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https://www.readbyqxmd.com/read/29245188/the-unmet-needs-of-aboriginal-australians-with-musculoskeletal-pain-a-mixed-method-systematic-review
#1
Ivan B Lin, Samantha Bunzli, Donna B Mak, Charmaine Green, Roger Goucke, Juli Coffin, Peter B O'Sullivan
OBJECTIVE: Musculoskeletal pain (MSP) conditions are the biggest cause of disability and internationally, Indigenous peoples experience a higher burden. There are conflicting reports about Aboriginal Australians and MSP. We conducted a systematic review to describe the prevalence, associated factors, impacts, care access, health care experiences, and factors associated with MSP among Aboriginal Australians. METHODS: A systematic search of quantitative and qualitative scientific and grey literature (PROSPERO number: CRD42016038342)...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245186/endothelial-dysfunction-in-early-systemic-lupus-erythematosus-patients-and-controls-without-previous-cardiovascular-events
#2
Mara Taraborelli, Edoardo Sciatti, Ivano Bonadei, Vincenzo Terlizzi, Micaela Fredi, Roberta Zani, Giovanni Cancarini, Angela Tincani, Franco Franceschini, Enrico Vizzardi, Ilaria Cavazzana
OBJECTIVES: To assess the prevalence and risk factors for endothelial dysfunction detected by peripheral artery tonometry in systemic lupus erythematosus patients with early disease without cardiovascular disease and risk factors. METHODS: All the consecutive adult lupus patients, with a disease duration less than 5 years, seen in our Hospital from December 2014 to March 2016 were considered. We excluded patients with any history of cardiovascular disease or risk factors possibly affecting peripheral artery tonometry...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245185/contribution-of-crop-model-structure-parameters-and-climate-projections-to-uncertainty-in-climate-change-impact-assessments
#3
Fulu Tao, Reimund P Rötter, Taru Palosuo, C G H Díaz-Ambrona, M Inés Mínguez, Mikhail A Semenov, Kurt Christian Kersebaum, Claas Nendel, Xenia Specka, Holger Hoffmann, Frank Ewert, Anaelle Dambreville, Pierre Martre, Lucía Rodríguez, Margarita Ruiz-Ramos, Thomas Gaiser, Jukka G Höhn, Tapio Salo, Roberto Ferrise, Marco Bindi, Davide Cammarano, Alan H Schulman
Climate change impact assessments are plagued with uncertainties from many sources, such as climate projections or the inadequacies in structure and parameters of the impact model. Previous studies tried to account for the uncertainty from one or two of these. Here, we developed a triple-ensemble probabilistic assessment using seven crop models, multiple sets of model parameters, and eight contrasting climate projections together to comprehensively account for uncertainties from these three important sources...
December 15, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29245183/increased-expression-and-modulated-regulatory-activity-of-co-inhibitory-receptors-pd-1-tigit-and-tim-3-in-lymphocytes-of-systemic-sclerosis-patients
#4
Michelle Fleury, Anna C Belkina, Elizabeth A Proctor, Christopher Zammitti, Robert W Simms, Douglas A Lauffenburger, Jennifer E Snyder-Cappione, Robert Lafyatis, Hans Dooms
OBJECTIVE: Immune dysfunction is an important component of the disease process underlying Systemic Sclerosis (SSc), but the mechanisms contributing to altered immune cell function in SSc remain poorly defined. Here, we measured the expression and function of the co-inhibitory receptors (co-IRs) PD-1, TIGIT, TIM-3, and LAG-3 in lymphocyte subsets from the peripheral blood of SSc patients. METHODS: Co-IR expression levels on immune cell subsets were analyzed using a 16-color flow cytometry panel...
