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Jay Sheth, Giridhar Anantharaman, Shruti Chandra, Mahesh Gopalakrishnan
Purpose: To describe management of residual branch vascular network (BVN) in polypoidal choroidal vasculopathy (PCV) by thermal laser photocoagulation of feeder vessel. Observations: Case report of sixty-four year old female with polypoidal choroidal vaculopathy (PCV) with moderate response to seven doses of intravitreal ranibizumab, six doses of intravitreal bevacizumab and one session of photodynamic therapy (PDT). The patient has resolved polyps but persistence of disease activity due to residual BVN and large pigment epithelial detachment (PED)...
March 2018: American Journal of Ophthalmology Case Reports
J Röling, H Schmid, M Fischereder, R Draenert, F D Goebel
Renal disease is becoming an increasingly prevalent entity in human immunodeficiency virus (HIV)-infected patients; it occurs in a variety of clinical settings and is associated with histopathological changes. HIV-related renal impairment can present as acute or chronic kidney disease; it can be caused directly or indirectly by HIV and/or by drug-related effects that are directly nephrotoxic or lead to changes in renal function by inducing metabolic vaculopathy and renal damage. Acute renal failure is frequently caused by the toxic effects of antiretroviral therapy or nephrotoxic antimicrobial substances used in the treatment of opportunistic infections...
May 15, 2006: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
A B Akosa, A M Elhag
Toxic epidermal necrolysis (TEN) is a rare dermatological emergency which is caused by drugs and results in a high morbidity and a mortality rate of 20-30%. Ten confirmed cases of TEN were retrieved and the sweat glands were examined. Abnormalities of the sweat duct were found in all the cases and included basal vaculopathy, increased lymphocytic infiltration, basal apoptosis, basal cell hyperplasia and necrosis of the duct. Destruction and loss of the distal duct was present in 40% of the cases and was accompanied by dilatation of the proximal duct...
August 1995: Journal of Cutaneous Pathology
R Hanno, J P Callen
We studied Gottron's papules in 11 cases of known dermatomyositis to determine whether the findings were similar to those in the poikilodermatous eruption usually biopsied in this disease. As in typical poikilodermatous dermatomyositis, basal layer vaculopathy, PAS-positive basement membrane thickening, upper dermal mucin deposition and a mild diffuse upper dermal mononuclear infiltrate were frequent findings. In contrast to poikilodermatous dermatomyositis, however, epidermal hyperplasia consisting of acanthosis or papillomatosis was often present and epidermal atrophy was rare...
October 1985: Journal of Cutaneous Pathology
W Banks Anderson, J A Wadsworth, M B Landers
Retinitis pigmentosa is occasionally associated with a vasculopathy of the Coats type. Although the clinical appearance of the vaculopathy is similar to that seen in the usual patient iwth Coats's disease, cases associated with retinitis pigmentosa are usually bilateral, equally common in females, and are not seen in childhood. These findings suggest a different etiological process. We speculate that the etiology in such cases may be related to the vascular narrowing and slower circulation known to occur in some retinitis pigmentosa patients...
1977: Advances in Experimental Medicine and Biology
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