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https://www.readbyqxmd.com/read/28439306/fibular-strut-graft-for-nonunited-femoral-neck-fractures-in-children
#1
A Elgeidi, A El-Negery
PURPOSE: To evaluate the clinical and radiological outcomes of using fibular strut grafts as a fixation device for non-united femoral neck fractures in children with or without subtrochanteric valgus osteotomy. METHODS: A total of 12 children with non-united femoral neck fractures (nine males and three females) with an average age of 8.2 years (5 to 12) were managed, and functional results evaluated, between July 2013 and July 2015. The mechanisms of injury were fall from a height in ten patients and road traffic accident in two cases...
2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28431804/prognostic-value-of-dynamic-mri-positive-enhancement-integral-color-mapping-in-osteosynthesis-of-undisplaced-femoral-neck-fractures
#2
Masatoshi Morimoto, Yoshinori Takahashi, Takahiro Kubo, Kosuke Sugiura, Yasuaki Tamaki, Shunichi Toki, Katsuyoshi Suganuma, Kazumasa Inoue, Keisuke Adachi, Takashi Chikawa, Koichi Sairyo, Akihiro Nagamachi
AIMS: The common treatment for an undisplaced femoral neck fracture is osteosynthesis. Two major complications of osteosynthesis are non-union and late collapse of the femoral head. We speculated that femoral head perfusion is one of the most important factors that affect the outcome of osteosynthesis after femoral neck fracture. We have preoperatively estimated femoral head perfusion by dynamic MRI positive enhancement integral color mapping (PEICM). The purpose of this study was to evaluate the outcomes of undisplaced femoral neck fractures based on PEICM...
April 18, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28430719/intertrochanteric-osteotomy-for-femoral-neck-non-union-does-undercorrection-result-in-an-acceptable-rate-of-femoral-neck-union
#3
Brandon J Yuan, David W Shearer, David P Barei, Sean E Nork
OBJECTIVES: To analyze the radiographic outcomes of intertrochanteric osteotomy for the treatment of femoral neck non-union with "undercorrection" of the Pauwels' angle and relative preservation of the proximal femoral anatomy. DESIGN: Retrospective cohort study SETTING:: Level-1 trauma center PATIENTS:: Thirty-two patients with established femoral neck non-unions that had been treated with intertrochanteric osteotomy were retrospectively identified through Current Procedural Terminology (CPT) codes...
April 18, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28426459/the-association-between-cmv-viremia-or-endoscopic-features-and-histopathological-characteristics-of-cmv-colitis-in-patients-with-underlying-ulcerative-colitis
#4
Hong Yang, Weixun Zhou, Hong Lv, Dongsheng Wu, Yunlu Feng, Huijun Shu, Meng Jin, Lingling Hu, Qiang Wang, Dong Wu, Jie Chen, Jiaming Qian
BACKGROUND: Cytomegalovirus (CMV) infection has been shown to be related to severe or steroid-refractory ulcerative colitis (UC) flare-ups. The aim of this study was to evaluate the endoscopic and pathological characteristics of CMV colitis in patients with UC and to assess the predictive value of the endoscopic and pathological features of CMV colitis. METHODS: A total of 50 consecutive UC patients with CMV infection who were admitted to Peking Union Medical College Hospital from 2010 to 2015 were enrolled in this study...
May 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28424852/clinical-application-of-bone-morphogenetic-proteins-for-bone-healing-a-systematic-review
#5
REVIEW
Gopal Shankar Krishnakumar, Alice Roffi, Davide Reale, Elizaveta Kon, Giuseppe Filardo
PURPOSE: This paper documents the existing evidence on bone morphogenetic proteins (BMPs) use for the treatment of bone fractures, non-union, and osteonecrosis, through a review of the clinical literature, underlying potential and limitations in terms of cost effectiveness and risk of complications. METHODS: A systematic review was performed on the PubMed database using the following string: (bone morphogenetic proteins OR BMPs) and (bone repair OR bone regeneration) including papers from 2000 to 2016...
