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https://www.readbyqxmd.com/read/28730395/dynamic-hip-screw-and-fibular-strut-graft-for-fixation-of-fresh-femoral-neck-fracture-with-posterior-comminution
#1
Adham Elgeidi, Abed El Negery, M Serry Abdellatif, Nabil El Moghazy
INTRODUCTION: Posterior comminution of the femoral neck fracture is a major cause of delayed and non-union owing to the loss of the buttressing effect against the posterior rotation. When a femoral neck fracture with posterior comminution is anatomically reduced, only the anterior portions of the femoral neck fracture surfaces are brought into contact leaving a posterior defect. The purpose of this study was to evaluate the use of fibular strut grafting and dynamic hip screw (DHS) for fresh femoral neck fractures with posterior comminution in young patient less than 50 years...
July 20, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28726040/assessing-predicted-age-specific-breast-cancer-mortality-rates-in-27-european-countries-by-2020
#2
R Clèries, R M Rooney, M Vilardell, J A Espinàs, T Dyba, J M Borras
BACKGROUND: We assessed differences in predicted breast cancer (BC) mortality rates, across Europe, by 2020, taking into account changes in the time trends of BC mortality rates during the period 2000-2010. METHODS: BC mortality data, for 27 European Union (EU) countries, were extracted from the World Health Organization mortality database. First, we compared BC mortality data between time periods 2000-2004 and 2006-2010 through standardized mortality ratios (SMRs) and carrying out a graphical assessment of the age-specific rates...
July 19, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28721484/a-comparison-of-external-fixation-and-locked-intramedullary-nailing-in-the-treatment-of-femoral-diaphysis-fractures-from-gunshot-injuries
#3
G Polat, H I Balci, O N Ergin, A Asma, C Şen, Ö Kiliçoğlu
INTRODUCTION: We studied the safety and incidence of complications from the treatment of gunshot-induced femur diaphysis fractures with locked intramedullary nailing in comparison to external fixation. METHODS: Patients who had femoral diaphysis fracture operations due to gunshot injuries (107 femurs of 99 patients) between 2003 and 2014 were retrospectively reviewed, and 66 femurs of 60 patients were place into two groups (Group A: intramedullary nailing-38 femurs of the 36 patients; Group B: external fixator-28 femurs of 24 patients)...
July 18, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28720985/conservative-management-of-odontoid-peg-fractures-long-term-follow-up
#4
REVIEW
Aheed Osman, Nabil A Alageli, D J Short, W S El Masri
OBJECTIVE: The aim of the study was to look at the long-term effects of conservative management of odontoid peg fractures. METHODS: We reviewed 48 consecutive patients with type II (32) and 16 type III, odontoid peg fractures. The clinical & radiological outcomes were assessed over an average period of follow up of 8 years. Union rate was determined and we discussed several factors that may affect it. Patients were treated conservatively with an average period of bed rest of 4 weeks followed by bracing for an average of 9 weeks...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28720979/first-report-of-phyllosticta-citricarpa-and-description-of-two-new-species-p-%C3%A2-paracapitalensis-and-p-%C3%A2-paracitricarpa-from-citrus-in-europe
#5
V Guarnaccia, J Z Groenewald, H Li, C Glienke, E Carstens, V Hattingh, P H Fourie, P W Crous
The genus Phyllosticta occurs worldwide, and contains numerous plant pathogenic, endophytic and saprobic species. Phyllosticta citricarpa is the causal agent of Citrus Black Spot disease (CBS), affecting fruits and leaves of several citrus hosts (Rutaceae), and can also be isolated from asymptomatic citrus tissues. Citrus Black Spot occurs in citrus-growing regions with warm summer rainfall climates, but is absent in countries of the European Union (EU). Phyllosticta capitalensis is morphologically similar to P...
June 2017: Studies in Mycology
https://www.readbyqxmd.com/read/28720347/transgenesis-affects-endogenous-soybean-allergen-levels-less-than-traditional-breeding
#6
Ryan C Hill, Brandon J Fast, Rod A Herman
The regulatory body that oversees the safety assessment of genetically modified (GM) crops in the European Union, the European Food Safety Authority (EFSA), uniquely requires that endogenous allergen levels be quantified as part of the compositional characterization of GM versions of crops, such as soybean, that are considered to be major allergenic foods. The value of this requirement for assessing food safety has been challenged for multiple reasons including negligible risk of altering allergen levels compared with traditional non-GM breeding...
July 15, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28716470/early-or-delayed-reconstruction-in-multi-ligament-knee-injuries-a-systematic-review-and-meta-analysis
#7
REVIEW
Erik Hohmann, Vaida Glatt, Kevin Tetsworth
BACKGROUND: Whether early or delayed surgical intervention in patients with multi-ligament injuries results in better outcomes, is of current and controversial debate. PURPOSE: The purpose of this study was to perform a meta-analysis comparing early versus late surgical treatment of multi-ligament knee injuries. METHODS: We performed a systematic review of Medline, Embase, Scopus, and Google Scholar to identify relevant studies in the English and German literature...
