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https://www.readbyqxmd.com/read/29149579/doing-for-the-greater-good-what-price-in-academe
#1
Suniya S Luthar
In discussing how merit is commonly judged in academia, my focus in this article is not on dimensions that are currently considered but on those that warrant more attention. Grounded in suggestions offered by Sternberg, I argue here for increased recognition of faculty's commitment to intrinsic values-focused on community and relationships-and not just extrinsic ones that connote personal fame or status. I first summarize evidence of disillusionment among today's promising young scholars and then provide exemplars of role models who have, in fact, maintained high standards in both intrinsic and extrinsic domains...
November 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29149448/crisis-in-the-country
#2
Sean Price
Since 2010, Texas has seen more rural hospitals close than has any other state, leaving huge gaps in health care; however, the state's rural areas have options for maintaining health care facilities.
November 1, 2017: Texas Medicine
https://www.readbyqxmd.com/read/29149446/a-flood-of-problems
#3
Sean Price
Hurricane Harvey devastated the Texas coast in late August. Widespread flooding in the Houston area wiped out thousands of homes and businesses, including countless medical facilities and practices. Although the short-term health concerns may be apparent, longer-term effects associated with stress and environmental issues can be harder to spot.
November 1, 2017: Texas Medicine
https://www.readbyqxmd.com/read/29149220/a-novel-method-to-rapidly-distinguish-the-geographical-origin-of-traditional-fermented-salted-vegetables-by-mass-fingerprinting
#4
So-Ra Yoon, Sung Hyun Kim, Hae-Won Lee, Ji-Hyoung Ha
The geographical origin of kimchi is of interest to consumers and producers because the prices of commercial kimchi products can vary significantly according to the geographical origin. Hence, social issues related to the geographical origin of kimchi in Korea have emerged as a major problem. In this study, the geographical origin of kimchi was determined by comparing the mass fingerprints obtained for Korean and Chinese kimchi samples by MALDI-TOF MS with multivariate analysis. The results obtained herein provide an accurate, powerful tool to clearly discriminate kimchi samples based on their geographical origin within a short time and to ensure food authenticity, which is of significance in the kimchi industry...
2017: PloS One
https://www.readbyqxmd.com/read/29148854/comparative-effectiveness-of-lipid-lowering-treatments-to-reduce-cardiovascular-disease
#5
Dong-Churl Suh, Scott K Griggs, Emmett R Henderson, Seung-Mi Lee, Taehwan Park
With the advent of a new drug class - the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, patients have another treatment option for lowering their high levels of low-density lipoprotein cholesterol (LDL-C) in recent years. The objective of this study was to systematically review the cost-effectiveness of lipid-lowering agents such as statins, ezetimibe, and PCSK9 inhibitors. Areas covered: Based on PubMed, Embase, and Cochrane Database of Systematic Reviews, we identified a total of 29 relevant articles...
November 17, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29148355/vertical-integration-of-hospitals-and-physicians-economic-theory-and-empirical-evidence-on-spending-and-quality
#6
Brady Post, Tom Buchmueller, Andrew M Ryan
Hospital-physician vertical integration is on the rise. While increased efficiencies may be possible, emerging research raises concerns about anticompetitive behavior, spending increases, and uncertain effects on quality. In this review, we bring together several of the key theories of vertical integration that exist in the neoclassical and institutional economics literatures and apply these theories to the hospital-physician relationship. We also conduct a literature review of the effects of vertical integration on prices, spending, and quality in the growing body of evidence ( n = 15) to evaluate which of these frameworks have the strongest empirical support...
August 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29148350/economic-conditions-and-drug-and-opioid-overdose-deaths
#7
Ezequiel Brown, George L Wehby
We examine the effects of state-level economic conditions including unemployment rates, median house price, median household income, insurance coverage, and annual and weekly work time on deaths on drug overdose deaths including from opioids and prescription opioids between 1999 and 2014. We employ difference-in-differences estimation controlling for state and year fixed effects, state-specific time trends, and demographic characteristics. Drug overdose deaths significantly declined with higher house prices, an effect driven by reduction in prescription-opioid mortality, by nearly 0...