April 19, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28420364/anterior-inferior-plating-versus-superior-plating-for-clavicle-fracture-a-meta-analysis
#6
Jie Ai, Shun-Li Kan, Hai-Liang Li, Hong Xu, Yang Liu, Guang-Zhi Ning, Shi-Qing Feng
BACKGROUND: The position of plate fixation for clavicle fracture remains controversial. Our objective was to perform a comprehensive review of the literature and quantify the surgical parameters and clinical indexes between the anterior inferior plating and superior plating for clavicle fracture. METHODS: PubMed, EMBASE, and the Cochrane Library were searched for randomized and non-randomized studies that compared the anterior inferior plating with the superior plating for clavicle fracture...
April 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28419886/total-hip-arthroplasty-for-patients-with-crowe-type-iv-developmental-dysplasia-of-the-hip-ten-years-results
#7
Wei-Nan Zeng, Jun-Li Liu, Fu-You Wang, Xin Zhang, Hua-Quan Fan, Guang-Xing Chen, Lin Guo, Xiao-Jun Duan, Qiang Zhou, Liu Yang
BACKGROUND AND OBJECTIVES: The aim of this study was to determine the rate of union, functional results and complications in patients with Crowe IV developmental dysplasia of the hip (DDH) who underwent cementless total hip arthroplasty (THA) with S-ROM prostheses and subtrochanteric transverse shortening osteotomy. METHODS: Forty-five patients (52 hips) operated between January 2005 and May 2008, with a mean age of 40.6 years at surgery were followed. The mean follow-up period was 9...
April 15, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28417290/unilateral-external-fixator-in-the-treatment-of-humeral-shaft-fractures-results-of-a-single-center-retrospective-study
#8
M Basso, M Formica, L Cavagnaro, M Federici, M Lombardi, F Lanza, L Felli
BACKGROUND: The aim of our work is to evaluate and critically analyze long-term clinical and radiological data of a new unilateral external fixator (MIKAI KIT FEP©-Mikai S.p.A, Genoa, Italy), in the treatment of humeral shaft fractures. MATERIALS AND METHODS: We reviewed 47 patients affected by humeral fractures that underwent surgery from July 2010 to March 2016 with unilateral external fixator. Demographic characteristics of the patients were recorded, which included age, sex and baseline comorbidities and mechanism of injury...
April 17, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28416034/cohabitation-and-union-dissolution-in-central-uganda-differences-between-cohabitors-and-non-cohabitors
#9
Charles Lwanga, Ishmael Kalule-Sabiti, Natal Ayiga
The aim of this paper was to establish whether the differences in the risks of union dissolution between cohabitors and non-cohabitors in Uganda have converged over time using event history data. Data were collected in 2013 from 1200 women in central Uganda using retrospective methods. Of these, 839 provided information on three types of first union: women who married directly (without first cohabiting), those who married following cohabitation and those who were still cohabiting. The data were analysed using decrement lifetable analysis...
April 18, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28412736/tumor-biology-clinicopathological-characteristics-and-prognosis-of-screen-detected-t1-invasive-non-palpable-breast-cancer-in-asymptomatic-chinese-women-2001-2014
#10
Bo Pan, Ru Yao, Yi-Dong Zhou, Qing-Li Zhu, Jie Shi, Qian-Qian Xu, Chang-Jun Wang, Shan-Shan You, Feng Mao, Yan Lin, Song-Jie Shen, Zhi-Yong Liang, Yu-Xin Jiang, Qiang Sun
BACKGROUND: Mammography screening usually detects low-risk breast cancer in the western world. However, little is known about the ultrasound and mammography screen-detected T1 invasive non-palpable breast cancer (NPBC) in asymptomatic Chinese women. RESULTS: With the increase of tumor size (T1a, b, c), lymph node positivity (8.7%, 18.3%, 26.0%, p = 0.018), pN (p = 0.028) and TNM stage (p = 0.035) increased accordingly. Tumor size (T1a, b, c) was correlated with high Ki-67 index (defined as ≥ 14%, 37...
