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Cystoid macular edema

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https://www.readbyqxmd.com/read/28328965/peripheral-blood-metabolic-and-inflammatory-factors-as-biomarkers-to-ocular-findings-in-diabetic-macular-edema
#1
Marc Figueras-Roca, Blanca Molins, Anna Sala-Puigdollers, Jessica Matas, Irene Vinagre, José Ríos, Alfredo Adán
AIMS: To study the association between peripheral blood metabolic and inflammatory factors and presence of diabetic macular edema (DME) and its related anatomic features in type 2 diabetic mellitus (T2DM) patients. MATERIAL AND METHODS: Observational cross-sectional study on a proof of concept basis. Seventy-six T2DM included patients were divided based on the presence (n = 58) or absence of DME (n = 18) according to optical coherence tomography (OCT). Ultra-widefield fluorescein angiography (UWFA) was performed in DME patients...
2017: PloS One
https://www.readbyqxmd.com/read/28320481/cystoid-macular-edema-associated-with-preservative-free-latanoprost-after-uncomplicated-cataract-surgery-case-report-and-review-of-the-literature
#2
Olga E Makri, Foteini N Tsapardoni, Panagiotis Plotas, Nikistratos Ifantis, Paraskevi T Xanthopoulou, Constantine D Georgakopoulos
BACKGROUND: Cystoid macular edema associated with latanoprost administration has been reported in patients after complicated cataract surgery with coexisting risk factors. We present the first case of preservative free latanoprost associated cystoid macular edema that occurred many months after uncomplicated cataract surgery. CASE PRESENTATION: A 65-year old Caucasian female presented in the Outpatients Clinic complaining of reduced vision and metamorphopsia in the right eye...
March 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28318349/visual-morbidity-and-ocular-complications-in-presumed-intraocular-tuberculosis-an-analysis-of-354-cases-from-a-non-endemic-population
#3
Dinesh Visva Gunasekeran, Bhaskar Gupta, Joao Cardoso, Carlos E Pavesio, Rupesh Agrawal
PURPOSE: To describe the visual morbidity associated with intraocular tuberculosis (TB) and to report ocular complications of intraocular TB. METHODS: Retrospective cohort study of patients diagnosed with intraocular TB at a tertiary referral eye care hospital in central London. Data on baseline and final best-corrected visual acuity (BCVA) along with ocular complications were collected and analyzed. RESULTS: In total, 354 patients with intraocular TB were included in this study...
March 20, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28301409/macular-macrovessels-associated-with-self-limiting-leakage-in-a-young-patient
#4
Alfonso Savastano, Ruggero Tartaro, Maria C Savastano, Stanislao Rizzo
PURPOSE: To report a case of congenital retinal macrovessels associated with cystoid macular edema. METHODS: We evaluated a 33-year-old, 2-month pregnant female with sudden decreased central vision in her left eye. RESULTS: We observed congenital retinal venous macrovessels that were related to cystoid macular edema development. After 3 months, her clinical condition improved with a spontaneous solution of the edema and visual acuity recovery...
March 15, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28296613/autologous-induced-stem-cell-derived-retinal-cells-for-macular-degeneration
#5
Michiko Mandai, Akira Watanabe, Yasuo Kurimoto, Yasuhiko Hirami, Chikako Morinaga, Takashi Daimon, Masashi Fujihara, Hiroshi Akimaru, Noriko Sakai, Yumiko Shibata, Motoki Terada, Yui Nomiya, Shigeki Tanishima, Masahiro Nakamura, Hiroyuki Kamao, Sunao Sugita, Akishi Onishi, Tomoko Ito, Kanako Fujita, Shin Kawamata, Masahiro J Go, Chikara Shinohara, Ken-Ichiro Hata, Masanori Sawada, Midori Yamamoto, Sachiko Ohta, Yasuo Ohara, Kenichi Yoshida, Junko Kuwahara, Yuko Kitano, Naoki Amano, Masafumi Umekage, Fumiyo Kitaoka, Azusa Tanaka, Chihiro Okada, Naoko Takasu, Seishi Ogawa, Shinya Yamanaka, Masayo Takahashi
We assessed the feasibility of transplanting a sheet of retinal pigment epithelial (RPE) cells differentiated from induced pluripotent stem cells (iPSCs) in a patient with neovascular age-related macular degeneration. The iPSCs were generated from skin fibroblasts obtained from two patients with advanced neovascular age-related macular degeneration and were differentiated into RPE cells. The RPE cells and the iPSCs from which they were derived were subject to extensive testing. A surgery that included the removal of the neovascular membrane and transplantation of the autologous iPSC-derived RPE cell sheet under the retina was performed in one of the patients...
