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cardiology meta analysis

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https://www.readbyqxmd.com/read/28905088/new-horizons-in-cardiac-innervation-imaging-introduction-of-novel-18-f-labeled-pet-tracers
#1
Ryohei Kobayashi, Xinyu Chen, Rudolf A Werner, Constantin Lapa, Mehrbod S Javadi, Takahiro Higuchi
Cardiac sympathetic nervous activity can be uniquely visualized by non-invasive radionuclide imaging techniques due to the fast growing and widespread application of nuclear cardiology in the last few years. The norepinephrine analogue (123)I-meta-iodobenzylguanidine ((123)I-MIBG) is a single photon emission computed tomography (SPECT) tracer for the clinical implementation of sympathetic nervous imaging for both diagnosis and prognosis of heart failure. Meanwhile, positron emission tomography (PET) imaging has become increasingly attractive because of its higher spatial and temporal resolution compared to SPECT, which allows regional functional and dynamic kinetic analysis...
September 13, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28844512/meta-analysis-of-usefulness-of-anticoagulation-after-transcatheter-aortic-valve-implantation
#2
REVIEW
Kinjal Banerjee, Kanhaiya Poddar, Stephanie Mick, Jonathon White, Amar Krishnaswamy, Douglas Johnston, Leonardo Rodriguez, E Murat Tuzcu, Samir Kapadia
Since the advent of bioprosthetic valves, the implications of long-term anticoagulation after valve replacement are unclear. There are very little data on outcomes of long-term anticoagulation after transcatheter aortic valve implantation (TAVI). Our aim was to conduct a systematic review of literature regarding anticoagulation after TAVI. The existing literature on anticoagulation after bioprosthetic valve replacement was thoroughly reviewed, including the most recent American College of Cardiology/American Heart Association 2017 guidelines for management of valvular disease, which is based on sparse, nonrandomized retrospective data...
August 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28810622/oral-n-acetylcysteine-for-prophylaxis-of-contrast-induced-nephropathy-in-patients-following-coronary-angioplasty-a-meta-analysis
#3
Jing-Xiu Li, En-Ze Jin, Long-Hao Yu, Yang Li, Nan-Nan Liu, Yu-Mei Dong, Xin Li, Xue-Qi Li
It is acknowledged that contrast-induced nephropathy (CIN) is a common cause of acute renal insufficiency after cardiac catheterization and affects mortality and morbidity. To date, it is unknown whether oral N-acetylcysteine (NAC) is able to prevent contrast-induced nephropathy (CIN) in patients undergoing coronary angioplasty. A meta-analysis of randomized controlled trials was performed to assess the effects of NAC in the prevention of CIN in patients following coronary angioplasty. A total of 19 studies published prior to January 2015 that investigated the efficacy of oral NAC for the prevention of CIN were collected from Medline, Cochrane and Embase databases and conference proceedings from cardiology and nephrology meetings...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28770625/clinical-implications-of-blood-material-interaction-and-drug-eluting-stent-polymers-in-review
#4
Hiroyoshi Mori, Anuj Gupta, Sho Torii, Emanuel Harari, Hiroyuki Jinnouchi, Renu Virmani, Aloke V Finn
Despite advances in drug-eluting stent (DES) technology, stent thrombosis (ST) remains the most feared complication with high morbidity and mortality. Areas covered: Stent related factors certainly play a role in the pathophysiology of ST and more recent data suggest coating technologies have the potential to favorable modify this risk though blood material interactions. Of the polymer coatings used in DES, fluorinated polymers in particular have shown significant promise in modifying the risk of ST through their preferential interactions with albumin which is believed to prevent the adhesion and aggregation of platelets to the stent surface and thus minimize thrombus formation...
August 11, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28747036/long-term-outcome-of-nonobstructive-versus-obstructive-hypertrophic-cardiomyopathy-a-systematic-review-and-meta-analysis
#5
Francesco Pelliccia, Vincenzo Pasceri, Giuseppe Limongelli, Camillo Autore, Cristina Basso, Domenico Corrado, Massimo Imazio, Claudio Rapezzi, Gianfranco Sinagra, Giuseppe Mercuro
BACKGROUND: Prognosis of hypertrophic cardiomyopathy (HCM) is particularly heterogeneous. Patients with nonobstructive HCM (NOCM) are thought to be at relatively low-risk as compared with obstructive HCM (HOCM) with no need of major treatment options. However, available evidence of NOCM comes mainly from tertiary centers where a referral bias is likely to occur. Aim of this study was to perform a systematic review and meta-analysis of the published literature on hypertrophic cardiomyopathy (HCM) in order to outline differences in presenting features and long-term outcome between NOCM and HOCM...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28706008/efficacy-and-safety-of-bortezomib-maintenance-in-patients-with-newly-diagnosed-multiple-myeloma-a-meta-analysis
#6
Chun-Yan Sun, Jun-Ying Li, Zhang-Bo Chu, Lu Zhang, Lei Chen, Yu Hu
Multiple myeloma (MM) is a B-cell neoplasm with a high incidence of relapse. Bortezomib has been extensively studied for the maintenance treatment of MM. Here, we carried out a meta-analysis to determine the efficacy and safety of maintenance therapy with bortezomib. We searched for clinical trials in PubMed (Medline), Embase (OVID), and the Cochrane Library. Two randomized controlled trials (RCTs) enrolling a total of 1338 patients were included. Bortezomib maintenance statistically significantly improved both progression-free survival (PFS) (hazard ratio (HR) 0...