February 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28410997/international-incidence-of-childhood-cancer-2001-10-a-population-based-registry-study
#11
Eva Steliarova-Foucher, Murielle Colombet, Lynn A G Ries, Florencia Moreno, Anastasia Dolya, Freddie Bray, Peter Hesseling, Hee Young Shin, Charles A Stiller
BACKGROUND: Cancer is a major cause of death in children worldwide, and the recorded incidence tends to increase with time. Internationally comparable data on childhood cancer incidence in the past two decades are scarce. This study aimed to provide internationally comparable local data on the incidence of childhood cancer to promote research of causes and implementation of childhood cancer control. METHODS: This population-based registry study, devised by the International Agency for Research on Cancer in collaboration with the International Association of Cancer Registries, collected data on all malignancies and non-malignant neoplasms of the CNS diagnosed before age 20 years in populations covered by high-quality cancer registries with complete data for 2001-10...
April 11, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28410753/retrospective-review-of-patients-with-atypical-bisphosphonate-related-proximal-femoral-fractures
#12
H K Phillips, S J Harrison, H Akrawi, S A Sidhom
INTRODUCTION: Patients may be at an increased risk of atypical proximal femoral fractures with prolonged bisphosphonate use. PATIENTS AND METHODS: This was a retrospective review of patients who sustained a subtrochanteric fracture of the femur in our department between April 2009 and March 2014. The radiographs were reviewed for features of atypical femoral fractures as described by the American Society of Bone Mineral Research. RESULTS: 185 patients were coded according to the National Hip Fracture Database as having sustained a subtrochanteric fracture of the femur...
April 4, 2017: Injury
https://www.readbyqxmd.com/read/28409514/neck-strength-and-self-reported-neck-dysfunction-what-is-the-impact-of-a-season-of-rugby-union
#13
Danielle M Salmon, S John Sullivan, Phil Handcock, Nancy J Rehrer, Brian Niven
BACKGROUND: Neck strength has been reported to reduce the incidence of concussions and neck injuries. However little is known about how neck strength changes over a playing season. AIM: To understand the impact a 20-week rugby season has on neck strength, neck pain (NP) and neck stiffness (NS) in a cohort of rugby players, relative to a non-contact control group. METHODS: This prospective cohort study employed a fixed-frame dynamometer to measure neck strength in a simulated contact posture in rugby players (n=32) and controls (n=15)...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28409134/anatomical-variations-of-pronator-teres-muscle-predispositional-role-for-nerve-entrapment
#14
Edie Benedito Caetano, Luiz Ângelo Vieira, Fábio Antonio Anversa Sprovieri, Guilherme Camargo Petta, Maurício Tadeu Nakasone, Bárbara Lívia Correa Serafim
OBJECTIVE: To assess the anatomical variations of the pronator teres muscle (PTM) and its implication in the compression of the median nerve, which passes through the humeral and ulnar heads of the PTM. METHODS: For the present study, 100 upper limbs from human cadavers from the anatomy laboratory were dissected. Forty-six specimens were male and four, female, whose aged ranged from 28 to 77 years; 27 were white and 23, non-white. A pilot study consisting of six hands from three fresh cadaver dissections was conducted to familiarize the authors with the local anatomy; these were not included in the present study...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28404484/health-research-capacity-building-in-georgia-a%C3%A2-case-based-needs-assessment
#15
A Squires, T Chitashvili, M Djibuti, L Ridge, D Chyun
OBJECTIVES: Research capacity building in the health sciences in low- and middle-income countries (LMICs) has typically focused on bench-science capacity, but research examining health service delivery and health workforce is equally necessary to determine the best ways to deliver care. The Republic of Georgia, formerly a part of the Soviet Union, has multiple issues within its healthcare system that would benefit from expended research capacity, but the current research environment needs to be explored prior to examining research-focused activities...