July 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29148343/lessons-learned-from-the-affordable-care-act-the-premium-subsidy-design-may-promote-adverse-selection
#8
Ilana Graetz, Caitlin N McKillop, Cameron M Kaplan, Teresa M Waters
Since 2014, average premiums for health plans available in the Affordable Care Act marketplaces have increased. We examine how premium price changes affected the amount consumers pay after subsidies for the lowest-cost bronze and silver plans available by age in the federally facilitated exchanges. Between 2015 and 2016, benchmark plan premiums increased in 83.3% of counties. Overall, rising benchmark premiums were associated with lower average after-subsidy premiums for the lowest-cost bronze and silver plans for older subsidy-eligible adults, but with higher after-subsidy premiums for younger adults purchasing the same plans, regardless of income...
May 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29148327/are-integrated-plan-providers-associated-with-lower-premiums-on-the-health-insurance-marketplaces
#9
Ambar La Forgia, Jared Lane K Maeda, Jessica S Banthin
As the health insurance industry becomes more consolidated, hospitals and health systems have started to enter the insurance business. Insurers are also rapidly acquiring providers. Although these "vertically" integrated plan providers are small players in the insurance market, they are becoming more numerous. The health insurance marketplaces (HIMs) offer a unique setting to study integrated plan providers relative to other insurer types because the HIMs were designed to promote competition. In this descriptive study, the authors compared the premiums of the lowest priced silver plans of integrated plan providers with other insurer types on the 2015 and 2016 HIMs...
February 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29147575/cell-death-and-cell-lysis-are-separable-events-during-pyroptosis
#10
Lucian DiPeso, Daisy X Ji, Russell E Vance, Jordan V Price
Although much insight has been gained into the mechanisms by which activation of the inflammasome can trigger pyroptosis in mammalian cells, the precise kinetics of the end stages of pyroptosis have not been well characterized. Using time-lapse fluorescent imaging to analyze the kinetics of pyroptosis in individual murine macrophages, we observed distinct stages of cell death and cell lysis. Our data demonstrate that cell membrane permeability resulting from gasdermin D pore formation is coincident with the cessation of cell movement, loss of mitochondrial activity, and cell swelling, events that can be uncoupled from cell lysis...
2017: Cell Death Discovery
https://www.readbyqxmd.com/read/29147089/multiple-regression-analysis-to-estimate-the-unit-price-of-hanwoo-bos-taurus-coreanae-beef
#11
Seung-Hoon Eum, Hu-Rak Park, Jakyeom Seo, Seong-Keun Cho, Sun-Jin Hur, Byeong-Woo Kim
This study were estimated the contribution of carcass traits to unit price, to analyze the marbling score as a categorical variable rather than a numerical variable, and to develop an optimal model that also includes the holiday effect and the raising period. The data for this study were acquired from the Quality Evaluation of the Korea Institute for Animal Products, and consisted of the trading records of 1,613,699 heads at 12 wholesale markets from 2010 to 2014. The unit price of a cow was estimated from the following parameters: -52...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29146460/the-impact-of-price-and-nutrition-labelling-on-sugary-drink-purchases-results-from-an-experimental-marketplace-study
#12
Rachel B Acton, David Hammond
OBJECTIVE: To examine the effect of front-of-package (FOP) nutrition labelling and sugary drink taxation on consumer beverage purchases. METHODS: A total of 675 respondents aged 16 years and older participated in an experimental marketplace study using a 4 × 5 within-between group design. Participants were randomised to one of four labelling conditions (no label; star rating; high sugar symbol; health warning) and completed five within-subject purchase tasks...
November 13, 2017: Appetite
https://www.readbyqxmd.com/read/29146160/posterolateral-corner-injuries-of-the-knee-at-the-national-football-league-combine-an-imaging-and-outcomes-analysis
#13
Jorge Chahla, Nicholas I Kennedy, Mark E Cinque, George Sanchez, Catherine Logan, Bryan G Vopat, Brendin Beaulieu-Jones, Mark Price, Jim Whalen, Robert F LaPrade, Matthew T Provencher
PURPOSE: (1) To determine the epidemiology, examination findings, imaging findings, and associated injuries of posterolateral corner (PLC) injuries in players participating in the National Football League (NFL) Combine and (2) to evaluate the impact of PLC injuries on performance compared with matched controls. METHODS: All PLC injuries identified at the NFL Combine between 2009 and 2015 were reviewed. The inclusion criteria were any player who had clinical findings or a previous surgical procedure consistent with a PLC injury and who participated in medical and performance testing at the NFL Combine...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145660/acca-escel
#14
Susanna Price
No abstract text is available yet for this article.