July 14, 2017: Knee
https://www.readbyqxmd.com/read/28716352/fatal-and-non-fatal-injury-outcomes-results-from-a-purposively-sampled-census-of-seven-rural-subdistricts-in-bangladesh
#8
Olakunle Alonge, Priyanka Agrawal, Abu Talab, Qazi S Rahman, Akm Fazlur Rahman, Shams El Arifeen, Adnan A Hyder
BACKGROUND: 90% of the global burden of injuries is borne by low-income and middle-income countries (LMICs). However, details of the injury burden in LMICs are less clear because of the scarcity of data and population-based studies. The Saving of Lives from Drowning project, implemented in rural Bangladesh, did a census on 1·2 million people to fill this gap. This Article describes the epidemiology of fatal and non-fatal injuries from the study. METHODS: In this study, we used data from the baseline census conducted as part of the Saving of Lives from Drowning (SoLiD) project...
August 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28713854/forced-migration-in-childhood-are-there-long-term-health-effects
#9
Jan M Saarela, Irma T Elo
Studies on the health of migrants have increased considerably in number in recent years, but little is still known about the long-term health effects associated with forced migration, and particularly for people who were forced to migrate as children. Data shortcomings together with the methodological challenges of studying migrant populations limit the ability to disentangle the roles of various factors that influence migrant health outcomes. Finland provides an unusual opportunity to study long-term health consequences associated with forced migration...
December 2016: SSM—Population Health
https://www.readbyqxmd.com/read/28712488/staged-reconstruction-of-diaphyseal-fractures-with-segmental-defects-surgical-and-patient-reported-outcomes
#10
S D Zoller, L A Cao, R A Smith, W Sheppard, E L Lord, C D Hamad, J H Ghodasra, C Lee, D Jeffcoat
INTRODUCTION: Two-stage limb reconstruction is an option for patients with critical size segmental bone defects following acute trauma or non-union. Reconstruction is technically demanding and associated with a high complication rate. Current protocols for limb reconstruction have well-documented challenges, and no study has reported on patient outcomes using a validated questionnaire. In this study, we aimed to examine the clinical and patient-centered outcomes following our surgical protocol for two-stage limb reconstruction following critical size segmental defects...
June 23, 2017: Injury
https://www.readbyqxmd.com/read/28712178/cognitive-potential-and-its-predictors-in-children-from-a-rural-district-of-pakistan
#11
Irum Gilani
BACKGROUND: Effective interventions are available to reduce cognitive deficit currently estimated to affect more than 200 million children under 5 years of age in developing countries. However, developing world's investment is negligible in this regard mainly because of non-existent global indicators to monitor progress with respect to the childhood cognitive development. Intelligence Quotient (IQ) or Full Scale Intelligence Quotient (FSIQ) is an indicator of the cognitive development...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28708781/fracture-site-mobility-at-six-weeks-following-humeral-shaft-fracture-predicts-nonunion-without-surgery
#12
Adam S Driesman, Nina Fisher, Raj Karia, Sanjit Konda, Kenneth A Egol
OBJECTIVES: To assess the presence of fracture site gross motion on physical examination to predict humeral shaft fracture progression to nonunion in patients managed non-operatively. DESIGN: Retrospective cohort study SETTING:: Single trauma level 1 institutional center PATIENTS:: Eighty-four consecutive patients undergoing non-operative treatment of a diaphyseal humeral shaft fracture were identified. The average age of the population was 48.3 years and 50% of the cohort was male...
July 8, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28708779/midshaft-fracures-of-the-clavicle-a-meta-analysis-comparing-surgical-fixation-via-anteroinferior-plating-versus-superior-plating
#13
Alex Nourian, Satvinder Dhaliwal, Sitaram Vangala, Peter S Vezeridis
OBJECTIVE: Tto compare the outcomes of clavicle fracture fixation using anteroinferior versus superior plate placement. METHODS: We performed a meta-analysis of studies that have reported on outcomes following superior or anteroinferior plate fixation for acute midshaft clavicle fractures (OTA 15-B). A computerized literature search in the Pubmed, Scopus, and Cochrane Library databases was utilized to identify relevant articles. Only full text articles without language restrictions were evaluated...
June 22, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28702927/3d-boolean-operations-in-virtual-surgical-planning
#14
Jerome Charton, Mathieu Laurentjoye, Youngjun Kim
PURPOSE: Boolean operations in computer-aided design or computer graphics are a set of operations (e.g. intersection, union, subtraction) between two objects (e.g. a patient model and an implant model) that are important in performing accurate and reproducible virtual surgical planning. This requires accurate and robust techniques that can handle various types of data, such as a surface extracted from volumetric data, synthetic models, and 3D scan data. METHODS: This article compares the performance of the proposed method (Boolean operations by a robust, exact, and simple method between two colliding shells (BORES)) and an existing method based on the Visualization Toolkit (VTK)...