March 6, 2017: Public Health
https://www.readbyqxmd.com/read/28401593/low-dose-bmp-2-and-msc-dual-delivery-onto-coral-scaffold-for-critical-size-bone-defect-regeneration-in-sheep
#16
Adeline Decambron, Alexandre Fournet, Morad Bensidhoum, Mathieu Manassero, Frédéric Sailhan, Hervé Petite, Delphine Logeart-Avramoglou, Véronique Viateau
Tissue-engineered constructs (TECs) combining resorbable calcium-based scaffolds and mesenchymal stem cells (MSCs) have the capability to regenerate large bone defects. Inconsistent results have, however, been observed, with a lack of osteoinductivity as a possible cause of failure. This study aimed to evaluate the impact of the addition of low-dose bone morphogenetic protein-2 (BMP-2) to MSC-coral-TECs on the healing of clinically-relevant segmental bone defects in sheep. Coral granules were either seeded with autologous MSCs (bone marrow-derived) or loaded with BMP-2...
April 12, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28401362/carpal-scaphoid-non-union-treatment-a-retrospective-trial-comparing-simple-retrograde-percutaneous-screw-fixation-versus-percutaneous-screw-fixation-plus-pulsed-electromagnetic-fields-physiostim-%C3%A2
#17
Alexis Pereira, Juan José Hidalgo Díaz, Maurise Saur, Santiago Salazar Botero, Sybille Facca, Philippe Liverneaux
BACKGROUND: The purpose of this retrospective comparative study was to assess whether a complementary treatment by pulsed electromagnetic field could increase the bone-healing rate of scaphoid non-union without SNAC (scaphoid non-union advanced collapse) treated by retrograde percutaneous screw fixation. CASE DESCRIPTION: Eighteen patients with scaphoid non-union were included in this retrospective study. The group 1 was made of nine cases (seven stage IIA and two stage IIB) of scaphoid non-union treated by retrograde percutaneous screw fixation and pulsed electromagnetic fields (Physiostim(®))...
April 11, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28400874/locking-versus-non-locking-neutralization-plates-with-limited-excision-and-internal-fixation-for-treatment-of-extra-articular-type-a-distal-tibial-fractures
#18
Kai-Hua Zhou, Nong Chen
PURPOSE: This study aimed to compare the clinical, radiologic, and cost-effectiveness results between locking and non-locking plates for the treatment of extra-articular type A distal tibial fractures. METHODS: We performed a retrospective review of AO/OTA 42-A1, A2 distal tibial fractures treated by plates from January 2011 to June 2013. Patients were divided to the locking plate group or the non-locking plate group. Clinical outcomes, radiographic outcomes, and hospitalization fee were compared between the two plates groups...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28397554/sauv%C3%A3-kapandji-procedure-with-headless-compression-screw-in-patients-with-rheumatoid-arthritis
#19
Atsushi Maeda, Taku Suzuki, Masaki Hasegawa, Takashi Kuroiwa, Kanae Shizu, Katsuhiko Hayakawa, Takashi Tsuji, Katsuji Suzuki, Harumoto Yamada
OBJECTIVE: We examined the surgical outcomes of the Sauvé-Kapandji (S-K) procedure using a headless compression screw and a metal cancellous screw in patients with rheumatoid arthritis (RA). METHODS: This retrospective study included 41 RA patients who underwent the S-K procedure for distal radioulnar joint disorders with two screws: headless compression screws (HCS group, n = 20) and cannulated cancellous screws (CCS group, n = 21). Clinical and radiographic outcomes were assessed 1 year after surgery...
April 11, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28397317/evaluating-the-effectiveness-of-risk-minimisation-measures-the-application-of-a-conceptual-framework-to-danish-real-world-dabigatran-data
#20
REVIEW
Martin Erik Nyeland, Mona Vestergaard Laursen, Torbjörn Callréus
PURPOSE: For both marketing authorization holders and regulatory authorities, evaluating the effectiveness of risk minimization measures is now an integral part of pharmacovigilance in the European Union. The overall aim of activities in this area is to assess the performance of risk minimization measures implemented in order to ensure a positive benefit-risk balance in patients treated with a medicinal product. METHODS: Following a review of the relevant literature, we developed a conceptual framework consisting of four domains (data, knowledge, behaviour and outcomes) intended for the evaluation of risk minimization measures put into practice in the Danish health-care system...
April 11, 2017: Pharmacoepidemiology and Drug Safety
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