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https://www.readbyqxmd.com/read/29792892/beef-quality-labels-a-combination-of-sensory-acceptance-test-stated-willingness-to-pay-and-choice-based-conjoint-analysis
#1
Stephan G H Meyerding, Maria Gentz, Brianne Altmann, Lisa Meier-Dinkel
Consumer perspectives of beef quality are complex, leading to a market that is increasingly differentiating. Thus, ongoing monitoring and assessment of changes in consumer perspectives is essential to identify changing market conditions. Often only credence and search characteristics are evaluated in consumer studies; therefore the object of the present study is to examine consumer preferences and perceptions towards beef steaks, also including experience characteristics, using a mixed methods approach. For this reason, 55 consumers participated in an experiment in Germany, including a sensory acceptance test, stated willingness to pay, and choice-based conjoint analysis (CBCA)...
May 21, 2018: Appetite
https://www.readbyqxmd.com/read/29792262/chronic-kidney-disease-as-a-cardiovascular-risk-factor-lessons-from-kidney-donors
#2
REVIEW
Anna M Price, Nicola C Edwards, Manvir K Hayer, William E Moody, Richard P Steeds, Charles J Ferro, Jonathan N Townend
Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease but is often associated with other risks such as diabetes and hypertension and can be both a cause and an effect of cardiovascular disease. Although epidemiologic data of an independent association of reduced glomerular filtration rate with cardiovascular risk are strong, causative mechanisms are unclear. Living kidney donors provide a useful model for assessing the "pure" effects of reduced kidney function on the cardiovascular system...
May 9, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29791738/designing-testing-and-implementing-a-sustainable-nurse-home-visiting-program-right-home
#3
Sharon Goldfeld, Anna Price, Lynn Kemp
Nurse home visiting (NHV) offers a potential platform to both address the factors that limit access to services for families experiencing adversity and provide effective interventions. Currently, the ability to examine program implementation is hampered by a lack of detailed description of actual, rather than expected, program development and delivery in published studies. Home visiting implementation remains a black box in relation to quality and sustainability. However, previous literature would suggest that efforts to both report and improve program implementation are vital for NHV to have population impact and policy sustainability...
May 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29790444/data-envelopment-analysis-for-estimating-efficiency-of-intensive-care-units-a-case-study-in-iran
#4
Mohammad Amin Bahrami, Sima Rafiei, Mahdieh Abedi, Roohollah Askari
Purpose As hospitals are the most costly service providers in every healthcare systems, special attention should be given to their performance in terms of resource allocation and consumption. The purpose of this paper is to evaluate technical, allocative and economic efficiency in intensive care units (ICUs) of hospitals affiliated by Yazd University of Medical Sciences (YUMS) in 2015. Design/methodology/approach This was a descriptive, analytical study conducted in ICUs of seven training hospitals affiliated by YUMS using data envelopment analysis (DEA) in 2015...
May 14, 2018: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/29790020/can-we-accurately-predict-cost-effectiveness-without-access-to-overall-survival-data-the-case-study-of-nivolumab-in-combination-with-ipilimumab-for-the-treatment-of-patients-with-advanced-melanoma-in-england
#5
D Lee, A Amadi, J Sabater, J Ellis, H Johnson, S Kotapati, S McNamara, A Walker, M Cooper, K Patterson, N Roskell, Y Meng
BACKGROUND: Nivolumab with ipilimumab (the Regimen) is the first immuno-oncology combination treatment to demonstrate long-term clinical benefit for advanced melanoma patients. We evaluated the cost effectiveness of the Regimen in this population, with and without the availability of overall survival (OS) data. METHODS: A partitioned survival model and a Markov state-transition model were developed to estimate the lifetime costs and benefits of the Regimen versus ipilimumab...
May 22, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29789793/modern-myoma-treatment-in-the-last-20-years-a-review-of-the-literature
#6
REVIEW
Ahmed El-Balat, Rudy Leon DeWilde, Iryna Schmeil, Morva Tahmasbi-Rad, Sandra Bogdanyova, Ali Fathi, Sven Becker
Myomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans with the highly specific process of childbirth from an upright position and the resulting need for greatly increased "expulsive" forces during labor. Myomas might be the price our species pays for our bipedal and highly intelligent existence...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29789410/a-randomised-open-label-parallel-group-phase-2-study-of-antisense-oligonucleotide-therapy-in-acromegaly
#7
Peter J Trainer, John Newell-Price, John Ayuk, Simon Aylwin, D Aled Rees, Wm Drake, Philippe Chanson, Thierry Brue, Susan M Webb, Carmen Fajardo Montañana, Javier Aller, Ann I McCormack, David J Torpy, George Tachas, Lynne Atley, David Ryder, Martin Bidlingmaier
OBJECTIVE: ATL1103 is a second-generation antisense oligomer targeting the human GH receptor. This phase 2 randomised, open-label, parallel-group study assessed the potential of ATL1103 as a treatment for acromegaly. DESIGN: 26 patients with active acromegaly (IGF-I >130% upper limit of normal) were randomised to subcutaneous ATL1103 200 mg either once- or twice-weekly for 13 weeks, and monitored for a further 8-week washout period. METHODS: The primary efficacy measures were change in IGF-I at week 14, compared to baseline and between cohorts...