December 15, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29245179/hot-off-the-press-sgem-196-gastroparesis-i-feel-like-throwing-up
#5
Corey Heitz, Justin Morgenstern, William K Milne
This randomized controlled trial compared haloperidol along with conventional therapy to placebo along with conventional therapy for gastroparesis in the emergency department. The primary outcomes of pain and nausea scores at 1 hour were significantly improved in the haloperidol group, but not in the placebo group. In this summary, we discuss a quality assessment of the article and summarized the social media commentary from the blog post/podcast. This article is protected by copyright. All rights reserved.
December 15, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29245167/-are-we-really-as-happy-as-we-think-we-are-a-critical-examination-of-work-satisfaction-in-a-university-pediatric-hospital
#6
Andreas Hiemisch, Yve Stöbel-Richter, Gesine Grande, Elmar Brähler, Wieland Kiess
Goals Despite numerous reported deficits and an increasingly tense working environment in German hospitals, employees themselves often assess their job satisfaction as being high to very high. Hence, the board of directors does not have important arguments for sustainable improvement of working conditions. This discrepancy between working conditions and subjective satisfaction was the motivation for this work. Methods Data were acquired via an attitude survey at the University Hospital for Children and Adolescents Leipzig, with employees sub-divided into medical, nursing and administrative/technical staff...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29245158/-intrapartum-translabial-ultrasound-a-systematic-analysis-of-the-fetal-head-station-in-the-first-stage-of-labor
#7
Fabian Kohls, Lars Brodowski, Elna Kuehnle, Nadine Kniebusch, Karim Djaffar Kalache, Alexander Weichert
Introduction This prospective study aimed to define the angle of progression (AOP) in relation to the height position of the fetal head during the first stage of labour. It was investigated if it is possible to predict the mode of delivery or the duration of labour by AOP. Methods Influencing factors on delivery were head circumference, birth-weight, administration of oxytocin, epidural anaesthesia (EA) and parity, and their impact on AOP was analysed. AOP was calculated using three different formulas. Inclusion criteria were vaginal delivery of singletons in cephalic, occipito-anterior presentation...
December 15, 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/29245154/acute-procedural-outcomes-of-orbital-atherectomy-for-the-treatment-of-profunda-femoris-artery-disease-subanalysis-of-the-confirm-registries
#8
Michael S Lee, Pratyaksh K Srivastava, Saif Al Yaseen, Daniel Heikali, John Hollowed, Ehtisham Mahmud
OBJECTIVES: We compared the angiographic outcomes of patients treated with orbital atherectomy for profunda femoris artery (PFA) and superficial femoral artery (SFA) disease from the CONFIRM I-III registries. BACKGROUND: Endovascular revascularization of the PFA is considered a high-risk procedure given that it is an important collateral vessel when the SFA becomes occluded. Data on outcomes of endovascular revascularization of calcified PFA disease are limited...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245153/catheter-ablation-of-focal-atrial-tachycardia-using-remote-magnetic-navigation
#9
Xiao-Yu Liu, Peter Karl Jacobsen, Steen Pehrson, Xu Chen
OBJECTIVES: The outcomes of catheter ablation in focal atrial tachycardia (AT) using remote magnetic navigation (RMN) are still controversial. The objectives of this study were to assess the acute and long-term outcomes of catheter ablation in focal AT using RMN. BACKGROUND: A total of 53 patients with focal AT who underwent catheter ablation using RMN were included. Thirty-six patients had structural heart disease, including previous atrial fibrillation ablation and heart surgery (abnormal group), and the remaining 17 patients had no structural heart disease (normal group)...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245152/operator-pelvic-radiation-exposure-during-percutaneous-coronary-procedures
#10
Alessandro Sciahbasi, Emanuela Piccaluga, Alessandro Sarandrea, Giacomo Nucci, Nicola Caretto, Stefano Rigattieri, Silvio Fedele, Silvio Romano, Maria Penco
OBJECTIVES: To evaluate operator pelvic radiation exposure during percutaneous coronary procedures. BACKGROUND: During percutaneous coronary procedures, the operator's pelvic region is close to the x-ray source and is probably exposed to more radiation than the operator's thorax. However, no data are available on the pelvic radiation exposure of interventional cardiologists. METHODS: The RADIANT study (NCT01974453) is a prospective, single-center, observational study evaluating operator radiation exposure during percutaneous coronary procedures using electronic dosimeters placed at thorax level...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245149/organorelease-a-framework-for-modeling-the-release-of-organic-chemicals-from-the-use-and-post-use-of-consumer-products
#11
Mengya Tao, Dingsheng Li, Runsheng Song, Sangwon Suh, Arturo A Keller
Chemicals in consumer products have become the focus of recent regulatory developments including California's Safer Consumer Products Act. However, quantifying the amount of chemicals released during the use and post-use phases of consumer products is challenging, limiting the ability to understand their impacts. Here we present a comprehensive framework, OrganoRelease, for estimating the release of organic chemicals from the use and post-use of consumer products given limited information. First, a novel Chemical Functional Use Classifier estimates functional uses based on chemical structure...
