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https://www.readbyqxmd.com/read/27876658/stenting-for-carotid-web-a-case-report
#1
R Martínez-Pérez, S P Lownie, S Pandey, M R Boulton
BACKGROUND: The carotid web is an intraluminal shelf-like projection arising from the posterior wall of the carotid bifurcation, and is an uncommon etiology of ischemic strokes. Our objective is to describe the feasibility of endovascular stenting to treat this condition CASE REPORT: In a 47-year-old female with a sudden occlusion of her right middle cerebral artery. CT angiogram and digital subtraction angiography showed the presence of a carotid web in the ipsilateral carotid bifurcation...
November 19, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27864523/carotid-artery-web-and-ischemic-stroke-a-case-control-study
#2
Jonathan M Coutinho, Sheldon Derkatch, Alphonse R J Potvin, George Tomlinson, Leanne K Casaubon, Frank L Silver, Daniel M Mandell
OBJECTIVE: To determine whether there is an association between carotid artery web and ischemic stroke. METHODS: This was a single-center, age- and sex-matched, case-control study. Cases were consecutive patients with anterior circulation ischemic stroke of undetermined etiology (Trial of Org 10172 in Acute Stroke Treatment [TOAST] classification). Controls were consecutive patients with cerebral aneurysms, arteriovenous malformations, or primary intracerebral hemorrhages...
November 18, 2016: Neurology
https://www.readbyqxmd.com/read/27859887/preclinical-atherosclerosis-at-the-time-of-pre-eclamptic-pregnancy-and-up-to-10-years-postpartum-systematic-review-and-meta-analysis
#3
REVIEW
Natasa M Milic, Jelena Milin-Lazovic, Tracey L Weissgerber, Goran Trajkovic, Wendy M White, Vesna D Garovic
OBJECTIVES: Preeclampsia, a pregnancy-specific hypertensive disorder, has been associated with cardiovascular risk factors and vascular changes, such as acute atherosis in placental blood vessels, which are similar to early-stage atherosclerosis. The objective of this study was to determine whether women with preeclampsia have increased atherosclerotic burden, as determined by carotid intima-media thickness (CIMT), when compared to women without preeclampsia. METHODS: We conducted a systematic review and meta-analysis of studies that reported CIMT, a non-invasive, ultrasound-based measure of subclinical atherosclerosis, in women who did vs...
November 18, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27763781/markers-of-atherosclerosis-in-patients-with-cushing-s-syndrome-a-meta-analysis-of-literature-studies
#4
Roberta Lupoli, Pasquale Ambrosino, Anna Tortora, Livia Barba, Gelsy Arianna Lupoli, Matteo Nicola Dario Di Minno
BACKGROUND: Several studies reported an increased cardiovascular (CV) risk in Cushing's syndrome (CS). We performed a meta-analysis on the impact of CS on major markers of atherosclerosis. METHODS: Studies on intima-media thickness (IMT), carotid plaques prevalence and flow-mediated dilation (FMD) in CS patients and controls were searched in the PubMed, Web of Science, Scopus and EMBASE. Differences between cases and controls were expressed as mean difference (MD) with 95% confidence intervals (95%CI) for continuous variables, and as Odds Ratio (OR) with 95%CI for dichotomous variables...