March 16, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28281104/electroretinogram-and-visual-field-changes-in-a-case-of-birdshot-chorioretinopathy
#6
Hisham Elbaz, Volker Besgen, Klara Rechberger, Walter Sekundo, Eckart Apfelstedt-Sylla
PURPOSE: This case report explores the role of the visual field perimetry and electroretinogram (ERG) in cases of non-infectious uveitis in the assessment and monitoring of retinal function and response to treatment. METHODS: A 59-year-old Caucasian female presenting with bilateral posterior uveitis newly diagnosed as birdshot chorioretinopathy (BSCR) presenting with bilateral decrease in visual acuity and cystoid macular edema, as well as a paracentral scotoma in the right eye...
March 9, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28267110/cystoid-macular-edema-secondary-to-rituximab
#7
Marina Gilca, Pauline T Merrill
BACKGROUND/PURPOSE: To describe a case of bilateral macular edema appearing after treatment with rituximab. METHODS: This is a case report describing macular edema after rituximab infusions. The information was collected retrospectively through chart review. RESULTS: A 53-year-old patient known for IgG4-related disease of the face and sinuses presented with bilateral decreased visual acuity from cystoid macular edema shortly after undergoing two rituximab infusions...
March 6, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28257832/risk-factors-for-the-development-of-cataract-in-children-with-uveitis
#8
Tamar Blum-Hareuveni, Sophie Seguin-Greenstein, Michal Kramer, Guy Hareuveni, Yael Sharon, Ronit Friling, Lazha Sharief, Sue Lightman, Oren Tomkins-Netzer
PURPOSE: To determine the risk factors for the development of cataract in children with uveitis of any etiology. DESIGN: Cohort study METHODS: 247 eyes of 140 children with uveitis were evaluated for the development of vision affecting cataract. Demographic, clinical and treatment data were collected between the time of presentation and the first instance cataract was recorded or findings at final follow-up. Main outcome measures included prevalence of cataract and distribution by type of uveitis, incidence of new onset cataract time to cataract development and risk factors for the development of cataract...
February 28, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28248827/ranibizumab-for-retinal-vein-occlusion-predictive-factors-and-long-term-outcomes-in-real-life-data
#9
Irini Chatziralli, George Theodossiadis, Alexandros Chatzirallis, Efstratios Parikakis, Panagiotis Mitropoulos, Panagiotis Theodossiadis
PURPOSE: The purpose of the study was to evaluate the long-term anatomical and functional outcomes in patients with retinal vein occlusion (RVO), either central retinal vein occlusion or branch retinal vein occlusion, treated with intravitreal ranibizumab and to determine the predictive factors of the final visual outcome. METHODS: This retrospective study included 54 treatment-naive patients with macular edema due to RVO (25 with central retinal vein occlusion and 29 with branch retinal vein occlusion), who were treated with intravitreal ranibizumab (3 monthly injections and pro re nata)...
February 28, 2017: Retina
https://www.readbyqxmd.com/read/28243022/immediate-postoperative-intraocular-pressure-adjustment-reduces-risk-of-cystoid-macular-edema-after-uncomplicated-micro-incision-coaxial-phacoemulsification-cataract-surgery
#10
RANDOMIZED CONTROLLED TRIAL
John S Jarstad, Allison R Jarstad, Gary W Chung, Robert A Tester, Linda E Day
PURPOSE: To determine the accuracy of visual estimation of immediate postoperative intraocular pressure (IOP) following microincision cataract surgery (MICS) and the effect of immediate postoperative IOP adjustment on prevention of cystoid macular edema (CME). SETTING: Ambulatory surgical center. METHODS: Prospective, randomized analysis of 170 eyes in 135 patients with MICS, performed in a Medicare approved outpatient ambulatory surgery center...