July 12, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28702088/delayed-recognition-of-an-ipsilateral-femoral-neck-and-shaft-fracture-leading-to-preventable-subsequent-complications-a-case-report
#15
Sönke Labza, Isabella Fassola, Benedict Kunz, Wolfgang Ertel, Senat Krasnici
BACKGROUND: Ipsilateral femoral shaft and neck fractures are rare injuries, affecting mostly young patients who sustained high-energy traumas. In 19-50% of cases, the femoral fracture is misdiagnosed or overlooked at the initial presentation, with reportedly increased risk of complications such as non-union and avascular necrosis. We present a case of an ipsilateral femoral neck and shaft fracture, which was missed at initial presentation despite radiographic and computed tomography (CT) scan evaluation...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28698332/development-in-the-number-of-clinical-trial-applications-in-western-europe-from-2007-to-2015-retrospective-study-of-data-from-national-competent-authorities
#16
Tilde Dombernowsky, Merete Hædersdal, Ulrik Lassen, Simon Francis Thomsen
OBJECTIVE: To investigate the development in the number of applications for authorisation of clinical trials of medicines (CTAs) submitted annually to national competent authorities in 10 Western European member states of the European Union from 2007 to 2015. DESIGN: Registry study. SETTING: Data from national competent authorities. PARTICIPANTS: Germany, Italy, Spain, France, the UK, Belgium, the Netherlands, Austria, Denmark and Sweden...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28696381/cost-saving-opportunities-in-nsclc-therapy-by-optimized-diagnostics
#17
Ilija Nenadić, Jeanine Staber, Susanne Dreier, Guus Simons, Verena Schildgen, Michael Brockmann, Oliver Schildgen
With an incidence of 68 new cases per 100,000 people per year, an estimated total number of up to 350,000 new non-small-cell lung cancer (NSCLC) cases are diagnosed each year in the European Union. Up to 10% of NSCLC patients are eligible for therapy with novel ALK (anaplastic lymphoma kinase) inhibitors, as they have been diagnosed with a mutation in the gene coding for ALK. The ALK inhibitor therapy costs add up to approx. 9,000 € per patient per month, with treatment durations of up to one year. Recent studies have shown that up to 10% of ALK cases are misdiagnosed by nearly 40% of pathologic investigations...
July 11, 2017: Cancers
https://www.readbyqxmd.com/read/28687579/validation-of-the-8th-edition-of-the-uicc-ajcc-staging-system-for-nasopharyngeal-carcinoma-from-endemic-areas-in-the-intensity-modulated-radiotherapy-era
#18
Ling-Long Tang, Yu-Pei Chen, Yan-Ping Mao, Zi-Xian Wang, Rui Guo, Lei Chen, Li Tian, Ai-Hua Lin, Li Li, Ying Sun, Jun Ma
Background: In this study, we evaluated the 8th edition of the Union for International Cancer Control (UICC)/AJCC staging system for nasopharyngeal carcinoma (NPC) in an endemic area, with the aim of validating its applicability and providing further information for future refinements. Methods: A total of 1,790 patients with newly diagnosed, non-distant metastatic, histologically proven NPC treated with intensity-modulated radiotherapy (IMRT) were retrospectively reviewed. The performance of various staging systems was compared using the Akaike information criterion (AIC) and Harrell's concordance index (c-index)...
July 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28685556/use-of-supercharged-cover-screw-as-static-magnetic-field-generator-for-bone-healing-2nd-part-in-vivo-enhancement-of-bone-regeneration-in-rabbits
#19
F Bambini, A Santarelli, A Putignano, M Procaccini, G Orsini, D Di Iorio, L Memè, D Sartini, M Emanuelli, L Lo Muzio
In 1979, Pulsed electromagnetic fields (PEMFs) were approved by the Food and Drug Administration as an effective method in the treatment of non-unions. As well as PEMFs, also static magnetic fields (SMFs) have been widely investigated in orthopaedic studies. Even if the exact mechanism of action is not well understood, a large number of studies showed specific effects both at cellular and tissue levels. As bone fracture healing and osseointegration share the same biological events, the application of magnetic field stimulation in order to facilitate the osseointegration process has been suggested...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28681229/late-reconstruction-of-severe-open-book-deformities-of-the-pelvis-tips-and-tricks
#20
Christian Fang, Hatem Alabdulrahman, Roman Pfeifer, Ivan S Tarkin, Hans-Christoph Pape
BACKGROUND: The primary goal of treatment for open book pelvic injuries after high-energy trauma is to control haemorrhage and to close the pelvic ring anatomically. Less commonly, patients may present late with malunion or non-union. METHODS: We reviewed five operatively treated patients with delayed severe open book deformities who had a diastasis of more than 6 cm. We describe the pre-operative workup, surgical strategy and challenges experienced. They specifically include: extensive scar and contracture formation, malunion, urogenital prolapse and difficult reduction of vertical shear element...
July 5, 2017: International Orthopaedics
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