October 20, 2016: Annals of Medicine
https://www.readbyqxmd.com/read/27399394/114%C3%A2-treatment-of-bifurcation-aneurysms-using-single-stent-coiling-with-relation-to-aneurysm-configuration-a-cohort-study-of-two-academic-institutions-in-the-united-states
#5
Nimer Adeeb, Apar S Patel, Christoph Johannes Griessenauer, Justin M Moore, Paul M Foreman, Raghav Gupta, Mark R Harrigan, Christopher S Ogilvy, Ajith J Thomas
INTRODUCTION: Stent-coiling of bifurcation aneurysms has significantly expanded the spectrum of aneurysms amenable to endovascular therapy. A variety of techniques have evolved to deal with wide-necked bifurcation aneurysms such as Y-stenting and WEB embolization device. In our 2 institutions, we have primarily used a single stent coiling to treat most bifurcation aneurysms. We present a large series in which a single stent was utilized with angiographic and clinical outcomes. METHODS: Two academic institutions in the United States contributed prospectively maintained data on consecutive patients with bifurcation aneurysms treated with single stent coiling between 2007 and 2015...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27369488/rationale-and-design-of-the-baptist-employee-healthy-heart-study-a-randomized-trial-assessing-the-efficacy-of-the-addition-of-an-interactive-personalized-web-based-lifestyle-intervention-tool-to-an-existing-health-information-web-platform-in-a-high-risk-employee
#6
Janisse M Post, Shozab S Ali, Lara L Roberson, Ehimen C Aneni, Sameer Shaharyar, Adnan Younus, Omar Jamal, Rameez Ahmad, Muhammad A Aziz, Rehan Malik, Erica S Spatz, Theodore Feldman, Jonathan Fialkow, Emir Veledar, Ricardo C Cury, Arthur S Agatston, Khurram Nasir
BACKGROUND: Metabolic syndrome (MetS) and diabetes confer a high risk for developing subsequent cardiovascular disease (CVD). Persons with MetS constitute 24-34 % of the employee population at Baptist Health South Florida (BHSF), a self-insured healthcare organization. The Baptist Employee Healthy Heart Study (BEHHS) aims to assess the addition of a personalized, interactive, web-based, nutrition-management and lifestyle-management program to the existing health-expertise web platform available to BHSF employees in reducing and/or stabilizing CVD and lifestyle risk factors and markers of subclinical CVD...
2016: Trials
https://www.readbyqxmd.com/read/27341046/stent-deployment-protocol-for-optimized-real-time-visualization-during-endovascular-neurosurgery
#7
Michael A Silva, Alfred P See, Hormuzdiyar H Dasenbrock, Ramsey Ashour, Priyank Khandelwal, Nirav J Patel, Kai U Frerichs, Mohammad A Aziz-Sultan
Successful application of endovascular neurosurgery depends on high-quality imaging to define the pathology and the devices as they are being deployed. This is especially challenging in the treatment of complex cases, particularly in proximity to the skull base or in patients who have undergone prior endovascular treatment. The authors sought to optimize real-time image guidance using a simple algorithm that can be applied to any existing fluoroscopy system. Exposure management (exposure level, pulse management) and image post-processing parameters (edge enhancement) were modified from traditional fluoroscopy to improve visualization of device position and material density during deployment...
June 24, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27338146/knowledge-author-facilitating-user-driven-domain-content-development-to-support-clinical-information-extraction
#8
William Scuba, Melissa Tharp, Danielle Mowery, Eugene Tseytlin, Yang Liu, Frank A Drews, Wendy W Chapman
BACKGROUND: Clinical Natural Language Processing (NLP) systems require a semantic schema comprised of domain-specific concepts, their lexical variants, and associated modifiers to accurately extract information from clinical texts. An NLP system leverages this schema to structure concepts and extract meaning from the free texts. In the clinical domain, creating a semantic schema typically requires input from both a domain expert, such as a clinician, and an NLP expert who will represent clinical concepts created from the clinician's domain expertise into a computable format usable by an NLP system...
2016: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/27318571/accurate-cloud-based-smart-imt-measurement-its-validation-and-stroke-risk-stratification-in-carotid-ultrasound-a-web-based-point-of-care-tool-for-multicenter-clinical-trial
#9
Luca Saba, Sumit K Banchhor, Harman S Suri, Narendra D Londhe, Tadashi Araki, Nobutaka Ikeda, Klaudija Viskovic, Shoaib Shafique, John R Laird, Ajay Gupta, Andrew Nicolaides, Jasjit S Suri
This study presents AtheroCloud™ - a novel cloud-based smart carotid intima-media thickness (cIMT) measurement tool using B-mode ultrasound for stroke/cardiovascular risk assessment and its stratification. This is an anytime-anywhere clinical tool for routine screening and multi-center clinical trials. In this pilot study, the physician can upload ultrasound scans in one of the following formats (DICOM, JPEG, BMP, PNG, GIF or TIFF) directly into the proprietary cloud of AtheroPoint from the local server of the physician's office...
August 1, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27282868/circulating-adiponectin-and-carotid-intima-media-thickness-a-systematic-review-and-meta-analysis
#10
Karina Gasbarrino, Jessica Gorgui, Bénédicte Nauche, Robert Côté, Stella S Daskalopoulou
BACKGROUND: Adiponectin (APN) is an adipokine with insulin-sensitizing, anti-inflammatory, and vasculoprotective properties. Hypoadiponectinemia has been linked with disease states, such as obesity, type 2 diabetes, and cardiovascular disease. Carotid intima-media thickness (cIMT) is a strong and independent predictor of both coronary and cerebrovascular events, and has been used as a surrogate marker of subclinical atherosclerosis. The aim of this report is to systematically review the evidence on the relationship between APN and cIMT in a wide range of individuals...