February 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28237428/slow-release-dexamethasone-in-proliferative-vitreoretinopathy-a-prospective-randomized-controlled-clinical-trial
#11
Philip J Banerjee, Ana Quartilho, Catey Bunce, Wen Xing, Tapiwa M Zvobgo, Nicola Harris, David G Charteris
PURPOSE: To test the hypothesis that adjunctive slow-release dexamethasone implant (Ozurdex; Allergan Inc, Irvine, CA) can improve the outcomes of vitreoretinal surgery for established proliferative vitreoretinopathy (PVR). DESIGN: A 2-year, single-center, prospective, participant- and surgeon-masked randomized controlled clinical trial (EudraCT No. 2011-004498-96). PARTICIPANTS: A total of 140 patients requiring vitrectomy surgery with silicone oil for retinal detachment with established PVR (Grade C) were randomized to standard (control) or study treatment (adjunct) in a 1:1 allocation ratio...
February 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28237411/association-of-disorganization-of-retinal-inner-layers-with-visual-acuity-in-eyes-with-uveitic-cystoid-macular-edema
#12
Dilraj S Grewal, Matthew L O'Sullivan, Martina Kron, Glenn J Jaffe
PURPOSE: To determine whether disorganization of retinal inner layers (DRIL) assessed by spectral domain optical coherence tomography (SD-OCT) correlates with visual acuity (VA) in eyes with uveitic cystoid macular edema (CME). DESIGN: Secondary analysis of Randomized Clinical Trial data. METHODS: Fifty-six eyes of 42 patients with uveitic CME were prospectively imaged as part of the VISUAL-1 trial (Clinicaltrials.gov identifier NCT01138657)...
February 22, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28221257/intravitreal-dexamethasone-implant-in-retinitis-pigmentosa-related-cystoid-macular-edema
#13
Ahmad M Mansour, Huda Sheheitli, Cem Kucukerdonmez, Robert A Sisk, Raphael Moura, Marilita M Moschos, Luiz H Lima, Laila Al-Shaar, J Fernando Arevalo, Mauricio Maia, Robert E Foster, Ozcan Kayikcioglu, Igor Kozak, Shree Kurup, Hernando Zegarra, Roberto Gallego-Pinazo, Rola N Hamam, Riad A Bejjani, Esat Cinar, Ethem T Erakgün, Alan Kimura, Anderson Teixeira
PURPOSE: To report the clinical outcome after intravitreal dexamethasone implant in patients with retinitis pigmentosa and cystoid macular edema. METHODS: Multicenter retrospective case series of eyes with retinitis pigmentosa and cystoid macular edema that underwent intravitreal dexamethasone implant. Primary outcome measures were best-corrected visual acuity in LogMAR and central macular thickness. Statistical analyses used two-tailed comparison with Wilcoxon signed-rank test...
February 17, 2017: Retina
https://www.readbyqxmd.com/read/28219426/pseudophakic-cystoid-macular-edema-prevention-and-risk-factors-prospective-study-with-adjunctive-once-daily-topical-nepafenac-0-3-versus-placebo
#14
RANDOMIZED CONTROLLED TRIAL
Sean McCafferty, April Harris, Corin Kew, Tala Kassm, Lisa Lane, Jason Levine, Meisha Raven
BACKGROUND: Define the effectiveness of a topical non-steroidal anti-inflammatory drug (NSAID) added to topical steroid use after uncomplicated phacoemulsification for the prevention of pseudophakic cystoid macular edema (PCME) using a prospective, randomized, double-masked, placebo-controlled clinical study. METHODS: Eyes (1000) were randomized to placebo (497) or nepafenac 0.3% (503) used once daily, post-operatively for 5 weeks at two ophthalmology clinics. Diagnosis of PCME was made by clinical, ocular coherence tomography (OCT), and with fluorescein angiography confirmation...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28203470/unusual-presentation-of-type-1-idiopathic-macular-telangiectasia
#15
Zaïnab Bentaleb Machkour, Philippe Denis, Laurent Kodjikian
Purpose. To report unusual presentation of type 1A idiopathic macular telangiectasia (IMT). Methods. Two middle-aged women with bilateral IMT were examined. Results. Both patients presented with a gradual vision loss in both eyes. Fundus examination was unremarkable in one case and showed small macular telangiectasia in both eyes in the other case. Fluorescein angiography (FA) revealed early bilateral macular punctuated hyperfluorescence corresponding to the dilated capillaries in both cases. FA and fundus examination confirmed also the absence of vascular abnormalities in the middle or anterior fundus periphery in one case...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28203192/docetaxel-retinopathy-a-case-report