August 31, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28700477/application-of-the-syntax-score-in-interventional-cardiology-a-systematic-review-and-meta-analysis
#7
REVIEW
Pravesh Kumar Bundhun, Yashna Sookharee, Anita Bholee, Feng Huang
BACKGROUND: Should the SYNTAX score be integrated in Interventional Cardiology? Should it really be considered as a vital decision-making tool in percutaneous coronary intervention (PCI)? To confirm the importance of this score, we aimed to systematically compare the postinterventional adverse cardiovascular outcomes which were observed in patients who were allotted a low versus a high SYNTAX score. METHODS: Randomized controlled trials and observational studies which were published from January 2007 to January 2017 were identified from MEDLINE, EMBASE, and the Cochrane databases using the searched terms 'SYNTAX score and percutaneous coronary intervention...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28669333/biomarkers-in-stable-coronary-artery-disease
#8
Jonas Rusnak, Christian Fastner, Michael Behnes, Kambis Mashayekhi, Martin Borggrefe, Ibrahim Akin
BACKGROUND: Coronary artery disease (CAD) is the most common reason for death in the western hemisphere. Therefore, a well-functioning risk-management has been established over the past decades with uprising interest in 'novel' biomarkers to predict adverse coronary events and detect patients with subclinical CAD. This review will focus on selected biomarkers belonging to the family of inflammatory markers (fibrinogen or hs-CRP) or to the family of lipid-associated markers (Lipoprotein associated PA2 or Lipoprotein a) and others are direct organ-specific biomarkers (hs-troponin, Cystatin C or NT-proBNP)...
June 30, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28658308/unprotected-left-main-revascularization-percutaneous-coronary-intervention-versus-coronary-artery-bypass-an-updated-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#9
Luca Testa, Azeem Latib, Mario Bollati, Rocco Antonio Montone, Antonio Colombo, Filippo Crea, Francesco Bedogni
BACKGROUND: The optimal treatment of unprotected left main (UPLM) with either PCI or CABG remains uncertain. AIM: The purpose of this study was to determine the comparative safety and efficacy of PCI versus CABG in patients with UPLM disease. METHODS: Search of BioMedCentral, CENTRAL, mRCT, PubMed, major cardiological congresses proceedings and references cross-check (updated November 2016). Outcomes were the rate of MACE [all cause death, MI, stroke], the rates of the individual components of MACE and the rate of target vessel revascularisation (TVR)...
2017: PloS One
https://www.readbyqxmd.com/read/28496093/prediction-of-new-onset-and-recurrent-atrial-fibrillation-by-complete-blood-count-tests-a-comprehensive-systematic-review-with-meta-analysis
#10
Alexander Weymann, Sadeq Ali-Hasan-Al-Saegh, Anton Sabashnikov, Aron-Frederik Popov, Seyed Jalil Mirhosseini, Tong Liu, Mohammadreza Lotfaliani, Michel Pompeu Barros de Oliveira Sá, William L L Baker, Senol Yavuz, Mohamed Zeriouh, Jae-Sik Jang, Hamidreza Dehghan, Lei Meng, Luca Testa, Fabrizio D'Ascenzo, Umberto Benedetto, Gary Tse, Luis Nombela-Franco, Pascal M Dohmen, Abhishek J Deshmukh, Cecilia Linde, Giuseppe Biondi-Zoccai, Gregg W Stone, Hugh Calkins, Integrated Meta-Analysis Of Cardiac Surgery And Cardiology-Group Imcsc-Group
BACKGROUND Atrial fibrillation (AF) is one of the most critical and frequent arrhythmias precipitating morbidities and mortalities. The complete blood count (CBC) test is an important blood test in clinical practice and is routinely used in the workup of cardiovascular diseases. This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of hematological parameters in the CBC test with new-onset and recurrent AF. MATERIAL AND METHODS We conducted a meta-analysis of observational studies evaluating hematologic parameters in patients with new-onset AF and recurrent AF...