July 2016: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/27038725/effects-of-statin-therapy-on-augmentation-index-as-a-measure-of-arterial-stiffness-a-systematic-review-and-meta-analysis
#11
REVIEW
Amirhossein Sahebkar, Ivan Pećin, Eugenia Tedeschi-Reiner, Giuseppe Derosa, Pamela Maffioli, Željko Reiner
OBJECTIVE: To evaluate the effects of statin therapy on augmentation index (AIx) as a measure of arterial stiffness using a meta-analysis of clinical trials. METHODS: The search included PubMed-Medline, Embase, SCOPUS, Web of Science and Google Scholar databases to identify randomized controlled trials investigating the effects of statin therapy on arterial stiffness measured as AIx. A random-effects model and generic inverse variance method were used for quantitative data synthesis...
June 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27038513/detection-of-carotid-atherosclerotic-plaque-neovascularization-using-contrast-enhanced-ultrasound-a-systematic-review-and-meta-analysis-of-diagnostic-accuracy-studies
#12
REVIEW
Runqing Huang, Sahar S Abdelmoneim, Caroline A Ball, Lara F Nhola, Ann M Farrell, Steven Feinstein, Sharon L Mulvagh
BACKGROUND: Intraplaque neovascularization is considered an important indicator of plaque vulnerability. Contrast-enhanced ultrasound (CEUS) of carotid arteries improves imaging of carotid intima-media thickness and permits real-time visualization of neovascularization of the atherosclerotic plaque. The authors conducted a systematic review and meta-analysis to evaluate the accuracy of CEUS-detected carotid atherosclerotic plaque. METHODS: A systematic search was performed to identify studies published in the MEDLINE, Embase, Scopus, and Web of Science databases from 2004 to June 2015...
June 2016: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/27026766/ivy-sign-in-moyamoya-disease
#13
Ali Kemal Sivrioglu, Muzaffer Saglam, Bulent Yildiz, Vania Anagnostakou, Osman Kizilkilic
Moyamoya disease is an idiopathic disease characterized by the progressive stenosis and collateral development of the distal internal carotid arteries. In this disease, several collateral vascular structures develop following stenosis and occlusion. The ivy sign is a characteristic Magnetic rezonance imaging (MRI) finding frequently encountered in patients with moyamoya. It can be observed both in post contrast T1-weighted images and Fluid attenuated inversion recovery (FLAIR) images. While this sign manifests in the form of contrasting on the cortical surfaces due to the formation of leptomeningeal collateral development and increased numbers of pial vascular webs on post contrast images, in FLAIR images it originates from the slow arterial flow in the leptomeningeal collateral vascular structures...
February 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/26922976/neurointerventional-management-of-carotid-webs-associated-with-recurrent-and-acute-cerebral-ischemic-syndromes
#14
A H Elmokadem, S A Ansari, R Sangha, S Prabhakaran, A Shaibani, M C Hurley
BACKGROUND: A carotid web can be defined as an endoluminal shelf-like projection often noted at the origin of the internal carotid artery (ICA) just beyond the bifurcation. Diagnosis of a carotid web as an underlying cause of recurrent ischemic stroke is infrequent and easily misdiagnosed as an atheromatous plaque. Surgery has traditionally been used to resect symptomatic lesions while there is no enough evidence supporting medical therapy as the sole management. To our knowledge there is only one report about carotid artery stenting (CAS) as a definite management of carotid web and no previous reports of acute large-vessel occlusions undergoing mechanical thrombectomy in the setting of carotid web as the etiology...
August 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/26861025/therapeutic-internal-carotid-or-vertebral-artery-occlusion-using-the-web-device
#15
Willem Jan van Rooij, Menno Sluzewski, Ratna Bechan, Jo Pp Peluso
The WEB device was used to occlude the internal carotid artery or vertebral artery as treatment for large aneurysms. The WEB could be placed accurately at the desired position inside the vessel. Two WEBs were sufficient to occlude the parent artery.
