in two experimental sessions (Day-0, Day-1) separated by 24 hours. On both days, pressure pain thresholds (PPTs) were measured bilaterally at infraspinatus, supraspinatus, trapezius, and gastrocnemius muscles...
March 30, 2018: Pain
https://www.readbyqxmd.com/read/29602638/pattern-of-node-metastases-in-patients-treated-with-radical-cystectomy-and-extended-or-superextended-pelvic-lymph-node-dissection-due-to-bladder-cancer
#12
Marco Moschini, Emilio Arbelaez, Julian Cornelius, Agostino Mattei, Shahrokh F Shariat, Paolo Dell Oglio, Emanuele Zaffuto, Andrea Salonia, Francesco Montorsi, Alberto Briganti, Renzo Colombo, Andrea Gallina
BACKGROUND: Pelvic lymph node dissection (PLND) has a diagnostic and therapeutic role during radical cystectomy in bladder cancer patients. However, at the time, no prospective data supports the value of extended PLND in improving survival expectances. We sought to describe incidence and location of node metastases in patients treated with extended and superextended PLND. METHODS: We evaluated 653 contemporary patients with clinically nonmetastatic high risk nonmuscle invasive or muscle-invasive bladder cancer treated with radical cystectomy and extended or superextended PLND without neoadjuvant chemotherapy at a single tertiary referral center between 1990 and 2013...
March 27, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29596556/uveal-melanoma-associated-with-myotonic-dystrophy-a-report-of-6-cases
#13
Lauren A Dalvin, Carol L Shields, Jose S Pulido, Kareem Sioufi, Victoria Cohen, Jerry A Shields
Importance: Patients with myotonic dystrophy (MD) have an increased risk of malignancy including uveal melanoma. This case series further explores the association between these 2 diseases. Objective: To describe a cohort of patients with uveal melanoma associated with MD, including a case of iris melanoma, and MD-associated uveal melanoma in relatives. Design, Setting, and Participants: Retrospective case series at 3 tertiary referral centers (Wills Eye Hospital, Philadelphia, Pennsylvania; Mayo Clinic, Rochester, Minnesota; and Moorsfields Eye Hospital, London, England), between January 1, 2000, and August 31, 2017...
March 29, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29572616/tropheryma-whipplei-infection-whipple-disease-in-the-usa
#14
Isabel A Hujoel, David H Johnson, Benjamin Lebwohl, Daniel Leffler, Sonia Kupfer, Tsung-Teh Wu, Joseph A Murray, Alberto Rubio-Tapia
BACKGROUND: Whipple disease (WD) is an infection caused by the bacterium Tropheryma whipplei (TW). Few cases have been reported in the USA. AIMS: To report on the demographics, clinical manifestations, diagnostic findings, treatment, and outcomes of TW infection. METHODS: Cases of TW infection diagnosed from 1995 to 2010 were identified in three US referral centers and from 1995 to 2015 in one. Definite classic WD was defined by positive periodic acid-Schiff (PAS) staining and probable WD by specific positive TW polymerase chain reaction (PCR) of intestinal specimens...
March 23, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29565705/zygomatic-dental-implant-induced-orbital-fracture-and-inferior-oblique-trauma
#15
Ann Q Tran, Daniela P Reyes-Capó, Nimesh A Patel, Joshua Pasol, Hilda Capó, Sara T Wester
A 51-year-old female underwent four upper zygomatic dental implants (ZI) and one upper and four lower conventional implants. Immediately postoperatively, the patient had pain and diplopia upon manual elevation of the edematous eyelid. Panoramic x-ray showed a malpositioned right upper ZI, requiring removal of the right upper ZI the following day. The patient had delayed referral to ophthalmology one month later for persistent diplopia. Computed tomography scan and magnetic resonance imaging demonstrated a right inferolateral fracture with fibrosis surrounding the inferior oblique muscle...