May 12, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/28360407/predictive-role-of-coagulation-fibrinolytic-and-endothelial-markers-in-patients-with-atrial-fibrillation-stroke-and-thromboembolism-a-meta-analysis-meta-regression-and-systematic-review
#11
REVIEW
Alexander Weymann, Anton Sabashnikov, Sadeq Ali-Hasan-Al-Saegh, Aron-Frederik Popov, Seyed Jalil Mirhosseini, William L Baker, Mohammadreza Lotfaliani, Tong Liu, Hamidreza Dehghan, Senol Yavuz, Michel Pompeu Barros de Oliveira Sá, Jae-Sik Jang, Mohamed Zeriouh, Lei Meng, Fabrizio D'Ascenzo, Abhishek J Deshmukh, Guiseppe Biondi-Zoccai, Pascal M Dohmen, Hugh Calkins, Integrated Meta-Analysis Of Cardiac Cardiac Surgery And Cardiology-Group Imcsc-Group
BACKGROUND The pathophysiological mechanism associated with the higher prothrombotic tendency in atrial fibrillation (AF) is complex and multifactorial. However, the role of prothrombotic markers in AF remains inconclusive. MATERIAL AND METHODS We conducted a meta-analysis of observational studies evaluating the association of coagulation activation, fibrinolytic, and endothelial function with occurrence of AF and clinical adverse events. A comprehensive subgroup analysis and meta-regression was performed to explore potential sources of heterogeneity...
March 31, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/28330658/nonobstructive-coronary-artery-disease-by-coronary-ct-angiography-improves%C3%A2-risk-stratification-and-allocation%C3%A2-of-statin%C3%A2-therapy
#12
Hamed Emami, Richard A P Takx, Thomas Mayrhofer, Sumbal Janjua, Jakob Park, Amit Pursnani, Ahmed Tawakol, Michael T Lu, Maros Ferencik, Udo Hoffmann
OBJECTIVES: This study sought to determine prognostic value of nonobstructive coronary artery disease (CAD) for atherosclerotic cardiovascular disease (ASCVD) events and to determine whether incorporation of this information into the pooled cohort equation reclassifies recommendations for statin therapy as defined by the 2013 guidelines for cholesterol management of the American College of Cardiology and American Heart Association (ACC/AHA). BACKGROUND: Detection of nonobstructive CAD by coronary computed tomography angiography may improve risk stratification and permit individualized and more appropriate allocation of statin therapy...
September 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28303211/real-time-three-dimensional-echocardiography-characterization-of-cardiac-anatomy-and-function-current-clinical-applications-and-literature-review-update
#13
REVIEW
Omar Velasco, Morgan Q Beckett, Aaron W James, Megan N Loehr, Taylor G Lewis, Tahmin Hassan, Rajesh Janardhanan
Our review of real-time three-dimensional echocardiography (RT3DE) discusses the diagnostic utility of RT3DE and provides a comparison with two-dimensional echocardiography (2DE) in clinical cardiology. A Pubmed literature search on RT3DE was performed using the following key words: transthoracic, two-dimensional, three-dimensional, real-time, and left ventricular (LV) function. Articles included perspective clinical studies and meta-analyses in the English language, and focused on the role of RT3DE in human subjects...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28302997/platelets-cellular-and-functional-characteristics-in-patients-with-atrial-fibrillation-a-comprehensive-meta-analysis-and-systematic-review
#14
REVIEW
Alexander Weymann, Sadeq Ali-Hasan-Al-Saegh, Anton Sabashnikov, Aron-Frederik Popov, Seyed Jalil Mirhosseini, Luis Nombela-Franco, Luca Testa, Mohammadreza Lotfaliani, Mohamed Zeriouh, Tong Liu, Hamidreza Dehghan, Senol Yavuz, Michel Pompeu Barros de Oliveira Sá, William L Baker, Jae-Sik Jang, Mengqi Gong, Umberto Benedetto, Pascal M Dohmen, Fabrizio D'Ascenzo, Abhishek J Deshmukh, Giuseppe Biondi-Zoccai, Hugh Calkins, Gregg W Stone, Integrated Meta-Analysis Of Cardiac Surgery And Cardiology-Group Imcsc-Group
BACKGROUND This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of platelet cellular and functional characteristics including platelet count (PC), MPV, platelet distribution width (PDW), platelet factor 4, beta thromboglobulin (BTG), and p-selectin with the occurrence of atrial fibrillation (AF) and consequent stroke. MATERIAL AND METHODS We conducted a meta-analysis of observational studies evaluating platelet characteristics in patients with paroxysmal, persistent and permanent atrial fibrillations...