June 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/26826789/cardiovascular-risk-markers-in-patients-with-primary-aldosteronism-a-systematic-review-and-meta-analysis-of-literature-studies
#16
Pasquale Ambrosino, Roberta Lupoli, Anna Tortora, Marianna Cacciapuoti, Gelsy Arianna Lupoli, Paolo Tarantino, Aurelio Nasto, Matteo Nicola Dario Di Minno
BACKGROUND/OBJECTIVES: Several studies reported an increased cardiovascular (CV) morbidity and mortality in patients with primary aldosteronism (PA). We performed a meta-analysis on the impact of PA on major markers of CV risk. METHODS: Studies on the relationship between PA and common carotid artery intima-media thickness (CCA-IMT), prevalence of carotid plaques, flow-mediated dilation (FMD), nitrate-mediated dilation (NMD), pulse-wave velocity (PWV), augmentation index (AIx), and ankle-brachial index (ABI) were systematically searched in the PubMed, Web of Science, Scopus and EMBASE databases...
April 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/26736524/a-semantically-aided-architecture-for-a-web-based-monitoring-system-for-carotid-atherosclerosis
#17
Vassileios D Kolias, Giorgos Stamou, Spyretta Golemati, Giannis Stoitsis, Christos D Gkekas, Christos D Liapis, Konstantina S Nikita
Carotid atherosclerosis is a multifactorial disease and its clinical diagnosis depends on the evaluation of heterogeneous clinical data, such as imaging exams, biochemical tests and the patient's clinical history. The lack of interoperability between Health Information Systems (HIS) does not allow the physicians to acquire all the necessary data for the diagnostic process. In this paper, a semantically-aided architecture is proposed for a web-based monitoring system for carotid atherosclerosis that is able to gather and unify heterogeneous data with the use of an ontology and to create a common interface for data access enhancing the interoperability of HIS...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/26622927/internal-carotid-artery-web-doppler-ultrasound-with-ct-angiography-correlation
#18
Winnie Fu, Ann Crockett, Gavin Low, Vimal Patel
We present a case of an internal carotid web, detected on duplex ultrasound and confirmed by CT angiography. To our knowledge, this is only the third reported ultrasound case in the imaging literature. This vascular abnormality can cause a clinically significant carotid stenosis and is a risk factor for recurrent embolic cerebrovascular events. Due to small size and poor awareness among radiologists, carotid webs are often under-diagnosed on non-invasive imaging modalities. Improved awareness including knowledge of salient imaging features is useful as early diagnosis leading to appropriate intervention can eliminate the risk of future cerebrovascular events...
May 2015: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/26567373/impact-of-obstructive-sleep-apnea-syndrome-on-endothelial-function-arterial-stiffening-and-serum-inflammatory-markers-an-updated-meta-analysis-and-metaregression-of-18-studies
#19
REVIEW
Jiayang Wang, Wenyuan Yu, Mingxin Gao, Fan Zhang, Chengxiong Gu, Yang Yu, Yongxiang Wei
BACKGROUND: Obstructive sleep apnea syndrome (OSAS) has been indicated to contribute to the development of cardiovascular disease; however, the underlying mechanism remains unclear. This study aimed to test the hypothesis that OSAS may be associated with cardiovascular disease by elevating serum levels of inflammatory markers and causing arterial stiffening and endothelial dysfunction. METHODS AND RESULTS: Related scientific reports published from January 1, 2006, to June 30, 2015, were searched in the following electronic literature databases: PubMed, Excerpta Medica Database, ISI Web of Science, Directory of Open Access Journals, and the Cochrane Library...
November 2015: Journal of the American Heart Association
https://www.readbyqxmd.com/read/26552042/clinical-and-anatomical-follow-up-in-patients-with-aneurysms-treated-with-the-web-device-1-year-follow-up-report-in-the-cumulated-population-of-2-prospective-multicenter-series-webcast-and-french-observatory
#20
MULTICENTER STUDY
Laurent Pierot, Laurent Spelle, Andrew Molyneux, James Byrne
BACKGROUND: Flow disruption with WEB is an innovative endovascular approach for wide-neck bifurcation aneurysms. Initial series have shown a low complication rate with good efficacy. OBJECTIVE: To report clinical and anatomical results of the WEB treatment in the cumulated population of WEBCAST (WEB Clinical Assessment of Intrasaccular Aneurysm) and French Observatory series. METHODS: WEBCAST and French Observatory are single-arm, prospective, multicenter, Good Clinical Practice studies dedicated to the evaluation of WEB treatment...
January 2016: Neurosurgery
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