November 14, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29144866/challenges-in-the-clinical-application-of-the-american-society-of-clinical-oncology-value-framework-a-medicare-cost-benefit-analysis-in-chronic-lymphocytic-leukemia
#15
Erlene K Seymour, Charles A Schiffer, Jonas A de Souza
PURPOSE: The ASCO Value Framework calculates the value of cancer therapies. Given costly novel therapeutics for chronic lymphocytic leukemia, we used the framework to compare net health benefit (NHB) and cost within Medicare of all regimens listed in the National Comprehensive Cancer Network (NCCN) guidelines. METHODS: The current NCCN guidelines for chronic lymphocytic leukemia were reviewed. All referenced studies were screened, and only randomized controlled prospective trials were included...
November 16, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29144742/successful-identification-of-cardiac-troponin-calcium-sensitizers-using-a-combination-of-virtual-screening-and-roc-analysis-of-known-troponin-c-binders
#16
Melanie L Aprahamian, Svetlana B Tikunova, Morgan V Price, Andres F Cuesta, Jonathan P Davis, Steffen Lindert
Calcium-dependent cardiac muscle contraction is regulated by the protein complex troponin. Calcium binds to the N-terminal domain of troponin C (cNTnC) which initiates the process of contraction. Heart failure is a consequence of a disruption of this process. With the prevalence of this condition, a strong need exists to find novel compounds to increase the calcium sensitivity of cNTnC. Desirable are small chemical molecules that bind to the interface between cTnC and the cTnI switch peptide and exhibit calcium sensitizing properties by possibly stabilizing cTnC in an open conformation...
November 16, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29144387/neighborhood-prices-of-healthier-and-unhealthier-foods-and-associations-with-diet-quality-evidence-from-the-multi-ethnic-study-of-atherosclerosis
#17
David M Kern, Amy H Auchnicloss, Mark F Stehr, Ana V Diez Roux, Latetia V Moore, Genevieve P Kanter, Lucy F Robinson
It is known that the price of food influences the purchasing and consumption decisions of individuals; however, little work has examined if the price of healthier food relative to unhealthier food in an individual's neighborhood is associated with overall dietary quality while using data from multiple regions in the United States. Cross-sectional person-level data came from The Multi-Ethnic Study of Atherosclerosis (exam 5, 2010-2012 n = 2765); a food frequency questionnaire assessed diet. Supermarket food/beverage prices came from Information Resources Inc...
November 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29144113/-can-we-transfer-the-mechanisms-of-the-generics-market-to-biosimilars
#18
Ch O Jacke, F Wild
Personalized medicines such as biologics and their generic equivalents, biosimilars, are pouring onto the pharmaceutical markets. Data of 16 private health insurance companies were used to describe the market shares of selected biosimilars available in 2014 and 2015. The purpose of this study focuses on the question of whether market access of biosimilars will lead to a price competition of the expense of innovation competition. The results show that prescriptions of biosimilars made up 37% of total prescriptions in 2015 compared to 35% in 2014, and that their share of prescription costs went up from 21% to 23% in the same period...
December 15, 2016: Versicherungsmedizin
https://www.readbyqxmd.com/read/29143711/defining-the-breeding-goal-for-a-sheep-breed-including-production-and-functional-traits-using-market-data
#19
A Theodoridis, A Ragkos, G Rose, D Roustemis, G Arsenos
In this study, the economic values for production and functional traits of dairy sheep are estimated through the application of a profit function model using farm-level technical and economic data. The traits incorporated in the model were milk production, prolificacy, fertility, milking speed, longevity and mastitis occurrence. The economic values for these traits were derived as the approximate partial derivative of the specified profit function. A sensitivity analysis was also conducted in order to examine how potential changes in input and output prices would affect the breeding goal...
November 16, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29143620/optimising-diagnosis-of-viraemic-hepatitis-c-infection-the-development-of-a-target-product-profile
#20
Elena Ivanova Reipold, Philippa Easterbrook, Alessandra Trianni, Nivedha Panneer, Douglas Krakower, Stefano Ongarello, Teri Roberts, Veronica Miller, Claudia Denkinger
BACKGROUND: The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance on the optimal characteristics a virological test needs to have to ensure the greatest impact on HCV diagnosis and treatment in LMIC. Our objective was to develop a target product profile (TPP) for diagnosis of HCV viraemia using a global stakeholder consensus-based approach...
November 1, 2017: BMC Infectious Diseases
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