December 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29245145/comparative-leaching-of-six-toxic-metals-from-raw-and-chemically-stabilized-mswi-fly-ash-using-citric-acid
#12
Huawei Wang, Xinxiu Fan, Ya-Nan Wang, Weihua Li, Yingjie Sun, Meili Zhan, Guizhi Wu
The leaching behavior of six typical toxic metals (Pb, Zn, Cr, Cd, Cu and Ni) from raw and chemically stabilized (phosphate and chelating agent) municipal solid waste incineration (MSWI) fly ash were investigated using citric acid. Leaching tests indicated that phosphate stabilization can effectively decrease the leaching of Zn, Cd and Cr; whereas chelating agent stabilization shows a strong ability to lower the release of Pb, Cd and Cu, but instead increases the solubility of Zn and Cr at low pH conditions...
December 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29245140/school-readiness-of-maltreated-children-associations-of-timing-type-and-chronicity-of-maltreatment
#13
Megan F Bell, Donna M Bayliss, Rebecca Glauert, Jeneva L Ohan
Children who have been maltreated during early childhood may experience a difficult transition into fulltime schooling, due to maladaptive development of the skills and abilities that are important for positive school adaptation. An understanding of how different dimensions of maltreatment relate to children's school readiness is important for informing appropriate supports for maltreated children. In this study, the Australian Early Development Census scores of 19,203 children were linked to information on child maltreatment allegations (substantiated and unsubstantiated), including the type of alleged maltreatment, the timing of the allegation (infancy-toddlerhood or preschool), and the total number of allegations (chronicity)...
December 11, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29245135/acidogenic-fermentation-of-iron-enhanced-primary-sedimentation-sludge-under-different-ph-conditions-for-production-of-volatile-fatty-acids
#14
Lin Lin, Xiao-Yan Li
Iron-based chemically enhanced primary sedimentation (CEPS) is increasingly adopted for wastewater treatment in mega cities, producing a large amount of sludge (Fe-sludge) with a high content of organics for potential organic resource recovery. In this experimental study, acidogenic fermentation was applied treat FeCl3-based CEPS sludge for production of volatile fatty acids (VFAs) at different pHs. Batch fermentation tests on the Fe-sludge with an organic content of 10 g-COD/L showed that the maximum VFAs production reached 2782...
December 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/29245130/biodiesel-production-from-castor-oil-using-heterogeneous-ni-doped-zno-nanocatalyst
#15
G Baskar, I Aberna Ebenezer Selvakumari, R Aiswarya
In the present study, castor oil with high free fatty acid was used for biodiesel production using heterogeneous Ni doped ZnO nanocatalyst. Ni doped ZnO nanocomposite calcinated at 800 °C has shown better catalytic activity. Process parameters on heterogeneous catalysis of castor oil into biodiesel were optimized using conventional and Response Surface Methodology (RSM). RSM was found more accurate in estimating the optimum conditions with higher biodiesel yield (95.20%). The optimum conditions for transesterification was found to be oil to methanol molar ratio of 1:8, catalyst loading 11% (w/w), reaction temperature of 55 °C for 60 min of reaction time by response surface method...