#16
Sylvia Nghiem-Buffet, Salomon Yves Cohen, Audrey Giocanti-Auregan
BACKGROUND: To report the use of En-face optical coherence tomography (OCT) in a patient treated with docetaxel and tamoxifen for breast cancer for the detection of macular edema (ME) without evidence of leakage on fluorescein angiography (FA). CASE PRESENTATION: A 52-year-old woman treated for breast cancer presented with bilateral visual loss for 2 months. FA showed no significant leakage while spectral-domain OCT scans of both eyes showed foveolar and parafoveolar cystic spaces in a moderately thickened macula...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28185180/primary-iris-claw-iol-retrofixation-with-intravitreal-triamcinolone-acetonide-in-cases-of-inadequate-capsular-support
#17
Aditya Kelkar, Rachana Shah, Viraj Vasavda, Jai Kelkar, Shreekant Kelkar
PURPOSE: To assess the outcomes and analyze complication rates following primary iris claw IOL retrofixation with intravitreal triamcinolone acetonide. METHODS: This is a retrospective interventional case series. Patients with poor capsular support-diagnosed preoperatively or owing to intraoperative complications-were treated with iris claw IOL retrofixation with intravitreal triamcinolone acetonide. The data were retrospectively analyzed. RESULTS: 104 eyes of 102 patients with poor capsular support who underwent the procedure between 2010 and 2013 were analyzed...
February 9, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28178068/features-of-the-macula-and-central-visual-field-and-fixation-pattern-in-patients-with-retinitis-pigmentosa
#18
Isil Sayman Muslubas, Murat Karacorlu, Serra Arf, Mumin Hocaoglu, Mehmet Giray Ersoz
PURPOSE: To evaluate macular features and fixation pattern in patients with retinitis pigmentosa (RP) compared with healthy controls, using spectral-domain optical coherence tomography and MP-1 microperimetry. METHODS: Eighty-one eyes of 81 patients with RP and 90 eyes of 90 healthy subjects were assessed. The central foveal thickness, subfoveal choroidal thickness, ellipsoid zone length, and the mean retinal sensitivities and fixation characteristics were evaluated by spectral-domain optical coherence tomography and MP-1 microperimetry...
February 7, 2017: Retina
https://www.readbyqxmd.com/read/28161829/effect-of-oral-niacin-on-central-retinal-vein-occlusion
#19
Michael W Gaynon, Yannis M Paulus, Ehsan Rahimy, Janet L Alexander, Sam E Mansour
PURPOSE: Niacin, a treatment for dyslipidemia, is known to induce vasodilation as a secondary effect. Previous instances of patients with chronic central retinal vein occlusion (CRVO) and cystoid macular edema (CME) have been observed to spontaneously improve when placed on systemic niacin for hypercholesterolemia. The purpose of this study was to evaluate the effects of niacin on CRVO and associated ocular complications. METHODS: A prospective, single-center, non-randomized, interventional case series of niacin for CRVO was conducted...
February 4, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28160192/study-of-aqueous-cytokines-in-patients-with-different-patterns-of-diabetic-macular-edema-based-on-optical-coherence-tomography
#20
Sabyasachi Bandyopadhyay, Samir Kumar Bandyopadhyay, Mita Saha, Abhik Sinha
PURPOSE: To compare aqueous angiogenic and inflammatory cytokine concentrations in different patterns of diabetic macular edema (DME) based on optical coherence tomography (OCT). METHODS: This prospective study was conducted between July 1, 2015, and March 31, 2016, for 9 months. Aqueous samples were obtained from 52 consecutive DME patients and 16 controls. DME patients were divided according to OCT patterns into diffuse retinal thickening (DRT; n = 17), cystoid macular edema (CME; n = 20) and serous retinal detachment (SRD; n = 15) groups...
February 3, 2017: International Ophthalmology
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