March 17, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/28252019/percutaneous-coronary-intervention-coronary-artery-bypass-surgery-and-the-syntax-score-a-systematic-review-and-meta-analysis
#15
Pravesh Kumar Bundhun, Chandra Mouli Yanamala, Feng Huang
The SYNTAX [Synergy Between percutaneous coronary intervention (PCI) With Taxus and coronary artery bypass surgery (CABG)] score is a decision-making tool in interventional cardiology. However, several facts still remain to be addressed: What about PCI or CABG with a low versus a high score respectively? And what about PCI with a low score versus CABG with a high score? Electronic databases were carefully searched for relevant publications. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated and the analysis was carried out by RevMan 5...
March 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28164009/infarct-related-artery-only-versus-complete-revascularization-in-st-segment-elevation-myocardial-infarction-and-multi-vessel-disease-a-meta-analysis
#16
Satyanarayana R Vaidya, Santhosh R Devarapally, Sameer Arora
BACKGROUND: The 2015 American College of Cardiology Foundation/American Heart Association (ACCF/AHA) focused update on primary percutaneous coronary intervention (PCI) for patients with ST-segment elevation myocardial infarction (STEMI) only gives a class II b (weak) indication for non-infarct artery intervention at the time of primary PCI. Recent randomized controlled trials, however, suggest strong evidence supporting complete revascularization. METHODS: A systematic search was conducted in PUBMED, MEDLINE, EMBASE and Cochrane central register for randomized controlled trials comparing complete versus infarct artery (IRA) only revascularization in patients with STEMI...
February 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28068415/same-day-discharge-versus-overnight-stay-in-the-hospital-following-percutaneous-coronary-intervention-in-patients-with-stable-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
REVIEW
Pravesh Kumar Bundhun, Mohammad Zafooruddin Sani Soogund, Wei-Qiang Huang
BACKGROUND: New research in interventional cardiology has shown the demand for percutaneous coronary interventions (PCI) to have increased tremendously. Effective treatment with a lower hospital cost has been the aim of several PCI capable centers. This study aimed to compare the adverse clinical outcomes associated with same day discharge versus overnight stay in the hospital following PCI in a population of randomized patients with stable coronary artery disease (CAD). METHODS: The National Library of Medicine (MEDLINE/PubMed), the Cochrane Registry of Randomized Controlled Trials and EMBASE databases were searched (from March to June 2016) for randomized trials comparing same-day discharge versus overnight stay in the hospital following PCI...
2017: PloS One
https://www.readbyqxmd.com/read/27993908/implantable-cardioverter-defibrillator-for-nonischemic-cardiomyopathy-an-updated-meta-analysis
#18
LETTER
Harsh Golwala, Navkaranbir Singh Bajaj, Garima Arora, Pankaj Arora
No abstract text is available yet for this article.
January 10, 2017: Circulation
https://www.readbyqxmd.com/read/27915163/impact-of-transfusion-on-stroke-after-cardiovascular-interventions-meta-analysis-of-comparative-studies
#19
REVIEW
Debora Brascia, Noemi Garcia-Medina, Eeva-Maija Kinnunen, Tuomas Tauriainen, Juhani Airaksinen, Fausto Biancari
PURPOSE: To evaluate the impact of transfusion on the development of stroke after cardiovascular interventions. METHODS: A literature search was performed to identify comparative studies on the impact of blood transfusion on the occurrence of stroke after adult cardiac surgery and interventional cardiology procedures. RESULTS: Twenty-four studies compared the outcome of 80 283 patients who received and 2 260 709 patients who did not receive blood transfusion after cardiovascular interventions...
April 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/27873229/subclinical-kidney-damage-in-hypertensive-patients-a-renal-window-opened-on-the-cardiovascular-system-focus-on-microalbuminuria
#20
Giuseppe Mulè, Antonella Castiglia, Claudia Cusumano, Emilia Scaduto, Giulio Geraci, Dario Altieri, Epifanio Di Natale, Onofrio Cacciatore, Giovanni Cerasola, Santina Cottone
The kidney is one of the major target organs of hypertension.Kidney damage represents a frequent event in the course of hypertension and arterial hypertension is one of the leading causes of end-stage renal disease (ESRD).ESRD has long been recognized as a strong predictor of cardiovascular (CV) morbidity and mortality. However, over the past 20 years a large and consistent body of evidence has been produced suggesting that CV risk progressively increases as the estimated glomerular filtration rate (eGFR) declines and is already significantly elevated even in the earliest stages of renal damage...
2017: Advances in Experimental Medicine and Biology
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