December 8, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29245129/a-novel-approach-of-modeling-continuous-dark-hydrogen-fermentation
#16
Maria Alexandropoulou, Georgia Antonopoulou, Gerasimos Lyberatos
In this study a novel modeling approach for describing fermentative hydrogen production in a continuous stirred tank reactor (CSTR) was developed, using the Aquasim modeling platform. This model accounts for the key metabolic reactions taking place in a fermentative hydrogen producing reactor, using fixed stoichiometry but different reaction rates. Biomass yields are determined based on bioenergetics. The model is capable of describing very well the variation in the distribution of metabolic products for a wide range of hydraulic retention times (HRT)...
December 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29245128/anaerobic-accumulation-of-short-chain-fatty-acids-from-algae-enhanced-by-damaging-cell-structure-and-promoting-hydrolase-activity
#17
Leiyu Feng, Yunzhi Chen, Xutao Chen, Xu Duan, Jing Xie, Yinguang Chen
Short-chain fatty acid (SCFAs) produced from harvested algae by anaerobic fermentation with uncontrolled pH was limited due to the solid cell structure of algae. This study, therefore, was undertaken to enhance the generation of SCFAs from algae by controlling the fermentation pH. pH influenced not only the total SCFAs production, but the percentage of individual SCFA. The maximal yield of SCFAs occurred at pH 10.0 and fermentation time of 6 d (3161 mg COD/L), which mainly contained acetic and iso-valeric acids and was nearly eight times that at uncontrolled pH (392 mg COD/L)...
December 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29245126/geographic-and-social-disparities-in-exposure-to-air-neurotoxicants-at-u-s-public-schools
#18
Sara E Grineski, Timothy W Collins
Children are especially vulnerable to the health and developmental impacts of environmental hazards and they spend significant portions of their days at school. Yet there are no national-level studies examining school-level environmental inequalities and few have examined disparate exposure to neurological air toxicants, even though chronic exposure to air pollution impacts children's brain functioning. We paired information about the geographic locations and demographics of each public school in the US with air neurotoxicant exposure estimates pertaining to 24 known neurotoxicants included in the US Environmental Protection Agency's National Air Toxics Assessment...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29245124/bisphenol-and-phthalate-concentrations-and-its-determinants-among-pregnant-women-in-a-population-based-cohort-in-the-netherlands-2004-5
#19
Elise M Philips, Vincent W V Jaddoe, Alexandros G Asimakopoulos, Kurunthachalam Kannan, Eric A P Steegers, Susana Santos, Leonardo Trasande
BACKGROUND: Exposure to bisphenols and phthalates in pregnancy may lead to adverse health effects in women themselves and their offspring. OBJECTIVE: To describe first trimester bisphenol and phthalate urine concentrations, including bisphenol and phthalate replacements, and determine nutritional, socio-demographic and lifestyle related determinants. METHODS: In a population-based prospective cohort of 1396 mothers, we measured first trimester bisphenol, phthalate and creatinine urine concentrations (samples collected in 2004-2005, median gestational age 12...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29245122/reduction-of-cancer-cell-viability-by-synergistic-combination-of-photodynamic-treatment-with-the-inhibition-of-the-id-protein-family
#20
Cornelia Roschger, Thomas Verwanger, Barbara Krammer, Chiara Cabrele
The inhibitor of DNA binding and cell differentiation (Id) proteins are dominant negative regulators of the helix-loop-helix transcription factor family and play a key role during development as well as in vascular disorders and cancer. In fact, impairing the Id-protein activity in cancer cells reduces cell growth and even chemoresistance. Recently, we have shown that a synthetic Id-protein ligand (1Y) consisting of a cyclic nonapeptide can reduce the viability of the two breast cancer cell lines MCF-7 and T47D and of the bladder cancer cells T24 to about 50% at concentrations ≥100μM...
December 5, 2017: Journal of Photochemistry and Photobiology. B, Biology
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