March 22, 2018: Orbit
https://www.readbyqxmd.com/read/29563758/risk-factors-of-electrocoagulation-syndrome-after-esophageal-endoscopic-submucosal-dissection
#16
Dae Won Ma, Young Hoon Youn, Da Hyun Jung, Jae Jun Park, Jie-Hyun Kim, Hyojin Park
AIM: To investigate post endoscopic submucosal dissection electrocoagulation syndrome (PEECS) of the esophagus. METHODS: We analyzed 55 consecutive cases with esophageal endoscopic submucosal dissection for superficial esophageal squamous neoplasms at a tertiary referral hospital in South Korea. Esophageal PEECS was defined as "mild" meeting one of the following criteria without any obvious perforation: fever (≥ 37.8 °C), leukocytosis (> 10800 cells/μL), or regional chest pain more than 5/10 points as rated on a numeric pain intensity scale...
March 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29531960/lower-leg-chronic-exertional-compartment-syndrome-in-patients-50-years-of-age-and-older
#17
Johan A de Bruijn, Aniek P M van Zantvoort, Michiel B Winkes, Marike van der Cruijsen-Raaijmakers, Adwin R Hoogeveen, Joep A W Teijink, Marc R M Scheltinga
Background: Lower leg chronic exertional compartment syndrome (CECS) is usually diagnosed in young and athletic individuals. The presence of CECS in older patients has received little attention in the literature, and patient characteristics are unknown. Purpose: To determine the prevalence of CECS in older patients (≥50 years) and to assess whether older patients with CECS differ clinically from younger patients with CECS. Study Design: Cohort study; Level of evidence, 3...
March 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29508056/inspiratory-muscle-weakness-diaphragm-immobility-and-diaphragm-atrophy-after-neck-dissection
#18
Anne Flavia Silva Galindo Santana, Pedro Caruso, Pauliane Vieira Santana, Gislaine Cristina Lopes Machado Porto, Luiz Paulo Kowalski, Jose Guilherme Vartanian
BACKGROUND: Inspiratory strength after a neck dissection has not been evaluated, and diaphragm function has not been adequately evaluated. OBJECTIVE: Evaluate diaphragm mobility and inspiratory strength after neck dissection. METHODS: Prospective data collection of a consecutive series of adult patients submitted to neck dissection for head and neck cancer treatment, in a tertiary referral cancer center, from January to September 2014, with 30 days of follow-up...
May 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29499831/clinical-predictors-of-regression-of-choroidal-melanomas-after-brachytherapy-a-growth-curve-model
#19
Mamunur Rashid, Jorma Heikkonen, Arun D Singh, Tero T Kivelä
PURPOSE: To build multivariate models to assess correctly and efficiently the contribution of tumor characteristics on the rate of regression of choroidal melanomas after brachytherapy in a way that adjusts for confounding and takes into account variation in tumor regression patterns. DESIGN: Modeling of longitudinal observational data. PARTICIPANTS: Ultrasound images from 330 of 388 consecutive choroidal melanomas (87%) irradiated from 2000 through 2008 at the Helsinki University Hospital, Helsinki, Finland, a national referral center...
May 2018: Ophthalmology
https://www.readbyqxmd.com/read/29490148/double-opposing-z-plasty-for-secondary-surgical-management-of-velopharyngeal-insufficiency-following-primary-furlow-palatoplasty
#20
Arun K Gosain, Harvey Chim, Walter M Sweeney
OBJECTIVE: The present study investigates the efficacy of performing a "palate rerepair" utilizing a double-opposing z-palatoplasty (DOZ) following primary Furlow palatoplasty. DESIGN: Retrospective study. SETTING: Tertiary referral academic center for craniofacial surgery. PATIENTS: 15 consecutive patients who presented with velopharyngeal insufficiency (VPI) after primary Furlow palatoplasty. MAIN OUTCOME MEASURES: All subjects were evaluated using the perceptual speech assessment (PSA) scale...
May 2018: Cleft Palate-craniofacial Journal
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