May 22, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29789372/atraumatic-pencil-point-versus-conventional-needles-for-lumbar-puncture-a-clinical-practice-guideline
#8
Bram Rochwerg, Saleh A Almenawer, Reed A C Siemieniuk, Per Olav Vandvik, Thomas Agoritsas, Lyubov Lytvyn, Waleed Alhazzani, Patrick Archambault, Frederick D'Aragon, Pauline Darbellay Farhoumand, Gordon Guyatt, Jon Henrik Laake, Claudia Beltrán-Arroyave, Victoria McCredie, Amy Price, Christian Chabot, Tracy Zervakis, Jetan Badhiwala, Maude St-Onge, Wojciech Szczeklik, Morten Hylander Møller, Francois Lamontagne
No abstract text is available yet for this article.
May 22, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29789291/is-ontario-adding-drug-prices-to-emrs
#9
Wendy Glauser
No abstract text is available yet for this article.
May 22, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29789285/-all-my-relations-experiences-and-perceptions-of-indigenous-patients-connecting-with-indigenous-elders-in-an-inner-city-primary-care-partnership-for-mental-health-and-well-being
#10
George Hadjipavlou, Colleen Varcoe, David Tu, Jennifer Dehoney, Roberta Price, Annette J Browne
BACKGROUND: Mental health services in urban settings generally have not been adapted to serve the needs of Indigenous patients. We explored how patients' encounters with Indigenous Elders affected their overall mental health and well-being to identify therapeutic mechanisms underlying improvement. METHODS: We conducted qualitative interviews of participants enrolled in a 6-month prospective mixed-methods evaluation of a program for mental health and well-being that featured the inclusion of Elders in the direct care of Indigenous patients in an inner city primary care clinic...
May 22, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29789241/vaccines-inspiring-innovation-in-health
#11
Sonia Pagliusi, Maureen Dennehy, Hun Kim
This report covers the topics of pandemics, epidemics and partnerships, including regulatory convergence initiatives, new technologies and novel vaccines, discussed by leading public and private sector stakeholders at the 18th Annual General Meeting (AGM) of the Developing Countries Vaccine Manufacturers' Network (DCVMN). Contributions of Gavi and the vaccine industry from emerging countries to the growing global vaccine market, by improving the supply base from manufacturers in developing countries and contributing to 58% of doses, were highlighted...
May 19, 2018: Vaccine
https://www.readbyqxmd.com/read/29789116/10th-international-conference-on-managing-fatigue-managing-fatigue-to-improve-safety-wellness-and-effectiveness
#12
Jeffrey S Hickman, Richard J Hanowski, Jana Price, J Erin Mabry
No abstract text is available yet for this article.
May 19, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29788203/do-cost-containment-policies-save-money-and-influence-physicians-prescribing-behavior-lessons-from-south-korea-s-drug-policy-for-diabetes-medication
#13
Shin-On Kang, Seung Ju Kim, Sohee Park, Sung-In Jang, Eun-Cheol Park
Objective: We evaluate the effects of drug price reduction policy on pharmaceutical expenditure and prescription patterns in diabetes medication. Design: An interrupted time series study design using generalized estimating equations. Setting: This study used National Health Insurance claim data from 2010 to 2013. Participants: A total of 68 127 diabetes patients and 12 465 hospitals. Intervention(s): The drug price reduction policy...
May 17, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29787926/examining-community-and-consumer-food-environments-for-children-an-urban-suburban-rural-comparison-in-southwestern-ontario
#14
Catherine M DuBreck, Richard C Sadler, Godwin Arku, Jason A Gilliland
The aim of this study is to evaluate how retail food environments for children in the City of London and Middlesex County, Ontario, Canada, vary according to level of urbanicity and level of socioeconomic distress. Urbanicity in this study is defined as a neighbourhood's designation as urban, suburban, or rural. We assessed community food environments (e.g., the type, location, and accessibility of food outlets) using 800m and 1600m network buffers (school zones) around all public and private elementary schools, and we calculated and compared density of junk food opportunities (JFO) (e...
May 8, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29787325/barriers-to-self-reporting-patient-safety-incidents-by-paramedics-a-mixed-methods-study
#15
Julie E Sinclair, Michael A Austin, Christopher Bourque, Jennifer Kortko, Justin Maloney, Richard Dionne, Andrew Reed, Penny Price, Lisa A Calder
BACKGROUND: A minimal amount of research exists examining the extent to which patient safety events occur within paramedicine and even fewer studies investigating patient safety systems for self-reporting by paramedics. The purpose of this study was to identify barriers to paramedic self-reporting of patient safety incidents (PSIs). METHODS: We randomly distributed paper-based surveys among 1,153 paramedics in an Ontario region in Canada. The survey described one of 5 different PSI clinical scenarios (near miss, adverse event, and minor, major or critical patient care variances) and listed 18 potential barriers to self-reporting PSIs as statements presented for rating on a 5-point Likert scale (very significant = 1 - very insignificant = 5)...
May 22, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29786159/gestational-dyslipidaemia-and-adverse-birthweight-outcomes-a-systematic-review-and-meta-analysis
#16
REVIEW
J Wang, D Moore, A Subramanian, K K Cheng, K A Toulis, X Qiu, P Saravanan, M J Price, K Nirantharakumar
BACKGROUND: Low and high birthweight is known to increase the risk of acute and longer-term adverse outcomes, such as stillbirth, infant mortality, obesity, type 2 diabetes and cardiovascular diseases. Gestational dyslipidaemia is associated with a numbers of adverse birth outcomes, but evidence regarding birthweight is still inconsistent to reliably inform clinical practice and treatment recommendations. OBJECTIVE: The aim of this study was to explore the relationship between maternal gestational dyslipidaemia and neonatal health outcomes, namely, birthweight, metabolic factors and inflammatory parameters...
May 21, 2018: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29785952/diagnostic-accuracy-of-point-of-care-natriuretic-peptide-testing-for-chronic-heart-failure-in-ambulatory-care-systematic-review-and-meta-analysis
#17
Kathryn S Taylor, Jan Y Verbakel, Benjamin G Feakins, Christopher P Price, Rafael Perera, Clare Bankhead, Annette Plüddemann
OBJECTIVE: To assess the diagnostic accuracy of point-of-care natriuretic peptide tests in patients with chronic heart failure, with a focus on the ambulatory care setting. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Ovid Medline, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Embase, Health Technology Assessment Database, Science Citation Index, and Conference Proceedings Citation Index until 31 March 2017...
May 21, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29784886/-legionella-pneumophila-is-directly-sensitive-to-2-deoxyglucose-phosphate-via-its-uhpc-transporter-but-is-indifferent-to-shifts-in-host-cell-glycolytic-metabolism
#18
Jordan V Price, Kallie Jiang, Abigail Galantowicz, Alana Freifeld, Russell E Vance
Toll-like receptor stimulation induces a pronounced shift to increased glycolytic metabolism in mammalian macrophages. We observed that bone marrow-derived macrophages (BMMs) increase glycolysis in response to infection with Legionella pneumophila ( L. pneumophila ), but the role of host macrophage glycolysis on intracellular L. pneumophila replication is not currently understood. Treatment with 2-deoxyglucose (2DG) blocks L. pneumophila replication in mammalian macrophages but has no effect on bacteria grown in broth...
May 21, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29784809/correction-for-vaidyanathan-core-concept-microgrids-offer-flexible-energy-generation-for-a-price
#19
(no author information available yet)
No abstract text is available yet for this article.
May 21, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29784696/why-are-we-failing-to-address-the-issue-of-access-to-insulin-a-national-and-global-perspective
#20
David Beran, Irl B Hirsch, John S Yudkin
Insulin was discovered in 1921 and soon became widely available in high-income countries. However, many people currently in need of this life-saving medicine are unable to access it. This is a global phenomenon, impacting not only populations of low- and middle-income countries but low-income populations in the U.S. In the U.S., the rate of diabetic ketoacidosis remains high in certain subpopulations, the cost of insulin being the main precipitating factor. On a global level the main cause of mortality for a child with type 1 diabetes is a lack of access to insulin, and in sub-Saharan Africa the life expectancy of a child with type 1 diabetes can be as low as 1 year...
June 2018: Diabetes Care
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